메뉴 건너뛰기




Volumn 39, Issue 7, 2009, Pages 1765-1773

DC-induced CD8+ T-cell response is inhibited by MHC class II-dependent DX5+CD4+ Treg

Author keywords

DC; Immune regulation; MHC; T cells

Indexed keywords

DENDRITIC CELL VACCINE; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN; TRANSCRIPTION FACTOR FOXP3;

EID: 69249084062     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838842     Document Type: Article
Times cited : (8)

References (43)
  • 1
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 2
    • 0020077493 scopus 로고
    • Helper activity is required for the in vivo generation of cytotoxic T lymphocytes
    • Keene, J. A. and Forman, J., Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J. Exp. Med. 1982. 155: 768-782.
    • (1982) J. Exp. Med , vol.155 , pp. 768-782
    • Keene, J.A.1    Forman, J.2
  • 4
    • 0026717868 scopus 로고
    • A fail-safe mechanism for maintaining self-tolerance
    • Guerder, S. and Matzinger, P., A fail-safe mechanism for maintaining self-tolerance. J. Exp. Med. 1992. 176: 553-564.
    • (1992) J. Exp. Med , vol.176 , pp. 553-564
    • Guerder, S.1    Matzinger, P.2
  • 7
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock, D. J. and Shen, H., Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003. 300: 337-339.
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 8
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J. C. and Bevan, M. J., Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003. 300: 339-342.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 9
    • 0032482474 scopus 로고    scopus 로고
    • T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
    • Schoenberger, S. P., Toes, R. E., van der Voort, E. I., Offringa, R. and Melief, C. J., T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998. 393: 480-483.
    • (1998) Nature , vol.393 , pp. 480-483
    • Schoenberger, S.P.1    Toes, R.E.2    van der Voort, E.I.3    Offringa, R.4    Melief, C.J.5
  • 10
    • 0032984496 scopus 로고    scopus 로고
    • CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy
    • Diehl, L., den Boer, A. T., Schoenberger, S. P., van der Voort, E. I., Schumacher, T. N., Melief, C. J., Offringa, R. and Toes, R. E., CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nat. Med. 1999. 5: 774-779.
    • (1999) Nat. Med , vol.5 , pp. 774-779
    • Diehl, L.1    den Boer, A.T.2    Schoenberger, S.P.3    van der Voort, E.I.4    Schumacher, T.N.5    Melief, C.J.6    Offringa, R.7    Toes, R.E.8
  • 11
    • 0029812593 scopus 로고    scopus 로고
    • Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
    • Cella, M., Scheidegger, D., Palmer-Lehmann, K., Lane, P., Lanzavecchia, A. and Alber, G., Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 1996. 184: 747-752.
    • (1996) J. Exp. Med , vol.184 , pp. 747-752
    • Cella, M.1    Scheidegger, D.2    Palmer-Lehmann, K.3    Lane, P.4    Lanzavecchia, A.5    Alber, G.6
  • 12
    • 18544402305 scopus 로고    scopus 로고
    • Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli
    • Schuurhuis, D. H., Laban, S., Toes, R. E., Ricciardi-Castagnoli, P., Kleijmeer, M. J., van der Voort, E. I., Rea, D. et al., Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli. J. Exp. Med. 2000. 192: 145-150.
    • (2000) J. Exp. Med , vol.192 , pp. 145-150
    • Schuurhuis, D.H.1    Laban, S.2    Toes, R.E.3    Ricciardi-Castagnoli, P.4    Kleijmeer, M.J.5    van der Voort, E.I.6    Rea, D.7
  • 13
    • 0035421654 scopus 로고    scopus 로고
    • + T cell activation by CD4+CD25+ immunoregulatory cells
    • + T cell activation by CD4+CD25+ immunoregulatory cells. J. Immunol. 2001. 167: 1137-1140.
    • (2001) J. Immunol , vol.167 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 14
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller, R. P., van Duivenvoorde, L. M., van Elsas, A., Schumacher, T. N., Wildenberg, M. E., Allison, J. P., Toes, R. E. et al., Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 2001. 194: 823-832.
    • (2001) J. Exp. Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5    Allison, J.P.6    Toes, R.E.7
  • 15
    • 20044363610 scopus 로고    scopus 로고
    • CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
    • Antony, P. A., Piccirillo, C. A., Akpinarli, A., Finkelstein, S. E., Speiss, P. J., Surman, D. R., Palmer, D. C. et al., CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J. Immunol. 2005. 174: 2591-2601.
    • (2005) J. Immunol , vol.174 , pp. 2591-2601
    • Antony, P.A.1    Piccirillo, C.A.2    Akpinarli, A.3    Finkelstein, S.E.4    Speiss, P.J.5    Surman, D.R.6    Palmer, D.C.7
  • 16
    • 34247554229 scopus 로고    scopus 로고
    • Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response
    • den Haan, J. M., Kraal, G. and Bevan, M. J., Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response. J. Immunol. 2007. 178: 5429-5433.
    • (2007) J. Immunol , vol.178 , pp. 5429-5433
    • den Haan, J.M.1    Kraal, G.2    Bevan, M.J.3
  • 17
    • 0035198718 scopus 로고    scopus 로고
    • Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes
    • Gonzalez, A., Andre-Schmutz, I., Carnaud, C., Mathis, D. and Benoist, C., Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes. Nat. Immunol. 2001. 2: 1117-1125.
    • (2001) Nat. Immunol , vol.2 , pp. 1117-1125
    • Gonzalez, A.1    Andre-Schmutz, I.2    Carnaud, C.3    Mathis, D.4    Benoist, C.5
  • 18
    • 0034305809 scopus 로고    scopus 로고
    • Kinetics of dendritic cell activation: Impact on priming of TH1, TH2 and nonpolarized T cells
    • Langenkamp, A., Messi, M., Lanzavecchia, A. and Sallusto, F., Kinetics of dendritic cell activation: Impact on priming of TH1, TH2 and nonpolarized T cells. Nat. Immunol. 2000. 1: 311-316.
    • (2000) Nat. Immunol , vol.1 , pp. 311-316
    • Langenkamp, A.1    Messi, M.2    Lanzavecchia, A.3    Sallusto, F.4
  • 20
    • 33748504567 scopus 로고    scopus 로고
    • Immature dendritic cells suppress collagen-induced arthritis by in vivo expansion of CD49b+ regulatory T cells
    • Charbonnier, L. M., van Duivenvoorde, L. M., Apparailly, F., Cantos, C., Han,W. G., Noel, D., Duperray, C. et al., Immature dendritic cells suppress collagen-induced arthritis by in vivo expansion of CD49b+ regulatory T cells. J. Immunol. 2006. 177: 3806-3813.
    • (2006) J. Immunol , vol.177 , pp. 3806-3813
    • Charbonnier, L.M.1    van Duivenvoorde, L.M.2    Apparailly, F.3    Cantos, C.4    Han, W.G.5    Noel, D.6    Duperray, C.7
  • 21
    • 0031735230 scopus 로고    scopus 로고
    • Intracellular IFN-gamma expression in natural killer cells precedes lung CD8+ T cell recruitment during respiratory syncytial virus infection
    • Hussell, T. and Openshaw, P. J., Intracellular IFN-gamma expression in natural killer cells precedes lung CD8+ T cell recruitment during respiratory syncytial virus infection. J. Gen. Virol. 1998. 79: 2593-2601.
    • (1998) J. Gen. Virol , vol.79 , pp. 2593-2601
    • Hussell, T.1    Openshaw, P.J.2
  • 22
    • 34548730876 scopus 로고    scopus 로고
    • Parallel expansion of human virus-specific Foxp3- effector memory and de novo-generated Foxp3+ regulatory CD8+ T cells upon antigen recognition in vitro
    • Billerbeck, E., Blum, H. E. and Thimme, R., Parallel expansion of human virus-specific Foxp3- effector memory and de novo-generated Foxp3+ regulatory CD8+ T cells upon antigen recognition in vitro. J. Immunol. 2007. 179: 1039-1048.
    • (2007) J. Immunol , vol.179 , pp. 1039-1048
    • Billerbeck, E.1    Blum, H.E.2    Thimme, R.3
  • 23
    • 34249944837 scopus 로고    scopus 로고
    • Joosten, S. A., van Meijgaarden, K. E., Savage, N. D., de Boer, T., Triebel, F., van der, W. A., deHeer, E. et al., Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4. Proc. Natl. Acad. Sci. USA 2007. 104: 8029-8034.
    • Joosten, S. A., van Meijgaarden, K. E., Savage, N. D., de Boer, T., Triebel, F., van der, W. A., deHeer, E. et al., Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4. Proc. Natl. Acad. Sci. USA 2007. 104: 8029-8034.
  • 25
    • 43649096023 scopus 로고    scopus 로고
    • Generation of highly suppressive adaptive CD8(+)CD25(+)FOXp3(+) regulatory T cells by continuous antigen stimulation
    • Mahic, M., Henjum, K., Yaqub, S., Bjornbeth, B.A., Torgersen, K.M., Tasken, K. and Aandahl, E. M., Generation of highly suppressive adaptive CD8(+)CD25(+)FOXp3(+) regulatory T cells by continuous antigen stimulation. Eur. J. Immunol. 2008. 38: 640-646.
    • (2008) Eur. J. Immunol , vol.38 , pp. 640-646
    • Mahic, M.1    Henjum, K.2    Yaqub, S.3    Bjornbeth, B.A.4    Torgersen, K.M.5    Tasken, K.6    Aandahl, E.M.7
  • 26
    • 36849010574 scopus 로고    scopus 로고
    • The role of CD8+CD28 regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand
    • Ben David, H., Sharabi, A., Dayan, M., Sela, M. and Mozes, E., The role of CD8+CD28 regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand. Proc. Natl. Acad. Sci. USA 2007. 104: 17459-17464.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 17459-17464
    • Ben David, H.1    Sharabi, A.2    Dayan, M.3    Sela, M.4    Mozes, E.5
  • 27
    • 41849087279 scopus 로고    scopus 로고
    • Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8(+) regulatory T cells
    • Fan, T. M., Kranz, D. M., Flavell, R. A. and Roy, E. J., Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8(+) regulatory T cells. Mol. Immunol. 2008. 45: 2937-2950.
    • (2008) Mol. Immunol , vol.45 , pp. 2937-2950
    • Fan, T.M.1    Kranz, D.M.2    Flavell, R.A.3    Roy, E.J.4
  • 28
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
    • Celluzzi, C. M., Mayordomo, J. I., Storkus, W. J., Lotze, M. T. and Falo, L. D., Jr., Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J. Exp. Med. 1996. 183: 283-287.
    • (1996) J. Exp. Med , vol.183 , pp. 283-287
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo Jr., L.D.5
  • 29
    • 0031113954 scopus 로고    scopus 로고
    • Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL
    • Brossart, P., Goldrath, A.W., Butz, E. A., Martin, S. and Bevan, M. J., Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL. J. Immunol. 1997. 158: 3270-3276.
    • (1997) J. Immunol , vol.158 , pp. 3270-3276
    • Brossart, P.1    Goldrath, A.W.2    Butz, E.A.3    Martin, S.4    Bevan, M.J.5
  • 30
    • 3142642827 scopus 로고    scopus 로고
    • Protection of mice against Friend retrovirus infection by vaccination with antigen-loaded, spleen-derived dendritic cells
    • Reuter, T., Heldmann, M., Schimmer, S., Schepers, K. and Dittmer, U., Protection of mice against Friend retrovirus infection by vaccination with antigen-loaded, spleen-derived dendritic cells. Vaccine 2004. 22: 2686-2689.
    • (2004) Vaccine , vol.22 , pp. 2686-2689
    • Reuter, T.1    Heldmann, M.2    Schimmer, S.3    Schepers, K.4    Dittmer, U.5
  • 31
    • 23844480879 scopus 로고    scopus 로고
    • Dendritic cells transduced with tumor-associated antigen gene elicit potent therapeutic antitumor immunity: Comparison with immunodominant peptide-pulsed DCs
    • Nakamura, M., Iwahashi, M., Nakamori, M., Ueda, K., Ojima, T., Naka, T., Ishida, K., and Yamaue, H., Dendritic cells transduced with tumor-associated antigen gene elicit potent therapeutic antitumor immunity: Comparison with immunodominant peptide-pulsed DCs. Oncology 2005. 68: 163-170.
    • (2005) Oncology , vol.68 , pp. 163-170
    • Nakamura, M.1    Iwahashi, M.2    Nakamori, M.3    Ueda, K.4    Ojima, T.5    Naka, T.6    Ishida, K.7    Yamaue, H.8
  • 32
    • 0030028770 scopus 로고    scopus 로고
    • Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo
    • Paglia, P., Chiodoni, C., Rodolfo, M. and Colombo, M. P., Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. J. Exp. Med. 1996. 183: 317-322.
    • (1996) J. Exp. Med , vol.183 , pp. 317-322
    • Paglia, P.1    Chiodoni, C.2    Rodolfo, M.3    Colombo, M.P.4
  • 33
    • 8544249166 scopus 로고    scopus 로고
    • Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines
    • Ito, F., Li, Q., Shreiner, A. B., Okuyama, R., Jure-Kunkel, M. N., Teitz-Tennenbaum, S. and Chang, A. E., Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines. Cancer Res. 2004. 64: 8411-8419.
    • (2004) Cancer Res , vol.64 , pp. 8411-8419
    • Ito, F.1    Li, Q.2    Shreiner, A.B.3    Okuyama, R.4    Jure-Kunkel, M.N.5    Teitz-Tennenbaum, S.6    Chang, A.E.7
  • 34
    • 0032080385 scopus 로고    scopus 로고
    • Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells
    • Toes, R. E., van der Voort, E. I., Schoenberger, S. P., Drijfhout, J. W., van Bloois, L., Storm, G., Kast, W. M. et al., Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells. J. Immunol. 1998. 160: 4449-4456.
    • (1998) J. Immunol , vol.160 , pp. 4449-4456
    • Toes, R.E.1    van der Voort, E.I.2    Schoenberger, S.P.3    Drijfhout, J.W.4    van Bloois, L.5    Storm, G.6    Kast, W.M.7
  • 35
    • 0029005321 scopus 로고
    • Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
    • Porgador, A. and Gilboa, E., Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes. J. Exp. Med. 1995. 182: 255-260.
    • (1995) J. Exp. Med , vol.182 , pp. 255-260
    • Porgador, A.1    Gilboa, E.2
  • 36
    • 0034193987 scopus 로고    scopus 로고
    • T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery
    • Serody, J. S., Collins, E. J., Tisch, R. M., Kuhns, J. J. and Frelinger, J. A., T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery. J. Immunol. 2000. 164: 4961-4967.
    • (2000) J. Immunol , vol.164 , pp. 4961-4967
    • Serody, J.S.1    Collins, E.J.2    Tisch, R.M.3    Kuhns, J.J.4    Frelinger, J.A.5
  • 37
    • 17844384207 scopus 로고    scopus 로고
    • Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens
    • Okada, N., Tsujino, M., Hagiwara, Y., Tada, A., Tamura, Y., Mori, K., Saito, T. et al., Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens. Br. J. Cancer 2001. 84: 1564-1570.
    • (2001) Br. J. Cancer , vol.84 , pp. 1564-1570
    • Okada, N.1    Tsujino, M.2    Hagiwara, Y.3    Tada, A.4    Tamura, Y.5    Mori, K.6    Saito, T.7
  • 38
    • 0035423368 scopus 로고    scopus 로고
    • Cutting edge: The mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2)
    • Arase, H., Saito, T., Phillips, J. H. and Lanier, L. L., Cutting edge: The mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J. Immunol. 2001. 167: 1141-1144.
    • (2001) J. Immunol , vol.167 , pp. 1141-1144
    • Arase, H.1    Saito, T.2    Phillips, J.H.3    Lanier, L.L.4
  • 40
    • 33745818581 scopus 로고    scopus 로고
    • Functional specialization of memory Th cells revealed by expression of integrin CD49b
    • Kassiotis, G., Gray, D., Kiafard, Z., Zwirner, J. and Stockinger, B., Functional specialization of memory Th cells revealed by expression of integrin CD49b. J. Immunol. 2006. 177: 968-975.
    • (2006) J. Immunol , vol.177 , pp. 968-975
    • Kassiotis, G.1    Gray, D.2    Kiafard, Z.3    Zwirner, J.4    Stockinger, B.5
  • 41
    • 0035018049 scopus 로고    scopus 로고
    • Expression of the DX5 antigen on CD81 T cells is associated with activation and subsequent cell death or memory during influenza virus infection
    • Kambayashi, T., Assarsson, E., Chambers, B. J. and Ljunggren, H. G., Expression of the DX5 antigen on CD81 T cells is associated with activation and subsequent cell death or memory during influenza virus infection. Eur. J. Immunol. 2001. 31: 1523-1530.
    • (2001) Eur. J. Immunol , vol.31 , pp. 1523-1530
    • Kambayashi, T.1    Assarsson, E.2    Chambers, B.J.3    Ljunggren, H.G.4
  • 42
    • 0033998582 scopus 로고    scopus 로고
    • Differential effects of corticosteroids during different stages of dendritic cell maturation
    • Matyszak, M. K., Citterio, S., Rescigno, M. and Ricciardi-Castagnoli, P., Differential effects of corticosteroids during different stages of dendritic cell maturation. Eur. J. Immunol. 2000. 30: 1233-1242.
    • (2000) Eur. J. Immunol , vol.30 , pp. 1233-1242
    • Matyszak, M.K.1    Citterio, S.2    Rescigno, M.3    Ricciardi-Castagnoli, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.