The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia

British Journal of Haematology

Volumn 115, Issue 3, 2001, Pages 616-618

  Franco, Rendrik F ^a   Simões, Belinda P ^a   Tone, Luiz G ^a   Gabellini, Sérgio M ^a   Zago, Marco A ^a   Falcão, Roberto P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Acute lymphocytic leukaemia; Folate metabolism; MTHFR; Polymorphisms; Risk factor

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

ACUTE LYMPHOCYTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER DIAGNOSIS; CANCER RISK; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE MUTATION; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CONFIDENCE INTERVALS; FEMALE; GERM-LINE MUTATION; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INFANT; LEUKEMIA, B-CELL, ACUTE; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LEUKEMIA, T-CELL, ACUTE; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); ODDS RATIO; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYMORPHISM, GENETIC; PREVALENCE; RISK;

EID: 0035672957     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.03140.x     Document Type: Article

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