Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia

BMC Molecular Biology

Volumn 10, Issue , 2009, Pages

  Wu, Jinyong ^a,b   Su, Wen ^a   Jin, Youxin ^c   Shi, Yi ^c   Li, Chune ^a   Zhong, Wenwei ^a   Zhang, Xuehong ^b   Zhang, Zili ^d   Xia, Zhenwei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; HEME OXYGENASE 1; HEMIN; PROTOPORPHYRIN; SMALL INTERFERING RNA; SMALL INTERFERING RNA 4; UNCLASSIFIED DRUG; HEME OXYGENASE; HMOX1 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DOWN REGULATION; DRUG DISTRIBUTION; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE REPRESSION; GENE TARGETING; LIVER; NEWBORN; NEWBORN JAUNDICE; NONHUMAN; RAT; REGULATORY MECHANISM; SPLEEN; ANIMAL; BIOSYNTHESIS; BLOOD; CELL LINE; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HYPERBILIRUBINEMIA; METABOLISM; SPRAGUE DAWLEY RAT; TRANSGENE;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; BILIRUBIN; CELL LINE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE (DECYCLIZING); HEMIN; HYPERBILIRUBINEMIA; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; TRANSGENES;

EID: 68949164667     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-10-77     Document Type: Article

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