Inhibition of hKv2.1, a major human neuronal voltage-gated K+ channel, by meclofenamic acid

European Journal of Pharmacology

Volumn 378, Issue 3, 1999, Pages 349-356

  Lee, Yan T ^a   Wang, Qiang ^a  

^a PFIZER INC   (United States)

Author keywords

hKv2.1; K+ channel, voltage gated; Meclofenamic acid; Nonsteroidal anti inflammatory drug; Ovary cell, Chinese hamster

Indexed keywords

MECLOFENAMIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR;

ARTICLE; CHINESE HAMSTER; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; METHODOLOGY; NONHUMAN; OVARY CELL; PATCH CLAMP; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VOLTAGE CLAMP;

ANIMALS; ANTHRANILIC ACIDS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHO CELLS; CRICETINAE; DELAYED RECTIFIER POTASSIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KINETICS; MECLOFENAMIC ACID; MEMBRANE POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 0032810212     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00485-9     Document Type: Article

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