Phase I and phase II enzyme activities in Ringed seals (Phoca hispida): Characterization of hepatic cytochrome P450 by activity patterns, inhibition studies, mRNA analyses, and western blotting

Aquatic Toxicology

Volumn 44, Issue 1-2, 1998, Pages 103-115

  Wolkers, J ^a   Witkamp, R F ^b   Nijmeijer, S M ^b   Burkow, I C ^c   De Groene, E M ^b   Lydersen, C ^d   Dahle, S ^a   Monshouwer, M ^b  

^a NORWEGIAN INSTITUTE FOR WATER RESEARCH   (Norway)

^b Div Pharmacol Pharm T   (Netherlands)

^c NORWEGIAN INSTITUTE FOR AIR RESEARCH   (Norway)

^d NORWEGIAN POLAR INSTITUTE   (Norway)

Author keywords

Catalytic activities; Cytochrome P450; Inhibition; Northern blot; Ringed seal; Western blot

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; MESSENGER RNA; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOBLOTTING; MAMMAL; MICROSOME; NONHUMAN; PRIORITY JOURNAL; SEAL; XENOBIOTIC METABOLISM;

PHOCA HISPIDA;

EID: 0031764238     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(98)00063-0     Document Type: Article

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