-
1
-
-
0026548697
-
Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation
-
J Lerma R Martin del Rio 1992 Chloride transport blockers prevent N-methyl-D-aspartate receptor-channel complex activation Mol Pharmacol 41 217 222
-
(1992)
Mol Pharmacol
, vol.41
, pp. 217-222
-
-
Lerma, J.1
Martin Del Rio, R.2
-
2
-
-
0032866803
-
A receptors by the non-steroidal anti-inflammatory agent, mefenamic acid
-
10.1046/j.1460-9568.1999.00709.x
-
A receptors by the non-steroidal anti-inflammatory agent, mefenamic acid Eur J Neurosci 11 2897 2905 10.1046/j.1460-9568.1999.00709.x
-
(1999)
Eur J Neurosci
, vol.11
, pp. 2897-2905
-
-
Halliwell, R.F.1
Thomas, P.2
Patten, D.3
James, C.H.4
Martinez-Torres, A.5
Miledi, R.6
Smart, T.G.7
-
3
-
-
0041353559
-
A receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug
-
10.1124/mol.64.3.753
-
A receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug Mol Pharmacol 64 753 763 10.1124/mol.64.3.753
-
(2003)
Mol Pharmacol
, vol.64
, pp. 753-763
-
-
Sinkkonen, S.T.1
Mansikkamaki, S.2
Moykkynen, T.3
Luddens, H.4
Uusi-Oukari, M.5
Korpi, E.R.6
-
5
-
-
0025372566
-
Flufenamic acid, mefenamic acid and niflumic acid inhibit single nonselective cation channels in the rat exocrine pancreas
-
10.1016/0014-5793(90)80977-Q
-
H Gogelein D Dahlem HC Englert HJ Lang 1990 Flufenamic acid, mefenamic acid and niflumic acid inhibit single nonselective cation channels in the rat exocrine pancreas FEBS Lett 268 79 82 10.1016/0014-5793(90)80977-Q
-
(1990)
FEBS Lett
, vol.268
, pp. 79-82
-
-
Gogelein, H.1
Dahlem, D.2
Englert, H.C.3
Lang, H.J.4
-
6
-
-
0028308919
-
Action of niflumic acid on evoked and spontaneous calcium-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein
-
RC Hogg Q Wang WA Large 1994 Action of niflumic acid on evoked and spontaneous calcium-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein Br J Pharmacol 112 977 984
-
(1994)
Br J Pharmacol
, vol.112
, pp. 977-984
-
-
Hogg, R.C.1
Wang, Q.2
Large, W.A.3
-
7
-
-
0032810212
-
+ channel, by meclofenamic acid
-
10.1016/S0014-2999(99)00485-9
-
+ channel, by meclofenamic acid Eur J Pharmacol 378 349 356 10.1016/S0014-2999(99)00485-9
-
(1999)
Eur J Pharmacol
, vol.378
, pp. 349-356
-
-
Lee, Y.T.1
Wang, Q.2
-
8
-
-
30044450910
-
Activation and inhibition of kidney CLC-K chloride channels by fenamates
-
A Liantonio A Picollo E Babini G Carbonara G Fracchiolla F Loiodice V Tortorella M Pusch DC Camerino 2006 Activation and inhibition of kidney CLC-K chloride channels by fenamates Mol Pharmacol 69 165 173
-
(2006)
Mol Pharmacol
, vol.69
, pp. 165-173
-
-
Liantonio, A.1
Picollo, A.2
Babini, E.3
Carbonara, G.4
Fracchiolla, G.5
Loiodice, F.6
Tortorella, V.7
Pusch, M.8
Camerino, D.C.9
-
9
-
-
0037064306
-
Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes
-
10.1016/S0014-2999(02)02330-0
-
AP Malykhina F Shoeb HI Akbarali 2002 Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes Eur J Pharmacol 452 269 277 10.1016/S0014-2999(02)02330-0
-
(2002)
Eur J Pharmacol
, vol.452
, pp. 269-277
-
-
Malykhina, A.P.1
Shoeb, F.2
Akbarali, H.I.3
-
10
-
-
0034889330
-
Fenamates: A novel class of reversible gap junction blockers
-
EG Harks AD de Roos PH Peters LH de Haan A Brouwer DL Ypey EJ van Zoelen AP Theuvenet 2001 Fenamates: a novel class of reversible gap junction blockers J Pharmacol Exp Ther 298 1033 1041
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 1033-1041
-
-
Harks, E.G.1
De Roos, A.D.2
Peters, P.H.3
De Haan, L.H.4
Brouwer, A.5
Ypey, D.L.6
Van Zoelen, E.J.7
Theuvenet, A.P.8
-
11
-
-
0035395177
-
Niflumic acid modulates uncoupled substrate-gated conductances in the human glutamate transporter EAAT4
-
10.1111/j.1469-7793.2001.00159.x
-
MV Poulsen RJ Vandenberg 2001 Niflumic acid modulates uncoupled substrate-gated conductances in the human glutamate transporter EAAT4 J Physiol 534 159 167 10.1111/j.1469-7793.2001.00159.x
-
(2001)
J Physiol
, vol.534
, pp. 159-167
-
-
Poulsen, M.V.1
Vandenberg, R.J.2
-
12
-
-
33644664236
-
Arachidonic acid elicits a substrate-gated proton current associated with the glutamate transporter EAAT4
-
10.1038/355
-
WA Fairman MS Sonders GH Murdoch SG Amara 1998 Arachidonic acid elicits a substrate-gated proton current associated with the glutamate transporter EAAT4 Nat Neurosci 1 105 113 10.1038/355
-
(1998)
Nat Neurosci
, vol.1
, pp. 105-113
-
-
Fairman, W.A.1
Sonders, M.S.2
Murdoch, G.H.3
Amara, S.G.4
-
13
-
-
0028911077
-
Differential modulation of human glutamate transporter subtypes by arachidonic acid
-
10.1074/jbc.270.12.6433
-
N Zerangue JL Arriza SG Amara MP Kavanaugh 1995 Differential modulation of human glutamate transporter subtypes by arachidonic acid J Biol Chem 270 6433 6435 10.1074/jbc.270.12.6433
-
(1995)
J Biol Chem
, vol.270
, pp. 6433-6435
-
-
Zerangue, N.1
Arriza, J.L.2
Amara, S.G.3
Kavanaugh, M.P.4
-
14
-
-
0024554279
-
Clinical pharmacokinetics of nonsteroidal anti-inflammatory drugs in the cerebrospinal fluid
-
10.1016/0753-3322(89)90140-6
-
B Bannwarth P Netter J Pourel RJ Royer A Gaucher 1989 Clinical pharmacokinetics of nonsteroidal anti-inflammatory drugs in the cerebrospinal fluid Biomed Pharmacother 43 121 126 10.1016/0753-3322(89)90140-6
-
(1989)
Biomed Pharmacother
, vol.43
, pp. 121-126
-
-
Bannwarth, B.1
Netter, P.2
Pourel, J.3
Royer, R.J.4
Gaucher, A.5
-
15
-
-
0029917887
-
Anti-inflammatory drugs in the fight against Alzheimer's disease
-
10.1111/j.1749-6632.1996.tb34421.x
-
PL McGeer EG McGeer 1996 Anti-inflammatory drugs in the fight against Alzheimer's disease Ann N Y Acad Sci 777 213 220 10.1111/j.1749-6632.1996. tb34421.x
-
(1996)
Ann N Y Acad Sci
, vol.777
, pp. 213-220
-
-
McGeer, P.L.1
McGeer, E.G.2
-
16
-
-
7244226629
-
Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: Old and new mechanisms of action
-
10.1111/j.1471-4159.2004.02743.x
-
L Gasparini E Ongini G Wenk 2004 Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action J Neurochem 91 521 536 10.1111/j.1471-4159.2004.02743.x
-
(2004)
J Neurochem
, vol.91
, pp. 521-536
-
-
Gasparini, L.1
Ongini, E.2
Wenk, G.3
-
18
-
-
30044447532
-
Mefenamic acid shows neuroprotective effects and improves cognitive impairment in in vitro and in vivo Alzheimer's disease models
-
Y Joo HS Kim RS Woo CH Park KY Shin JP Lee KA Chang S Kim YH Suh 2006 Mefenamic acid shows neuroprotective effects and improves cognitive impairment in in vitro and in vivo Alzheimer's disease models Mol Pharmacol 69 76 84
-
(2006)
Mol Pharmacol
, vol.69
, pp. 76-84
-
-
Joo, Y.1
Kim, H.S.2
Woo, R.S.3
Park, C.H.4
Shin, K.Y.5
Lee, J.P.6
Chang, K.A.7
Kim, S.8
Suh, Y.H.9
-
19
-
-
0032548765
-
Fenamates protect neurons against ischemic and excitotoxic injury in chick embryo retina
-
10.1016/S0304-3940(98)00081-0
-
Q Chen JW Olney PD Lukasiewicz T Almli C Romano 1998 Fenamates protect neurons against ischemic and excitotoxic injury in chick embryo retina Neurosci Lett 242 163 166 10.1016/S0304-3940(98)00081-0
-
(1998)
Neurosci Lett
, vol.242
, pp. 163-166
-
-
Chen, Q.1
Olney, J.W.2
Lukasiewicz, P.D.3
Almli, T.4
Romano, C.5
-
20
-
-
0025070929
-
Toxic effects of nonsteroidal anti-inflammatory drugs in overdose. An overview of recent evidence on clinical effects and dose-response relationships
-
10.2165/00002018-199005040-00003
-
SC Smolinske AH Hall SA Vandenberg DG Spoerke PV McBride 1990 Toxic effects of nonsteroidal anti-inflammatory drugs in overdose. An overview of recent evidence on clinical effects and dose-response relationships Drug Saf 5 252 274 10.2165/00002018-199005040-00003
-
(1990)
Drug Saf
, vol.5
, pp. 252-274
-
-
Smolinske, S.C.1
Hall, A.H.2
Vandenberg, S.A.3
Spoerke, D.G.4
McBride, P.V.5
-
21
-
-
0028168114
-
Excitotoxic mechanisms in the pathogenesis of dementia
-
10.1016/0197-0186(94)90064-7
-
PR Dodd HL Scott RI Westphalen 1994 Excitotoxic mechanisms in the pathogenesis of dementia Neurochem Int 25 203 219 10.1016/0197-0186(94)90064-7
-
(1994)
Neurochem Int
, vol.25
, pp. 203-219
-
-
Dodd, P.R.1
Scott, H.L.2
Westphalen, R.I.3
-
22
-
-
0030872412
-
Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression
-
10.1097/00005072-199708000-00008
-
S Li M Mallory M Alford S Tanaka E Masliah 1997 Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression J Neuropathol Exp Neurol 56 901 911 10.1097/00005072-199708000-00008
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 901-911
-
-
Li, S.1
Mallory, M.2
Alford, M.3
Tanaka, S.4
Masliah, E.5
-
23
-
-
0036479889
-
Aberrant expression of the glutamate transporter excitatory amino acid transporter 1 (EAAT1) in Alzheimer's disease
-
HL Scott DV Pow AE Tannenberg PR Dodd 2002 Aberrant expression of the glutamate transporter excitatory amino acid transporter 1 (EAAT1) in Alzheimer's disease J Neurosci 22 RC206
-
(2002)
J Neurosci
, vol.22
, pp. 206
-
-
Scott, H.L.1
Pow, D.V.2
Tannenberg, A.E.3
Dodd, P.R.4
-
24
-
-
0037312280
-
Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a
-
10.1046/j.1471-4159.2003.01549.x
-
RJ Pearlman KR Aubrey RJ Vandenberg 2003 Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a J Neurochem 84 592 601 10.1046/j.1471-4159.2003.01549.x
-
(2003)
J Neurochem
, vol.84
, pp. 592-601
-
-
Pearlman, R.J.1
Aubrey, K.R.2
Vandenberg, R.J.3
-
26
-
-
0032511029
-
Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2
-
10.1074/jbc.273.24.14698
-
AD Mitrovic SG Amara GA Johnston RJ Vandenberg 1998 Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2 J Biol Chem 273 14698 14706 10.1074/jbc.273.24.14698
-
(1998)
J Biol Chem
, vol.273
, pp. 14698-14706
-
-
Mitrovic, A.D.1
Amara, S.G.2
Johnston, G.A.3
Vandenberg, R.J.4
-
27
-
-
0033921196
-
Molecular basis for proton regulation of glycine transport by glycine transporter subtype 1b
-
KR Aubrey AD Mitrovic RJ Vandenberg 2000 Molecular basis for proton regulation of glycine transport by glycine transporter subtype 1b Mol Pharmacol 58 129 135
-
(2000)
Mol Pharmacol
, vol.58
, pp. 129-135
-
-
Aubrey, K.R.1
Mitrovic, A.D.2
Vandenberg, R.J.3
-
28
-
-
0033043034
-
Characterization of multiple forms of the human glycine transporter type-2
-
10.1016/S0169-328X(99)00135-7
-
MJ Gallagher LH Burgess KR Brunden 1999 Characterization of multiple forms of the human glycine transporter type-2 Brain Res Mol Brain Res 70 101 115 10.1016/S0169-328X(99)00135-7
-
(1999)
Brain Res Mol Brain Res
, vol.70
, pp. 101-115
-
-
Gallagher, M.J.1
Burgess, L.H.2
Brunden, K.R.3
-
29
-
-
2542493963
-
2+ inhibits glycine transport by glycine transporter subtype 1b
-
10.1074/jbc.M312484200
-
2+ inhibits glycine transport by glycine transporter subtype 1b J Biol Chem 279 22983 22991 10.1074/jbc.M312484200
-
(2004)
J Biol Chem
, vol.279
, pp. 22983-22991
-
-
Ju, P.1
Aubrey, K.R.2
Vandenberg, R.J.3
-
30
-
-
0030946093
-
Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2
-
RJ Vandenberg AD Mitrovic M Chebib VJ Balcar GA Johnston 1997 Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2 Mol Pharmacol 51 809 815
-
(1997)
Mol Pharmacol
, vol.51
, pp. 809-815
-
-
Vandenberg, R.J.1
Mitrovic, A.D.2
Chebib, M.3
Balcar, V.J.4
Johnston, G.A.5
-
31
-
-
0031849828
-
Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions
-
RJ Vandenberg AD Mitrovic GA Johnston 1998 Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions Mol Pharmacol 54 189 196
-
(1998)
Mol Pharmacol
, vol.54
, pp. 189-196
-
-
Vandenberg, R.J.1
Mitrovic, A.D.2
Johnston, G.A.3
-
32
-
-
0034721194
-
Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors
-
10.1021/jm000004e
-
AS Kalgutkar AB Marnett BC Crews RP Remmel LJ Marnett 2000 Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors J Med Chem 43 2860 2870 10.1021/jm000004e
-
(2000)
J Med Chem
, vol.43
, pp. 2860-2870
-
-
Kalgutkar, A.S.1
Marnett, A.B.2
Crews, B.C.3
Remmel, R.P.4
Marnett, L.J.5
-
33
-
-
8544250631
-
Allosteric modulation of neurotransmitter transporters at excitatory synapses
-
10.1016/j.ejps.2004.05.006
-
RJ Vandenberg P Ju KR Aubrey RM Ryan AD Mitrovic 2004 Allosteric modulation of neurotransmitter transporters at excitatory synapses Eur J Pharm Sci 23 1 11 10.1016/j.ejps.2004.05.006
-
(2004)
Eur J Pharm Sci
, vol.23
, pp. 1-11
-
-
Vandenberg, R.J.1
Ju, P.2
Aubrey, K.R.3
Ryan, R.M.4
Mitrovic, A.D.5
-
34
-
-
0035854771
-
2+ inhibits the anion conductance of the glutamate transporter EAAT4
-
10.1074/jbc.M011318200
-
2+ inhibits the anion conductance of the glutamate transporter EAAT4 J Biol Chem 276 26071 26076 10.1074/jbc.M011318200
-
(2001)
J Biol Chem
, vol.276
, pp. 26071-26076
-
-
Mitrovic, A.D.1
Plesko, F.2
Vandenberg, R.J.3
-
35
-
-
0035909950
-
Sulfhydryl modification of V449C in the glutamate transporter EAAT1 abolishes substrate transport but not the substrate-gated anion conductance
-
10.1073/pnas.011400198
-
RP Seal Y Shigeri S Eliasof BH Leighton SG Amara 2001 Sulfhydryl modification of V449C in the glutamate transporter EAAT1 abolishes substrate transport but not the substrate-gated anion conductance Proc Natl Acad Sci USA 98 15324 15329 10.1073/pnas.011400198
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15324-15329
-
-
Seal, R.P.1
Shigeri, Y.2
Eliasof, S.3
Leighton, B.H.4
Amara, S.G.5
-
36
-
-
0030068054
-
Involvement of arginine 120, glutamate 524, tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1
-
10.1074/jbc.271.33.20175
-
DK Bhattacharyya M Lecomte CJ Rieke M Garavito WL Smith 1996 Involvement of arginine 120, glutamate 524, tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1 J Biol Chem 271 2179 2184 10.1074/jbc.271.33.20175
-
(1996)
J Biol Chem
, vol.271
, pp. 2179-2184
-
-
Bhattacharyya, D.K.1
Lecomte, M.2
Rieke, C.J.3
Garavito, M.4
Smith, W.L.5
-
37
-
-
0030783709
-
The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs
-
GM Greig DA Francis JP Falgueyret M Ouellet MD Percival P Roy C Bayly JA Mancini GP O'Neill 1997 The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs Mol Pharmacol 52 829 838
-
(1997)
Mol Pharmacol
, vol.52
, pp. 829-838
-
-
Greig, G.M.1
Francis, D.A.2
Falgueyret, J.P.3
Ouellet, M.4
Percival, M.D.5
Roy, P.6
Bayly, C.7
Mancini, J.A.8
O'Neill, G.P.9
-
38
-
-
0028783912
-
Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety
-
10.1074/jbc.270.49.29372
-
JA Mancini D Riendeau JP Falgueyret PJ Vickers GP O'Neill 1995 Arginine 120 of prostaglandin G/H synthase-1 is required for the inhibition by nonsteroidal anti-inflammatory drugs containing a carboxylic acid moiety J Biol Chem 270 29372 29377 10.1074/jbc.270.49.29372
-
(1995)
J Biol Chem
, vol.270
, pp. 29372-29377
-
-
Mancini, J.A.1
Riendeau, D.2
Falgueyret, J.P.3
Vickers, P.J.4
O'Neill, G.P.5
-
39
-
-
0028139275
-
Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase
-
10.1073/pnas.91.23.11202
-
RA Copeland JM Williams J Giannaras S Nurnberg M Covington D Pinto S Pick JM Trzaskos 1994 Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase Proc Natl Acad Sci USA 91 11202 11206 10.1073/pnas.91.23.11202
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11202-11206
-
-
Copeland, R.A.1
Williams, J.M.2
Giannaras, J.3
Nurnberg, S.4
Covington, M.5
Pinto, D.6
Pick, S.7
Trzaskos, J.M.8
-
40
-
-
0029040041
-
Biochemistry of prostaglandin endoperoxide H synthase-1 and synthase-2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs
-
WL Smith DL DeWitt 1995 Biochemistry of prostaglandin endoperoxide H synthase-1 and synthase-2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs Semin Nephrol 15 179 194
-
(1995)
Semin Nephrol
, vol.15
, pp. 179-194
-
-
Smith, W.L.1
Dewitt, D.L.2
-
41
-
-
0344938274
-
The structural and electronical factors that contribute affinity for the time-dependent inhibition of PGHS-1 by indomethacin, diclofenac and fenamates
-
10.1023/A:1008094616324
-
R Pouplana C Perez J Sanchez JJ Lozano P Puig-Parellada 1999 The structural and electronical factors that contribute affinity for the time-dependent inhibition of PGHS-1 by indomethacin, diclofenac and fenamates J Comput Aided Mol Des 13 297 313 10.1023/A:1008094616324
-
(1999)
J Comput Aided Mol des
, vol.13
, pp. 297-313
-
-
Pouplana, R.1
Perez, C.2
Sanchez, J.3
Lozano, J.J.4
Puig-Parellada, P.5
-
42
-
-
0000151210
-
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs
-
10.1073/pnas.72.12.4863
-
LH Rome WE Lands 1975 Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs Proc Natl Acad Sci USA 72 4863 4865 10.1073/pnas.72.12.4863
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 4863-4865
-
-
Rome, L.H.1
Lands, W.E.2
-
43
-
-
28044448943
-
Pericapillary haem-rich deposits: Evidence for microhaemorrhages in aging human cerebral cortex
-
10.1038/sj.jcbfm.9600155
-
KM Cullen Z Kocsi J Stone 2005 Pericapillary haem-rich deposits: evidence for microhaemorrhages in aging human cerebral cortex J Cereb Blood Flow Metab 25 1656 1667 10.1038/sj.jcbfm.9600155
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, pp. 1656-1667
-
-
Cullen, K.M.1
Kocsi, Z.2
Stone, J.3
|