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1
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0022553242
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Control of heme metabolism with synthetic metalloporphyrins
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Kappas A, Drummond GS. Control of heme metabolism with synthetic metalloporphyrins. J Clin Invest. 1986;77:335-339
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(1986)
J Clin Invest
, vol.77
, pp. 335-339
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Kappas, A.1
Drummond, G.S.2
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2
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0001490181
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Prevention of neonatal hyperbilirubinemia by Sn-protoporphyrin IX, a potent competitive inhibitor of heme oxidation
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Drummond GS, Kappas A. Prevention of neonatal hyperbilirubinemia by Sn-protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proc Natl Acad Sci USA. 1981;78:6466-6470
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(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 6466-6470
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Drummond, G.S.1
Kappas, A.2
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3
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0020479196
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Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation
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Yoshinaga T, Sassa S, Kappas A. Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation. J Biol Chem. 1982;257:7778-7785
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(1982)
J Biol Chem
, vol.257
, pp. 7778-7785
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Yoshinaga, T.1
Sassa, S.2
Kappas, A.3
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4
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0343877380
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The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin
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Kappas A, Simionatto CS, Drummond GS, Sassa S, Anderson KE. The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin. Proc Natl Acad Sci USA. 1985;82:896-900
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(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 896-900
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Kappas, A.1
Simionatto, C.S.2
Drummond, G.S.3
Sassa, S.4
Anderson, K.E.5
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5
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0012151673
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Dual control mechanism for heme oxygenase: Tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver
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Sardana MK, Kappas A. Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver. Proc Natl Acad Sci USA. 1987;84:2464-2468
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(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2464-2468
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Sardana, M.K.1
Kappas, A.2
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7
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0023654957
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4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism
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4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism. Arch Biochem Biophys. 1987;255:64-74
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(1987)
Arch Biochem Biophys
, vol.255
, pp. 64-74
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Drummond, G.S.1
Galbraith, R.A.2
Sardana, M.K.3
Kappas, A.4
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8
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0023921113
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Photophysical properties of Sn-porphyrins: Potential clinical implications
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Delaney JK, Mauzerall D, Drummond GS, Kappas A. Photophysical properties of Sn-porphyrins: potential clinical implications. Pediatrics. 1988;81:498-504
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(1988)
Pediatrics
, vol.81
, pp. 498-504
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Delaney, J.K.1
Mauzerall, D.2
Drummond, G.S.3
Kappas, A.4
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9
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0023818929
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The use of Sn-protoporphyrin in the management of hyperbilirubinemia in newborn infants with direct Coombs-positive ABO incompatibility
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Kappas A, Drummond GS, Manola T, Petmezaki S, Valaes T. The use of Sn-protoporphyrin in the management of hyperbilirubinemia in newborn infants with direct Coombs-positive ABO incompatibility. Pediatrics. 1988;81:485-497
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(1988)
Pediatrics
, vol.81
, pp. 485-497
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Kappas, A.1
Drummond, G.S.2
Manola, T.3
Petmezaki, S.4
Valaes, T.5
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10
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0023785143
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Sn-protoporphyrin lowers serum bilirubin levels, decreases biliary bilirubin output, enhances biliary heme excretion and potently inhibits hepatic heme oxygenase activity in normal human subjects
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Berglund L, Angelin B, Blomstrand R, Drummond GS, Kappas A. Sn-protoporphyrin lowers serum bilirubin levels, decreases biliary bilirubin output, enhances biliary heme excretion and potently inhibits hepatic heme oxygenase activity in normal human subjects. Hepatology. 1988;8:625-631
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(1988)
Hepatology
, vol.8
, pp. 625-631
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Berglund, L.1
Angelin, B.2
Blomstrand, R.3
Drummond, G.S.4
Kappas, A.5
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11
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0024475062
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Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria
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Galbraith RA, Kappas A. Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria. Hepatology. 1989;9: 882-888
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(1989)
Hepatology
, vol.9
, pp. 882-888
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Galbraith, R.A.1
Kappas, A.2
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12
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0026517719
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Suppression of bilirubin production in the Crigler-Najjar Type I syndrome: Studies with the heme oxygenase inhibitor tin-mesoporphyrin
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Galbraith RA, Drummond GS, Kappas A. Suppression of bilirubin production in the Crigler-Najjar Type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin. Pediatrics. 1992;89:175-182
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(1992)
Pediatrics
, vol.89
, pp. 175-182
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Galbraith, R.A.1
Drummond, G.S.2
Kappas, A.3
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13
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0028069329
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Control of jaundice in preterm newborns by an inhibitor of bilirubin production: Studies with tin-mesoporphyrin
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Valaes T, Petmezaki S, Henschke C, Drummond GS, Kappas A. Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin. Pediatrics. 1994;93:1-11
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(1994)
Pediatrics
, vol.93
, pp. 1-11
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Valaes, T.1
Petmezaki, S.2
Henschke, C.3
Drummond, G.S.4
Kappas, A.5
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14
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0028908103
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Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns
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Kappas A, Drummond GS, Henschke CI, Valaes T. Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns. Pediatrics. 1995;95:468-474
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(1995)
Pediatrics
, vol.95
, pp. 468-474
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Kappas, A.1
Drummond, G.S.2
Henschke, C.I.3
Valaes, T.4
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15
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0031035713
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Zinc porphyrins: Potent inhibitors of hematopoiesis in animal and human bone marrow
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Lutton JD, Abraham NG, Drummond GS, Levere RD, Kappas A. Zinc porphyrins: potent inhibitors of hematopoiesis in animal and human bone marrow. Proc Natl Acad Sci USA. 1997;94:1432-1436
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(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1432-1436
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Lutton, J.D.1
Abraham, N.G.2
Drummond, G.S.3
Levere, R.D.4
Kappas, A.5
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16
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0032064625
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Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin
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Valaes T, Drummond GS, Kappas A. Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin. Pediatrics. 1998;101(5). Available at: http://www.pediatrics.org/cgi/content/full/101/5/e1
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(1998)
Pediatrics
, vol.101
, Issue.5
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Valaes, T.1
Drummond, G.S.2
Kappas, A.3
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17
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0033016231
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Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Sn-mesoporphyrin
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Martinez JC, Garcia HO, Otheguy L, Drummond GS, Kappas A. Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Sn-mesoporphyrin. Pediatrics. 1999;103:1-5
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(1999)
Pediatrics
, vol.103
, pp. 1-5
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Martinez, J.C.1
Garcia, H.O.2
Otheguy, L.3
Drummond, G.S.4
Kappas, A.5
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18
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0034951258
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Single dose of Sn-mesoporphyrin prevents development of significant hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns
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Kappas A, Drummond GS, Valaes TA. Single dose of Sn-mesoporphyrin prevents development of significant hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns. Pediatrics. 2001;108:25-30
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(2001)
Pediatrics
, vol.108
, pp. 25-30
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Kappas, A.1
Drummond, G.S.2
Valaes, T.A.3
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19
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0035194561
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Sn-mesoporphyrin interdiction of severe hyperbilirubinemia in Jehovah's Witness newborns as an alternative to exchange transfusion
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Kappas A, Drummond GS, Munson DP, Marshall JR. Sn-mesoporphyrin interdiction of severe hyperbilirubinemia in Jehovah's Witness newborns as an alternative to exchange transfusion. Pediatrics. 2001;108:1374-1377
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(2001)
Pediatrics
, vol.108
, pp. 1374-1377
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Kappas, A.1
Drummond, G.S.2
Munson, D.P.3
Marshall, J.R.4
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20
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0142184449
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Development of heme oxygenase inhibitors for the prevention of severe jaundice in infants. Studies from laboratory bench to newborn nursery
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Abraham NG, Alam J, Nath KA, eds. Kluwer Academic/Plenum Publishers
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Kappas A. Development of heme oxygenase inhibitors for the prevention of severe jaundice in infants. Studies from laboratory bench to newborn nursery. In Abraham NG, Alam J, Nath KA, eds. Heme Oxygenase in Biology and Medicine. Kluwer Academic/Plenum Publishers; 2002:3-17
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(2002)
Heme Oxygenase in Biology and Medicine
, pp. 3-17
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Kappas, A.1
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