-
1
-
-
33847024555
-
CAR and PXR: The xenobiotic-sensing receptors
-
Timsit, Y. E.; Negishi, M. CAR and PXR: the xenobiotic-sensing receptors. Steroids 2007, 72, 231-246.
-
(2007)
Steroids
, vol.72
, pp. 231-246
-
-
Timsit, Y.E.1
Negishi, M.2
-
2
-
-
0042236405
-
Identification of the nuclear receptor CAR: HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital
-
Yoshinari, K.; Kobayashi, K.; Moore, R.; Kawamoto, T.; Negishi, M. Identification of the nuclear receptor CAR: HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital. FEBS Lett. 2003, 548, 17-20.
-
(2003)
FEBS Lett
, vol.548
, pp. 17-20
-
-
Yoshinari, K.1
Kobayashi, K.2
Moore, R.3
Kawamoto, T.4
Negishi, M.5
-
3
-
-
0035038008
-
Phenobarbital response elements of cytochrome P450 genes and nuclear receptors
-
Sueyoshi, T.; Negishi, M. Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. Annu. Rev. Pharmacol. Toxicol. 2001, 41, 123-143.
-
(2001)
Annu. Rev. Pharmacol. Toxicol
, vol.41
, pp. 123-143
-
-
Sueyoshi, T.1
Negishi, M.2
-
4
-
-
0042315387
-
Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms
-
Lee, A. J.; Cai, M. X.; Thomas, P. E.; Conney, A. H.; Zhu, B. T. Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. Endocrinology 2003, 144, 3382-3398.
-
(2003)
Endocrinology
, vol.144
, pp. 3382-3398
-
-
Lee, A.J.1
Cai, M.X.2
Thomas, P.E.3
Conney, A.H.4
Zhu, B.T.5
-
5
-
-
14244270349
-
Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism
-
Qatanani, M.; Zhang, J.; Moore, D. D. Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism. Endocrinology 2005, 146, 995-1002.
-
(2005)
Endocrinology
, vol.146
, pp. 995-1002
-
-
Qatanani, M.1
Zhang, J.2
Moore, D.D.3
-
6
-
-
23044436687
-
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice
-
Wagner, M.; Halilbasic, E.; Marschall, H. U.; Zollner, G.; Fickert, P.; Langner, C.; Zatloukal, K.; Denk, H.; Trauner, M. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice. Hepatology 2005, 42, 420-430.
-
(2005)
Hepatology
, vol.42
, pp. 420-430
-
-
Wagner, M.1
Halilbasic, E.2
Marschall, H.U.3
Zollner, G.4
Fickert, P.5
Langner, C.6
Zatloukal, K.7
Denk, H.8
Trauner, M.9
-
7
-
-
5644295430
-
The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice
-
Yamamoto, Y.; Moore, R.; Goldsworthy, T. L.; Negishi, M.; Maronpot, R. R. The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice. Cancer Res. 2004, 64, 7197-7200.
-
(2004)
Cancer Res
, vol.64
, pp. 7197-7200
-
-
Yamamoto, Y.1
Moore, R.2
Goldsworthy, T.L.3
Negishi, M.4
Maronpot, R.R.5
-
8
-
-
0027992301
-
Global contamination by persistent organochlorines and their ecotoxicological impact on marine mammals
-
Tanabe, S.; Iwata, H.; Tatsukawa, R. Global contamination by persistent organochlorines and their ecotoxicological impact on marine mammals. Sci. Total Environ. 1994, 154, 163-177.
-
(1994)
Sci. Total Environ
, vol.154
, pp. 163-177
-
-
Tanabe, S.1
Iwata, H.2
Tatsukawa, R.3
-
9
-
-
5444251638
-
Polybrominated diphenyl ethers: Human tissue levels and toxicology
-
Gill, U.; Chu, I.; Ryan, J. J.; Feeley, M. Polybrominated diphenyl ethers: human tissue levels and toxicology. Rev. Environ. Contam. Toxicol. 2004, 183, 55-97.
-
(2004)
Rev. Environ. Contam. Toxicol
, vol.183
, pp. 55-97
-
-
Gill, U.1
Chu, I.2
Ryan, J.J.3
Feeley, M.4
-
10
-
-
1242297693
-
Polybrominated diphenyl ethers in the environment and in people: A meta-analysis of concentrations
-
Hites, R. A. Polybrominated diphenyl ethers in the environment and in people: A meta-analysis of concentrations. Environ. Sci. Technol. 2004, 38, 945-956.
-
(2004)
Environ. Sci. Technol
, vol.38
, pp. 945-956
-
-
Hites, R.A.1
-
11
-
-
0029562328
-
Structure-dependent induction of CYP2B by polychlorinated biphenyl congeners in female Sprague-Dawley rats
-
Connor, K.; Safe, S.; Jefcoate, C. R.; Larsen, M. Structure-dependent induction of CYP2B by polychlorinated biphenyl congeners in female Sprague-Dawley rats. Biochem. Pharmacol. 1995, 50, 1913-1920.
-
(1995)
Biochem. Pharmacol
, vol.50
, pp. 1913-1920
-
-
Connor, K.1
Safe, S.2
Jefcoate, C.R.3
Larsen, M.4
-
12
-
-
0036676483
-
Comparative responsiveness of hypothyroxinemia and hepatic enzyme induction in Long-Evans rats versus C57BL/6J mice exposed to TCDD-like and phenobarbital-like polychlorinated biphenyl congeners
-
Craft, E. S.; DeVito, M. J.; Crofton, K. M. Comparative responsiveness of hypothyroxinemia and hepatic enzyme induction in Long-Evans rats versus C57BL/6J mice exposed to TCDD-like and phenobarbital-like polychlorinated biphenyl congeners. Toxicol. Sci. 2002, 68, 372-380.
-
(2002)
Toxicol. Sci
, vol.68
, pp. 372-380
-
-
Craft, E.S.1
DeVito, M.J.2
Crofton, K.M.3
-
13
-
-
0028882317
-
Induction of cytochrome P-450 in the Norway rat Rattus norvegicus, following exposure to potential environmental contaminants
-
Nims, R. W.; Lubet, R. A. Induction of cytochrome P-450 in the Norway rat Rattus norvegicus, following exposure to potential environmental contaminants. J. Toxicol. Environ. Health 1995, 46, 271-292.
-
(1995)
J. Toxicol. Environ. Health
, vol.46
, pp. 271-292
-
-
Nims, R.W.1
Lubet, R.A.2
-
14
-
-
0042343720
-
The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor
-
Wyde, M. E.; Bartolucci, E.; Ueda, A.; Zhang, H.; Yan, B.; Negishi, M.; You, L. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor. Mol. Pharmacol. 2003, 64, 474-481.
-
(2003)
Mol. Pharmacol
, vol.64
, pp. 474-481
-
-
Wyde, M.E.1
Bartolucci, E.2
Ueda, A.3
Zhang, H.4
Yan, B.5
Negishi, M.6
You, L.7
-
15
-
-
27644470194
-
Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components
-
Sanders, J. M.; Burka, L. T.; Smith, C. S.; Black, W.; James, R.; Cunningham, M. L. Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components. Toxicol. Sci. 2005, 88, 127-133.
-
(2005)
Toxicol. Sci
, vol.88
, pp. 127-133
-
-
Sanders, J.M.1
Burka, L.T.2
Smith, C.S.3
Black, W.4
James, R.5
Cunningham, M.L.6
-
16
-
-
34347263448
-
Theflameretardants, polybrominated diphenyl ethers, are pregnane X receptor activators
-
Pacyniak, E. K.; Cheng, X.; Cunningham, M. L.; Crofton, K.; Klaassen, C. D.; Guo, G. L. Theflameretardants, polybrominated diphenyl ethers, are pregnane X receptor activators. Toxicol. Sci. 2007, 97, 94-102.
-
(2007)
Toxicol. Sci
, vol.97
, pp. 94-102
-
-
Pacyniak, E.K.1
Cheng, X.2
Cunningham, M.L.3
Crofton, K.4
Klaassen, C.D.5
Guo, G.L.6
-
17
-
-
29244462305
-
Subacute effects of the brominated flame retardants hexabromocyclododecane and tetrabromobisphenol A on hepatic cytochrome P450 levels in rats
-
Germer, S.; Piersma, A. H.; van der Ven, L.; Kamyschnikow, A.; Fery, Y.; Schmitz, H. J.; Schrenk, D. Subacute effects of the brominated flame retardants hexabromocyclododecane and tetrabromobisphenol A on hepatic cytochrome P450 levels in rats. Toxicology 2006, 218, 229-236.
-
(2006)
Toxicology
, vol.218
, pp. 229-236
-
-
Germer, S.1
Piersma, A.H.2
van der Ven, L.3
Kamyschnikow, A.4
Fery, Y.5
Schmitz, H.J.6
Schrenk, D.7
-
18
-
-
0028829552
-
Persistent organochlorine residues and their accumulation kinetics in Baikal seal (Phoca sibirica) from Lake Baikal, Russia
-
Nakata, H.; Tanabe, S.; Tatsukawa, R.; Amano, M.; Miyazaki, N.; Petrov, E. A. Persistent organochlorine residues and their accumulation kinetics in Baikal seal (Phoca sibirica) from Lake Baikal, Russia. Environ. Sci. Technol. 1995, 29, 2877-2885.
-
(1995)
Environ. Sci. Technol
, vol.29
, pp. 2877-2885
-
-
Nakata, H.1
Tanabe, S.2
Tatsukawa, R.3
Amano, M.4
Miyazaki, N.5
Petrov, E.A.6
-
19
-
-
0030619370
-
Bioaccumulation profiles of polychlorinated biphenyls including coplanar congeners and possible toxicological implications in Baikal seal (Phoca sibirica)
-
Nakata, H.; Tanabe, S.; Tatsukawa, R.; Amano, M.; Miyazaki, N.; Petrov, E. A. Bioaccumulation profiles of polychlorinated biphenyls including coplanar congeners and possible toxicological implications in Baikal seal (Phoca sibirica). Environ. Pollut. 1997, 95, 57-65.
-
(1997)
Environ. Pollut
, vol.95
, pp. 57-65
-
-
Nakata, H.1
Tanabe, S.2
Tatsukawa, R.3
Amano, M.4
Miyazaki, N.5
Petrov, E.A.6
-
20
-
-
3042787684
-
Toxicokinetics of PCDD, PCDF, and coplanarPCBcongeners in Baikal seals, Pusa sibirica: Age-related accumulation, maternal transfer, and hepatic sequestration
-
Iwata, H.; Watanabe, M.; Okajima, Y.; Tanabe, S.; Amano, M.; Miyazaki, N.; Petrov, E. A. Toxicokinetics of PCDD, PCDF, and coplanarPCBcongeners in Baikal seals, Pusa sibirica: age-related accumulation, maternal transfer, and hepatic sequestration. Environ. Sci. Technol. 2004, 38, 3505-3513.
-
(2004)
Environ. Sci. Technol
, vol.38
, pp. 3505-3513
-
-
Iwata, H.1
Watanabe, M.2
Okajima, Y.3
Tanabe, S.4
Amano, M.5
Miyazaki, N.6
Petrov, E.A.7
-
21
-
-
41649083246
-
Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 1. Residue level, tissue distribution, and temporal trend
-
Ishibashi, H.; Iwata, H.; Kim, E. Y.; Tao, L.; Kannan, K.; Amano, M.; Miyazaki, N.; Tanabe, S.; Batoev, V. B.; Petrov, E. A. Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 1. Residue level, tissue distribution, and temporal trend. Environ. Sci. Technol. 2008, 42, 2295-2301.
-
(2008)
Environ. Sci. Technol
, vol.42
, pp. 2295-2301
-
-
Ishibashi, H.1
Iwata, H.2
Kim, E.Y.3
Tao, L.4
Kannan, K.5
Amano, M.6
Miyazaki, N.7
Tanabe, S.8
Batoev, V.B.9
Petrov, E.A.10
-
22
-
-
23944472176
-
-
Kim, E. Y.; Iwata, H.; Suda, T.; Tanabe, S.; Amano, M.; Miyazaki, N.; Petrov, E. A. Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels. Comp. Biochem. Physiol. C 2005, 141, 281-291.
-
Kim, E. Y.; Iwata, H.; Suda, T.; Tanabe, S.; Amano, M.; Miyazaki, N.; Petrov, E. A. Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels. Comp. Biochem. Physiol. C 2005, 141, 281-291.
-
-
-
-
23
-
-
34447558488
-
Molecular characterization of cytochrome P450 1A1, 1A2, and 1B1, and effects of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners on their hepatic expression in Baikal seal (Pusa sibirica)
-
Hirakawa, S.; Iwata, H.; Takeshita, Y.; Kim, E. Y.; Sakamoto, T.; Okajima, Y.; Amano, M.; Miyazaki, N.; Petrov, E. A.; Tanabe, S. Molecular characterization of cytochrome P450 1A1, 1A2, and 1B1, and effects of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners on their hepatic expression in Baikal seal (Pusa sibirica). Toxicol. Sci. 2007, 97, 318-335.
-
(2007)
Toxicol. Sci
, vol.97
, pp. 318-335
-
-
Hirakawa, S.1
Iwata, H.2
Takeshita, Y.3
Kim, E.Y.4
Sakamoto, T.5
Okajima, Y.6
Amano, M.7
Miyazaki, N.8
Petrov, E.A.9
Tanabe, S.10
-
24
-
-
68849120527
-
Relative potencies for AHR-mediated toxicity of dioxins and related compounds in Baikal seal (Pusa sibirica) estimated by in vitro bioassay
-
Kim, E. Y.; Suda, T.; Iwata, H.; Petrov, E. A.; Tanabe, S. Relative potencies for AHR-mediated toxicity of dioxins and related compounds in Baikal seal (Pusa sibirica) estimated by in vitro bioassay. Organohalogen Compd. 2007, 69, 1850-1853.
-
(2007)
Organohalogen Compd
, vol.69
, pp. 1850-1853
-
-
Kim, E.Y.1
Suda, T.2
Iwata, H.3
Petrov, E.A.4
Tanabe, S.5
-
25
-
-
41649094043
-
Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 2. Molecular characterization, expression level, and transcriptional activation of peroxisome proliferator-activated receptor alpha
-
Ishibashi, H.; Iwata, H.; Kim, E. Y.; Tao, L.; Kannan, K.; Tanabe, S.; Batoev, V. B.; Petrov, E. A. Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 2. Molecular characterization, expression level, and transcriptional activation of peroxisome proliferator-activated receptor alpha. Environ. Sci. Technol. 2008, 42, 2302-2308.
-
(2008)
Environ. Sci. Technol
, vol.42
, pp. 2302-2308
-
-
Ishibashi, H.1
Iwata, H.2
Kim, E.Y.3
Tao, L.4
Kannan, K.5
Tanabe, S.6
Batoev, V.B.7
Petrov, E.A.8
-
26
-
-
0034685779
-
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
-
Moore, L. B.; Parks, D. J.; Jones, S. A.; Bledsoe, R. K.; Consler, T. G.; Stimmel, J. B.; Goodwin, B.; Liddle, C.; Blanchard, S. G.; Willson, T. M.; Collins, J. L.; Kliewer, S. A. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J. Biol. Chem. 2000, 275, 15122-15127.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 15122-15127
-
-
Moore, L.B.1
Parks, D.J.2
Jones, S.A.3
Bledsoe, R.K.4
Consler, T.G.5
Stimmel, J.B.6
Goodwin, B.7
Liddle, C.8
Blanchard, S.G.9
Willson, T.M.10
Collins, J.L.11
Kliewer, S.A.12
-
27
-
-
0036256351
-
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors
-
Moore, L. B.; Maglich, J. M.; McKee, D. D.; Wisely, B.; Willson, T. M.; Kliewer, S. A.; Lambert, M. H.; Moore, J. T. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors. Mol. Endocrinol. 2002, 16, 977-986.
-
(2002)
Mol. Endocrinol
, vol.16
, pp. 977-986
-
-
Moore, L.B.1
Maglich, J.M.2
McKee, D.D.3
Wisely, B.4
Willson, T.M.5
Kliewer, S.A.6
Lambert, M.H.7
Moore, J.T.8
-
28
-
-
0033999734
-
The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR
-
Tzameli, I.; Pissios, P.; Schuetz, E. G.; Moore, D. D. The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol. Cell. Biol. 2000, 20, 2951-2958.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 2951-2958
-
-
Tzameli, I.1
Pissios, P.2
Schuetz, E.G.3
Moore, D.D.4
-
29
-
-
33749588494
-
Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: Molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica)
-
Sakai, H.; Iwata, H.; Kim, E. Y.; Tsydenova, O.; Miyazaki, N.; Petrov, E. A.; Batoev, V. B.; Tanabe, S. Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica). Toxicol. Sci. 2006, 94, 57-70.
-
(2006)
Toxicol. Sci
, vol.94
, pp. 57-70
-
-
Sakai, H.1
Iwata, H.2
Kim, E.Y.3
Tsydenova, O.4
Miyazaki, N.5
Petrov, E.A.6
Batoev, V.B.7
Tanabe, S.8
-
30
-
-
0037931737
-
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
-
Maglich, J. M.; Parks, D. J.; Moore, L. B.; Collins, J. L.; Goodwin, B.; Billin, A. N.; Stoltz, C. A.; Kliewer, S. A.; Lambert, M. H.; Willson, T. M.; Moore, J. T. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J. Biol. Chem. 2003, 278, 17277-17283.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 17277-17283
-
-
Maglich, J.M.1
Parks, D.J.2
Moore, L.B.3
Collins, J.L.4
Goodwin, B.5
Billin, A.N.6
Stoltz, C.A.7
Kliewer, S.A.8
Lambert, M.H.9
Willson, T.M.10
Moore, J.T.11
-
31
-
-
0032497544
-
Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta
-
Forman, B. M.; Tzameli, I.; Choi, H. S.; Chen, J.; Simha, D.; Seol, W.; Evans, R. M.; Moore, D. D. Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature 1998, 395, 612-615.
-
(1998)
Nature
, vol.395
, pp. 612-615
-
-
Forman, B.M.1
Tzameli, I.2
Choi, H.S.3
Chen, J.4
Simha, D.5
Seol, W.6
Evans, R.M.7
Moore, D.D.8
-
32
-
-
3242668652
-
Polybrominated diphenyl ethers and organochlorines in archived northern fur seal samples from the Pacific coast of Japan, 1972-1998
-
Kajiwara, N.; Ueno, D.; Takahashi, A.; Baba, N.; Tanabe, S. Polybrominated diphenyl ethers and organochlorines in archived northern fur seal samples from the Pacific coast of Japan, 1972-1998. Environ. Sci. Technol. 2004, 38, 3804-3809.
-
(2004)
Environ. Sci. Technol
, vol.38
, pp. 3804-3809
-
-
Kajiwara, N.1
Ueno, D.2
Takahashi, A.3
Baba, N.4
Tanabe, S.5
-
33
-
-
33748620289
-
Temporal variation and biomagnification of organohalogen compounds in finless porpoises (Neophocaena phocaenoides) from the South China Sea
-
Ramu, K.; Kajiwara, N.; Lam, P. K.; Jefferson, T. A.; Zhou, K.; Tanabe, S. Temporal variation and biomagnification of organohalogen compounds in finless porpoises (Neophocaena phocaenoides) from the South China Sea. Environ. Pollut. 2006, 144, 516-523.
-
(2006)
Environ. Pollut
, vol.144
, pp. 516-523
-
-
Ramu, K.1
Kajiwara, N.2
Lam, P.K.3
Jefferson, T.A.4
Zhou, K.5
Tanabe, S.6
-
34
-
-
33646786799
-
Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor
-
Faucette, S. R.; Sueyoshi, T.; Smith, C. M.; Negishi, M.; Lecluyse, E. L.; Wang, H. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor. J. Pharmacol. Exp. Ther. 2006, 317, 1200-1209.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.317
, pp. 1200-1209
-
-
Faucette, S.R.1
Sueyoshi, T.2
Smith, C.M.3
Negishi, M.4
Lecluyse, E.L.5
Wang, H.6
-
35
-
-
33845881481
-
Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers
-
Faucette, S. R.; Zhang, T. C.; Moore, R.; Sueyoshi, T.; Omiecinski, C. J.; LeCluyse, E. L.; Negishi, M.; Wang, H. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. J. Pharmacol. Exp. Ther. 2007, 320, 72-80.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.320
, pp. 72-80
-
-
Faucette, S.R.1
Zhang, T.C.2
Moore, R.3
Sueyoshi, T.4
Omiecinski, C.J.5
LeCluyse, E.L.6
Negishi, M.7
Wang, H.8
-
36
-
-
0035933511
-
The human nuclear xenobiotic receptor PXR: Structural determinants of directed promiscuity
-
Watkins, R. E.; Wisely, G. B.; Moore, L. B.; Collins, J. L.; Lambert, M. H.; Williams, S. P.; Willson, T. M.; Kliewer, S. A.; Redinbo, M. R. The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity. Science 2001, 292, 2329-2333.
-
(2001)
Science
, vol.292
, pp. 2329-2333
-
-
Watkins, R.E.1
Wisely, G.B.2
Moore, L.B.3
Collins, J.L.4
Lambert, M.H.5
Williams, S.P.6
Willson, T.M.7
Kliewer, S.A.8
Redinbo, M.R.9
-
37
-
-
10944229118
-
Structure of the murine constitutive androstane receptor complexed to androstenol: A molecular basis for inverse agonism
-
Shan, L.; Vincent, J.; Brunzelle, J. S.; Dussault, I.; Lin, M.; Ianculescu, I.; Sherman, M. A.; Forman, B. M.; Fernandez, E. J. Structure of the murine constitutive androstane receptor complexed to androstenol: a molecular basis for inverse agonism. Mol. Cell 2004, 16, 907-917.
-
(2004)
Mol. Cell
, vol.16
, pp. 907-917
-
-
Shan, L.1
Vincent, J.2
Brunzelle, J.S.3
Dussault, I.4
Lin, M.5
Ianculescu, I.6
Sherman, M.A.7
Forman, B.M.8
Fernandez, E.J.9
-
38
-
-
10944250224
-
The nuclear xenobiotic receptor CAR: Structural determinants of constitutive activation and heterodimerization
-
Suino, K.; Peng, L.; Reynolds, R.; Li, Y.; Cha, J. Y.; Repa, J. J.; Kliewer, S. A.; Xu, H. E. The nuclear xenobiotic receptor CAR: structural determinants of constitutive activation and heterodimerization. Mol. Cell 2004, 16, 893-905.
-
(2004)
Mol. Cell
, vol.16
, pp. 893-905
-
-
Suino, K.1
Peng, L.2
Reynolds, R.3
Li, Y.4
Cha, J.Y.5
Repa, J.J.6
Kliewer, S.A.7
Xu, H.E.8
-
39
-
-
19944372389
-
A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer
-
Xu, R. X.; Lambert, M. H.; Wisely, B. B.; Warren, E. N.; Weinert, E. E.; Waitt, G. M.; Williams, J. D.; Collins, J. L.; Moore, L. B.; Willson, T. M.; Moore, J. T. A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer. Mol. Cell 2004, 16, 919-928.
-
(2004)
Mol. Cell
, vol.16
, pp. 919-928
-
-
Xu, R.X.1
Lambert, M.H.2
Wisely, B.B.3
Warren, E.N.4
Weinert, E.E.5
Waitt, G.M.6
Williams, J.D.7
Collins, J.L.8
Moore, L.B.9
Willson, T.M.10
Moore, J.T.11
-
40
-
-
0026564973
-
Cytochrome P450 in seals: Monooxygenase activities, immunochemical cross-reactions and response to phenobarbital treatment
-
Goksøyr, A.; Beyer, J.; Larsen, H. E.; Andersson, T.; Förlin, L. Cytochrome P450 in seals: monooxygenase activities, immunochemical cross-reactions and response to phenobarbital treatment. Mar. Environ. Res. 1992, 34, 113-116.
-
(1992)
Mar. Environ. Res
, vol.34
, pp. 113-116
-
-
Goksøyr, A.1
Beyer, J.2
Larsen, H.E.3
Andersson, T.4
Förlin, L.5
-
41
-
-
0031764238
-
Phase I and phase II enzyme activities in ringed seals (Phoca hispida): Characterization of hepatic cytochrome P450 by activity patterns, inhibition studies, mRNAa nalyses, and western blotting
-
Wolkers, J.; Witkamp, R. F.; Nijmeijer, S. M.; Burkow, I. C.; de Groene, E. M.; Lydersen, C.; Dahle, S.; Monshouwer, M. Phase I and phase II enzyme activities in ringed seals (Phoca hispida): characterization of hepatic cytochrome P450 by activity patterns, inhibition studies, mRNAa nalyses, and western blotting. Aquat. Toxicol. 1998, 44, 103-115.
-
(1998)
Aquat. Toxicol
, vol.44
, pp. 103-115
-
-
Wolkers, J.1
Witkamp, R.F.2
Nijmeijer, S.M.3
Burkow, I.C.4
de Groene, E.M.5
Lydersen, C.6
Dahle, S.7
Monshouwer, M.8
-
42
-
-
0032929559
-
Cytochrome P450-mediated enzyme activities and polychlorinated biphenyl accumulation in harp seal (Phoca groenlandica)
-
Wolkers, J.; Burkow, I. C.; Monshouwer, M.; Lydersen, C.; Dahle, S.; Witkamp, R. F. Cytochrome P450-mediated enzyme activities and polychlorinated biphenyl accumulation in harp seal (Phoca groenlandica). Mar. Environ. Res. 1999, 48, 59-72.
-
(1999)
Mar. Environ. Res
, vol.48
, pp. 59-72
-
-
Wolkers, J.1
Burkow, I.C.2
Monshouwer, M.3
Lydersen, C.4
Dahle, S.5
Witkamp, R.F.6
-
43
-
-
0035129022
-
Characterization of xenobiotic-metabolizing cytochrome P450 (CYP) forms in ringed and grey seals from the Baltic Sea and reference sites
-
Nyman, M.; Raunio, H.; Taavitsainen, P.; Pelkonen, O. Characterization of xenobiotic-metabolizing cytochrome P450 (CYP) forms in ringed and grey seals from the Baltic Sea and reference sites. Comp. Biochem. Physiol. C 2001, 128, 99-112.
-
(2001)
Comp. Biochem. Physiol. C
, vol.128
, pp. 99-112
-
-
Nyman, M.1
Raunio, H.2
Taavitsainen, P.3
Pelkonen, O.4
-
44
-
-
0031722206
-
Elevated levels of cytochrome P4501A (CYP1A) in ringed seals from the Baltic Sea
-
Mattson, M.; Raunio, H.; Pelkonen, O.; Helle, E. Elevated levels of cytochrome P4501A (CYP1A) in ringed seals from the Baltic Sea. Aquat. Toxicol. 1998, 43, 41-50.
-
(1998)
Aquat. Toxicol
, vol.43
, pp. 41-50
-
-
Mattson, M.1
Raunio, H.2
Pelkonen, O.3
Helle, E.4
-
45
-
-
0033800329
-
Expression and inducibility of members in the cytochrome P4501 (CYP1) family in ringed and grey seals from polluted and less polluted waters
-
Nyman, M.; Raunio, H.; Pelkonen, O. Expression and inducibility of members in the cytochrome P4501 (CYP1) family in ringed and grey seals from polluted and less polluted waters. Environ. Toxicol. Pharmacol. 2000, 8, 217-225.
-
(2000)
Environ. Toxicol. Pharmacol
, vol.8
, pp. 217-225
-
-
Nyman, M.1
Raunio, H.2
Pelkonen, O.3
-
46
-
-
0346665898
-
Hepatic microsomal cytochrome P450s and chlorinated hydrocarbons in largha and ribbon seals from Hokkaido, Japan: Differential response of seal species toAhreceptor agonist exposure
-
Chiba, I.; Sakakibara, A.; Iwata, T. H.; Ishizuka, M.; Tanabe, S.; Akahori, F.; Kazusaka, A.; Fujita, S. Hepatic microsomal cytochrome P450s and chlorinated hydrocarbons in largha and ribbon seals from Hokkaido, Japan: differential response of seal species toAhreceptor agonist exposure. Environ. Toxicol. Chem. 2002, 21, 794-806.
-
(2002)
Environ. Toxicol. Chem
, vol.21
, pp. 794-806
-
-
Chiba, I.1
Sakakibara, A.2
Iwata, T.H.3
Ishizuka, M.4
Tanabe, S.5
Akahori, F.6
Kazusaka, A.7
Fujita, S.8
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