-
1
-
-
10744231300
-
The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. European Network for Understanding Mechanisms of Severe Asthma
-
The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. European Network for Understanding Mechanisms of Severe Asthma. Eur Respir J 2003, 22:470-477.
-
(2003)
Eur Respir J
, vol.22
, pp. 470-477
-
-
-
2
-
-
0034526865
-
Proceedings of the ATS workshop on refractory asthma: Current understanding, recommendations, and unanswered questions. American Thoracic Society
-
Proceedings of the ATS workshop on refractory asthma: Current understanding, recommendations, and unanswered questions. American Thoracic Society. Am J Respir Crit Care Med 2000, 162:2341-2351.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2341-2351
-
-
-
3
-
-
9144268928
-
Design and baseline characteristics of The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study: A large cohort of patients with severe or difficult-to-treat asthma
-
Dolan CM, Fraher KE, Bleecker ER, et al.: Design and baseline characteristics of The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study: A large cohort of patients with severe or difficult-to-treat asthma. Ann Allergy Asthma Immunol 2004, 92:32-39.
-
(2004)
Ann Allergy Asthma Immunol
, vol.92
, pp. 32-39
-
-
Dolan, C.M.1
Fraher, K.E.2
Bleecker, E.R.3
-
4
-
-
0033025989
-
Difficult/therapy-resistant asthma: The need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/ Therapy-Resistant Asthma. European Respiratory Society
-
Chung KF, Godard P, Adelroth E, et al.: Difficult/therapy-resistant asthma: The need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society. Eur Respir J 1999, 13:1198-1208.
-
(1999)
Eur Respir J
, vol.13
, pp. 1198-1208
-
-
Chung, K.F.1
Godard, P.2
Adelroth, E.3
-
5
-
-
33846017302
-
Severe asthma: Lessons from the Severe Asthma Research Program
-
the National Heart, Lung, and Blood Institute's Severe Asthma Research Program: quiz 22-23
-
Wenzel SE, Busse WW; the National Heart, Lung, and Blood Institute's Severe AsLhma Research Program: Severe asthma: lessons from the Severe Asthma Research Program. J Allergy Clin Immunol 2007, 119:14-21; quiz 22-23.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 14-21
-
-
Wenzel, S.E.1
Busse, W.W.2
-
6
-
-
53049084809
-
A new perspective on concepts of asthma severity and control
-
Taylor DR, Bateman ED, Boulet LP, et al.: A new perspective on concepts of asthma severity and control. Eur Respir J 2008, 32:545-554.
-
(2008)
Eur Respir J
, vol.32
, pp. 545-554
-
-
Taylor, D.R.1
Bateman, E.D.2
Boulet, L.P.3
-
7
-
-
5144221336
-
Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma Control study
-
Bateman ED, Boushey HA, Bousquet J, et al.: Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma Control study. Am J Respir Crit Care Med 2004, 170:836-844.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 836-844
-
-
Bateman, E.D.1
Boushey, H.A.2
Bousquet, J.3
-
8
-
-
0038015441
-
Predictors of therapy resistant asthma: Outcome of a systematic evaluation protocol
-
Heaney LG, Conway E, Kelly C, et al.: Predictors of therapy resistant asthma: Outcome of a systematic evaluation protocol. Thorax 2003, 58:561-566.
-
(2003)
Thorax
, vol.58
, pp. 561-566
-
-
Heaney, L.G.1
Conway, E.2
Kelly, C.3
-
9
-
-
10744224453
-
Systematic assessment of difficult-to-treat asthma
-
Robinson DS, Campbell DA, Durham SR, et al.: Systematic assessment of difficult-to-treat asthma. Eur Respir J 2003, 22:478-483.
-
(2003)
Eur Respir J
, vol.22
, pp. 478-483
-
-
Robinson, D.S.1
Campbell, D.A.2
Durham, S.R.3
-
10
-
-
33544462016
-
Relationship between adherence to prescribed regimens and asthma control in patients with difficult asthma
-
Aburuz S, McElnay J, Millership J, et al.: Relationship between adherence to prescribed regimens and asthma control in patients with difficult asthma. Thorax 2002, 57(Suppl III):iIi89.
-
(2002)
Thorax
, vol.57
, Issue.SUPPL. III
-
-
Aburuz, S.1
McElnay, J.2
Millership, J.3
-
11
-
-
4444246466
-
Relationship between asthma severity and obesity
-
Akerman MJ, Calacanis CM, Madsen MK: Relationship between asthma severity and obesity. J Asthma 2004, 41:521-526.
-
(2004)
J Asthma
, vol.41
, pp. 521-526
-
-
Akerman, M.J.1
Calacanis, C.M.2
Madsen, M.K.3
-
12
-
-
33644885777
-
Are overweight asthmatics more difficult to control?
-
Saint-Pierre P, Bourdin A, Chanez P, et al.: Are overweight asthmatics more difficult to control? Allergy 2006, 61:79-84.
-
(2006)
Allergy
, vol.61
, pp. 79-84
-
-
Saint-Pierre, P.1
Bourdin, A.2
Chanez, P.3
-
13
-
-
13544254381
-
Epidemiological Study on the Genetics and Environment of Asthma: Asthma severity is associated with body mass index and early menarche in women
-
Varraso R, Siroux V, Maccario J, et al.: Epidemiological Study on the Genetics and Environment of Asthma: Asthma severity is associated with body mass index and early menarche in women. Am J Respir Crit Care Med 2005, 171:334-339.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 334-339
-
-
Varraso, R.1
Siroux, V.2
Maccario, J.3
-
14
-
-
58249086394
-
Effect of weight change on asthma-related health outcomes in patients with severe or difficult-to-treat asthma
-
Haselkorn T, Fish JE, Chipps BE, et al.: Effect of weight change on asthma-related health outcomes in patients with severe or difficult-to-treat asthma. Respir Med 2009, 103:274-283.
-
(2009)
Respir Med
, vol.103
, pp. 274-283
-
-
Haselkorn, T.1
Fish, J.E.2
Chipps, B.E.3
-
15
-
-
41749115987
-
Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
-
van Veen IH, Ten Brinke A, Sterk PJ, et al.: Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. Allergy 2008, 63:570-574.
-
(2008)
Allergy
, vol.63
, pp. 570-574
-
-
van Veen, I.H.1
Ten Brinke, A.2
Sterk, P.J.3
-
16
-
-
2942733178
-
Effect of weight reduction on respiratory function and airway reactivity in obese women
-
Aaron SD, Fergusson D, Dent R, et al.: Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest 2004, 125:2046-2052.
-
(2004)
Chest
, vol.125
, pp. 2046-2052
-
-
Aaron, S.D.1
Fergusson, D.2
Dent, R.3
-
17
-
-
0033728998
-
Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma
-
Hakala K, Stenius-Aarniala B, Sovijarvi A: Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma. Chest 2000, 118:1315-1321.
-
(2000)
Chest
, vol.118
, pp. 1315-1321
-
-
Hakala, K.1
Stenius-Aarniala, B.2
Sovijarvi, A.3
-
19
-
-
37549020054
-
Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: Insights from the TENOR study
-
Lee JH, Haselkorn T, Borish L, et al.: Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: insights from the TENOR study. Chest 2007, 132:1882-1889.
-
(2007)
Chest
, vol.132
, pp. 1882-1889
-
-
Lee, J.H.1
Haselkorn, T.2
Borish, L.3
-
20
-
-
33745742455
-
Effects of smoking cessation on lung function and airway inflammation in smokers with asthma
-
Chaudhuri R, Livingston E, McMahon AD, et al.: Effects of smoking cessation on lung function and airway inflammation in smokers with asthma. Am J Respir Crit Care Med 2006, 174:127-133.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 127-133
-
-
Chaudhuri, R.1
Livingston, E.2
McMahon, A.D.3
-
21
-
-
0036187872
-
Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma
-
Chalmers GW, Macleod KJ, Little SA, et al.: Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma. Thorax 2002, 57:226-230.
-
(2002)
Thorax
, vol.57
, pp. 226-230
-
-
Chalmers, G.W.1
Macleod, K.J.2
Little, S.A.3
-
22
-
-
0242537115
-
Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma
-
Chaudhuri R, Livingston E, McMahon AD, et al.: Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma. Am J Respir Crit Care Med 2003, 168:1308-1311.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1308-1311
-
-
Chaudhuri, R.1
Livingston, E.2
McMahon, A.D.3
-
23
-
-
0029985810
-
Eosinophil and neutrophil activity in asthma in a one-year trial with inhaled budesonide. The impact of smoking
-
Pedersen B, Dahl R, Karlstrom R, et al.: Eosinophil and neutrophil activity in asthma in a one-year trial with inhaled budesonide. The impact of smoking. Am J Respir Crit Care Med 1996, 153:1519-1529.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 1519-1529
-
-
Pedersen, B.1
Dahl, R.2
Karlstrom, R.3
-
24
-
-
0035060089
-
Similar psychological characteristics in mild and severe asthma
-
ten Brinke A, Ouwerkerk ME, Bel EH, Spinhoven P: Similar psychological characteristics in mild and severe asthma. J Psychosom Res 2001, 50:7-10.
-
(2001)
J Psychosom Res
, vol.50
, pp. 7-10
-
-
ten Brinke, A.1
Ouwerkerk, M.E.2
Bel, E.H.3
Spinhoven, P.4
-
25
-
-
0028910350
-
Psychiatric and medical features of near fatal asthma
-
Campbell DA, Yellowlees PM, McLennan G, et al.: Psychiatric and medical features of near fatal asthma. Thorax 1995, 50:254-259.
-
(1995)
Thorax
, vol.50
, pp. 254-259
-
-
Campbell, D.A.1
Yellowlees, P.M.2
McLennan, G.3
-
26
-
-
0030801354
-
Psychological morbidity and coping skills in patients with brittle and non-brittle asthma: A case-control study
-
Miles JF, Garden GM, Tunnicliffe WS, et al.: Psychological morbidity and coping skills in patients with brittle and non-brittle asthma: A case-control study. Clin Exp Allergy 1997, 27:1151-1159.
-
(1997)
Clin Exp Allergy
, vol.27
, pp. 1151-1159
-
-
Miles, J.F.1
Garden, G.M.2
Tunnicliffe, W.S.3
-
27
-
-
0036221632
-
Case-control study of severe life threatening asthma (SLTA) in adults: Psychological factors
-
Kolbe J, Fergusson W, Vamos M, Garrett J: Case-control study of severe life threatening asthma (SLTA) in adults: Psychological factors. Thorax 2002, 57:317-322.
-
(2002)
Thorax
, vol.57
, pp. 317-322
-
-
Kolbe, J.1
Fergusson, W.2
Vamos, M.3
Garrett, J.4
-
28
-
-
0035028702
-
Psychopathology in patients with severe asthma is associated with increased health care utilization
-
ten Brinke A, Ouwerkerk ME, Zwinderman AH, et al.: Psychopathology in patients with severe asthma is associated with increased health care utilization. Am J Respir Crit Care Med 2001, 163:1093-1096.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 1093-1096
-
-
ten Brinke, A.1
Ouwerkerk, M.E.2
Zwinderman, A.H.3
-
29
-
-
23344451854
-
Prevalence of psychiatric morbidity in a difficult asthma population: Relationship to asthma outcome
-
Heaney LG, Conway E, Kelly C, Gamble J: Prevalence of psychiatric morbidity in a difficult asthma population: Relationship to asthma outcome. Respir Med 2005, 99:1152-1159.
-
(2005)
Respir Med
, vol.99
, pp. 1152-1159
-
-
Heaney, L.G.1
Conway, E.2
Kelly, C.3
Gamble, J.4
-
30
-
-
19044391020
-
Prevalence of gastroesophageal reflux in difficult asthma: Relationship to asthma outcome
-
Leggett JJ, Johnston BT, Mills M, et al.: Prevalence of gastroesophageal reflux in difficult asthma: Relationship to asthma outcome. Chest 2005, 127:1227-1231.
-
(2005)
Chest
, vol.127
, pp. 1227-1231
-
-
Leggett, J.J.1
Johnston, B.T.2
Mills, M.3
-
32
-
-
41749101535
-
Lack of control of severe asthma is associated with co-existence of moderate-to-severe rhinitis
-
Ponte EV, Franco R, Nascimento HF, et al.: Lack of control of severe asthma is associated with co-existence of moderate-to-severe rhinitis. Allergy 2008, 63:564-569.
-
(2008)
Allergy
, vol.63
, pp. 564-569
-
-
Ponte, E.V.1
Franco, R.2
Nascimento, H.F.3
-
33
-
-
64349113168
-
Efficacy of esomeprazole for treatment of poorly controlled asthma: A randomized controlled trial
-
Mastronarde JG, Anthonisen NR, Castro M, et al.: Efficacy of esomeprazole for treatment of poorly controlled asthma: A randomized controlled trial. N Engl J Med 2009, 360:1487-1499.
-
(2009)
N Engl J Med
, vol.360
, pp. 1487-1499
-
-
Mastronarde, J.G.1
Anthonisen, N.R.2
Castro, M.3
-
35
-
-
34247485053
-
Noneosinophilic asthma: A distinct clinical and pathologic phenotype
-
quiz 1053-1054
-
Haldar P, Pavord IA: Noneosinophilic asthma: a distinct clinical and pathologic phenotype. J Allergy Clin Immunol 2007, 119:1043-1052; quiz 1053-1054.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 1043-1052
-
-
Haldar, P.1
Pavord, I.D.2
-
36
-
-
0032875377
-
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
-
Wenzel SE, Schwartz LB, Langmack EL, et al.: Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999, 160:1001-1008.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1001-1008
-
-
Wenzel, S.E.1
Schwartz, L.B.2
Langmack, E.L.3
-
37
-
-
0346041503
-
Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation
-
Miranda C, Busacker A, Balzar S, et al.: Distinguishing severe asthma phenotypes: Role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 2004, 113:101-108.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 101-108
-
-
Miranda, C.1
Busacker, A.2
Balzar, S.3
-
38
-
-
0035447569
-
Factors associated with persistent airflow limitation in severe asthma
-
ten Brinke A, Zwinderman AH, Sterk PJ, et al.: Factors associated with persistent airflow limitation in severe asthma. Am J Respir Crit Care Med 2001, 164:744-748.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 744-748
-
-
ten Brinke, A.1
Zwinderman, A.H.2
Sterk, P.J.3
-
39
-
-
4444221246
-
"Refractory" eosinophilic airway inflammation in severe asthma: Effect of parenteral corticosteroids
-
ten Brinke A, Zwinderman AH, Sterk PJ, et al.: "Refractory" eosinophilic airway inflammation in severe asthma: Effect of parenteral corticosteroids. Am J Respir Crit Care Med 2004, 170:601-605.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 601-605
-
-
ten Brinke, A.1
Zwinderman, A.H.2
Sterk, P.J.3
-
40
-
-
33646475553
-
Ciclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthma
-
Bateman E, Karpel J, Casale T, et al.: Ciclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthma. Chest 2006, 129:1176-1187.
-
(2006)
Chest
, vol.129
, pp. 1176-1187
-
-
Bateman, E.1
Karpel, J.2
Casale, T.3
-
41
-
-
52049113214
-
New targets for drug development in asthma
-
Adcock IM, Caramori G, Chung KF: New targets for drug development in asthma. Lancet 2008, 372:1073-1087.
-
(2008)
Lancet
, vol.372
, pp. 1073-1087
-
-
Adcock, I.M.1
Caramori, G.2
Chung, K.F.3
-
42
-
-
30444452988
-
Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size
-
Usmani OS, Biddiscombe MF, Barnes PJ: Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size. Am J Respir Crit Care Med 2005, 172:1497-1504.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 1497-1504
-
-
Usmani, O.S.1
Biddiscombe, M.F.2
Barnes, P.J.3
-
43
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
-
Green RH, Brightling CE, McKenna S, et al.: Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial. Lancet 2002, 360:1715-1721.
-
(2002)
Lancet
, vol.360
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
-
44
-
-
28444470826
-
Exhaled nitric oxide identifies the persistent eosinophilic phenotype in severe refractory asthma
-
Silkoff PE, Lent AM, Busacker AA, et al.: Exhaled nitric oxide identifies the persistent eosinophilic phenotype in severe refractory asthma. J Allergy Clin Immunol 2005, 116:1249-1255.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 1249-1255
-
-
Silkoff, P.E.1
Lent, A.M.2
Busacker, A.A.3
-
45
-
-
33646264353
-
Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma
-
van Veen IH, Sterk PJ, Schot R, et al.: Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma. Eur Respir J 2006, 27:951-956.
-
(2006)
Eur Respir J
, vol.27
, pp. 951-956
-
-
van Veen, I.H.1
Sterk, P.J.2
Schot, R.3
-
46
-
-
20444506757
-
Alveolar nitric oxide in adults with asthma: Evidence of distal lung inflammation in refractory asthma
-
Berry M, Hargadon B, Morgan A, et al.: Alveolar nitric oxide in adults with asthma: Evidence of distal lung inflammation in refractory asthma. Eur Respir J 2005, 25:986-991.
-
(2005)
Eur Respir J
, vol.25
, pp. 986-991
-
-
Berry, M.1
Hargadon, B.2
Morgan, A.3
-
47
-
-
58849138317
-
The response to combination therapy treatment regimens in severe/ difficult-to-treat asthma
-
Campbell JD, Borish L, Haselkorn T, et al.: The response to combination therapy treatment regimens in severe/difficult-to-treat asthma. Eur Respir J 2008, 32:1237-1242.
-
(2008)
Eur Respir J
, vol.32
, pp. 1237-1242
-
-
Campbell, J.D.1
Borish, L.2
Haselkorn, T.3
-
48
-
-
33645116037
-
Low sputum eosinophils predict the lack of response to beclomethasone in symptomatic asthmatic patients
-
Bacci E, Cianchetti S, Bartoli M, et al.: Low sputum eosinophils predict the lack of response to beclomethasone in symptomatic asthmatic patients. Chest 2006, 129:565-572.
-
(2006)
Chest
, vol.129
, pp. 565-572
-
-
Bacci, E.1
Cianchetti, S.2
Bartoli, M.3
-
49
-
-
0036795111
-
Analysis of induced sputum in adults with asthma: Identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
-
Green RH, Brightling CE, Woltmann G, et al.: Analysis of induced sputum in adults with asthma: Identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax 2002, 57:875-879.
-
(2002)
Thorax
, vol.57
, pp. 875-879
-
-
Green, R.H.1
Brightling, C.E.2
Woltmann, G.3
-
50
-
-
0033606539
-
Non-eosinophilic corticosteroid unresponsive asthma
-
Pavord ID, Brightling CE, Woltmann G, Wardlaw AJ: Non-eosinophilic corticosteroid unresponsive asthma. Lancet 1999, 353:2213-2214.
-
(1999)
Lancet
, vol.353
, pp. 2213-2214
-
-
Pavord, I.D.1
Brightling, C.E.2
Woltmann, G.3
Wardlaw, A.J.4
-
51
-
-
18644373492
-
Clinical use of noninvasive measurements of airway inflammation in steroid reduction in children
-
Zacharasiewicz A, Wilson N, Lex C, et al.: Clinical use of noninvasive measurements of airway inflammation in steroid reduction in children. Am J Respir Crit Care Med 2005, 171:1077-1082.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1077-1082
-
-
Zacharasiewicz, A.1
Wilson, N.2
Lex, C.3
-
52
-
-
0031911619
-
Relationship between airway obstruction and respiratory symptoms in adult asthmatics
-
Teeter JG, Bleecker ER: Relationship between airway obstruction and respiratory symptoms in adult asthmatics. Chest 1998, 113:272-277.
-
(1998)
Chest
, vol.113
, pp. 272-277
-
-
Teeter, J.G.1
Bleecker, E.R.2
-
54
-
-
0033940777
-
Relationship between increased airway responsiveness and asthma severity in the childhood asthma management program
-
Weiss ST, Van Natta ML, Zeiger RS: Relationship between increased airway responsiveness and asthma severity in the childhood asthma management program. Am J Respir Crit Care Med 2000, 162:50-56.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 50-56
-
-
Weiss, S.T.1
Van Natta, M.L.2
Zeiger, R.S.3
-
55
-
-
0024416164
-
Nonspecific bronchial reactivity and its relationship to the clinical expression of asthma. A longitudinal study
-
Josephs LK, Gregg I, Mullee MA, Holgate ST: Nonspecific bronchial reactivity and its relationship to the clinical expression of asthma. A longitudinal study. Am Rev Respir Dis 1989, 140:350-357.
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 350-357
-
-
Josephs, L.K.1
Gregg, I.2
Mullee, M.A.3
Holgate, S.T.4
-
56
-
-
0021273449
-
The shape of the dose-response curve to histamine in asthmatic and normal subjects
-
Woolcock AJ, Salome CM, Yan K: The shape of the dose-response curve to histamine in asthmatic and normal subjects. Am Rev Respir Dis 1984, 130:71-75.
-
(1984)
Am Rev Respir Dis
, vol.130
, pp. 71-75
-
-
Woolcock, A.J.1
Salome, C.M.2
Yan, K.3
-
57
-
-
0034882519
-
A new asthma severity index: A predictor of near-fatal asthma?
-
Lee P, Abisheganaden J,AChee CB, Wang YT: A new asthma severity index: a predictor of near-fatal asthma? Eur Respir J 2001, 18:272-278.
-
(2001)
Eur Respir J
, vol.18
, pp. 272-278
-
-
Lee, P.1
Abisheganaden, J.2
Chee, C.B.3
Wang, Y.T.4
-
58
-
-
0033694849
-
Unsuspected pseudophysiologic emphysema in chronic persistent asthma
-
Gelb AF, Zamel N: Unsuspected pseudophysiologic emphysema in chronic persistent asthma. Am J Respir Crit Care Med 2000, 162:1778-1782.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1778-1782
-
-
Gelb, A.F.1
Zamel, N.2
-
59
-
-
6344263883
-
Risk factors for near-fatal asthma
-
Gelb AF, Schein A, Nussbaum E, et al.: Risk factors for near-fatal asthma. Chest 2004, 126:1138-1146.
-
(2004)
Chest
, vol.126
, pp. 1138-1146
-
-
Gelb, A.F.1
Schein, A.2
Nussbaum, E.3
-
60
-
-
5144221335
-
Abnormal alveolar attachments with decreased elastic fiber content in distal lung in fatal asthma
-
Mauad T, Silva LF, Santos MA, et al.: Abnormal alveolar attachments with decreased elastic fiber content in distal lung in fatal asthma. Am J Respir Crit Care Med 2004, 170:857-862.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 857-862
-
-
Mauad, T.1
Silva, L.F.2
Santos, M.A.3
-
61
-
-
0034131479
-
Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes
-
in't Veen JC, Beekman AJ, Bel EH, Sterk PJ: Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. Am J Respir Crit Care Med 2000, 161:1902-1906.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1902-1906
-
-
in't Veen, J.C.1
Beekman, A.J.2
Bel, E.H.3
Sterk, P.J.4
-
62
-
-
3543146737
-
Parameters associated with persistent airflow obstruction in chronic severe asthma
-
Bumbacea D, Campbell D, Nguyen L, et al.: Parameters associated with persistent airflow obstruction in chronic severe asthma. Eur Respir J 2004, 24:122-128.
-
(2004)
Eur Respir J
, vol.24
, pp. 122-128
-
-
Bumbacea, D.1
Campbell, D.2
Nguyen, L.3
-
64
-
-
20044362008
-
Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE
-
Humbert M, Beasley R, Ayres J, et al.: Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy 2005, 60:309-316.
-
(2005)
Allergy
, vol.60
, pp. 309-316
-
-
Humbert, M.1
Beasley, R.2
Ayres, J.3
-
65
-
-
20044368243
-
The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma
-
Bousquet J, Cabrera P, Berkman N, et al.: The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma. Allergy 2005, 60:302-308.
-
(2005)
Allergy
, vol.60
, pp. 302-308
-
-
Bousquet, J.1
Cabrera, P.2
Berkman, N.3
-
66
-
-
32644447957
-
The link between fungi and severe asthma: A summary of the evidence
-
Denning DW, O'Driscoll BR, Hogaboam CM, et al.: The link between fungi and severe asthma: A summary of the evidence. Eur Respir J 2006, 27:615-626.
-
(2006)
Eur Respir J
, vol.27
, pp. 615-626
-
-
Denning, D.W.1
O'Driscoll, B.R.2
Hogaboam, C.M.3
-
67
-
-
58349115630
-
Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study
-
Denning DW, O'Driscoll BR, Powell G, et al.: Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study. Am J Respir Crit Care Med 2009, 179:11-18.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 11-18
-
-
Denning, D.W.1
O'Driscoll, B.R.2
Powell, G.3
-
68
-
-
0036142418
-
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: A randomized, double-blind, placebo-controlled trial
-
Dahlen SE, Malmstrom K, Nizankowska E, et al.: Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: A randomized, double-blind, placebo-controlled trial. Am J Respir Crit Care Med 2002, 165:9-14.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 9-14
-
-
Dahlen, S.E.1
Malmstrom, K.2
Nizankowska, E.3
-
69
-
-
19244370387
-
Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics
-
Dahlen B, Nizankowska E, Szczeklik A, et al.: Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. Am J Respir Crit Care Med 1998, 157:1187-1194.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1187-1194
-
-
Dahlen, B.1
Nizankowska, E.2
Szczeklik, A.3
-
70
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair P, Pizzichini MM, Kjarsgaard M, et al.: Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med 2009, 360:985-993.
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
-
71
-
-
38348998987
-
Clarithromycin targets neutrophilic airway inflammation in refractory asthma
-
Simpson JL, Powell H, Boyle MJ, et al.: Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med 2008, 177:148-155.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 148-155
-
-
Simpson, J.L.1
Powell, H.2
Boyle, M.J.3
-
72
-
-
34250370360
-
Bronchial mucosal inflammation and upregulation of CXC chemoattractants and receptors in severe exacerbations of asthma
-
Qiu Y, Zhu J, Bandi V, et al.: Bronchial mucosal inflammation and upregulation of CXC chemoattractants and receptors in severe exacerbations of asthma. Thorax 2007, 62:475-482.
-
(2007)
Thorax
, vol.62
, pp. 475-482
-
-
Qiu, Y.1
Zhu, J.2
Bandi, V.3
-
73
-
-
34247645201
-
A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma
-
Fardon T, Haggart K, Lee DK, Lipworth BJ: A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma. Respir Med 2007, 101:1218-1228.
-
(2007)
Respir Med
, vol.101
, pp. 1218-1228
-
-
Fardon, T.1
Haggart, K.2
Lee, D.K.3
Lipworth, B.J.4
-
74
-
-
37149034914
-
Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma
-
Pavord ID, Cox G, Thomson NC, et al.: Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med 2007, 176:1185-1191.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 1185-1191
-
-
Pavord, I.D.1
Cox, G.2
Thomson, N.C.3
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