Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor II signaling

Endocrinology

Volumn 150, Issue 9, 2009, Pages 4366-4375

  White, Yvonne A R ^a   Kyle, Joshua T ^a   Wood, Antony W ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b THR 933 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN LIKE GROWTH FACTOR 2A; INSULIN LIKE GROWTH FACTOR 2B; OLIGONUCLEOTIDE; SOMATOMEDIN B; UNCLASSIFIED DRUG;

ARTICLE; BRAIN DEVELOPMENT; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO SEGMENTATION; FOREBRAIN; GENE EXPRESSION; KIDNEY DEVELOPMENT; NEURULATION; NONHUMAN; NOTOCHORD; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; ZEBRA FISH;

ANIMALS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULIN-LIKE GROWTH FACTOR II; SIGNAL TRANSDUCTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 69249085415     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0356     Document Type: Article

References (62)

1. Wood AW, Duan C, Bern HA 2005 Insulin-like growth factor signaling in fish. Int Rev Cytol 243:215-285
2. Dupont J, Holzenberger M 2003 Biology of insulin-like growth factors in development. Birth Defects Res C Embryo Today 69:257-271
3. Hwa V, Oh Y, Rosenfeld RG 1999 The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev 20:761-787
4. Butler AA, Yakar S, Gewolb IH, Karas M, Okubo Y, LeRoith D 1998 Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology. Comp Biochem Physiol B Biochem Mol Biol 121:19-26
5. Reinecke M, Collet C 1998 The phylogeny of the insulin-like growth factors. Int Rev Cytol 183:1-94
6. Binoux M 1995 The IGF system in metabolism regulation. Diabetes Metab 21:330-337
7. Thissen JP, Ketelslegers JM, Underwood LE 1994 Nutritional regulation of the insulin-like growth factors. Endocr Rev 15:80-101
8. Le Roith D, Bondy C, Yakar S, Liu JL, Butler A 2001 The somatomedin hypothesis: 2001. Endocr Rev 22:53-74
9. Sullivan KA, Kim B, Feldman EL 2008 Insulin-like growth factors in the peripheral nervous system. Endocrinology 149:5963-5971
10. Fiedler J, Brill C, Blum WF, Brenner RE 2006 IGF-I and IGF-II stimulate directed cell migration of bone-marrow-derived human mesenchymal progenitor cells. Biochem Biophys Res Commun 345:1177-1183
11. Ciampolillo A, De Tullio C, Giorgino F 2005 The IGF-I/IGF-I receptor pathway: implications in the pathophysiology of thyroid cancer. Curr Med Chem 12:2881-2891
12. Ruberte J, Ayuso E, Navarro M, Carretero A, Nacher V, Haurigot V, George M, Llombart C, Casellas A, Costa C, Bosch A, Bosch F 2004 Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease. J Clin Invest 113:1149-1157
13. LeRoith D, Roberts Jr CT 2003 The insulin-like growth factor system and cancer. Cancer Lett 195:127-137
14. Chao W, D'Amore PA 2008 IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev 19:111-120
15. Coan PM, Fowden AL, Constancia M, Ferguson-Smith AC, Burton GJ, Sibley CP 2008 Disproportional effects of Igf2 knockout on placental morphology and diffusional exchange characteristics in the mouse. J Physiol 586:5023-5032
16. Sibley CP, Coan PM, Ferguson-Smith AC, Dean W, Hughes J, Smith P, Reik W, Burton GJ, Fowden AL, Constância M 2004 Placental-specific insulin-like growth factor 2 (IGF2) regulates the diffusional exchange characteristics of the mouse placenta. Proc Natl Acad Sci USA 101:8204-8208
17. Murphy R, Baptista J, Holly J, Umpleby AM, Ellard S, Harries LW, Crolla J, Cundy T, Hattersley AT 2008 Severe intrauterine growth retardation and atypical diabetes associated with a translocation breakpoint disrupting regulation of the insulin-like growth factor 2 gene. J Clin Endocrinol Metab 93:4373-4380
18. Tapanainen PJ, Bang P, Wilson K, Unterman TG, Vreman HJ, Rosenfeld RG 1994 Maternal hypoxia as a model for intrauterine growth retardation: effects on insulin-like growth factors and their binding proteins. Pediatr Res 36:152-158
19. Bentov I, Werner H 2004 IGF, IGF receptor and overgrowth syndromes. Pediatr Endocrinol Rev 1:352-360
20. D'Ercole AJ 1999 Mechanisms of in utero overgrowth. Acta Paediatr Suppl 88:31-36
21. Eggenschwiler J, Ludwig T, Fisher P, Leighton PA, Tilghman SM, Efstratiadis A 1997 Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. Genes Dev 11:3128-3142
22. Ward A 1997 Beck-Wiedemann syndrome and Wilms' tumour. Mol Hum Reprod 3:157-168
23. Gicquel C, Le Bouc Y 2006 Hormonal regulation of fetal growth. Horm Res 65(Suppl 3):28-33
24. Lee J, Pintar J, Efstratiadis A 1990 Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesis. Development 110:151-159
25. Burns JL, Hassan AB 2001 Cell survival and proliferation are modified by insulin-like growth factor 2 between days 9 and 10 of mouse gestation. Development 128:3819-3830
26. Pera EM, Wessely O, Li SY, De Robertis EM 2001 Neural and head induction by insulin-like growth factor signals. Dev Cell 1:655-665
27. Pera EM, Ikeda A, Eivers E, De Robertis EM 2003 Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev 17:3023-3028
28. Richard-Parpaillon L, Héligon C, Chesnel F, Boujard D, Philpott A 2002 The IGF pathway regulates head formation by inhibiting Wnt signaling in Xenopus. Dev Biol 244:407-417
29. Eivers E, McCarthy K, Glynn C, Nolan CM, Byrnes L 2004 Insulin-like growth factor (IGF) signalling is required for early dorso-anterior development of the zebrafish embryo. Int J Dev Biol 48:1131-1140
30. Allan GJ, Zannoni A, McKinnell I, Otto WR, Holzenberger M, Flint DJ, Patel K 2003 Major components of the insulin-like growth factor axis are expressed early in chicken embryogenesis, with IGF binding protein (IGFBP)-5 expression subject to regulation by Sonic Hedgehog. Anat Embryol (Berl) 207:73-84
31. Sang X, Curran MS, Wood AW 2008 Paracrine insulin-like growth factor signaling influences primordial germ cell migration: in vivo evidence from the zebrafish model. Endocrinology 149:5035-5042
32. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF 1995 Stages of embryonic development of the zebrafish. Dev Dyn 203:253-310
33. Schlueter PJ, Sang X, Duan C, Wood AW 2007 Insulin-like growth factor receptor 1b is required for zebrafish primordial germ cell migration and survival. Dev Biol 305:377-387
34. Draper BW, Morcos PA, Kimmel CB 2001 Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30:154-156
35. Hawkins TA, Cavodeassi F, Erdélyi F, Szabó G, Lele Z 2008 The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish. BMC Dev Biol 8:42
36. Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC 2007 p53 activation by knockdown technologies. PLoS Genet 3:e78
37. Holley SA, Nüsslein-Volhard C 2000 Somitogenesis in zebrafish. Curr Top Dev Biol 47:247-277
38. Odenthal J, van Eeden FJ, Haffter P, Ingham PW, Nüsslein-Volhard C 2000 Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Dev Biol 219:350-363
39. van Eeden FJ, Granato M, Schach U, Brand M, Furutani-Seiki M, Haffter P, Hammerschmidt M, Heisenberg CP, Jiang YJ, Kane DA, Kelsh RN, Mullins MC, Odenthal J, Warga RM, Allende ML,Weinberg ES, Nüsslein-Volhard C 1996 Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123:153-164
40. Drummond IA, Majumdar A, Hentschel H, Elger M, Solnica-Krezel L, Schier AF, Neuhauss SC, Stemple DL, Zwartkruis F, Rangini Z, Driever W, Fishman MC 1998 Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development 125:4655-4667
41. Grandjean V, Smith J, Schofield PN, Ferguson-Smith AC 2000 Increased IGF-II protein affects p57kip2 expression in vivo and in vitro: implications for Beckwith-Wiedemann syndrome. Proc Natl Acad Sci USA 97:5279-5284
42. Baker J, Liu JP, Robertson EJ, Efstratiadis A 1993 Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75:73-82
43. Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A 1993 Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-1) and type 1 IGF receptor (IGF-1R). Cell 75:59-72
44. Lawton BR, Sevigny L, Obergfell C, Reznick D, O'Neill RJ, O'Neill MJ 2005 Allelic expression of IGF2 in live-bearing, matrotrophic fishes. Dev Genes Evol 215:207-212
45. O'Neill MJ, Lawton BR, Mateos M, Carone DM, Ferreri GC, Hrbek T, Meredith RW, Reznick DN, O'Neill RJ 2007 Ancient and continuing Darwinian selection on insulin-like growth factor II in placental fishes. Proc Natl Acad Sci USA 104:12404-12409
46. Schlueter PJ, Royer T, Farah MH, Laser B, Chan SJ, Steiner DF, Duan C 2006 Gene duplication and functional divergence of the zebrafish insulin-like growth factor 1 receptors. FASEB J 20:1230-1232
47. Schlueter PJ, Peng G, Westerfield M, Duan C 2007 Insulin-like growth factor signaling regulates zebrafish embryonic growth and development by promoting cell survival and cell cycle progression. Cell Death Differ 14:1095-1105
48. Tanabe Y, Jessell TM 1996 Diversity and pattern in the developing spinal cord. Science 274:1115-1123
49. Litingtung Y, Chiang C 2000 Control of Shh activity and signaling in the neural tube. Dev Dyn 219:143-154
50. Odenthal J, Haffter P, Vogelsang E, Brand M, van Eeden FJ, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg CP, Jiang YJ, Kane DA, Kelsh RN, Mullins MC, Warga RM, Allende ML, Weinberg ES, Nüsslein-Volhard C 1996 Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development 123:103-115
51. Tanabe Y, Roelink H, Jessell TM 1995 Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation. Curr Biol 5:651-658
52. Roelink H, Augsburger A, Heemskerk J, Korzh V, Norlin S, Ruiz i Altaba A, Tanabe Y, Placzek M, Edlund T, Jessell TM, Dodd J 1994 Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76:761-775
53. Fernandes M, Hébert JM 2008 The ups and downs of holoprosencephaly: dorsal versus ventral patterning forces. Clin Genet 73:413-423
54. Cordero DR, Bendavid C, Shanske AL, Haddad BR, Muenke M 2008 Holoprosencephaly-Polydactyly syndrome: in search of an etiology. Eur J Med Genet 51:106-112
55. Shiota K, Yamada S, Komada M, Ishibashi M 2007 Embryogenesis of holoprosencephaly. Am J Med Genet A 143:3079-3087
56. Hahn H, Wojnowski L, Specht K, Kappler R, Calzada-Wack J, Potter D, Zimmer A, Muller U, Samson E, Quintanilla-Martinez L 2000 Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J Biol Chem 275:28341-28344
57. Hartmann W, Koch A, Brune H, Waha A, Schuller U, Dani I, Denkhaus D, Langmann W, Bode U, Wiestler OD, Schilling K, Pietsch T 2005 Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. Am J Pathol 166:1153-1162
58. Rao G, Pedone CA, Del Valle L, Reiss K, Holland EC, Fults DW 2004 Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice. Oncogene 23:6156-6162
59. Parathath SR, Mainwaring LA, Fernandez LA, Campbell DO, Kenney AM 2008 Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors. Development 135:3291-3300
60. Kappler R, Calzada-Wack J, Schnitzbauer U, Koleva M, Herwig A, Piontek G, Graedler F, Adamski J, Heinzmann U, Schlegel J, Hemmerlein B, Quintanilla-Martinez L, Hahn H 2003 Molecular characterization of Patched-associated rhabdomyosarcoma. J Pathol 200:348-356
61. Russo VC, Gluckman PD, Feldman EL, Werther GA 2005 The insulin-like growth factor system and its pleiotropic functions in brain. Endocr Rev 26:916-943
62. Villalpando I, López-Olmos V 2003 Insulin-like growth factor I (IGF-I) regulates endocrine activity of the embryonic testis in the mouse. J Steroid Biochem Mol Biol 86:151-158