Attenuation of DNA damage-induced p53 expression by arsenic: A possible mechanism for arsenic co-carcinogenesis

Molecular Carcinogenesis

Volumn 47, Issue 7, 2008, Pages 508-518

  Shen, Gwen ^a   Lee, Jane ^a   Weinfeld, Michael ^a   Le, X Chris ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Arsenic; BPDE DNA adducts; Co carcinogenicity; DNA repair; p53

Indexed keywords

ARSENIC; BENZO[A]PYRENE; MONOMETHYLARSONOUS ACID; PROTEIN P48; PROTEIN P53; PROTEIN P62; SERINE; TRANSCRIPTION FACTOR IIH; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP C PROTEIN; BENZO(A)PYRENE 7,8 DIHYDRODIOL 9,10 EPOXIDE DNA; BENZO(A)PYRENE-7,8-DIHYDRODIOL-9,10-EPOXIDE-DNA; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; DDB2 PROTEIN, HUMAN; DNA BINDING PROTEIN; ORGANOMETALLIC COMPOUND; P62 PROTEIN, HUMAN; RNA BINDING PROTEIN; XPA PROTEIN, HUMAN; XPC PROTEIN, HUMAN;

ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DOWN REGULATION; EXCISION REPAIR; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; CELL CULTURE; COCARCINOGENESIS; DNA REPAIR; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; WESTERN BLOTTING;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ARSENIC; BLOTTING, WESTERN; CELLS, CULTURED; COCARCINOGENESIS; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; FIBROBLASTS; HUMANS; ORGANOMETALLIC COMPOUNDS; PHOSPHORYLATION; RNA-BINDING PROTEINS; TRANSCRIPTION FACTOR TFIIH; TUMOR SUPPRESSOR PROTEIN P53; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 45949112003     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20406     Document Type: Article

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