The RD1 locus in the Mycobacterium tuberculosis genome contributes to activation of caspase-1 via induction of potassium ion efflux in infected macrophages

Infection and Immunity

Volumn 77, Issue 9, 2009, Pages 3992-4001

  Kurenuma, Takeshi ^a   Kawamura, Ikuo ^a   Hara, Hideki ^a   Uchiyama, Ryosuke ^b   Daim, Sylvia ^a   Dewamitta, Sita Ramyamali ^a   Sakai, Shunsuke ^a   Tsuchiya, Kohsuke ^a   Nomura, Takamasa ^a   Mitsuyama, Masao ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; NIGERICIN; POTASSIUM CHLORIDE; POTASSIUM ION; PURINERGIC P2X7 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFUSION; ENZYME ACTIVATION; ENZYME SYNTHESIS; FEMALE; GENE LOCUS; IMMUNE RESPONSE; IMMUNITY; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUBERCULOSIS;

ANIMALS; CARRIER PROTEINS; CASPASE 1; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; FEMALE; GENOME, BACTERIAL; INTERFERON-BETA; INTERLEUKIN-18; INTERLEUKIN-1BETA; INTERLEUKIN-6; ION TRANSPORT; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; NIGERICIN; POTASSIUM; RECEPTORS, PURINERGIC P2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69049089842     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00015-09     Document Type: Article

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