메뉴 건너뛰기




Volumn 37, Issue 15, 2009, Pages 5105-5113

BRCA2-dependent homologous recombination is required for repair of Arsenite-induced replication lesions in mammalian cells

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; BRCA1 PROTEIN; BRCA2 PROTEIN;

EID: 69849110187     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp538     Document Type: Article
Times cited : (34)

References (64)
  • 1
    • 0026498334 scopus 로고
    • Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water
    • Chen,C.J. et al. (1992) Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water. Br. J. Cancer, 66, 888-892.
    • (1992) Br. J. Cancer , vol.66 , pp. 888-892
    • Chen, C.J.1
  • 2
    • 0028919048 scopus 로고
    • Incidence of internal cancers and ingested inorganic arsenic: A seven-year follow-up study in Taiwan
    • Chiou,H.Y. et al. (1995) Incidence of internal cancers and ingested inorganic arsenic: A seven-year follow-up study in Taiwan. Cancer Res., 55, 1296-1300.
    • (1995) Cancer Res , vol.55 , pp. 1296-1300
    • Chiou, H.Y.1
  • 3
    • 0342902411 scopus 로고    scopus 로고
    • A retrospective lung cancer mortality study of people exposed to insoluble arsenic and radon
    • Liu,Y.T. and Chen,Z. (1996) A retrospective lung cancer mortality study of people exposed to insoluble arsenic and radon. Lung Cancer, 14(Suppl. 1), S137-S148.
    • (1996) Lung Cancer , vol.14 , Issue.SUPPL. 1
    • Liu, Y.T.1    Chen, Z.2
  • 4
    • 0025171686 scopus 로고
    • Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms
    • Chen,C.J. and Wang,C.J. (1990) Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms. Cancer Res., 50, 5470-5474.
    • (1990) Cancer Res , vol.50 , pp. 5470-5474
    • Chen, C.J.1    Wang, C.J.2
  • 5
    • 0033060359 scopus 로고    scopus 로고
    • Mortality for certain diseases in areas with high levels of arsenic in drinking water
    • Tsai,S.M., Wang,T.N. and Ko,Y.C. (1999) Mortality for certain diseases in areas with high levels of arsenic in drinking water. Arch. Environ. Health, 54, 186-193.
    • (1999) Arch. Environ. Health , vol.54 , pp. 186-193
    • Tsai, S.M.1    Wang, T.N.2    Ko, Y.C.3
  • 6
    • 13744261256 scopus 로고    scopus 로고
    • Some drinking-water disinfectants and contaminants, including arsenic
    • IARC
    • IARC (2004) Some drinking-water disinfectants and contaminants, including arsenic. IARC Monogr Eval Carcinog Risks Hum., 84, 1-477.
    • (2004) IARC Monogr Eval Carcinog Risks Hum , vol.84 , pp. 1-477
  • 7
    • 0001263837 scopus 로고    scopus 로고
    • WHO , Health criteria and other supporting information, WHO, Geneva, pp
    • WHO (1996) WHO guidelines for drinking water quality. Health criteria and other supporting information, WHO, Vol. 2, Geneva, pp. 940-949.
    • (1996) WHO guidelines for drinking water quality , vol.2 , pp. 940-949
  • 8
    • 0035230512 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism, and carcinogenicity of arsenic
    • Pott,W.A., Benjamin,S.A. and Yang,R.S. (2001) Pharmacokinetics, metabolism, and carcinogenicity of arsenic. Rev. Environ. Contam. Toxicol., 169, 165-214.
    • (2001) Rev. Environ. Contam. Toxicol , vol.169 , pp. 165-214
    • Pott, W.A.1    Benjamin, S.A.2    Yang, R.S.3
  • 9
    • 69849087469 scopus 로고    scopus 로고
    • IARC (1980) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, 23, Some Metals and Metallic Compounds. World Health Organisation, Geneva.
    • IARC (1980) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, Vol. 23, Some Metals and Metallic Compounds. World Health Organisation, Geneva.
  • 10
    • 0036803041 scopus 로고    scopus 로고
    • The role of biomethylation in toxicity and carcinogenicity of arsenic: A research update
    • Styblo,M. et al. (2002) The role of biomethylation in toxicity and carcinogenicity of arsenic: A research update. Environ. Health Perspect., 110(Suppl. 5), 767-771.
    • (2002) Environ. Health Perspect , vol.110 , Issue.SUPPL. 5 , pp. 767-771
    • Styblo, M.1
  • 11
    • 0038125071 scopus 로고    scopus 로고
    • Comparative activity of melarsoprol and arsenic trioxide in chronic B-cell leukemia lines
    • Konig,A. et al. (1997) Comparative activity of melarsoprol and arsenic trioxide in chronic B-cell leukemia lines. Blood, 90 562-570.
    • (1997) Blood , vol.90 , pp. 562-570
    • Konig, A.1
  • 13
    • 1642408690 scopus 로고    scopus 로고
    • Low dose exposure to sodium arsenite synergistically interacts with UV radiation to induce mutations and alter DNA repair in human cells
    • Danaee,H. et al. (2004) Low dose exposure to sodium arsenite synergistically interacts with UV radiation to induce mutations and alter DNA repair in human cells. Mutagenesis, 19, 143-148.
    • (2004) Mutagenesis , vol.19 , pp. 143-148
    • Danaee, H.1
  • 14
    • 0242362757 scopus 로고    scopus 로고
    • Modulation of DNA repair processes by arsenic and selenium compounds
    • Hartwig,A. et al. (2003) Modulation of DNA repair processes by arsenic and selenium compounds. Toxicology, 193, 161-169.
    • (2003) Toxicology , vol.193 , pp. 161-169
    • Hartwig, A.1
  • 15
    • 33845808430 scopus 로고    scopus 로고
    • Impact of arsenite and its methylated metabolites on PARP-1 activity, PARP-1 gene expression and poly(ADP-ribosyl)ation in cultured human cells
    • Walter,I. et al. (2007) Impact of arsenite and its methylated metabolites on PARP-1 activity, PARP-1 gene expression and poly(ADP-ribosyl)ation in cultured human cells. DNA Repair (Amst), 6, 61-70.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 61-70
    • Walter, I.1
  • 16
    • 0036801404 scopus 로고    scopus 로고
    • Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite
    • Bau,D.T. et al. (2002) Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite. Environ. Health Perspect., 110(Suppl. 5), 753-756.
    • (2002) Environ. Health Perspect , vol.110 , Issue.SUPPL. 5 , pp. 753-756
    • Bau, D.T.1
  • 17
    • 4243987748 scopus 로고    scopus 로고
    • Arsenic induces oxidative DNA damage in mammalian cells
    • Kessel,M. et al. (2002) Arsenic induces oxidative DNA damage in mammalian cells. Mol. Cell Biochem., 234-235, 301-308.
    • (2002) Mol. Cell Biochem , vol.234-235 , pp. 301-308
    • Kessel, M.1
  • 18
    • 0035325084 scopus 로고    scopus 로고
    • Formamidopyrimidine-DNA glycosylase enhances arsenic-induced DNA strand breaks in PHA-stimulated and unstimulated human lymphocytes
    • Li,D. et al. (2001) Formamidopyrimidine-DNA glycosylase enhances arsenic-induced DNA strand breaks in PHA-stimulated and unstimulated human lymphocytes. Environ. Health Perspect., 109, 523-526.
    • (2001) Environ. Health Perspect , vol.109 , pp. 523-526
    • Li, D.1
  • 19
    • 0042771971 scopus 로고    scopus 로고
    • The role of oxidative DNA damage in human arsenic carcinogenesis: Detection of 8-hydroxy-2 - deoxyguanosine in arsenic-related Bowen's disease
    • Matsui,M. et al. (1999) The role of oxidative DNA damage in human arsenic carcinogenesis: Detection of 8-hydroxy-2 - deoxyguanosine in arsenic-related Bowen's disease. J. Invest. Dermatol., 113, 26-31.
    • (1999) J. Invest. Dermatol , vol.113 , pp. 26-31
    • Matsui, M.1
  • 20
    • 0035426039 scopus 로고    scopus 로고
    • Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells
    • Wang,T.S. et al. (2001) Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells. Free Radic. Biol. Med. 31, 321-330.
    • (2001) Free Radic. Biol. Med , vol.31 , pp. 321-330
    • Wang, T.S.1
  • 21
    • 1542399123 scopus 로고    scopus 로고
    • Arsenic-induced DNA hypomethylation affects chromosomal instability in mammalian cells
    • Sciandrello,G. et al. (2004) Arsenic-induced DNA hypomethylation affects chromosomal instability in mammalian cells. Carcinogenesis 25, 413-417.
    • (2004) Carcinogenesis , vol.25 , pp. 413-417
    • Sciandrello, G.1
  • 22
    • 0030885707 scopus 로고    scopus 로고
    • Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression
    • Zhao,C.Q. et al. (1997) Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc. Natl Acad. Sci. USA, 94, 10907-10912.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 10907-10912
    • Zhao, C.Q.1
  • 23
    • 0034235541 scopus 로고    scopus 로고
    • Arsenic mediates cell proliferation and gene expression in the bladder epithelium: Association with activating protein-1 transactivation
    • Simeonova,P.P. et al. (2000) Arsenic mediates cell proliferation and gene expression in the bladder epithelium: Association with activating protein-1 transactivation. Cancer Res., 60, 3445-3453.
    • (2000) Cancer Res , vol.60 , pp. 3445-3453
    • Simeonova, P.P.1
  • 24
    • 0033600897 scopus 로고    scopus 로고
    • Arsenic disrupts cellular levels of p53 and mdm2: A potential mechanism of carcinogenesis
    • Hamadeh,H.K. et al. (1999) Arsenic disrupts cellular levels of p53 and mdm2: A potential mechanism of carcinogenesis. Biochem. Biophys. Res. Commun., 263, 446-449.
    • (1999) Biochem. Biophys. Res. Commun , vol.263 , pp. 446-449
    • Hamadeh, H.K.1
  • 25
    • 45949112003 scopus 로고    scopus 로고
    • Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis
    • Shen,S. et al. (2008) Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis. Mol. Carcinog., 47, 508-518.
    • (2008) Mol. Carcinog , vol.47 , pp. 508-518
    • Shen, S.1
  • 26
    • 0035863397 scopus 로고    scopus 로고
    • Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3
    • Jiang,X.H. et al. (2001) Arsenic trioxide induces apoptosis in human gastric cancer cells through up-regulation of p53 and activation of caspase-3. Int. J. Cancer, 91, 173-179.
    • (2001) Int. J. Cancer , vol.91 , pp. 173-179
    • Jiang, X.H.1
  • 27
    • 0037350049 scopus 로고    scopus 로고
    • Inorganic and dimethylated arsenic species induce cellular p53
    • Filippova,M. and Duerksen-Hughes,P.J. (2003) Inorganic and dimethylated arsenic species induce cellular p53. Chem. Res. Toxicol., 16 423-431.
    • (2003) Chem. Res. Toxicol , vol.16 , pp. 423-431
    • Filippova, M.1    Duerksen-Hughes, P.J.2
  • 28
    • 0023905947 scopus 로고
    • A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication
    • Fuller,L.F. and Painter,R.B. (1988) A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication. Mutat. Res., 193, 109-121.
    • (1988) Mutat. Res , vol.193 , pp. 109-121
    • Fuller, L.F.1    Painter, R.B.2
  • 29
    • 0028960511 scopus 로고
    • Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
    • Blunt,T. et al. (1995) Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell, 80, 813-823.
    • (1995) Cell , vol.80 , pp. 813-823
    • Blunt, T.1
  • 30
    • 0019956767 scopus 로고
    • A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange
    • Thompson,L.H. et al. (1982) A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange. Mutat. Res., 95, 427-440.
    • (1982) Mutat. Res , vol.95 , pp. 427-440
    • Thompson, L.H.1
  • 31
    • 0029071063 scopus 로고
    • Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene
    • Tebbs,R.S. et al. (1995) Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene. Proc. Natl Acad. Sci. USA, 92, 6354-6358.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 6354-6358
    • Tebbs, R.S.1
  • 32
    • 0026078809 scopus 로고
    • Cytogenetic characterization of the ionizing radiation-sensitive Chinese hamster mutant irs1
    • Tucker,J.D. et al. (1991) Cytogenetic characterization of the ionizing radiation-sensitive Chinese hamster mutant irs1. Mutat. Res. 254, 143-152.
    • (1991) Mutat. Res , vol.254 , pp. 143-152
    • Tucker, J.D.1
  • 33
    • 0034306365 scopus 로고    scopus 로고
    • Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation
    • Griffin,C.S. et al. (2000) Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation. Nat. Cell Biol., 2, 757-761.
    • (2000) Nat. Cell Biol , vol.2 , pp. 757-761
    • Griffin, C.S.1
  • 34
    • 0036136316 scopus 로고    scopus 로고
    • Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions
    • Kraakman-van der Zwet,M. et al. (2002) Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions. Mol. Cell Biol., 22, 669-679.
    • (2002) Mol. Cell Biol , vol.22 , pp. 669-679
    • Kraakman-van der Zwet, M.1
  • 35
    • 0027299417 scopus 로고
    • Arsenic-induced DNA-strand breaks associated with DNA-protein crosslinks in human fetal lung fibroblasts
    • Dong,J.T. and Luo,X.M. (1993) Arsenic-induced DNA-strand breaks associated with DNA-protein crosslinks in human fetal lung fibroblasts. Mutat. Res., 302, 97-102.
    • (1993) Mutat. Res , vol.302 , pp. 97-102
    • Dong, J.T.1    Luo, X.M.2
  • 36
    • 0029019287 scopus 로고
    • Methods for the quantification of DNA double-strand breaks determined from the distribution of DNA fragment sizes measured by pulsed-field gel electrophoresis
    • Cedervall,B. et al. (1995) Methods for the quantification of DNA double-strand breaks determined from the distribution of DNA fragment sizes measured by pulsed-field gel electrophoresis. Radiat. Res., 143, 8-16.
    • (1995) Radiat. Res , vol.143 , pp. 8-16
    • Cedervall, B.1
  • 37
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent,D.C., Hoeijmakers,J.H. and Kanaar,R. (2001) Chromosomal stability and the DNA double-stranded break connection. Nat. Rev. Genet., 2, 196-206.
    • (2001) Nat. Rev. Genet , vol.2 , pp. 196-206
    • van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 38
    • 0030584084 scopus 로고    scopus 로고
    • Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
    • Baumann,P., Benson,F.E. and West,S.C. (1996) Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell, 87, 757-766.
    • (1996) Cell , vol.87 , pp. 757-766
    • Baumann, P.1    Benson, F.E.2    West, S.C.3
  • 39
    • 0028957889 scopus 로고
    • Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes
    • Haaf,T. et al. (1995) Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc. Natl Acad. Sci. USA, 92, 2298-2302.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2298-2302
    • Haaf, T.1
  • 40
    • 0037090535 scopus 로고    scopus 로고
    • Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage
    • Essers,J. et al. (2002) Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. EMBO J., 21 2030-2037.
    • (2002) EMBO J , vol.21 , pp. 2030-2037
    • Essers, J.1
  • 41
    • 0032546733 scopus 로고    scopus 로고
    • A partial hprt gene duplication generated by non-homologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination
    • Helleday,T., Arnaudeau,C. and Jenssen,D. (1998) A partial hprt gene duplication generated by non-homologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination. J. Mol. Biol., 279, 687-694.
    • (1998) J. Mol. Biol , vol.279 , pp. 687-694
    • Helleday, T.1    Arnaudeau, C.2    Jenssen, D.3
  • 42
    • 33751278712 scopus 로고    scopus 로고
    • Cellular functions of the BRCA tumour-suppressor proteins
    • Boulton,S.J. (2006) Cellular functions of the BRCA tumour-suppressor proteins. Biochem. Soc. Trans., 34 (Pt 5), 633-645.
    • (2006) Biochem. Soc. Trans , vol.34 , Issue.PART 5 , pp. 633-645
    • Boulton, S.J.1
  • 43
    • 0023807621 scopus 로고
    • Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks
    • Avemann,K. et al. (1988) Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks. Mol. Cell Biol., 8, 3026-3034.
    • (1988) Mol. Cell Biol , vol.8 , pp. 3026-3034
    • Avemann, K.1
  • 44
    • 0025812689 scopus 로고
    • Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
    • Ryan,A.J. et al. (1991) Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res., 19, 3295-3300.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3295-3300
    • Ryan, A.J.1
  • 45
    • 0027139317 scopus 로고
    • Interaction between replication forks and topoisomerase I-DNA cleavable complexes: Studies in a cell-free SV40 DNA replication system
    • Tsao,Y.P. et al. (1993) Interaction between replication forks and topoisomerase I-DNA cleavable complexes: Studies in a cell-free SV40 DNA replication system. Cancer Res., 53, 5908-5914.
    • (1993) Cancer Res , vol.53 , pp. 5908-5914
    • Tsao, Y.P.1
  • 46
    • 0034124053 scopus 로고    scopus 로고
    • Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5′-phosphorylated DNA double-strand breaks by replication runoff
    • Strumberg,D. et al. (2000) Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5′-phosphorylated DNA double-strand breaks by replication runoff. Mol. Cell. Biol., 20, 3977-3987.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 3977-3987
    • Strumberg, D.1
  • 47
    • 23344444636 scopus 로고    scopus 로고
    • Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
    • Saleh-Gohari,N. et al. (2005) Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol. Cell. Biol., 25, 7158-7169.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 7158-7169
    • Saleh-Gohari, N.1
  • 48
    • 0037972159 scopus 로고    scopus 로고
    • Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA
    • Schwerdtle,T. et al. (2003) Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA. Carcinogenesis, 24, 967-974.
    • (2003) Carcinogenesis , vol.24 , pp. 967-974
    • Schwerdtle, T.1
  • 49
    • 0018118897 scopus 로고
    • Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha
    • Ikegami,S. et al. (1978) Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha. Nature, 275, 458-460.
    • (1978) Nature , vol.275 , pp. 458-460
    • Ikegami, S.1
  • 50
    • 33847630719 scopus 로고    scopus 로고
    • Co-ordination of DNA single strand break repair. DNA Repair of small base lesions in DNA - from molecular biology to phenotype
    • Dianov,G.L. and Parsons,J.L. (2007) Co-ordination of DNA single strand break repair. DNA Repair of small base lesions in DNA - from molecular biology to phenotype. DNA repair (Amst.), 6, 454-460.
    • (2007) DNA repair (Amst.) , vol.6 , pp. 454-460
    • Dianov, G.L.1    Parsons, J.L.2
  • 51
    • 0035179345 scopus 로고    scopus 로고
    • Association of blood arsenic levels with increased reactive oxidants and decreased antioxidant capacity in a human population of northeastern Taiwan
    • Wu,M.M. et al. (2001) Association of blood arsenic levels with increased reactive oxidants and decreased antioxidant capacity in a human population of northeastern Taiwan. Environ. Health Perspect. 109, 1011-1017.
    • (2001) Environ. Health Perspect , vol.109 , pp. 1011-1017
    • Wu, M.M.1
  • 52
    • 0242691094 scopus 로고    scopus 로고
    • DNA damage in blood cells from children exposed to arsenic and lead in a mining area
    • Yanez,L. et al. (2003) DNA damage in blood cells from children exposed to arsenic and lead in a mining area. Environ. Res., 93 231-240.
    • (2003) Environ. Res , vol.93 , pp. 231-240
    • Yanez, L.1
  • 53
    • 65449145195 scopus 로고    scopus 로고
    • Inhibition of PARP-1 by arsenite interferes with repair of oxidative DNA damage
    • Ding,W. et al. (2009) Inhibition of PARP-1 by arsenite interferes with repair of oxidative DNA damage. J. Biol. Chem., 284, 6809-6817.
    • (2009) J. Biol. Chem , vol.284 , pp. 6809-6817
    • Ding, W.1
  • 54
    • 30344477649 scopus 로고    scopus 로고
    • Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes
    • Ding,W., Hudson,L.G. and Liu,K.J. (2005) Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes. Mol. Cell. Biochem., 279, 105-112.
    • (2005) Mol. Cell. Biochem , vol.279 , pp. 105-112
    • Ding, W.1    Hudson, L.G.2    Liu, K.J.3
  • 55
    • 0028120082 scopus 로고
    • Sister-chromatid exchange (SCE) among individuals chronically exposed to arsenic in drinking water
    • Lerda,D. (1994) Sister-chromatid exchange (SCE) among individuals chronically exposed to arsenic in drinking water. Mutat. Res., 312, 111-120.
    • (1994) Mutat. Res , vol.312 , pp. 111-120
    • Lerda, D.1
  • 56
    • 0037427930 scopus 로고    scopus 로고
    • Chromosomal aberrations and sister chromatid exchanges in individuals exposed to arsenic through drinking water in West Bengal, India
    • Mahata,J. et al. (2003) Chromosomal aberrations and sister chromatid exchanges in individuals exposed to arsenic through drinking water in West Bengal, India. Mutat. Res., 534, 133-143.
    • (2003) Mutat. Res , vol.534 , pp. 133-143
    • Mahata, J.1
  • 57
    • 38549115259 scopus 로고    scopus 로고
    • hOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo
    • Mateuca,R.A. et al. (2008) hOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo. Mutagenesis, 23, 35-41.
    • (2008) Mutagenesis , vol.23 , pp. 35-41
    • Mateuca, R.A.1
  • 58
    • 44949247264 scopus 로고    scopus 로고
    • DNA repair deficiency leads to susceptibility to develop arsenic-induced premalignant skin lesions
    • Banerjee,M. et al. (2008) DNA repair deficiency leads to susceptibility to develop arsenic-induced premalignant skin lesions. Int. J. Cancer, 123, 283-287.
    • (2008) Int. J. Cancer , vol.123 , pp. 283-287
    • Banerjee, M.1
  • 59
    • 17144377127 scopus 로고    scopus 로고
    • Arsenic trioxide: New clinical experience with an old medication in hematologic malignancies
    • Douer,D. and Tallman,M.S. (2005) Arsenic trioxide: New clinical experience with an old medication in hematologic malignancies. J. Clin. Oncol., 23, 2396-2410.
    • (2005) J. Clin. Oncol , vol.23 , pp. 2396-2410
    • Douer, D.1    Tallman, M.S.2
  • 60
    • 25144469413 scopus 로고    scopus 로고
    • Arsenic trioxide: An anti cancer missile with multiple warheads
    • Gazitt,Y. and Akay,C. (2005) Arsenic trioxide: An anti cancer missile with multiple warheads. Hematology, 10, 205-213.
    • (2005) Hematology , vol.10 , pp. 205-213
    • Gazitt, Y.1    Akay, C.2
  • 61
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose)polymerase
    • Bryant,H.E. et al. (2005) Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose)polymerase. Nature, 434, 913-917.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1
  • 62
    • 34147182310 scopus 로고    scopus 로고
    • Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial
    • Thomas,H.D. et al. (2007) Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial. Mol. Cancer Ther., 6, 945-956.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 945-956
    • Thomas, H.D.1
  • 63
    • 39849097680 scopus 로고    scopus 로고
    • Resistance to therapy caused by intragenic deletion in BRCA2
    • Edwards,S.L. et al. (2008) Resistance to therapy caused by intragenic deletion in BRCA2. Nature, 451, 1111-1115.
    • (2008) Nature , vol.451 , pp. 1111-1115
    • Edwards, S.L.1
  • 64
    • 2642547251 scopus 로고    scopus 로고
    • Chromosomal aberrations in arsenic-exposed human populations: A review with special reference to a comprehensive study in West Bengal, India
    • Mahata,J. et al. (2004) Chromosomal aberrations in arsenic-exposed human populations: A review with special reference to a comprehensive study in West Bengal, India. Cytogenet Genome Res, 104, 359-364.
    • (2004) Cytogenet Genome Res , vol.104 , pp. 359-364
    • Mahata, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.