Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer

Genetics and Molecular Research

Volumn 5, Issue 2, 2006, Pages 315-322

  Clarizia, Alessandra D ^a   Bastos Rodrigues, Luciana ^a   Pena, Heloísa B ^a   Anacleto, Charles ^a   Rossi, Benedito ^b   Soares, Fernando A ^b   Lopes, Ademar ^b   Rocha, José Cláudio C ^b   Caballero, Otávia ^d   Camargo, Anamaria ^c   Simpson, Andrew J G ^d   Pena, Sérgio D J ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Brazil)

^d LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

Author keywords

C677T polymorphism; Colorectal cancer; Hypermethylation; Methylenetetrahydrofolate reductase; Microsatellite instability; MTHFR

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DEATH ASSOCIATED PROTEIN KINASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN MLH1; PROTEIN P14ARF; PROTEIN P16INK4A;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; METHYLATION; MICROSATELLITE INSTABILITY; PROTEIN EXPRESSION;

CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; DNA METHYLATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOMIC INSTABILITY; GENOTYPE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICROSATELLITE REPEATS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); TUMOR MARKERS, BIOLOGICAL;

EID: 33745596126     PISSN: 16765680     EISSN: 16765680     Source Type: Journal    
DOI: None     Document Type: Article

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