Vascular defects in gain-of-function fps/fes transgenic mice correlate with PDGF- and VEGF-induced activation of mutant Fps/Fes kinase in endothelial cells

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 5, 2004, Pages 820-832

  Sangrar, W ^a,b   Mewburn, J D ^a   Vincent, S G ^b   Fisher, J T ^b   Greer, Peter A ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

Angiogenesis; fps fes; Platelet derived growth factor; Vascular endothelial growth factor

Indexed keywords

ANGIOPOIETIN 1; GENE PRODUCT; HISTAMINE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE FES; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BLOOD VESSEL DIAMETER; BLOOD VESSEL PERMEABILITY; CELL LINE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MODEL; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC CODE; GENETIC LINE; GENETIC VARIABILITY; MICROSCOPY; MOUSE; MYRISTYLATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTO ONCOGENE; REGULATORY MECHANISM; SENSITIZATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; VARICOSIS; VASCULAR DISEASE; VASCULARIZATION;

ANIMALS; BLOOD VESSELS; BRAIN; CELL LINE; CORONARY VESSELS; EMBRYO; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HEMODYNAMIC PROCESSES; HUMANS; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; PLATELET-DERIVED GROWTH FACTOR; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 6944234659     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.00654.x     Document Type: Article

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