-
1
-
-
0030029427
-
Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?
-
Nicoletti F, Bruno V, Copani A, Casabona G, Knöpfel T (1996) Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? Trends Neurosci 19: 267-271.
-
(1996)
Trends Neurosci
, vol.19
, pp. 267-271
-
-
Nicoletti, F.1
Bruno, V.2
Copani, A.3
Casabona, G.4
Knöpfel, T.5
-
2
-
-
0034852645
-
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs
-
Bruno V, Battaglia G, Copani A, D'Onofrio M, Di Iorio P, et al. (2001) Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. J Cereb Blood Flow Metab 21: 1013-1033.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 1013-1033
-
-
Bruno, V.1
Battaglia, G.2
Copani, A.3
D'Onofrio, M.4
Di Iorio, P.5
-
3
-
-
0025870943
-
Trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) decreases synaptic excitation in rat striatal slices through a presynaptic action
-
Lovinger DM (1991) Trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) decreases synaptic excitation in rat striatal slices through a presynaptic action. Neurosci Lett 129: 17-21.
-
(1991)
Neurosci Lett
, vol.129
, pp. 17-21
-
-
Lovinger, D.M.1
-
4
-
-
0028933282
-
Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3
-
Lovinger DM, McCool BA (1995) Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3. J Neurophysiol 73: 1076-183.
-
(1995)
J Neurophysiol
, vol.73
, pp. 1076-1183
-
-
Lovinger, D.M.1
McCool, B.A.2
-
5
-
-
0030852182
-
In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats
-
Battaglia G, Monn JA, Schoepp DD (1997) In vivo inhibition of veratridine-evoked release of striatal excitatory amino acids by the group II metabotropic glutamate receptor agonist LY354740 in rats. Neurosci Lett 229: 161-164.
-
(1997)
Neurosci Lett
, vol.229
, pp. 161-164
-
-
Battaglia, G.1
Monn, J.A.2
Schoepp, D.D.3
-
6
-
-
0030873754
-
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: In vivo studies with (2S,1'S,2'S,3'R)-2-(2′-carboxy-3′-phenylcyclopropyl)glycine, a new potent and selective antagonist
-
Cozzi A, Attucci S, Peruginelli F, Marinozzi M, Luneia R, et al. (1997) Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2′-carboxy-3′-phenylcyclopropyl)glycine, a new potent and selective antagonist. Eur J Neurosci 9: 1350-1355.
-
(1997)
Eur J Neurosci
, vol.9
, pp. 1350-1355
-
-
Cozzi, A.1
Attucci, S.2
Peruginelli, F.3
Marinozzi, M.4
Luneia, R.5
-
7
-
-
0028912822
-
The metabotropic glutamate receptors: Structure and functions
-
Pin JP, Duvoisin R (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34: 1-26.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1-26
-
-
Pin, J.P.1
Duvoisin, R.2
-
8
-
-
0030901576
-
Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes
-
Sharon D, Vorobiov D, Dascal N (1997) Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes. J Gen Physiol 109: 477-490.
-
(1997)
J Gen Physiol
, vol.109
, pp. 477-490
-
-
Sharon, D.1
Vorobiov, D.2
Dascal, N.3
-
9
-
-
0031032470
-
The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling
-
Bruno V, Sureda FX, Storto M, Casabona G, Caruso A, et al. (1997) The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling. J Neurosci 17: 1891-1897.
-
(1997)
J Neurosci
, vol.17
, pp. 1891-1897
-
-
Bruno, V.1
Sureda, F.X.2
Storto, M.3
Casabona, G.4
Caruso, A.5
-
10
-
-
0032403407
-
Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β
-
Bruno V, Battaglia G, Casabona G, Copani A, Caciagli F, et al. (1998) Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β. J Neurosci 18: 9594-9600.
-
(1998)
J Neurosci
, vol.18
, pp. 9594-9600
-
-
Bruno, V.1
Battaglia, G.2
Casabona, G.3
Copani, A.4
Caciagli, F.5
-
11
-
-
0033198777
-
Activation of A(1) adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100beta protein from cultured astrocytes
-
Ciccarelli R, Di Iorio P, Bruno V, Battaglia G, D'Alimonte I, et al. (1999) Activation of A(1) adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100beta protein from cultured astrocytes. Glia 27: 275-281.
-
(1999)
Glia
, vol.27
, pp. 275-281
-
-
Ciccarelli, R.1
Di Iorio, P.2
Bruno, V.3
Battaglia, G.4
D'Alimonte, I.5
-
12
-
-
17844376201
-
Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways
-
D'Onofrio M, Cuomo L, Battaglia G, Ngomba TR, Storto M, et al. (2001) Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. J Neurochem 78: 435-445.
-
(2001)
J Neurochem
, vol.78
, pp. 435-445
-
-
D'Onofrio, M.1
Cuomo, L.2
Battaglia, G.3
Ngomba, T.R.4
Storto, M.5
-
14
-
-
34547686245
-
The use of knockout mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/ neuroprotection
-
Corti C, Battaglia G, Molinaro G, Riozzi B, Pittaluga A, et al. (2007) The use of knockout mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/ neuroprotection. J Neurosci 27: 8297-308.
-
(2007)
J Neurosci
, vol.27
, pp. 8297-8308
-
-
Corti, C.1
Battaglia, G.2
Molinaro, G.3
Riozzi, B.4
Pittaluga, A.5
-
16
-
-
0037056034
-
DCG-IV but not other group-II metabotropic receptor agonists induces microglial BDNF mRNA expression in the rat striatum. Correlation with neuronal injury
-
Venero JL, Santiago M, Tomas-Camardiel M, Matarredona ER, Cano J, et al. (2002) DCG-IV but not other group-II metabotropic receptor agonists induces microglial BDNF mRNA expression in the rat striatum. Correlation with neuronal injury. Neuroscience 113: 857-869.
-
(2002)
Neuroscience
, vol.113
, pp. 857-869
-
-
Venero, J.L.1
Santiago, M.2
Tomas-Camardiel, M.3
Matarredona, E.R.4
Cano, J.5
-
17
-
-
0037088928
-
Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity
-
Battaglia G, Fornai F, Busceti LC, Aloisi G, Cerrito F, et al. (2002) Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity. J Neurosci 22: 2135-2141.
-
(2002)
J Neurosci
, vol.22
, pp. 2135-2141
-
-
Battaglia, G.1
Fornai, F.2
Busceti, L.C.3
Aloisi, G.4
Cerrito, F.5
-
18
-
-
0037493477
-
Protective role of group-II metabotropic glutamate receptors against nigrostriatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
-
Battaglia G, Busceti LC, Pontarelli F, Fornai F, Paparelli A, et al. (2003) Protective role of group-II metabotropic glutamate receptors against nigrostriatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuropharmacology 45: 155-166.
-
(2003)
Neuropharmacology
, vol.45
, pp. 155-166
-
-
Battaglia, G.1
Busceti, L.C.2
Pontarelli, F.3
Fornai, F.4
Paparelli, A.5
-
19
-
-
0742322858
-
Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
-
Battaglia G, Busceti LC, Molinaro G, Biagioni F, Storto M, et al. (2004) Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. J Neurosci 24: 828-835.
-
(2004)
J Neurosci
, vol.24
, pp. 828-835
-
-
Battaglia, G.1
Busceti, L.C.2
Molinaro, G.3
Biagioni, F.4
Storto, M.5
-
20
-
-
33746233386
-
Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigro-striatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Battaglia G, Busceti CL, Molinaro G, Biagioni F, Traficante F, et al. (2006) Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigro-striatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurosci 26: 7222-7229.
-
(2006)
J Neurosci
, vol.26
, pp. 7222-7229
-
-
Battaglia, G.1
Busceti, C.L.2
Molinaro, G.3
Biagioni, F.4
Traficante, F.5
-
21
-
-
19944430985
-
Protection but maintained dysfunction of nigral dopaminergic nerve cell bodies and striatal dopaminergic terminals in MPTP-lesioned mice after acute treatment with the mGluR5 antagonist MPEP
-
Aguirre JA, Kehr J, Yoshitake T, Liu FL, Rivera A, et al. (2005) Protection but maintained dysfunction of nigral dopaminergic nerve cell bodies and striatal dopaminergic terminals in MPTP-lesioned mice after acute treatment with the mGluR5 antagonist MPEP. Brain Res 1033: 216-220.
-
(2005)
Brain Res
, vol.1033
, pp. 216-220
-
-
Aguirre, J.A.1
Kehr, J.2
Yoshitake, T.3
Liu, F.L.4
Rivera, A.5
-
22
-
-
0027285510
-
GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
-
Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260: 1130-1132.
-
(1993)
Science
, vol.260
, pp. 1130-1132
-
-
Lin, L.F.1
Doherty, D.H.2
Lile, J.D.3
Bektesh, S.4
Collins, F.5
-
23
-
-
0031662603
-
Neuroprotective and neurorestorative properties of GDNF
-
Gash DM, Zhang Z, Gerhardt G (1998) Neuroprotective and neurorestorative properties of GDNF. Ann Neurol 44: S121-S125.
-
(1998)
Ann Neurol
, vol.44
-
-
Gash, D.M.1
Zhang, Z.2
Gerhardt, G.3
-
24
-
-
0037378036
-
In vivo gene delivery of glial cell line-derived neurotrophic factor for Parkinson's disease
-
Kordower JH (2003) In vivo gene delivery of glial cell line-derived neurotrophic factor for Parkinson's disease. Ann Neurol 53: S120-S132.
-
(2003)
Ann Neurol
, vol.53
-
-
Kordower, J.H.1
-
25
-
-
31844440769
-
Assessment in primate models of Parkinson's disease: Comparison with human studies
-
Eslamboli A (2005) Assessment in primate models of Parkinson's disease: comparison with human studies. Rev Neurosci 16: 303-310.
-
(2005)
Rev Neurosci
, vol.16
, pp. 303-310
-
-
Eslamboli, A.1
-
26
-
-
33846501598
-
GDNF family complexes are emerging drug targets
-
Bespalov MM, Saarma M (2007) GDNF family complexes are emerging drug targets. Trends Pharmacol Sci 28: 68-74.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 68-74
-
-
Bespalov, M.M.1
Saarma, M.2
-
27
-
-
33846294812
-
GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-β for its neuroprotective action
-
Schober A, Peterziel H, von Bartheld CS, Simon H, Krieglstein K, et al. (2007) GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-β for its neuroprotective action. Neurobiol Dis 25: 378-91.
-
(2007)
Neurobiol Dis
, vol.25
, pp. 378-391
-
-
Schober, A.1
Peterziel, H.2
von Bartheld, C.S.3
Simon, H.4
Krieglstein, K.5
-
28
-
-
0033602516
-
Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo [3.1.0]hexane-2,6-dicarboxylic acid (LY354740): Identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors
-
Monn JA, Valli MJ, Massey SM, Hansen MM, Kress TJ, et al. (1999) Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo [3.1.0]hexane-2,6-dicarboxylic acid (LY354740): identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors. J Med Chem 42: 1027-1040.
-
(1999)
J Med Chem
, vol.42
, pp. 1027-1040
-
-
Monn, J.A.1
Valli, M.J.2
Massey, S.M.3
Hansen, M.M.4
Kress, T.J.5
-
29
-
-
4043164771
-
The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease
-
Schiefer J, Sprünken A, Puls C, Lüesse HG, Milkereit A, et al. (2004) The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease. Brain Res 1019: 246-254.
-
(2004)
Brain Res
, vol.1019
, pp. 246-254
-
-
Schiefer, J.1
Sprünken, A.2
Puls, C.3
Lüesse, H.G.4
Milkereit, A.5
-
30
-
-
17744369682
-
Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: Reversal by the mGlu(2/3) receptor agonist LY379268
-
Greco B, Invernizzi RW, Carli M (2005) Phencyclidine-induced impairment in attention and response control depends on the background genotype of mice: reversal by the mGlu(2/3) receptor agonist LY379268. Psychopharmacology 179: 68-76.
-
(2005)
Psychopharmacology
, vol.179
, pp. 68-76
-
-
Greco, B.1
Invernizzi, R.W.2
Carli, M.3
-
31
-
-
41949085829
-
Effects of the mGluR2/3 agonist LY379268 and the mGluR5 antagonist MPEP on handling-induced convulsions during ethanol withdrawal in mice
-
Olive MF, Becker HC (2008) Effects of the mGluR2/3 agonist LY379268 and the mGluR5 antagonist MPEP on handling-induced convulsions during ethanol withdrawal in mice. Alcohol 42: 191-197.
-
(2008)
Alcohol
, vol.42
, pp. 191-197
-
-
Olive, M.F.1
Becker, H.C.2
-
32
-
-
51549111390
-
Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain
-
Osikowicz M, Mika J, Makuch W, Przewlocka B (2008) Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain. Pain 139: 117-26.
-
(2008)
Pain
, vol.139
, pp. 117-126
-
-
Osikowicz, M.1
Mika, J.2
Makuch, W.3
Przewlocka, B.4
-
33
-
-
38949207272
-
The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity
-
Woolley ML, Pemberton DJ, Bate S, Corti C, Jones DN (2008) The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity. Psychopharmacology 196: 431-440.
-
(2008)
Psychopharmacology
, vol.196
, pp. 431-440
-
-
Woolley, M.L.1
Pemberton, D.J.2
Bate, S.3
Corti, C.4
Jones, D.N.5
-
34
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
Patil ST, Zhang L, Martenyi F, Lowe SL, Jackson KA, et al. (2007) Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat Med 13: 1102-1107.
-
(2007)
Nat Med
, vol.13
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
-
35
-
-
45749139623
-
Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6- dicarboxylic acid (LY404039)
-
Fell MJ, Svensson KA, Johnson BG, Schoepp DD (2008) Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6- dicarboxylic acid (LY404039). J Pharmacol Exp Ther 326: 209-217.
-
(2008)
J Pharmacol Exp Ther
, vol.326
, pp. 209-217
-
-
Fell, M.J.1
Svensson, K.A.2
Johnson, B.G.3
Schoepp, D.D.4
-
36
-
-
40449139964
-
Identification of a serotonin/glutamate receptor complex implicated in psychosis
-
González-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, et al. (2008) Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature 452: 93-97.
-
(2008)
Nature
, vol.452
, pp. 93-97
-
-
González-Maeso, J.1
Ang, R.L.2
Yuen, T.3
Chan, P.4
Weisstaub, N.V.5
-
37
-
-
0028096652
-
Glial cell-line derived neurotrophic factor (GDNF) mRNA upregulation in striatum and cortical areas after pilocarpine-induced status epilepticus in rats
-
Schmidt-Kastner R, Tomac A, Hoffer B, Bektesh S, Rosenzweig B, et al. (1994) Glial cell-line derived neurotrophic factor (GDNF) mRNA upregulation in striatum and cortical areas after pilocarpine-induced status epilepticus in rats. Brain Res Mol Brain Res 26: 325-330.
-
(1994)
Brain Res Mol Brain Res
, vol.26
, pp. 325-330
-
-
Schmidt-Kastner, R.1
Tomac, A.2
Hoffer, B.3
Bektesh, S.4
Rosenzweig, B.5
-
38
-
-
0029801527
-
Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system
-
Nosrat CA, Tomac A, Lindqvist E, Lindskog S, Humpel C, et al. (1996) Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system. Cell Tissue Res 286: 191-207.
-
(1996)
Cell Tissue Res
, vol.286
, pp. 191-207
-
-
Nosrat, C.A.1
Tomac, A.2
Lindqvist, E.3
Lindskog, S.4
Humpel, C.5
-
39
-
-
0032834028
-
Pharmacological agents acting at subtypes of metabotropic glutamate receptors
-
Schoepp DD, Jane DE, Monn JA (1999) Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38: 1431-1476.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1431-1476
-
-
Schoepp, D.D.1
Jane, D.E.2
Monn, J.A.3
-
40
-
-
0036581222
-
The GDNF family: Signalling, biological functions and therapeutic value
-
Airaksinen MS, Saarma M (2002) The GDNF family: signalling, biological functions and therapeutic value. Nat Rev Neurosci 3: 383-394.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 383-394
-
-
Airaksinen, M.S.1
Saarma, M.2
-
41
-
-
0033559397
-
Glial cell line-derived neurotrophic factor rescues target-deprived sympathetic spinal cord neurons but requires transforming growth factor-b as cofactor in vivo
-
Schober A, Hertel R, Arumae U, Farkas L, Jaszai J, et al. (1999) Glial cell line-derived neurotrophic factor rescues target-deprived sympathetic spinal cord neurons but requires transforming growth factor-b as cofactor in vivo. J Neurosci 19: 2008-2015.
-
(1999)
J Neurosci
, vol.19
, pp. 2008-2015
-
-
Schober, A.1
Hertel, R.2
Arumae, U.3
Farkas, L.4
Jaszai, J.5
-
42
-
-
0028170589
-
TGF beta 2 and TGF beta 3 are potent survival factors for midbrain dopaminergic neurons
-
Poulsen KT, Armanini MP, Klein RD, Hynes MA, Phillips HS, et al. (1994) TGF beta 2 and TGF beta 3 are potent survival factors for midbrain dopaminergic neurons. Neuron 13: 1245-1252.
-
(1994)
Neuron
, vol.13
, pp. 1245-1252
-
-
Poulsen, K.T.1
Armanini, M.P.2
Klein, R.D.3
Hynes, M.A.4
Phillips, H.S.5
-
43
-
-
0032850453
-
Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease
-
Kordower JH, Palfi S, Chen EY, Ma SY, Sendera T, et al. (1999) Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann Neurol 46: 419-424.
-
(1999)
Ann Neurol
, vol.46
, pp. 419-424
-
-
Kordower, J.H.1
Palfi, S.2
Chen, E.Y.3
Ma, S.Y.4
Sendera, T.5
-
44
-
-
0038249170
-
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill SS, Patel NK, Hotton GR, O'Sullivan K, McCarter R, et al. (2003) Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 9: 589-595.
-
(2003)
Nat Med
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
O'Sullivan, K.4
McCarter, R.5
-
45
-
-
14844311296
-
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
-
Slevin JT, Gerhardt GA, Smith CD, Gash DM, Kryscio R, et al. (2005) Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 102: 216-222.
-
(2005)
J Neurosurg
, vol.102
, pp. 216-222
-
-
Slevin, J.T.1
Gerhardt, G.A.2
Smith, C.D.3
Gash, D.M.4
Kryscio, R.5
-
46
-
-
33644833272
-
Randomized controlled trial of intraputamenal glial cell line-derived growth factor infusion in Parkinson's disease
-
Lang AE, Gill S, Patel NK, Lozano A, Nutt JG, et al. (2006) Randomized controlled trial of intraputamenal glial cell line-derived growth factor infusion in Parkinson's disease. Ann Neurol 59: 459-466.
-
(2006)
Ann Neurol
, vol.59
, pp. 459-466
-
-
Lang, A.E.1
Gill, S.2
Patel, N.K.3
Lozano, A.4
Nutt, J.G.5
-
47
-
-
46749109164
-
PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease
-
Visanji NP, Orsi A, Johnston TH, Howson PA, Dixon K, et al. (2008) PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. FASEB J 22: 2488-2497.
-
(2008)
FASEB J
, vol.22
, pp. 2488-2497
-
-
Visanji, N.P.1
Orsi, A.2
Johnston, T.H.3
Howson, P.A.4
Dixon, K.5
-
48
-
-
34548721105
-
Rasagiline promotes regeneration of substantia nigra dopaminergic neurons in post-MPTP-induced Parkinsonism via activation of tyrosine kinase receptor signaling pathway
-
Mandel SA, Sagi Y, Amit T (2007) Rasagiline promotes regeneration of substantia nigra dopaminergic neurons in post-MPTP-induced Parkinsonism via activation of tyrosine kinase receptor signaling pathway. Neurochem Res 32: 1694-1699.
-
(2007)
Neurochem Res
, vol.32
, pp. 1694-1699
-
-
Mandel, S.A.1
Sagi, Y.2
Amit, T.3
-
49
-
-
37049015753
-
Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: New insights and implications for therapy
-
Weinreb O, Amit T, Bar-Am O, Youdim MB (2007) Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. Ann N Y Acad Sci 1122: 155-168.
-
(2007)
Ann N Y Acad Sci
, vol.1122
, pp. 155-168
-
-
Weinreb, O.1
Amit, T.2
Bar-Am, O.3
Youdim, M.B.4
-
50
-
-
0031689603
-
LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats
-
Konieczny J, Ossowska K, Wolfarth S, Pilc A (1998) LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats. Naunyn Schmiedebergs Arch Pharmacol 358: 500-502.
-
(1998)
Naunyn Schmiedebergs Arch Pharmacol
, vol.358
, pp. 500-502
-
-
Konieczny, J.1
Ossowska, K.2
Wolfarth, S.3
Pilc, A.4
-
51
-
-
0033967160
-
The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat
-
Dawson L, Chadha A, Megalou M, Duty S (2000) The group II metabotropic glutamate receptor agonist, DCG-IV, alleviates akinesia following intranigral or intraventricular administration in the reserpine-treated rat. Br J Pharmacol 129: 541-546.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 541-546
-
-
Dawson, L.1
Chadha, A.2
Megalou, M.3
Duty, S.4
-
52
-
-
9344255435
-
Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2
-
Yokoi M, Kobayashi K, Manabe T, Takahashi T, Sakaguchi I, et al. (1996) Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2. Science 273: 645-647.
-
(1996)
Science
, vol.273
, pp. 645-647
-
-
Yokoi, M.1
Kobayashi, K.2
Manabe, T.3
Takahashi, T.4
Sakaguchi, I.5
-
53
-
-
68949095864
-
-
Rose K, Goldberg MP, Choi DW (1992) Cytotoxicity in murine neocortical cell cultures. In: Tyson CA, Frazier JM, eds. Methods in toxicology, 1, In Vitro Biological System. San Diego: San Diego Academics. pp 46-60.
-
Rose K, Goldberg MP, Choi DW (1992) Cytotoxicity in murine neocortical cell cultures. In: Tyson CA, Frazier JM, eds. Methods in toxicology, Vol. 1, In Vitro Biological System. San Diego: San Diego Academics. pp 46-60.
-
-
-
-
55
-
-
0030915959
-
Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS
-
Trupp M, Belluardo N, Funakoshi H, Ibanez CF (1997) Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. J Neurosci 17: 3554-3567.
-
(1997)
J Neurosci
, vol.17
, pp. 3554-3567
-
-
Trupp, M.1
Belluardo, N.2
Funakoshi, H.3
Ibanez, C.F.4
-
56
-
-
68949100727
-
-
Lehmann A. Atlas stereotaxique du cerveau de la souris. Ed. Du centre National de la recherche, Paris, 1974.
-
Lehmann A. Atlas stereotaxique du cerveau de la souris. Ed. Du centre National de la recherche, Paris, 1974.
-
-
-
-
57
-
-
20444401182
-
Transcription factor gene expression profiling after acute intermittent nicotine treatment in the rat cerebral cortex
-
Belluardo N, Olsson PA, Mudo' G, Sommer WH, Amato G, et al. (2005) Transcription factor gene expression profiling after acute intermittent nicotine treatment in the rat cerebral cortex. Neuroscience 133: 787-796.
-
(2005)
Neuroscience
, vol.133
, pp. 787-796
-
-
Belluardo, N.1
Olsson, P.A.2
Mudo', G.3
Sommer, W.H.4
Amato, G.5
-
58
-
-
0023760665
-
The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
-
Gundersen HJG, Bagger P, Bendtsen TF, Evans SM, Korbo L, et al. (1988) The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. Acta Pathol Microbiol Immunol Scand 96: 857-881.
-
(1988)
Acta Pathol Microbiol Immunol Scand
, vol.96
, pp. 857-881
-
-
Gundersen, H.J.G.1
Bagger, P.2
Bendtsen, T.F.3
Evans, S.M.4
Korbo, L.5
-
59
-
-
0033045425
-
The efficiency of systematic sampling in stereology: Reconsidered
-
Gundersen HJG, Jensen EB, Kiâu K, Nielsen J (1999) The efficiency of systematic sampling in stereology: reconsidered. J Microsc 193: 199-211.
-
(1999)
J Microsc
, vol.193
, pp. 199-211
-
-
Gundersen, H.J.G.1
Jensen, E.B.2
Kiâu, K.3
Nielsen, J.4
-
60
-
-
0023950504
-
Total number of neurons and glial cells in human brain nuclei estimated by disector and fractionator
-
Pakkenberg B, Gundersen HJG (1988) Total number of neurons and glial cells in human brain nuclei estimated by disector and fractionator. J Microsc 150: 1-20.
-
(1988)
J Microsc
, vol.150
, pp. 1-20
-
-
Pakkenberg, B.1
Gundersen, H.J.G.2
-
61
-
-
0029968229
-
If you assume, you can make an ass out of u and me: A decade of the dissector for stereological counting of particles in 3D space
-
Mayhew TM, Gundersen HJG (1996) "If you assume, you can make an ass out of u and me": a decade of the dissector for stereological counting of particles in 3D space. J Anat 188: 1-15.
-
(1996)
J Anat
, vol.188
, pp. 1-15
-
-
Mayhew, T.M.1
Gundersen, H.J.G.2
|