The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs

Molecular Pharmacology

Volumn 52, Issue 5, 1997, Pages 829-838

  Greig, Gillian M ^a   Francis, Donna A ^a   Falgueyret, Jean Pierre ^a   Ouellet, Marc ^a   Percival, M David ^a   Roy, Patrick ^a   Bayly, Christopher ^a   Mancini, Joseph A ^a   O'Neill, Gary P ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; ARACHIDONIC ACID; DICLOFENAC; FLOSULIDE; FLURBIPROFEN; INDOMETACIN; L 588983; L 745296; L 746483; L 761066; MECLOFENAMIC ACID; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CRYSTAL STRUCTURE; DOSE TIME EFFECT RELATION; DRUG BINDING; DRUG POTENCY; ENZYME ACTIVE SITE; ENZYME INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN INTERACTION; SHEEP;

EID: 0030783709     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.52.5.829     Document Type: Article

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