Antibodies targeting linear determinants of the envelope protein protect mice against West Nile virus

Journal of Infectious Diseases

Volumn 196, Issue 12, 2007, Pages 1741-1748

  Ledizet, Michel ^a   Kar, Kalipada ^a   Foellmer, Harald G ^b   Bonafé, Nathalie ^a   Anthony, Karen G ^a   Gould, L Hannah ^b,d   Bushmich, Sandra L ^c   Fikrig, Erol ^b   Koski, Raymond A ^a  

^a L2 Diagnostics LLC   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

^d NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN; RECOMBINANT WEST NILE VIRUS ENVELOPE PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; GLYCOPROTEIN E, FLAVIVIRUS; PEPTIDE FRAGMENT; VIRUS ANTIBODY;

AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BINDING; FEMALE; IMMUNIZATION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; VIRUS INFECTION; VIRUS NEUTRALIZATION; WEST NILE FLAVIVIRUS; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY AFFINITY; C3H MOUSE; CERCOPITHECUS; DROSOPHILA; FLUORESCENT ANTIBODY TECHNIQUE; HORSE; IMMUNOLOGY; METHODOLOGY; MOLECULAR GENETICS; PASSIVE IMMUNIZATION; VERO CELL; VIROLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; ANTIBODY AFFINITY; CERCOPITHECUS AETHIOPS; DROSOPHILA; EPITOPES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HORSES; IMMUNIZATION, PASSIVE; IMMUNOGLOBULINS; MICE; MICE, INBRED C3H; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; VERO CELLS; VIRAL ENVELOPE PROTEINS; WEST NILE FEVER; WEST NILE VIRUS;

EID: 39149140001     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/523654     Document Type: Article

References (21)

1. Marfin AA, Gubler DJ. West Nile encephalitis: an emerging disease in the United States. Clin Infect Dis 2001; 33:1713-9.
2. Campbell GL, Marfin AA, Lanciotti RS, Gubler DJ. West Nile virus. Lancet Infect Dis 2002; 2:519-29.
3. Gould LH, Fikrig E. West Nile virus: a growing concern? J Clin Invest 2004; 113:1102-7.
4. Agrawal AG, Petersen LR. Human immunoglobulin as a treatment for West Nile virus infection. J Infect Dis 2003; 188:1-4.
5. Haley M, Retter AS, Fowler D, Gea-Banacloche J, O'Grady NP. The role for intravenous immunoglobulin in the treatment of West Nile virus encephalitis. Clin Infect Dis 2003; 37:e88-90.
6. Hamdan A, Green P, Mendelson E, Kramer MR, Pitlik S, Weinberger M. Possible benefit of intravenous immunoglobulin therapy in a lung transplant recipient with West Nile virus encephalitis. Transpl Infect Dis 2002; 4:160-2.
7. Shimoni Z, Niven MJ, Pitlick S, Bulvik S. Treatment of West Nile virus encephalitis with intravenous immunoglobulin. Emerg Infect Dis 2001; 7:759.
8. Goncalvez AP, Men R, Wernly C, Purcell RH, Lai CJ. Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses. J Virol 2004; 78:12910-8.
9. Gould LH, Sui J, Foellmer H, et al. Protective and therapeutic capacity of human single-chain Fv-Fc fusion proteins against West Nile virus. J Virol 2005; 79:14606-13.
10. Zhang W, Chipman PR, Corver J, et al. Visualization of membrane protein domains by cryo-electron microscopy of dengue virus. Nat Struct Biol 2003; 10:907-12.
11. Mukhopadhyay S, Kim BS, Chipman PR, Rossmann MG, Kuhn RJ. Structure of West Nile virus. Science 2003; 302:248.
12. Kanai R, Kar K, Anthony K, et al. Crystal structure of West Nile virus envelope glycoprotein reveals viral surface epitopes. J Virol 2006; 80:11000-8.
13. Nybakken GE, Nelson CA, Chen BR, Diamond MS, Fremont DH. Crystal structure of the West Nile virus envelope glycoprotein. J Virol 2006; 80:11467-74.
14. Sanchez MD, Pierson TC, McAllister D, et al. Characterization of neutralizing antibodies to West Nile virus. Virology 2005; 336:70-82.
15. Oliphant T, Engle M, Nybakken GE, et al. Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Nat Med 2005; 11:522-30.
16. Volk DE, Beasley DW, Kallick DA, Holbrook MR, Barrett AD, Gorenstein DG. Solution structure and antibody binding studies of the envelope protein domain III from the New York strain of West Nile virus. J Biol Chem 2004; 279:38755-61.
17. Engle MJ, Diamond MS. Antibody prophylaxis and therapy against West Nile virus infection in wild-type and immunodeficient mice. J Virol 2003; 77:12941-9.
18. Ledizet M, Kar K, Foellmer HG, et al. A recombinant envelope protein vaccine against West Nile virus. Vaccine 2005; 23:3915-24.
19. Wang T, Anderson JF, Magnarelli LA, Wong SJ, Koski RA, Fikrig E. Immunization of mice against West Nile virus with recombinant envelope protein. J Immunol 2001; 167:5273-7.
20. Oliphant T, Nybakken GE, Engle M, et al. Antibody recognition and neutralization determinants on domains I and II of west Nile Virus envelope protein. J Virol 2006; 80:12149-59.
21. Stiasny K, Kiermayr S, Holzmann H, Heinz FX. Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites. J Virol 2006; 80:9557-68.