Receptor subtype-dependent positive and negative modulation of GABA A receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug

Molecular Pharmacology

Volumn 64, Issue 3, 2003, Pages 753-763

  Sinkkonen, Saku T ^a,c   Mansikkamäki, Salla ^a   Möykkynen, Tommi ^c   Lüddens, Hartmut ^b   Uusi Oukari, Mikko ^a   Korpi, Esa R ^c  

^a UNIVERSITY OF TURKU   (Finland)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID ALPHA1 BETA2 GAMMA2 RECEPTOR; 4 AMINOBUTYRIC ACID ALPHA1 BETA2 RECEPTOR; FLUMAZENIL; FUROSEMIDE; NIFLUMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; RECEPTOR SUBTYPE; TERT BUTYLBICYCLOPHOSPHOROTHIOATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BRAIN REGION; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; GABAERGIC TRANSMISSION; GRANULE CELL; LIGAND BINDING; MALE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; RECEPTOR INTRINSIC ACTIVITY; XENOPUS LAEVIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; GABA MODULATORS; GAMMA-AMINOBUTYRIC ACID; MALE; NIFLUMIC ACID; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, GABA-A; XENOPUS LAEVIS;

EID: 0041353559     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.3.753     Document Type: Article

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