Identification of surrogate agonists and antagonists for orphan g-protein-coupled receptor GPR139

Journal of Biomolecular Screening

Volumn 14, Issue 7, 2009, Pages 789-797

  Hu, Liaoyuan A ^a   Tang, Pauline M ^a   Eslahi, Nima K ^a   Zhou, Tian ^a   Barbosa, Joseph ^a   Liu, Qingyun ^a  

^a LEXICON PHARMACEUTICALS INC   (United States)

Author keywords

Agonist and antagonist; GPR139; HTS; Orphan GPCR

Indexed keywords

CYCLIC AMP; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; ISOPRENALINE; PROTEIN GPR139; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LOCOMOTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SCREENING; SIGNAL TRANSDUCTION;

CELL LINE; CLONE CELLS; DRUG EVALUATION, PRECLINICAL; HUMANS; NERVE TISSUE PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; TRANSFECTION;

EID: 69549087944     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057109335744     Document Type: Article

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