Signaling signatures and functional properties of anti-human CD28 superagonistic antibodies

PLoS ONE

Volumn 3, Issue 3, 2008, Pages

  Waibler, Zoe ^a   Sender, Linda Y ^a   Merten, Camilla ^b   Hartig, Roland ^b   Kliche, Stefaníe ^b   Gunzer, Matthias ^b   Reichardt, Peter ^b   Kalinke, Ulrich ^a   Schraven, Burkhart ^b  

^a PAUL EHRLICH INSTITUT   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANC 281; CALCIUM; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; MONOCLONAL ANTIBODY CD28; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; TGN 1412; TUMOR NECROSIS FACTOR ALPHA; 3 QUINUCLIDINOL 1 PHENYLCYCLOHEXANECARBOXYLATE; CD28 ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY TGN1412; QUINUCLIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CD34 SELECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE FUNCTION; MACACA; MEMORY T LYMPHOCYTE; MOLECULAR MECHANICS; NONHUMAN; PRIMATE; RHESUS MONKEY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; CELL PROLIFERATION; CYTOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; REGULATORY T LYMPHOCYTE; WESTERN BLOTTING;

PRIMATES; RODENTIA;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; BLOTTING, WESTERN; CALCIUM; CELL PROLIFERATION; FLOW CYTOMETRY; HUMANS; INTERFERON TYPE II; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MACACA FASCICULARIS; MACACA MULATTA; QUINUCLIDINES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 43049154225     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001708     Document Type: Article

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