-
1
-
-
33645300737
-
From molecule to malady
-
FM Ashcroft 2006 From molecule to malady Nature 440 440 447
-
(2006)
Nature
, vol.440
, pp. 440-447
-
-
Ashcroft, F.M.1
-
2
-
-
0029934560
-
Voltage dependence of mouse acetylcholine receptor gating: Different charge movements in di-, mono- and unliganded receptors
-
A Auerbach W Sigurdson J Chen G Akk 1996 Voltage dependence of mouse acetylcholine receptor gating: different charge movements in di-, mono- and unliganded receptors J Physiol 494 155 170
-
(1996)
J Physiol
, vol.494
, pp. 155-170
-
-
Auerbach, A.1
Sigurdson, W.2
Chen, J.3
Akk, G.4
-
4
-
-
33748573642
-
The influence of geometry, surface character, and flexibility on the permeation of ions through biological pores
-
O Beckstein M Sansom 2004 The influence of geometry, surface character, and flexibility on the permeation of ions through biological pores Phys Biol 1 42 52
-
(2004)
Phys Biol
, vol.1
, pp. 42-52
-
-
Beckstein, O.1
Sansom, M.2
-
5
-
-
33745907550
-
A hydrophobic gate in an ion channel: The closed state of the nicotinic acetylcholine receptor
-
O Beckstein MSP Sansom 2006 A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor Phys Biol 3 147 159
-
(2006)
Phys Biol
, vol.3
, pp. 147-159
-
-
Beckstein, O.1
Sansom, M.S.P.2
-
6
-
-
0242405514
-
Ion channel gating: Insights via molecular simulations
-
O Beckstein PC Biggin P Bond JN Bright C Domene A Grottesi J Holyoake MS Sansom 2003 Ion channel gating: insights via molecular simulations FEBS Lett 555 85 90
-
(2003)
FEBS Lett
, vol.555
, pp. 85-90
-
-
Beckstein, O.1
Biggin, P.C.2
Bond, P.3
Bright, J.N.4
Domene, C.5
Grottesi, A.6
Holyoake, J.7
Sansom, M.S.8
-
8
-
-
0026658377
-
Voltage dependence of acetylcholine receptor channel gating in rat myoballs
-
LD Chabala 1992 Voltage dependence of acetylcholine receptor channel gating in rat myoballs J Gen Physiol 100 729 748
-
(1992)
J Gen Physiol
, vol.100
, pp. 729-748
-
-
Chabala, L.D.1
-
9
-
-
28844448877
-
Channel opening motion of α7 nicotinic acetylcholine receptor as suggested by normal mode analysis
-
X Cheng B Lu B Grant RJ Law JA McCammon 2006 Channel opening motion of α7 nicotinic acetylcholine receptor as suggested by normal mode analysis J Mol Biol 355 310 324
-
(2006)
J Mol Biol
, vol.355
, pp. 310-324
-
-
Cheng, X.1
Lu, B.2
Grant, B.3
Law, R.J.4
McCammon, J.A.5
-
10
-
-
0032708637
-
Permeation of ions across the potassium channel: Brownian dynamics studies
-
S Chung T Allen M Hoyles S Kuyucak 1999 Permeation of ions across the potassium channel: Brownian dynamics studies Biophys J 77 2517 2533
-
(1999)
Biophys J
, vol.77
, pp. 2517-2533
-
-
Chung, S.1
Allen, T.2
Hoyles, M.3
Kuyucak, S.4
-
11
-
-
0036151669
-
Conducting-state properties of the KcsA potassium channel from molecular and Brownian dynamics simulations
-
SH Chung TW Allen S Kuyucak 2002 Conducting-state properties of the KcsA potassium channel from molecular and Brownian dynamics simulations Biophys J 82 628 645
-
(2002)
Biophys J
, vol.82
, pp. 628-645
-
-
Chung, S.H.1
Allen, T.W.2
Kuyucak, S.3
-
12
-
-
2442548865
-
Theoretical conformation of the closed and open states of the acetylcholine receptor channel
-
B Corry 2004 Theoretical conformation of the closed and open states of the acetylcholine receptor channel Biochim Biophys Acta 1663 2 5
-
(2004)
Biochim Biophys Acta
, vol.1663
, pp. 2-5
-
-
Corry, B.1
-
13
-
-
33646187879
-
An energy-efficient gating mechanism in the acetylcholine receptor channel suggested by molecular and Brownian dynamics
-
B Corry 2006 An energy-efficient gating mechanism in the acetylcholine receptor channel suggested by molecular and Brownian dynamics Biophys J 90 799 810
-
(2006)
Biophys J
, vol.90
, pp. 799-810
-
-
Corry, B.1
-
14
-
-
0035132981
-
Mechanisms of permeation and selectivity in calcium channels
-
B Corry TW Allen S Kuyucak SH Chung 2001 Mechanisms of permeation and selectivity in calcium channels Biophys J 80 195 214
-
(2001)
Biophys J
, vol.80
, pp. 195-214
-
-
Corry, B.1
Allen, T.W.2
Kuyucak, S.3
Chung, S.H.4
-
15
-
-
1142310688
-
Conduction mechanisms of chloride ions in ClC-type channels
-
B Corry M O'Mara SH Chung 2004 Conduction mechanisms of chloride ions in ClC-type channels Biophys J 86 846 860
-
(2004)
Biophys J
, vol.86
, pp. 846-860
-
-
Corry, B.1
O'Mara, M.2
Chung, S.H.3
-
16
-
-
41649119572
-
Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
-
GD Cymes C Grosman 2008 Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer Nat Struct Mol Biol 15 389 396
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 389-396
-
-
Cymes, G.D.1
Grosman, C.2
-
17
-
-
33846823909
-
Particle mesh Ewald: An Nlog(N) method for Ewald sums in large systems
-
T Darden D York L Pedersen 1993 Particle mesh Ewald: an Nlog(N) method for Ewald sums in large systems J Chem Phys 98 10089 10092
-
(1993)
J Chem Phys
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
19
-
-
0034100847
-
Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels
-
C Grosman A Auerbach 2000 Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels J Gen Physiol 115 621 635
-
(2000)
J Gen Physiol
, vol.115
, pp. 621-635
-
-
Grosman, C.1
Auerbach, A.2
-
20
-
-
41149168686
-
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
-
RJC Hilf R Dutzler 2008 X-ray structure of a prokaryotic pentameric ligand-gated ion channel Nature 452 375 380
-
(2008)
Nature
, vol.452
, pp. 375-380
-
-
Hilf, R.J.C.1
Dutzler, R.2
-
21
-
-
58149242730
-
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
-
RJC Hilf R Dutzler 2009 Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel Nature 457 115 119
-
(2009)
Nature
, vol.457
, pp. 115-119
-
-
Hilf, R.J.C.1
Dutzler, R.2
-
22
-
-
0032297748
-
Solutions of Poisson's equation in channel-like geometries
-
M Hoyles S Kuyucak SH Chung 1998 Solutions of Poisson's equation in channel-like geometries Comput Phys Commun 115 45 68
-
(1998)
Comput Phys Commun
, vol.115
, pp. 45-68
-
-
Hoyles, M.1
Kuyucak, S.2
Chung, S.H.3
-
23
-
-
0035829539
-
Water conduction through the hydrophobic channel of a carbon nanotube
-
G Hummer JC Rasaiah JP Noworyta 2001 Water conduction through the hydrophobic channel of a carbon nanotube Nature 414 188 190
-
(2001)
Nature
, vol.414
, pp. 188-190
-
-
Hummer, G.1
Rasaiah, J.C.2
Noworyta, J.P.3
-
24
-
-
0022628717
-
Kinetics of unliganded acetylcholine receptor channel gating
-
MB Jackson 1986 Kinetics of unliganded acetylcholine receptor channel gating Biophys J 49 663 672
-
(1986)
Biophys J
, vol.49
, pp. 663-672
-
-
Jackson, M.B.1
-
25
-
-
15244355046
-
Fifty years of progress in ion channel research
-
PC Jordan 2005 Fifty years of progress in ion channel research IEEE T NanoBiosci 4 3 9
-
(2005)
IEEE T NanoBiosci
, vol.4
, pp. 3-9
-
-
Jordan, P.C.1
-
26
-
-
18744363916
-
A gating mechanism proposed from a simulation of a human α7 nicotinic acetylcholine receptor
-
RJ Law RH Henchman JA McCammon 2005 A gating mechanism proposed from a simulation of a human α7 nicotinic acetylcholine receptor Proc Natl Acad Sci USA 102 6813 6818
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6813-6818
-
-
Law, R.J.1
Henchman, R.H.2
McCammon, J.A.3
-
27
-
-
0021307478
-
Single-channel acetylcholine receptor kinetics
-
MD Leibowitz VE Dionne 1984 Single-channel acetylcholine receptor kinetics Biophys J 45 153 163
-
(1984)
Biophys J
, vol.45
, pp. 153-163
-
-
Leibowitz, M.D.1
Dionne, V.E.2
-
28
-
-
0002786541
-
Brownian dynamics study of ion transport in the vestibule of membrane channels
-
SC Li M Hoyles S Kuyucak SH Chung 1998 Brownian dynamics study of ion transport in the vestibule of membrane channels Biophys J 74 37 47
-
(1998)
Biophys J
, vol.74
, pp. 37-47
-
-
Li, S.C.1
Hoyles, M.2
Kuyucak, S.3
Chung, S.H.4
-
30
-
-
0025850235
-
Opening rate of acetylcholine receptor channels
-
Y Liu JP Dilger 1991 Opening rate of acetylcholine receptor channels Biophys J 60 424 432
-
(1991)
Biophys J
, vol.60
, pp. 424-432
-
-
Liu, Y.1
Dilger, J.P.2
-
31
-
-
0041784950
-
All-atom empirical potential for molecular modelling and dynamics studies of proteins.
-
MacKerell Jr AD, Bashford D, Bellott M, Dunbrack Jr RL, Evanseck JD, Field MJ, Fischer S, Gao J, Guo H, Ha S, Joseph-McCarthy D, Kuchnir L, Kuczera K, Lau FTK, Mattos C, Michnick S, Ngo T, Nguyen DT, Prodhom B, Reiher III WE, Roux B, Schlenkrich M, Smith JC, Stote R, Straub J, Watanabe M, Wiórkiewicz-Kuczera J, Yin D, Karplus M (1998) All-atom empirical potential for molecular modelling and dynamics studies of proteins. J Phys Chem B 102:3586-3616
-
(1998)
J Phys Chem B
, vol.102
, pp. 3586-3616
-
-
MacKerell Jr., A.D.1
Bashford, D.2
Bellott, M.3
Dunbrack Jr., R.L.4
Evanseck, J.D.5
Field, M.J.6
Fischer, S.7
Gao, J.8
Guo, H.9
Ha, S.10
Joseph-McCarthy, D.11
Kuchnir, L.12
Kuczera, K.13
Lau, F.T.K.14
Mattos, C.15
Michnick, S.16
Ngo, T.17
Nguyen, D.T.18
Prodhom, B.19
Reiher III, W.E.20
Roux, B.21
Schlenkrich, M.22
Smith, J.C.23
Stote, R.24
Straub, J.25
Watanabe, M.26
Wiórkiewicz-Kuczera, J.27
Yin, D.28
Karplus, M.29
more..
-
32
-
-
0015339664
-
The effect of voltage on the time course of end-plate currents
-
KL Magleby CF Stevens 1972 The effect of voltage on the time course of end-plate currents J Physiol 223 151 171
-
(1972)
J Physiol
, vol.223
, pp. 151-171
-
-
Magleby, K.L.1
Stevens, C.F.2
-
33
-
-
0038112088
-
Structure and gating mechanism of the acetylcholine receptor pore
-
A Miyazawa Y Fujiyoshi N Unwin 2003 Structure and gating mechanism of the acetylcholine receptor pore Nature 423 949 955
-
(2003)
Nature
, vol.423
, pp. 949-955
-
-
Miyazawa, A.1
Fujiyoshi, Y.2
Unwin, N.3
-
34
-
-
38149078849
-
Estimating the dielectric constant of the channel protein and pore
-
JA Ng T Vora V Krishnamurthy SH Chung 2008 Estimating the dielectric constant of the channel protein and pore Eur Biophys J 37 213 222
-
(2008)
Eur Biophys J
, vol.37
, pp. 213-222
-
-
Ng, J.A.1
Vora, T.2
Krishnamurthy, V.3
Chung, S.H.4
-
36
-
-
0031781630
-
State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor: Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the α subunit
-
J Pascual A Karlin 1998 State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor: inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the α subunit J Gen Physiol 111 717 739
-
(1998)
J Gen Physiol
, vol.111
, pp. 717-739
-
-
Pascual, J.1
Karlin, A.2
-
37
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
JC Phillips R Braun W Wang J Gumbart E Tajkhorshid E Villa C Chipot RD Skeel L Kale K Schulten 2005 Scalable molecular dynamics with NAMD J Comput Chem 26 1781 1802
-
(2005)
J Comput Chem
, vol.26
, pp. 1781-1802
-
-
Phillips, J.C.1
Braun, R.2
Wang, W.3
Gumbart, J.4
Tajkhorshid, E.5
Villa, E.6
Chipot, C.7
Skeel, R.D.8
Kale, L.9
Schulten, K.10
-
38
-
-
0017646559
-
Rates and equilibria at the acetylcholine receptor of electrophorus electroplaques
-
RE Sheridan HA Lester 1977 Rates and equilibria at the acetylcholine receptor of electrophorus electroplaques J Gen Physiol 70 187 219
-
(1977)
J Gen Physiol
, vol.70
, pp. 187-219
-
-
Sheridan, R.E.1
Lester, H.A.2
-
39
-
-
33645302360
-
Recent advances in Cys-loop receptor structure and function
-
SM Sine AG Engel 2006 Recent advances in Cys-loop receptor structure and function Nature 440 448 455
-
(2006)
Nature
, vol.440
, pp. 448-455
-
-
Sine, S.M.1
Engel, A.G.2
-
40
-
-
33846828514
-
Ion conduction through MscS as determined by electrophysiology and simulation
-
M Sotomayor V Vasquez E Perozo K Schulten 2007 Ion conduction through MscS as determined by electrophysiology and simulation Biophys J 92 886 902
-
(2007)
Biophys J
, vol.92
, pp. 886-902
-
-
Sotomayor, M.1
Vasquez, V.2
Perozo, E.3
Schulten, K.4
-
41
-
-
33646200263
-
Voltage-dependent hydration and conduction properties of the hydrophobic pore of the mechanosensitive channel of small conductance
-
SA Spronk DE Elmore DA Dougherty 2006 Voltage-dependent hydration and conduction properties of the hydrophobic pore of the mechanosensitive channel of small conductance Biophys J 90 3555 3569
-
(2006)
Biophys J
, vol.90
, pp. 3555-3569
-
-
Spronk, S.A.1
Elmore, D.E.2
Dougherty, D.A.3
-
43
-
-
0028921479
-
Acetylcholine receptor channel imaged in the open state
-
N Unwin 1995 Acetylcholine receptor channel imaged in the open state Nature 373 37 43
-
(1995)
Nature
, vol.373
, pp. 37-43
-
-
Unwin, N.1
-
44
-
-
0242488935
-
Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy
-
N Unwin 2003 Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy FEBS Lett 555 91 95
-
(2003)
FEBS Lett
, vol.555
, pp. 91-95
-
-
Unwin, N.1
-
45
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
-
N Unwin 2005 Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution J Mol Biol 346 967 989
-
(2005)
J Mol Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
47
-
-
0032102496
-
The location of the gate in the acetylcholine receptor channel
-
GG Wilson A Karlin 1998 The location of the gate in the acetylcholine receptor channel Neuron 20 1269 1281
-
(1998)
Neuron
, vol.20
, pp. 1269-1281
-
-
Wilson, G.G.1
Karlin, A.2
|