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Volumn 2, Issue 2, 2009, Pages 283-289

Effect of the methylenetetrahydrofolate reductase gene C677T polymorphism on C-erbB-2 methylation status and its association with cancer

Author keywords

C erbB 2; Cancer; Methylation; Methylenetetrahydrofolate reductase

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); EPIDERMAL GROWTH FACTOR RECEPTOR 2;

EID: 69249083228     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_00000097     Document Type: Article
Times cited : (11)

References (32)
  • 1
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • Baylin SB and Herman JG: DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 16: 168-174, 2000.
    • (2000) Trends Genet , vol.16 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 2
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: Too much, but also too little
    • Ehrlich M: DNA methylation in cancer: too much, but also too little. Oncogene 21: 5400-5413, 2002.
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 3
    • 0033970043 scopus 로고    scopus 로고
    • Folate and carcinogenesis: An integrated scheme
    • Choi SW and Mason JB: Folate and carcinogenesis: an integrated scheme. J Nutr 130: 129-132, 2000.
    • (2000) J Nutr , vol.130 , pp. 129-132
    • Choi, S.W.1    Mason, J.B.2
  • 5
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylene-tetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al: A candidate genetic risk factor for vascular disease: a common mutation in methylene-tetrahydrofolate reductase. Nat Genet 10: 111-113, 1995.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 6
    • 1442300286 scopus 로고    scopus 로고
    • Polymorphisms in Genes Involved in Folate Metabolism and Colorectal Neoplasia: A HuGE Review
    • DOI 10.1093/aje/kwh066
    • Sharp L and Little J: Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 159: 423-443, 2004. (Pubitemid 38280289)
    • (2004) American Journal of Epidemiology , vol.159 , Issue.5 , pp. 423-443
    • Sharp, L.1    Little, J.2
  • 7
    • 0035672957 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia
    • Franco RF, Simões BP, Tone LG, Gabellini SM, Zago MA and Falcão RP: The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia. Br J Haematol 115: 616-618, 2001.
    • (2001) Br J Haematol , vol.115 , pp. 616-618
    • Franco, R.F.1    Simões, B.P.2    Tone, L.G.3    Gabellini, S.M.4    Zago, M.A.5    Falcão, R.P.6
  • 12
    • 0035870245 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population
    • Song C, Xing D, Tan W, Wei Q and Lin D: Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population. Cancer Res 61: 3272-3275, 2001. (Pubitemid 32695011)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3272-3275
    • Song, C.1    Xing, D.2    Tan, W.3    Wei, Q.4    Lin, D.5
  • 15
    • 33846376566 scopus 로고    scopus 로고
    • No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer
    • DOI 10.1002/cbf.1274
    • Hekim N, Ergen A, Yaylim I, Yilmaz H, Zeybek U, Oztürk O and Isbir T: No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer. Cell Biochem Funct 25: 115-117, 2007. (Pubitemid 46127360)
    • (2007) Cell Biochemistry and Function , vol.25 , Issue.1 , pp. 115-117
    • Hekim, N.1    Ergen, A.2    Yaylim, I.3    Yilmaz, H.4    Zeybek, U.5    Ozturk, O.6    Isbir, T.7
  • 17
    • 10044281662 scopus 로고    scopus 로고
    • Polymorphism in folate- And methionine-metabolizing enzyme and aberrant CpG island hypermethylation in uterine cervical cancer
    • DOI 10.1016/j.ygyno.2004.09.031, PII S0090825804007917
    • Kang S, Kim JW, Kang GH, Park NH, Song YS, Kang SB and Lee HP: Polymorphism in folate- and methionine-metabolizing enzyme and aberrant CpG island hypermethylation in uterine cervical cancer. Gynecol Oncol 96: 173-180, 2005. (Pubitemid 39612433)
    • (2005) Gynecologic Oncology , vol.96 , Issue.1 , pp. 173-180
    • Kang, S.1    Kim, J.W.2    Kang, G.H.3    Park, N.H.4    Song, Y.S.5    Kang, S.B.6    Lee, H.P.7
  • 18
    • 2442539281 scopus 로고    scopus 로고
    • The Association between Methylenetetrahydrofolate Reductase Polymorphism and Promoter Methylation in Proximal Colon Cancer
    • Oyama K, Kawakami K, Maeda K, Ishiguro K and Watanabe G: The association between methylenetetrahydrofolate reductase polymorphism and promoter methylation in proximal colon cancer. Anticancer Res 24: 649-654, 2004. (Pubitemid 38625002)
    • (2004) Anticancer Research , vol.24 , Issue.2 B , pp. 649-654
    • Oyama, K.1    Kawakami, K.2    Maeda, K.3    Ishiguro, K.4    Watanabe, G.5
  • 19
    • 0022600388 scopus 로고
    • The neu oncogene encodes an epidermal growth factor receptor-related protein
    • Bargmann CI, Hung MC and Weinberg RA: The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature 319: 226-230, 1986. (Pubitemid 16128785)
    • (1986) Nature , vol.319 , Issue.6050 , pp. 226-230
    • Bargmann, C.I.1    Hung, M.C.2    Weinberg, R.A.3
  • 20
    • 34547838197 scopus 로고    scopus 로고
    • Evaluation of HER-2 gene status in gastric carcinoma using immunohistochemistry, fluorescence in situ hybridization, and real-time quantitative polymerase chain reaction
    • Kim MA, Jung EJ, Lee HS, Lee HE, Jeon YK, Yang HK and Kim WH: Evaluation of HER-2 gene status in gastric carcinoma using immunohistochemistry, fluorescence in situ hybridization, and real-time quantitative polymerase chain reaction. Hum Pathol 38: 1386-1393, 2007.
    • (2007) Hum Pathol , vol.38 , pp. 1386-1393
    • Kim, M.A.1    Jung, E.J.2    Lee, H.S.3    Lee, H.E.4    Jeon, Y.K.5    Yang, H.K.6    Kim, W.H.7
  • 21
    • 26244436607 scopus 로고    scopus 로고
    • Die her2/neu-expression beim lokal fortgeschrittenen harnblasenkarzinom: Ansatz fur eine molekulare therapie?
    • DOI 10.1055/s-2004-830253
    • Wülfing C, von Struensee D, Bierer S, Bögemann M, Hertle L and Eltze E: Expression of Her2/neu in locally advanced bladder cancer: implication for a molecular targeted therapy. Aktuelle Urol 36: 423-429, 2005. (Pubitemid 41411615)
    • (2005) Aktuelle Urologie , vol.36 , Issue.5 , pp. 423-429
    • Wulfing, C.1    Von Struensee, D.2    Bierer, S.3    Bogemann, M.4    Hertle, L.5    Eltze, E.6
  • 22
    • 15944373169 scopus 로고    scopus 로고
    • Her-2/neu over-expression correlates with more advanced disease in Iranian colorectal cancer patients
    • Tavangar SM, Shariftabrizi A and Soroush AR: Her-2/neu overexpression correlates with more advanced disease in Iranian colorectal cancer patients. Med Sci Monit 11: CR123-CR126, 2005. (Pubitemid 40445984)
    • (2005) Medical Science Monitor , vol.11 , Issue.3
    • Tavangar, S.M.1    Shariftabrizi, A.2    Soroush, A.R.3
  • 23
    • 0034638917 scopus 로고    scopus 로고
    • Overexpression of ErbB2 in cancer and ErbB2-targeting strategies
    • DOI 10.1038/sj.onc.1203972
    • Yu D and Hung MC: Overexpression of ErbB2 in cancer and ErbB2-targeting strategies. Oncogene 19: 6115-6121, 2000. (Pubitemid 32059461)
    • (2000) Oncogene , vol.19 , Issue.53 , pp. 6115-6121
    • Yu, D.1    Hung, M.-C.2
  • 24
    • 0035964487 scopus 로고    scopus 로고
    • DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes
    • DOI 10.1016/S0304-3835(01)00499-2, PII S0304383501004992
    • Hattori M, Sakamoto H, Satoh K and Yamamoto T: DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes. Cancer Lett 169: 155-164, 2001. (Pubitemid 32595563)
    • (2001) Cancer Letters , vol.169 , Issue.2 , pp. 155-164
    • Hattori, M.1    Sakamoto, H.2    Satoh, K.3    Yamamoto, T.4
  • 25
    • 0026670126 scopus 로고
    • Tumor-specific methylation patterns of erbB2 (HER2/neu) sequences in gastro-intestinal cancer
    • Holzmann K, Welter C, Klein V, Pistorius G, Seitz G and Blin N: Tumor-specific methylation patterns of erbB2 (HER2/neu) sequences in gastro-intestinal cancer. Anticancer Res 12: 1013-1018, 1992.
    • (1992) Anticancer Res , vol.12 , pp. 1013-1018
    • Holzmann, K.1    Welter, C.2    Klein, V.3    Pistorius, G.4    Seitz, G.5    Blin, N.6
  • 27
    • 23844489449 scopus 로고    scopus 로고
    • P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation
    • DOI 10.1158/1078-0432.CCR-05-0059
    • Paredes J, Albergaria A, Oliveira JT, Jerónimo C, Milanezi F and Schmitt FC: P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation. Clin Cancer Res 11: 5869-5877, 2005. (Pubitemid 41170315)
    • (2005) Clinical Cancer Research , vol.11 , Issue.16 , pp. 5869-5877
    • Paredes, J.1    Albergaria, A.2    Oliveira, J.T.3    Jeronimo, C.4    Milanezi, F.5    Schmitt, F.C.6
  • 29
    • 0022647432 scopus 로고
    • The product of the human c-erbB-2 gene: A 185-kilodalton glycoprotein with tyrosine kinase activity
    • Akiyama T, Sudo C, Ogawara H, Toyoshima K and Yamamoto T: The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity. Science 232: 1644-1646, 1986. (Pubitemid 16095607)
    • (1986) Science , vol.232 , Issue.4758 , pp. 1644-1646
    • Akiyama, T.1    Sudo, C.2    Ogawara, H.3
  • 30
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson KD: DNA methylation and human disease. Nat Rev Genet 6: 597-610, 2005.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 31
    • 0242610822 scopus 로고    scopus 로고
    • Folate, methyl-related nutrients, alcohol, and the MTHFR 677C→T polymorphism affect cancer risk: Intake recommendations
    • Bailey LB: Folate, methyl-related nutrients, alcohol, and the MTHFR 677C→T polymorphism affect cancer risk: intake recommendations. J Nutr 133: 3748S-3753S, 2003.
    • (2003) J Nutr , vol.133
    • Bailey, L.B.1
  • 32
    • 0036682379 scopus 로고    scopus 로고
    • Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors
    • Paz MF, Avila S, Fraga MF, et al: Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. Cancer 62: 4519-4524, 2002.
    • (2002) Cancer , vol.62 , pp. 4519-4524
    • Paz, M.F.1    Avila, S.2    Fraga, M.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.