메뉴 건너뛰기




Volumn 206, Issue 2, 2009, Pages 233-242

Effect of the metabotropic glutamate antagonist MPEP on striatal expression of the Homer family proteins in levodopa-treated hemiparkinsonian rats

Author keywords

DeltaFosB; Dyskinesias; Glutamate; Homer; Levodopa; Parkinson's disease

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; APOMORPHINE; BENSERAZIDE PLUS LEVODOPA; DOPAMINE DERIVATIVE; LEVODOPA; METABOTROPIC RECEPTOR 5; PROTEIN HOMER 1A; PROTEIN HOMER 1B; PROTEIN HOMER 1C; SODIUM CHLORIDE; TRANSCRIPTION FACTOR DELTA FOSB; TYROSINE 3 MONOOXYGENASE;

EID: 69549105683     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-009-1600-x     Document Type: Article
Times cited : (12)

References (97)
  • 3
    • 34147160157 scopus 로고    scopus 로고
    • Differential expression of Homer 1 gene by acute and chronic administration of antipsychotics and dopamine transporter inhibitors in the rat forebrain
    • A Ambesi-Impiombato F Panariello C Dell'Aversano C Tomasetti G Muscettola A de Bartolomeis 2007 Differential expression of Homer 1 gene by acute and chronic administration of antipsychotics and dopamine transporter inhibitors in the rat forebrain Synapse 61 429 439
    • (2007) Synapse , vol.61 , pp. 429-439
    • Ambesi-Impiombato, A.1    Panariello, F.2    Dell'Aversano, C.3    Tomasetti, C.4    Muscettola, G.5    De Bartolomeis, A.6
  • 4
    • 0033428178 scopus 로고    scopus 로고
    • Striatal fosB expression is causally linked with L-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease
    • M Andersson A Hilbertson MA Cenci 1999 Striatal fosB expression is causally linked with L-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease Neurobiol Dis 6 461 474
    • (1999) Neurobiol Dis , vol.6 , pp. 461-474
    • Andersson, M.1    Hilbertson, A.2    Cenci, M.A.3
  • 5
    • 0037330231 scopus 로고    scopus 로고
    • Time course of striatal DeltaFosB-like immunoreactivity and prodynorphin mRNA levels after discontinuation of chronic dopaminomimetic treatment
    • M Andersson JE Westin MA Cenci 2003 Time course of striatal DeltaFosB-like immunoreactivity and prodynorphin mRNA levels after discontinuation of chronic dopaminomimetic treatment Eur J Neurosci 17 661 666
    • (2003) Eur J Neurosci , vol.17 , pp. 661-666
    • Andersson, M.1    Westin, J.E.2    Cenci, M.A.3
  • 6
    • 0034548876 scopus 로고    scopus 로고
    • Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer 1 proteins and neuronal excitation
    • F Ango JP Pin JC Tu B Xiao PF Worley J Bockaert L Fagni 2000 Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer 1 proteins and neuronal excitation J Neurosci 20 8710 8716
    • (2000) J Neurosci , vol.20 , pp. 8710-8716
    • Ango, F.1    Pin, J.P.2    Tu, J.C.3    Xiao, B.4    Worley, P.F.5    Bockaert, J.6    Fagni, L.7
  • 7
    • 33645090418 scopus 로고    scopus 로고
    • Prolonged blockade of NMDA or mGLuR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease
    • MT Armentero R Fancellu G Nappi P Bramanti F Blandini 2006 Prolonged blockade of NMDA or mGLuR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease Neurobiol Dis 22 1 9
    • (2006) Neurobiol Dis , vol.22 , pp. 1-9
    • Armentero, M.T.1    Fancellu, R.2    Nappi, G.3    Bramanti, P.4    Blandini, F.5
  • 8
    • 0034332480 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
    • H Awad GW Hubert Y Smith AI Levey PJ Conn 2000 Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus J Neurosci 20 7871 7879
    • (2000) J Neurosci , vol.20 , pp. 7871-7879
    • Awad, H.1    Hubert, G.W.2    Smith, Y.3    Levey, A.I.4    Conn, P.J.5
  • 9
    • 0032527883 scopus 로고    scopus 로고
    • A complex program of striatal gene expression induced by dopaminergic stimulation
    • JD Berke RF Paletzki GJ Aronson SE Hyman CR Gerfen 1998 A complex program of striatal gene expression induced by dopaminergic stimulation J Neurosci 18 5301 5310
    • (1998) J Neurosci , vol.18 , pp. 5301-5310
    • Berke, J.D.1    Paletzki, R.F.2    Aronson, G.J.3    Hyman, S.E.4    Gerfen, C.R.5
  • 10
    • 0036774049 scopus 로고    scopus 로고
    • Move to the rhythm: Oscillations in the subthalamic nucleus-external globus pallidus network
    • MD Bevan PJ Magill D Terman JP Bolam CJ Wilson 2002 Move to the rhythm: oscillations in the subthalamic nucleus-external globus pallidus network Trends Neurosci 25 525 531
    • (2002) Trends Neurosci , vol.25 , pp. 525-531
    • Bevan, M.D.1    Magill, P.J.2    Terman, D.3    Bolam, J.P.4    Wilson, C.J.5
  • 12
    • 0036662945 scopus 로고    scopus 로고
    • Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism
    • N Breysse C Baunez W Spooren F Gasparini M Amalric 2002 Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism J Neurosci 22 5669 5678
    • (2002) J Neurosci , vol.22 , pp. 5669-5678
    • Breysse, N.1    Baunez, C.2    Spooren, W.3    Gasparini, F.4    Amalric, M.5
  • 13
    • 0141856474 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats
    • N Breysse M Almaric P Salin 2003 Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats J Neurosci 23 8302 8309
    • (2003) J Neurosci , vol.23 , pp. 8302-8309
    • Breysse, N.1    Almaric, M.2    Salin, P.3
  • 14
    • 0027400588 scopus 로고
    • Electrophysiology of dopamine-denervated striatal neurons
    • P Calabresi NB Mercuri G Sancesario G Bernardi 1993 Electrophysiology of dopamine-denervated striatal neurons Brain 116 433 452
    • (1993) Brain , vol.116 , pp. 433-452
    • Calabresi, P.1    Mercuri, N.B.2    Sancesario, G.3    Bernardi, G.4
  • 16
    • 0036389371 scopus 로고    scopus 로고
    • Transcription factors involved in the pathogenesis of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease
    • MA Cenci 2002 Transcription factors involved in the pathogenesis of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease Amino Acids 23 105 109
    • (2002) Amino Acids , vol.23 , pp. 105-109
    • Cenci, M.A.1
  • 17
    • 0031925945 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA
    • MA Cenci CS Lee A Björklund 1998 L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA Eur J Neurosci 10 2694 2706
    • (1998) Eur J Neurosci , vol.10 , pp. 2694-2706
    • Cenci, M.A.1    Lee, C.S.2    Björklund, A.3
  • 18
    • 0032835969 scopus 로고    scopus 로고
    • Changes in the regional and compartmental distribution of FosB- and JunB-like immunoreactivity induced in the dopamine-denervated rat striatum by acute or chronic L-dopa treatment
    • MA Cenci A Tranberg M Andersson A Hilbertson 1999 Changes in the regional and compartmental distribution of FosB- and JunB-like immunoreactivity induced in the dopamine-denervated rat striatum by acute or chronic L-dopa treatment Neuroscience 94 515 527
    • (1999) Neuroscience , vol.94 , pp. 515-527
    • Cenci, M.A.1    Tranberg, A.2    Andersson, M.3    Hilbertson, A.4
  • 19
    • 0642345900 scopus 로고    scopus 로고
    • Striatal glutamatergic mechanisms and extrapyramidal movement disorders
    • TN Chase F Bibbiani JD Oh 2003 Striatal glutamatergic mechanisms and extrapyramidal movement disorders Neurotox Res 5 139 146
    • (2003) Neurotox Res , vol.5 , pp. 139-146
    • Chase, T.N.1    Bibbiani, F.2    Oh, J.D.3
  • 20
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • PJ Conn JP Pin 1997 Pharmacology and functions of metabotropic glutamate receptors Ann Rev Pharmacol Toxicol 37 205 37
    • (1997) Ann Rev Pharmacol Toxicol , vol.37 , pp. 205-37
    • Conn, P.J.1    Pin, J.P.2
  • 21
    • 0037139302 scopus 로고    scopus 로고
    • Distribution of synaptic localization of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS
    • C Corti L Aldegheri P Somogyi F Ferraguti 2002 Distribution of synaptic localization of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS Neuroscience 110 403 420
    • (2002) Neuroscience , vol.110 , pp. 403-420
    • Corti, C.1    Aldegheri, L.2    Somogyi, P.3    Ferraguti, F.4
  • 22
  • 24
    • 0035282715 scopus 로고    scopus 로고
    • Molecular determinants of metabotropic glutamate receptor signaling
    • DOI 10.1016/S0165-6147(00)01635-7, PII S0165614700016357
    • A De Blasi PJ Conn J Pin F Nicoletti 2001 Molecular determinants of metabotropic glutamate receptor signaling Trends Pharmacol Sci 22 114 120 (Pubitemid 32181842)
    • (2001) Trends in Pharmacological Sciences , vol.22 , Issue.3 , pp. 114-120
    • De Blasi, A.1    Conn, P.J.2    Pin, J.-P.3    Nicoletti, F.4
  • 25
    • 33645050113 scopus 로고    scopus 로고
    • Effects of group i metabotropic glutamate receptors blockade in experimental models of Parkinson's disease
    • A Dekundy A Pietraszek D Schaefer MA Cenci W Danysz 2006 Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease Brain Res Bull 69 318 326
    • (2006) Brain Res Bull , vol.69 , pp. 318-326
    • Dekundy, A.1    Pietraszek, A.2    Schaefer, D.3    Cenci, M.A.4    Danysz, W.5
  • 26
    • 0033974271 scopus 로고    scopus 로고
    • Alterations in subunit expression, composition, and phosphorylation of striatal N-methyl-D-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease
    • AW Dunah Y Wang RP Yasuda K Kameyama RL Huganir BB Wolfe DG Standaert 2000 Alterations in subunit expression, composition, and phosphorylation of striatal N-methyl-D-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease Mol Pharmacol 57 342 352
    • (2000) Mol Pharmacol , vol.57 , pp. 342-352
    • Dunah, A.W.1    Wang, Y.2    Yasuda, R.P.3    Kameyama, K.4    Huganir, R.L.5    Wolfe, B.B.6    Standaert, D.G.7
  • 27
    • 34250928307 scopus 로고
    • Verteilung von Noradrenalin and Dopamin(3-Hydroxytyramin) im Gejirn des Menschen und ihr Verhalten bei Erkrankungen des extrapyramidalen systems
    • H Ehringer O Honykiewicz 1960 Verteilung von Noradrenalin and Dopamin(3-Hydroxytyramin) im Gejirn des Menschen und ihr Verhalten bei Erkrankungen des extrapyramidalen systems Klinische Wochenschrift 38 1236 1239
    • (1960) Klinische Wochenschrift , vol.38 , pp. 1236-1239
    • Ehringer, H.1    Honykiewicz, O.2
  • 28
    • 0028556522 scopus 로고
    • NMDA receptor blockade reverses motor response alterations induced by levodopa
    • TM Engber SM Papa RC Boldry TN Chase 1994 NMDA receptor blockade reverses motor response alterations induced by levodopa NeuroReport 5 2586 2588
    • (1994) NeuroReport , vol.5 , pp. 2586-2588
    • Engber, T.M.1    Papa, S.M.2    Boldry, R.C.3    Chase, T.N.4
  • 29
    • 0038699101 scopus 로고    scopus 로고
    • Homer as both a scaffold and transduction molecule
    • L Fagni PF Worley F Ango 2002 Homer as both a scaffold and transduction molecule SciSTKE 137 RE8
    • (2002) SciSTKE , vol.137 , pp. 8
    • Fagni, L.1    Worley, P.F.2    Ango, F.3
  • 30
    • 2342470026 scopus 로고    scopus 로고
    • Identification and functional roles of metabotropic glutamate receptor-interacting proteins
    • L Fagni F Ango J Perroy J Bockaert 2004 Identification and functional roles of metabotropic glutamate receptor-interacting proteins Semin Cell Dev Biol 15 289 298
    • (2004) Semin Cell Dev Biol , vol.15 , pp. 289-298
    • Fagni, L.1    Ango, F.2    Perroy, J.3    Bockaert, J.4
  • 31
    • 0034109726 scopus 로고    scopus 로고
    • The spectrum of levodopa-induced dyskinesias
    • S Fahn 2000 The spectrum of levodopa-induced dyskinesias Ann Neurol 47 suppl 1746 1752
    • (2000) Ann Neurol , vol.47 , Issue.SUPPL. , pp. 1746-1752
    • Fahn, S.1
  • 32
    • 34248575534 scopus 로고    scopus 로고
    • Levodopa in the treatment of Parkinson's disease
    • S Fahn 2006 Levodopa in the treatment of Parkinson's disease J Neural Transm Suppl 71 1 5
    • (2006) J Neural Transm Suppl , vol.71 , pp. 1-5
    • Fahn, S.1
  • 33
    • 0242302346 scopus 로고    scopus 로고
    • MGluRs: A target for pharmacotherapy in Parkinson's disease
    • JA Feeley Kearney RL Albin 2003 mGluRs: a target for pharmacotherapy in Parkinson's disease Exp Neurol 184 S30 S36
    • (2003) Exp Neurol , vol.184
    • Feeley Kearney, J.A.1    Albin, R.L.2
  • 34
    • 9744226444 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors and striatal synaptic plasticity: Implications for neurological diseases
    • P Gubellini A Pisani D Centonze G Bernardi P Calabresi 2004 Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases Prog Neurobiol 74 271 300
    • (2004) Prog Neurobiol , vol.74 , pp. 271-300
    • Gubellini, P.1    Pisani, A.2    Centonze, D.3    Bernardi, G.4    Calabresi, P.5
  • 36
    • 2542431131 scopus 로고    scopus 로고
    • Rationale for and use of NMDA receptor antagonists in Parkinson's disease
    • PJ Hallet DG Standaert 2004 Rationale for and use of NMDA receptor antagonists in Parkinson's disease Pharmacol Ther 102 155 174
    • (2004) Pharmacol Ther , vol.102 , pp. 155-174
    • Hallet, P.J.1    Standaert, D.G.2
  • 37
    • 14744290753 scopus 로고    scopus 로고
    • Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease
    • PJ Hallet AW Dunah P Ravenscroft S Zhou E Bezard AR Crossman JM Brotchie DG Standaert 2005 Alterations of striatal NMDA receptor subunits associated with the development of dyskinesia in the MPTP-lesioned primate model of Parkinson's disease Neuropharmacology 48 503 516
    • (2005) Neuropharmacology , vol.48 , pp. 503-516
    • Hallet, P.J.1    Dunah, A.W.2    Ravenscroft, P.3    Zhou, S.4    Bezard, E.5    Crossman, A.R.6    Brotchie, J.M.7    Standaert, D.G.8
  • 38
    • 69549126782 scopus 로고    scopus 로고
    • The mGluR5 receptor antagonist SIB-1830 reduces L-Dopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease
    • Abs 200.217
    • Hill MP, McGuire SG, Crossman AR, Brotchie JM (2001) The mGluR5 receptor antagonist SIB-1830 reduces L-Dopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease. Abstr Soc Neurosci 27, Abs 200.217
    • (2001) Abstr Soc Neurosci , vol.27
    • Hill, M.P.1    McGuire, S.G.2    Crossman, A.R.3    Brotchie, J.M.4
  • 39
    • 0013920522 scopus 로고
    • Dopamine (3-hydroxytyramine) and brain function
    • O Hornykiewicz 1966 Dopamine (3-hydroxytyramine) and brain function Pharmacol Rev 18 925 964
    • (1966) Pharmacol Rev , vol.18 , pp. 925-964
    • Hornykiewicz, O.1
  • 41
    • 0344069774 scopus 로고    scopus 로고
    • Narrow beneficial effect of dextromethorphan on levodopa-induced motor response alterations in an experimental model of parkinsonism
    • A Jiménez C Marin M Bonastre E Tolosa 1999 Narrow beneficial effect of dextromethorphan on levodopa-induced motor response alterations in an experimental model of parkinsonism Brain Res 839 190 193
    • (1999) Brain Res , vol.839 , pp. 190-193
    • Jiménez, A.1    Marin, C.2    Bonastre, M.3    Tolosa, E.4
  • 42
    • 34347250872 scopus 로고    scopus 로고
    • Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors
    • PJ Kammermeier PF Worley 2007 Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors Proc Natl Acad Sci U S A 104 6055 6660
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 6055-6660
    • Kammermeier, P.J.1    Worley, P.F.2
  • 43
    • 0032508574 scopus 로고    scopus 로고
    • Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors
    • A Kato F Ozawa F Saitoh Y Fukazawa H Sugiyama K Inokuchi 1998 Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors J Biol Chem 273 23969 23975
    • (1998) J Biol Chem , vol.273 , pp. 23969-23975
    • Kato, A.1    Ozawa, F.2    Saitoh, F.3    Fukazawa, Y.4    Sugiyama, H.5    Inokuchi, K.6
  • 44
    • 0030798541 scopus 로고    scopus 로고
    • Expression of groups one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus
    • JA Kerner DG Standaert JB Jr Penney AB Yung GB Landwehrmeyer 1997 Expression of groups one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus Brain Res Mol Brain Res 48 259 269
    • (1997) Brain Res Mol Brain Res , vol.48 , pp. 259-269
    • Kerner, J.A.1    Standaert, D.G.2    Penney Jr., J.B.3    Yung, A.B.4    Landwehrmeyer, G.B.5
  • 46
    • 36549085132 scopus 로고    scopus 로고
    • Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts L-DOPA-induced dyskinesias in a rodent model of Parkinson's disease
    • G Levandis E Bazzini MT Armentero G Nappi F Blandini 2008 Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts L-DOPA-induced dyskinesias in a rodent model of Parkinson's disease Neurobiol Dis 29 161 168
    • (2008) Neurobiol Dis , vol.29 , pp. 161-168
    • Levandis, G.1    Bazzini, E.2    Armentero, M.T.3    Nappi, G.4    Blandini, F.5
  • 47
    • 0025302149 scopus 로고
    • Bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons
    • N Lindefors R Ungerstedt 1990 Bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons Neurosci Lett 115 248 252
    • (1990) Neurosci Lett , vol.115 , pp. 248-252
    • Lindefors, N.1    Ungerstedt, R.2
  • 49
    • 14944372499 scopus 로고    scopus 로고
    • The scaffold protein Homer 1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons
    • L Mao L Yang Q Tang S Samdani G Zhang JQ Wang 2005 The scaffold protein Homer 1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons J Neurosci 25 2741 2752
    • (2005) J Neurosci , vol.25 , pp. 2741-2752
    • Mao, L.1    Yang, L.2    Tang, Q.3    Samdani, S.4    Zhang, G.5    Wang, J.Q.6
  • 50
    • 0030583640 scopus 로고    scopus 로고
    • MK801 prevents levodopa-induced motor response alterations in parkinsonian rats
    • C Marin S Papa TM Engber M Bonastre E Tolosa TN Chase 1996 MK801 prevents levodopa-induced motor response alterations in parkinsonian rats Brain Res 736 202 205
    • (1996) Brain Res , vol.736 , pp. 202-205
    • Marin, C.1    Papa, S.2    Engber, T.M.3    Bonastre, M.4    Tolosa, E.5    Chase, T.N.6
  • 51
    • 0034659603 scopus 로고    scopus 로고
    • Non-NMDA receptor-mediated mechanisms are involved in levodopa-induced motor response alterations in parkinsonian rats
    • C Marin A Jiménez M Bonastre TN Chase E Tolosa 2000 Non-NMDA receptor-mediated mechanisms are involved in levodopa-induced motor response alterations in parkinsonian rats Synapse 36 267 274
    • (2000) Synapse , vol.36 , pp. 267-274
    • Marin, C.1    Jiménez, A.2    Bonastre, M.3    Chase, T.N.4    Tolosa, E.5
  • 52
    • 0034860914 scopus 로고    scopus 로고
    • LY293558, an AMPA glutamate receptor antagonist prevents and reverses levodopa-induced motor fluctuations in parkinsonian rats
    • C Marin A Jiménez M Vila M Bonastre EC Hirsch Y Agid E Tolosa 2001 LY293558, an AMPA glutamate receptor antagonist prevents and reverses levodopa-induced motor fluctuations in parkinsonian rats Synapse 42 40 47
    • (2001) Synapse , vol.42 , pp. 40-47
    • Marin, C.1    Jiménez, A.2    Vila, M.3    Bonastre, M.4    Hirsch, E.C.5    Agid, Y.6    Tolosa, E.7
  • 53
    • 33646949657 scopus 로고    scopus 로고
    • Coadministration of entacapone with levodopa attenuates the severity of dyskinesias in hemiparkinsonian rats
    • C Marin E Aguilar JA Obeso 2006 Coadministration of entacapone with levodopa attenuates the severity of dyskinesias in hemiparkinsonian rats Mov Dis 21 646 653
    • (2006) Mov Dis , vol.21 , pp. 646-653
    • Marin, C.1    Aguilar, E.2    Obeso, J.A.3
  • 54
    • 30444460587 scopus 로고    scopus 로고
    • Motor complications in Parkinson's disease and the clinical significance of rotational behavior in the rat. Have we wasted our time?
    • C Marin MC Rodríguez-Oroz JA Obeso 2006 Motor complications in Parkinson's disease and the clinical significance of rotational behavior in the rat. Have we wasted our time? Exp Neurol 197 269 274
    • (2006) Exp Neurol , vol.197 , pp. 269-274
    • Marin, C.1    Rodríguez-Oroz, M.C.2    Obeso, J.A.3
  • 55
    • 0012667907 scopus 로고    scopus 로고
    • Modulation of the basal ganglia by metabotropic-glutamate receptors: Potential for novel therapeutics
    • MJ Marino JP Conn 2002 Modulation of the basal ganglia by metabotropic-glutamate receptors: potential for novel therapeutics Curr Drug Target CNS Neurol Dis 1 239 250
    • (2002) Curr Drug Target CNS Neurol Dis , vol.1 , pp. 239-250
    • Marino, M.J.1    Conn, J.P.2
  • 56
    • 34047186385 scopus 로고    scopus 로고
    • Antagonism of metabotropic glutamate receptor type 5 attenuates L-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease
    • F Mela M Marti A Dekundy W Danysz M Morari MA Cenci 2007 Antagonism of metabotropic glutamate receptor type 5 attenuates L-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease J Neurochem 101 483 497
    • (2007) J Neurochem , vol.101 , pp. 483-497
    • Mela, F.1    Marti, M.2    Dekundy, A.3    Danysz, W.4    Morari, M.5    Cenci, M.A.6
  • 59
    • 0033695441 scopus 로고    scopus 로고
    • Levodopa motor complications in Parkinson's disease
    • JA Obeso CW Olanow JG Nutt 2000 Levodopa motor complications in Parkinson's disease Trends Neurosci 23 Suppl 10 S2 S7
    • (2000) Trends Neurosci , vol.23 , Issue.SUPPL. 10
    • Obeso, J.A.1    Olanow, C.W.2    Nutt, J.G.3
  • 61
    • 0033550940 scopus 로고    scopus 로고
    • Effect of dopamine denervation and dopamine agonist administration on serine phosphorylation of striatal receptor subunits
    • Oh JD, Vaughan CL, Chase TN (1999) Effect of dopamine denervation and dopamine agonist administration on serine phosphorylation of striatal receptor subunits. Brain Res 821:433-442
    • (1999) Brain Res , vol.821 , pp. 433-442
    • Oh, J.D.1    Vaughan, C.L.2    Chase, T.N.3
  • 62
    • 0034868541 scopus 로고    scopus 로고
    • Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rat
    • K Ossowska J Konieczny S Wolfarth K Wieronska A Pilc 2001 Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rat Neuropharmacology 41 413 420
    • (2001) Neuropharmacology , vol.41 , pp. 413-420
    • Ossowska, K.1    Konieczny, J.2    Wolfarth, S.3    Wieronska, K.4    Pilc, A.5
  • 63
    • 0037144230 scopus 로고    scopus 로고
    • The striatum as a target for anti-rigor effects of an antagonist of mGLuR1, but not an agonist of groups II metabotropic glutamate receptors
    • K Ossowska J Konieczny A Pic S Wolfarth 2002 The striatum as a target for anti-rigor effects of an antagonist of mGLuR1, but not an agonist of groups II metabotropic glutamate receptors Brain Res 950 88 94
    • (2002) Brain Res , vol.950 , pp. 88-94
    • Ossowska, K.1    Konieczny, J.2    Pic, A.3    Wolfarth, S.4
  • 64
    • 0037448018 scopus 로고    scopus 로고
    • The striatopallidal pathway is involved in antiparkinsonian-like effects of the blockade of groups i metabotropic glutamate receptors in rats
    • K Ossowska J Wardas M Pietraszek J Koniwczny S Wolfarth 2003 The striatopallidal pathway is involved in antiparkinsonian-like effects of the blockade of groups I metabotropic glutamate receptors in rats Neurosci Lett 342 21 24
    • (2003) Neurosci Lett , vol.342 , pp. 21-24
    • Ossowska, K.1    Wardas, J.2    Pietraszek, M.3    Koniwczny, J.4    Wolfarth, S.5
  • 65
    • 0028046229 scopus 로고
    • Motor fluctuations in levodopa-treated parkinsonian rats: Relation to lesion extent and treatment duration
    • SM Papa TM Engber AM Kask TN Chase 1994 Motor fluctuations in levodopa-treated parkinsonian rats: relation to lesion extent and treatment duration Brain Res 662 69 74
    • (1994) Brain Res , vol.662 , pp. 69-74
    • Papa, S.M.1    Engber, T.M.2    Kask, A.M.3    Chase, T.N.4
  • 66
    • 29344434297 scopus 로고    scopus 로고
    • ERK phosphorylation an FosB expression are associated with L-Dopa-induced dyskinesia in hemiparkinsonian mice
    • N Pavon AB Martin A Mendialdua R Moratalla 2006 ERK phosphorylation an FosB expression are associated with L-Dopa-induced dyskinesia in hemiparkinsonian mice Biol Psychiatry 59 64 74
    • (2006) Biol Psychiatry , vol.59 , pp. 64-74
    • Pavon, N.1    Martin, A.B.2    Mendialdua, A.3    Moratalla, R.4
  • 67
    • 69549122874 scopus 로고
    • Academic New York
    • Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. Academic, New York
    • (1986)
    • Paxinos, G.1    Watson, C.2
  • 68
    • 18744387960 scopus 로고    scopus 로고
    • The AMPA receptor antagonist LY293558 reverses preproenkephalin mRNA overexpression in the striatum of 6-OHDA-lesioned rats treated with L-Dopa
    • C Perier C Marin M Bonastre E Tolosa EC Hirsch 2002 The AMPA receptor antagonist LY293558 reverses preproenkephalin mRNA overexpression in the striatum of 6-OHDA-lesioned rats treated with L-Dopa Eur J Neurosci 16 2236 2240
    • (2002) Eur J Neurosci , vol.16 , pp. 2236-2240
    • Perier, C.1    Marin, C.2    Bonastre, M.3    Tolosa, E.4    Hirsch, E.C.5
  • 69
    • 33644955961 scopus 로고    scopus 로고
    • Blockade of mGluR5 glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease
    • JM Phillips HA Lam LC Ackerson NT Maidment 2006 Blockade of mGluR5 glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease Eur J Neurosci 23 151 160
    • (2006) Eur J Neurosci , vol.23 , pp. 151-160
    • Phillips, J.M.1    Lam, H.A.2    Ackerson, L.C.3    Maidment, N.T.4
  • 71
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptor: Structure and functions
    • JP Pin R Duvoisin 1995 The metabotropic glutamate receptor: structure and functions Neuropharmacology 34 1 26
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 72
    • 0035137866 scopus 로고    scopus 로고
    • Functional coexpression of excitatory mGluR1 and mGluR5 on striatal cholinergic interneurons
    • A Pisani P Bonsi D Centonze G Bernardi P Calabresi 2001 Functional coexpression of excitatory mGluR1 and mGluR5 on striatal cholinergic interneurons Neuropharmacology 40 460 463
    • (2001) Neuropharmacology , vol.40 , pp. 460-463
    • Pisani, A.1    Bonsi, P.2    Centonze, D.3    Bernardi, G.4    Calabresi, P.5
  • 73
    • 0035959976 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 mediates the potentiation of N-Methyl-D-aspartate responses in medium spiny striatal neurons
    • A Pisani P Gubellini P Bonsi F Conquet B Picconi D Centonze G Bernardi P Calabresi 2001 Metabotropic glutamate receptor 5 mediates the potentiation of N-Methyl-D-aspartate responses in medium spiny striatal neurons Neuroscience 106 579 587
    • (2001) Neuroscience , vol.106 , pp. 579-587
    • Pisani, A.1    Gubellini, P.2    Bonsi, P.3    Conquet, F.4    Picconi, B.5    Centonze, D.6    Bernardi, G.7    Calabresi, P.8
  • 75
    • 0038517748 scopus 로고    scopus 로고
    • Targeting striatal cholinergic interneurons in Parkinson's disease: Focus on metabotropic glutamate receptors
    • A Pisani P Bonsi D Centonze P Gubellini G Bernardi P Calabresi 2003 Targeting striatal cholinergic interneurons in Parkinson's disease: focus on metabotropic glutamate receptors Neuropharmacology 45 45 56
    • (2003) Neuropharmacology , vol.45 , pp. 45-56
    • Pisani, A.1    Bonsi, P.2    Centonze, D.3    Gubellini, P.4    Bernardi, G.5    Calabresi, P.6
  • 76
    • 0036899273 scopus 로고    scopus 로고
    • Homer 1 a gene expression modulation by antipsychotic drugs: Involvement of the glutamate metabotropic system and effects of D-Cycloserine
    • D Polese AA de Serpia A Ambesi-Impiombato G Muscettola A de Bartolomeis 2002 Homer 1 a gene expression modulation by antipsychotic drugs: Involvement of the glutamate metabotropic system and effects of D-Cycloserine Neuropsychopharmacology 27 906 913
    • (2002) Neuropsychopharmacology , vol.27 , pp. 906-913
    • Polese, D.1    De Serpia, A.A.2    Ambesi-Impiombato, A.3    Muscettola, G.4    De Bartolomeis, A.5
  • 77
    • 0034451725 scopus 로고    scopus 로고
    • Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: Implications for treatment of Parkinson's disease and related disorders
    • ST Rouse MJ Marino SR Bradley H Awad M Wittmann PJ Conn 2000 Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: implications for treatment of Parkinson's disease and related disorders Pharmacol Ther 88 427 435
    • (2000) Pharmacol Ther , vol.88 , pp. 427-435
    • Rouse, S.T.1    Marino, M.J.2    Bradley, S.R.3    Awad, H.4    Wittmann, M.5    Conn, P.J.6
  • 79
    • 0032834028 scopus 로고    scopus 로고
    • Pharmacological agents acting at subtypes of metabotropic glutamate receptors
    • DD Schoepp DE Jane JA Monn 1999 Pharmacological agents acting at subtypes of metabotropic glutamate receptors Neuropharmacology 38 1431 1476
    • (1999) Neuropharmacology , vol.38 , pp. 1431-1476
    • Schoepp, D.D.1    Jane, D.E.2    Monn, J.A.3
  • 80
    • 27944469585 scopus 로고    scopus 로고
    • Coordinated and spatial upregulation of arc in striatonigral neurons correlates with L-DOPA-induced behavioral sensitization in dyskinetic rats
    • V Sgambato-Faure V Buggia F Gilbert D Levesque AL Benabid F Berger 2005 Coordinated and spatial upregulation of arc in striatonigral neurons correlates with L-DOPA-induced behavioral sensitization in dyskinetic rats J Neuropathol Exp Neurol 64 936 947
    • (2005) J Neuropathol Exp Neurol , vol.64 , pp. 936-947
    • Sgambato-Faure, V.1    Buggia, V.2    Gilbert, F.3    Levesque, D.4    Benabid, A.L.5    Berger, F.6
  • 81
    • 0033909559 scopus 로고    scopus 로고
    • Gaba(B) and group i metabotropic glutamate receptors in the striatopallidal complex in primates
    • Y Smith A Charara JE Hanson M Paquet AI Levey 2000 Gaba(B) and group I metabotropic glutamate receptors in the striatopallidal complex in primates J Anat 196 555 576
    • (2000) J Anat , vol.196 , pp. 555-576
    • Smith, Y.1    Charara, A.2    Hanson, J.E.3    Paquet, M.4    Levey, A.I.5
  • 82
    • 0034693328 scopus 로고    scopus 로고
    • Effects of the prototypical mGluR5 receptor antagonist 2-methyl-6-(phenylethylnyl)-pyridine on rotarod, locomotor activity and rotational response in unilateral 6-OHDA-lesioned rats
    • WPJM Spooren F Gasparini R Bergmann R Kuhn 2000 Effects of the prototypical mGluR5 receptor antagonist 2-methyl-6-(phenylethylnyl)-pyridine on rotarod, locomotor activity and rotational response in unilateral 6-OHDA-lesioned rats Eur J Pharmacol 406 403 410
    • (2000) Eur J Pharmacol , vol.406 , pp. 403-410
    • Wpjm, S.1    Gasparini, F.2    Bergmann, R.3    Kuhn, R.4
  • 83
    • 0035397917 scopus 로고    scopus 로고
    • Novel allosteric antagonists shed light on mGluR5 receptors and CNS disorders
    • WP Spooren F Gasparini TE Salt R Kuhn 2001 Novel allosteric antagonists shed light on mGluR5 receptors and CNS disorders Trends Pharmacol Sci 2 331 337
    • (2001) Trends Pharmacol Sci , vol.2 , pp. 331-337
    • Spooren, W.P.1    Gasparini, F.2    Salt, T.E.3    Kuhn, R.4
  • 84
    • 0035889975 scopus 로고    scopus 로고
    • Repeated cocaine administration attenuates group i metabotropic glutamate receptor-mediated glutamate release and behavioural activation: A potential role for Homer
    • CJ Swanson DA Baker D Carson PF Worley PW Kalivas 2001 Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioural activation: a potential role for Homer J Neurosci 21 9043 9052
    • (2001) J Neurosci , vol.21 , pp. 9043-9052
    • Swanson, C.J.1    Baker, D.A.2    Carson, D.3    Worley, P.F.4    Kalivas, P.W.5
  • 86
    • 31444436515 scopus 로고    scopus 로고
    • Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family
    • A Tappe R Kuner 2006 Regulation of motor performance and striatal function by synaptic scaffolding proteins of the Homer1 family PNAS 103 774 779
    • (2006) PNAS , vol.103 , pp. 774-779
    • Tappe, A.1    Kuner, R.2
  • 87
    • 0028270378 scopus 로고
    • Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat
    • CM Testa DG Standaert AB Young JB Penney 1994 Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat J Neurosci 14 3005 3018
    • (1994) J Neurosci , vol.14 , pp. 3005-3018
    • Testa, C.M.1    Standaert, D.G.2    Young, A.B.3    Penney, J.B.4
  • 89
    • 0031930027 scopus 로고    scopus 로고
    • Immunohistochemcial localization of metabotropic glutamate receptors mGluR1 and mGluR2/3 in the rat basal ganglia
    • CM Testa IK Friberg SW Weiss DG Standaert 1998 Immunohistochemcial localization of metabotropic glutamate receptors mGluR1 and mGluR2/3 in the rat basal ganglia J Comp Neurol 390 5 19
    • (1998) J Comp Neurol , vol.390 , pp. 5-19
    • Testa, C.M.1    Friberg, I.K.2    Weiss, S.W.3    Standaert, D.G.4
  • 90
    • 0036316339 scopus 로고    scopus 로고
    • Modulation of synaptic signaling complexes by Homer proteins
    • U Thomas 2002 Modulation of synaptic signaling complexes by Homer proteins J Neurochem 81 40 413
    • (2002) J Neurochem , vol.81 , pp. 40-413
    • Thomas, U.1
  • 91
    • 0032995869 scopus 로고    scopus 로고
    • Systemic administration of NMDA and AMPA receptor antagonists reverses the neurochemical changes induced by nigrostriatal denervation in basal ganglia
    • M Vila C Marin M Ruberg A Jiménez R Raisman-Vozari Y Agid E Tolosa E Hirsch 1999 Systemic administration of NMDA and AMPA receptor antagonists reverses the neurochemical changes induced by nigrostriatal denervation in basal ganglia J Neurochem 73 344 352
    • (1999) J Neurochem , vol.73 , pp. 344-352
    • Vila, M.1    Marin, C.2    Ruberg, M.3    Jiménez, A.4    Raisman-Vozari, R.5    Agid, Y.6    Tolosa, E.7    Hirsch, E.8
  • 93
    • 0036070538 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of Parkinson's disease: Relation to motor and cellular parameters of nigrostriatal function
    • C Winkler D Kirik A Bjorklund MA Cenci 2002 L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of Parkinson's disease: relation to motor and cellular parameters of nigrostriatal function Neurobiol Dis 10 165 186
    • (2002) Neurobiol Dis , vol.10 , pp. 165-186
    • Winkler, C.1    Kirik, D.2    Bjorklund, A.3    Cenci, M.A.4
  • 95
    • 33845967507 scopus 로고    scopus 로고
    • 2 receptor agonist, induces gene expression of Homer 1a in rat striatum and nucleus accumbens
    • DOI 10.1016/j.brainres.2006.11.011, PII S0006899306032677
    • H Yamada T Kuroki T Nakahara K Hashimoto T Tsutsumi M Hirano H Maeda 2007 The dopamine D1 receptor agonist but not the D2 receptor agonist, induces gene expression of Homer 1a in rat striatum and nucleus accumbens Brain Res 1131 88 96 (Pubitemid 46053909)
    • (2007) Brain Research , vol.1131 , Issue.1 , pp. 88-96
    • Yamada, H.1    Kuroki, T.2    Nakahara, T.3    Hashimoto, K.4    Tsutsumi, T.5    Hirano, M.6    Maeda, H.7
  • 96
    • 17044416853 scopus 로고    scopus 로고
    • Methykphenidate (Ritalin) induces Homer 1a and zif268 expression in specific corticostriatal circuits
    • M Yano H Steiner 2005 Methykphenidate (Ritalin) induces Homer 1a and zif268 expression in specific corticostriatal circuits Neuroscience 132 855 865
    • (2005) Neuroscience , vol.132 , pp. 855-865
    • Yano, M.1    Steiner, H.2
  • 97
    • 33646524922 scopus 로고    scopus 로고
    • Inhibition of methylphenidate-induced gene expression in the striatum by local blockade of D1 receptors: Interhemispheric effects
    • M Yano JA Beverley H Steiner 2006 Inhibition of methylphenidate-induced gene expression in the striatum by local blockade of D1 receptors: interhemispheric effects Neuroscience 140 699 709
    • (2006) Neuroscience , vol.140 , pp. 699-709
    • Yano, M.1    Beverley, J.A.2    Steiner, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.