Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation

Transplant International

Volumn 21, Issue 5, 2008, Pages 483-494

  Liu, Yan ^a   Chen, Yan ^a   Liu, Fing Qin ^a   Lamb, Jonathan R ^b   Tam, Paul K H ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cardiac allografts; CD4+CD25+Foxp3+ T cells; DC SIGN; Rapamycin; Th1 Th2 cytokines; Triptolide

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; RAPAMYCIN; TRANSCRIPTION FACTOR FOXP3; TRIPTOLIDE;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC GRAFT REJECTION; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFICACY; GRAFT SURVIVAL; HEART GRAFT; HEART TRANSPLANTATION; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY CELL; MALE; MOUSE; NONHUMAN; PHENOTYPE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SPLEEN; SURVIVAL TIME; TH1 CELL; TH2 CELL; TREATMENT OUTCOME;

ANIMALS; CHEMOKINE CCL19; CHEMOKINE CCL21; DENDRITIC CELLS; DITERPENES; EPOXY COMPOUNDS; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-10; INTERLEUKIN-4; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PHENANTHRENES; SIROLIMUS; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTOR 4; TRANSPLANTATION, HOMOLOGOUS;

EID: 41749112206     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2007.00630.x     Document Type: Article

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