-
1
-
-
0043073213
-
Characterization of the neoplastic phenotype in the familial atypical multiple-mole melanoma-pancreatic carcinoma syndrome
-
Rulyak, S.J.; Brentnall, T.A.; Lynch, H.T.; Austin, M.A. Characterization of the neoplastic phenotype in the familial atypical multiple-mole melanoma-pancreatic carcinoma syndrome. Cancer, 2003, 98, 798-804.
-
(2003)
Cancer
, vol.98
, pp. 798-804
-
-
Rulyak, S.J.1
Brentnall, T.A.2
Lynch, H.T.3
Austin, M.A.4
-
2
-
-
0033836334
-
Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden)
-
Vasen, H.F.; Gruis, N.A.; Frants, R.R.; van Der Velden, P.A.; Hille, E.T.; Bergman, W. Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int. J. Cancer, 2000, 87, 809-811.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 809-811
-
-
Vasen, H.F.1
Gruis, N.A.2
Frants, R.R.3
van Der Velden, P.A.4
Hille, E.T.5
Bergman, W.6
-
3
-
-
0029664339
-
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
-
Zuo, L.; Weger, J.; Yang, Q.; Goldstein, A.M.; Tucker, M.A.; Walker, G.J.; Hayward, N.; Dracopoli, N.C. Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma. Nat. Genet., 1996, 12, 97-99.
-
(1996)
Nat. Genet
, vol.12
, pp. 97-99
-
-
Zuo, L.1
Weger, J.2
Yang, Q.3
Goldstein, A.M.4
Tucker, M.A.5
Walker, G.J.6
Hayward, N.7
Dracopoli, N.C.8
-
4
-
-
0038795172
-
Genetics of melanoma predisposition
-
Hayward, N.K. Genetics of melanoma predisposition. Oncogene, 2003, 22, 3053-3062.
-
(2003)
Oncogene
, vol.22
, pp. 3053-3062
-
-
Hayward, N.K.1
-
5
-
-
9144219528
-
Expression and localization of mutant p16 proteins in melanocytic lesions from familial melanoma patients
-
Ghiorzo, P.; Villaggio, B.; Sementa, A.R.; Hansson, J.; Platz, A.; Nicolo, G.; Spina, B.; Canepa, M.; Palmer, J.M.; Hayward, N.K.; Bianchi-Scarra, G. Expression and localization of mutant p16 proteins in melanocytic lesions from familial melanoma patients. Hum. Pathol., 2004, 35, 25-33.
-
(2004)
Hum. Pathol
, vol.35
, pp. 25-33
-
-
Ghiorzo, P.1
Villaggio, B.2
Sementa, A.R.3
Hansson, J.4
Platz, A.5
Nicolo, G.6
Spina, B.7
Canepa, M.8
Palmer, J.M.9
Hayward, N.K.10
Bianchi-Scarra, G.11
-
6
-
-
0141672223
-
Melanoma: Adjuvant therapy and other treatment options
-
Terando, A.; Sabel, M.S.; Sondak, V.K. Melanoma: adjuvant therapy and other treatment options. Curr. Treat. Options Oncol., 2003, 4, 187-199.
-
(2003)
Curr. Treat. Options Oncol
, vol.4
, pp. 187-199
-
-
Terando, A.1
Sabel, M.S.2
Sondak, V.K.3
-
7
-
-
0141888522
-
Pros and cons of adjuvant interferon in the treatment of melanoma
-
Sabel, M.S.; Sondak, V.K. Pros and cons of adjuvant interferon in the treatment of melanoma. Oncologist, 2003, 8, 451-458.
-
(2003)
Oncologist
, vol.8
, pp. 451-458
-
-
Sabel, M.S.1
Sondak, V.K.2
-
8
-
-
0028802721
-
Systemic treatments for advanced cutaneous melanoma
-
Anderson, C.M.; Buzaid, A.C.; Legha, S.S. Systemic treatments for advanced cutaneous melanoma. Oncology, 1995, 9, 1149-1158.
-
(1995)
Oncology
, vol.9
, pp. 1149-1158
-
-
Anderson, C.M.1
Buzaid, A.C.2
Legha, S.S.3
-
9
-
-
0034109653
-
-
Wagner, J.D.; Gordon, M.S.; Chuang, T.Y.; Coleman, J.J., 3rd. Current therapy of cutaneous melanoma. Plast. Reconstr. Surg., 2000, 105, 1774-1799, quiz 1800-1771.
-
Wagner, J.D.; Gordon, M.S.; Chuang, T.Y.; Coleman, J.J., 3rd. Current therapy of cutaneous melanoma. Plast. Reconstr. Surg., 2000, 105, 1774-1799, quiz 1800-1771.
-
-
-
-
10
-
-
0032858487
-
Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma
-
Chapman, P.B.; Einhorn, L.H.; Meyers, M.L.; Saxman, S.; Destro, A.N.; Panageas, K.S.; Begg, C.B.; Agarwala, S.S.; Schuchter, L.M.; Ernstoff, M.S.; Houghton, A.N.; Kirkwood, J.M. Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J. Clin. Oncol., 1999, 17, 2745-2751.
-
(1999)
J. Clin. Oncol
, vol.17
, pp. 2745-2751
-
-
Chapman, P.B.1
Einhorn, L.H.2
Meyers, M.L.3
Saxman, S.4
Destro, A.N.5
Panageas, K.S.6
Begg, C.B.7
Agarwala, S.S.8
Schuchter, L.M.9
Ernstoff, M.S.10
Houghton, A.N.11
Kirkwood, J.M.12
-
11
-
-
0033126406
-
Current therapy of cutaneous melanoma
-
Mays, S.R.; Nelson, B.R. Current therapy of cutaneous melanoma. Cutis, 1999, 63, 293-298.
-
(1999)
Cutis
, vol.63
, pp. 293-298
-
-
Mays, S.R.1
Nelson, B.R.2
-
12
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
-
Atkins, M.B.; Lotze, M.T.; Dutcher, J.P.; Fisher, R.I.; Weiss, G.; Margolin, K.; Abrams, J.; Sznol, M.; Parkinson, D.; Hawkins, M.; Paradise, C.; Kunkel, L.; Rosenberg, S.A. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J. Clin. Oncol., 1999, 17, 2105-2116.
-
(1999)
J. Clin. Oncol
, vol.17
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
Fisher, R.I.4
Weiss, G.5
Margolin, K.6
Abrams, J.7
Sznol, M.8
Parkinson, D.9
Hawkins, M.10
Paradise, C.11
Kunkel, L.12
Rosenberg, S.A.13
-
13
-
-
0033848628
-
High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update
-
Atkins, M.B.; Kunkel, L.; Sznol, M.; Rosenberg, S.A. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J., 2000, 6 (Suppl. 1), S11-14.
-
(2000)
Cancer J
, vol.6
, Issue.SUPPL. 1
-
-
Atkins, M.B.1
Kunkel, L.2
Sznol, M.3
Rosenberg, S.A.4
-
14
-
-
0028266553
-
Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2
-
Rosenberg, S.A.; Yang, J.C.; Topalian, S.L.; Schwartzentruber, D.J.; Weber, J.S.; Parkinson, D.R.; Seipp, C.A.; Einhorn, J.H.; White, D.E. Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA, 1994, 271, 907-913.
-
(1994)
JAMA
, vol.271
, pp. 907-913
-
-
Rosenberg, S.A.1
Yang, J.C.2
Topalian, S.L.3
Schwartzentruber, D.J.4
Weber, J.S.5
Parkinson, D.R.6
Seipp, C.A.7
Einhorn, J.H.8
White, D.E.9
-
15
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Curtin, J.A.; Fridlyand, J.; Kageshita, T.; Patel, H.N.; Busam, K.J.; Kutzner, H.; Cho, K.H.; Aiba, S.; Brocker, E.B.; LeBoit, P.E.; Pinkel, D.; Bastian, B.C. Distinct sets of genetic alterations in melanoma. N. Engl. J. Med., 2005, 353, 2135-2147.
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
Patel, H.N.4
Busam, K.J.5
Kutzner, H.6
Cho, K.H.7
Aiba, S.8
Brocker, E.B.9
LeBoit, P.E.10
Pinkel, D.11
Bastian, B.C.12
-
16
-
-
20444457621
-
BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs
-
Wong, C.W.; Fan, Y.S.; Chan, T.L.; Chan, A.S.; Ho, L.C.; Ma, T.K.; Yuen, S.T.; Leung, S.Y. BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs. J. Clin. Pathol., 2005, 58, 640-644.
-
(2005)
J. Clin. Pathol
, vol.58
, pp. 640-644
-
-
Wong, C.W.1
Fan, Y.S.2
Chan, T.L.3
Chan, A.S.4
Ho, L.C.5
Ma, T.K.6
Yuen, S.T.7
Leung, S.Y.8
-
17
-
-
33746263912
-
BRAF and NRAS mutations in melanoma and melanocytic nevi
-
Poynter, J.N.; Elder, J.T.; Fullen, D.R.; Nair, R.P.; Soengas, M.S.; Johnson, T.M.; Redman, B.; Thomas, N.E.; Gruber, S.B. BRAF and NRAS mutations in melanoma and melanocytic nevi. Melanoma Res., 2006, 16, 267-273.
-
(2006)
Melanoma Res
, vol.16
, pp. 267-273
-
-
Poynter, J.N.1
Elder, J.T.2
Fullen, D.R.3
Nair, R.P.4
Soengas, M.S.5
Johnson, T.M.6
Redman, B.7
Thomas, N.E.8
Gruber, S.B.9
-
18
-
-
33748053013
-
Cutaneous melanoma subtypes show different BRAF and NRAS mutation frequencies
-
Saldanha, G.; Potter, L.; Daforno, P.; Pringle, J.H. Cutaneous melanoma subtypes show different BRAF and NRAS mutation frequencies. Clin. Cancer Res., 2006, 12, 4499-4505.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 4499-4505
-
-
Saldanha, G.1
Potter, L.2
Daforno, P.3
Pringle, J.H.4
-
19
-
-
46349084183
-
Improving melanoma classification by integrating genetic and morphologic features
-
Viros, A.; Fridlyand, J.; Bauer, J.; Lasithiotakis, K.; Garbe, C.; Pinkel, D.; Bastian, B.C. Improving melanoma classification by integrating genetic and morphologic features. PLoS Med., 2008, 5, e120.
-
(2008)
PLoS Med
, vol.5
-
-
Viros, A.1
Fridlyand, J.2
Bauer, J.3
Lasithiotakis, K.4
Garbe, C.5
Pinkel, D.6
Bastian, B.C.7
-
20
-
-
10744222648
-
Mutations of the BRAF gene in benign and malignant melanocytic lesions
-
Yazdi, A.S.; Palmedo, G.; Flaig, M.J.; Puchta, U.; Reckwerth, A.; Rutten, A.; Mentzel, T.; Hugel, H.; Hantschke, M.; Schmid-Wendtner, M.H.; Kutzner, H.; Sander, C.A. Mutations of the BRAF gene in benign and malignant melanocytic lesions. J. Invest. Dermatol., 2003, 121, 1160-1162.
-
(2003)
J. Invest. Dermatol
, vol.121
, pp. 1160-1162
-
-
Yazdi, A.S.1
Palmedo, G.2
Flaig, M.J.3
Puchta, U.4
Reckwerth, A.5
Rutten, A.6
Mentzel, T.7
Hugel, H.8
Hantschke, M.9
Schmid-Wendtner, M.H.10
Kutzner, H.11
Sander, C.A.12
-
21
-
-
0037228055
-
High frequency of BRAF mutations in nevi
-
Pollock, P.M.; Harper, U.L.; Hansen, K.S.; Yudt, L.M.; Stark, M.; Robbins, C.M.; Moses, T.Y.; Hostetter, G.; Wagner, U.; Kakareka, J.; Salem, G.; Pohida, T.; Heenan, P.; Duray, P.; Kallioniemi, O.; Hayward, N.K.; Trent, J.M.; Meltzer, P.S. High frequency of BRAF mutations in nevi. Nat. Genet., 2003, 33, 19-20.
-
(2003)
Nat. Genet
, vol.33
, pp. 19-20
-
-
Pollock, P.M.1
Harper, U.L.2
Hansen, K.S.3
Yudt, L.M.4
Stark, M.5
Robbins, C.M.6
Moses, T.Y.7
Hostetter, G.8
Wagner, U.9
Kakareka, J.10
Salem, G.11
Pohida, T.12
Heenan, P.13
Duray, P.14
Kallioniemi, O.15
Hayward, N.K.16
Trent, J.M.17
Meltzer, P.S.18
-
22
-
-
33748325725
-
Rapid screening of 4000 individuals for germ-line variations in the BRAF gene
-
James, M.R.; Dumeni, T.; Stark, M.S.; Duffy, D.L.; Montgomery, G.W.; Martin, N.G.; Hayward, N.K. Rapid screening of 4000 individuals for germ-line variations in the BRAF gene. Clin. Chem., 2006, 52, 1675-1678.
-
(2006)
Clin. Chem
, vol.52
, pp. 1675-1678
-
-
James, M.R.1
Dumeni, T.2
Stark, M.S.3
Duffy, D.L.4
Montgomery, G.W.5
Martin, N.G.6
Hayward, N.K.7
-
23
-
-
0035670803
-
Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma
-
Demunter, A.; Stas, M.; Degreef, H.; De Wolf-Peeters, C.; van den Oord, J.J. Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma. J. Invest. Dermatol., 2001, 117, 1483-1489.
-
(2001)
J. Invest. Dermatol
, vol.117
, pp. 1483-1489
-
-
Demunter, A.1
Stas, M.2
Degreef, H.3
De Wolf-Peeters, C.4
van den Oord, J.J.5
-
24
-
-
49649118852
-
Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma
-
Montagut, C.; Sharma, S.V.; Shioda, T.; McDermott, U.; Ulman, M.; Ulkus, L.E.; Dias-Santagata, D.; Stubbs, H.; Lee, D.Y.; Singh, A.; Drew, L.; Haber, D.A.; Settleman, J. Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma. Cancer Res., 2008, 68, 4853-4861.
-
(2008)
Cancer Res
, vol.68
, pp. 4853-4861
-
-
Montagut, C.1
Sharma, S.V.2
Shioda, T.3
McDermott, U.4
Ulman, M.5
Ulkus, L.E.6
Dias-Santagata, D.7
Stubbs, H.8
Lee, D.Y.9
Singh, A.10
Drew, L.11
Haber, D.A.12
Settleman, J.13
-
25
-
-
33845726945
-
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations
-
Bauer, J.; Curtin, J.A.; Pinkel, D.; Bastian, B.C. Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. J. Invest. Dermatol., 2007, 127, 179-182.
-
(2007)
J. Invest. Dermatol
, vol.127
, pp. 179-182
-
-
Bauer, J.1
Curtin, J.A.2
Pinkel, D.3
Bastian, B.C.4
-
26
-
-
33749021085
-
Somatic activation of KIT in distinct subtypes of melanoma
-
Curtin, J.A.; Busam, K.; Pinkel, D.; Bastian, B.C. Somatic activation of KIT in distinct subtypes of melanoma. J. Clin. Oncol., 2006, 24, 4340-4346.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 4340-4346
-
-
Curtin, J.A.1
Busam, K.2
Pinkel, D.3
Bastian, B.C.4
-
27
-
-
58149260596
-
KIT gene mutations and copy number in melanoma subtypes
-
Beadling, C.; Jacobson-Dunlop, E.; Hodi, F.S.; Le, C.; Warrick, A.; Patterson, J.; Town, A.; Harlow, A.; Cruz, F., 3rd.; Azar, S.; Rubin, B.P.; Muller, S.; West, R.; Heinrich, M.C.; Corless, C.L. KIT gene mutations and copy number in melanoma subtypes. Clin. Cancer Res., 2008, 14, 6821-6828.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 6821-6828
-
-
Beadling, C.1
Jacobson-Dunlop, E.2
Hodi, F.S.3
Le, C.4
Warrick, A.5
Patterson, J.6
Town, A.7
Harlow, A.8
Cruz 3rd, F.9
Azar, S.10
Rubin, B.P.11
Muller, S.12
West, R.13
Heinrich, M.C.14
Corless, C.L.15
-
28
-
-
59449085455
-
Imatinib targeting of KIT-mutant oncoprotein in melanoma
-
Jiang, X.; Zhou, J.; Yuen, N.K.; Corless, C.L.; Heinrich, M.C.; Fletcher, J.A.; Demetri, G.D.; Widlund, H.R.; Fisher, D.E.; Hodi, F.S. Imatinib targeting of KIT-mutant oncoprotein in melanoma. Clin. Cancer Res., 2008, 14, 7726-7732.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 7726-7732
-
-
Jiang, X.1
Zhou, J.2
Yuen, N.K.3
Corless, C.L.4
Heinrich, M.C.5
Fletcher, J.A.6
Demetri, G.D.7
Widlund, H.R.8
Fisher, D.E.9
Hodi, F.S.10
-
29
-
-
47249099056
-
Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation
-
Lutzky, J.; Bauer, J.; Bastian, B.C. Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation. Pigment Cell Melanoma Res., 2008, 21, 492-493.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, pp. 492-493
-
-
Lutzky, J.1
Bauer, J.2
Bastian, B.C.3
-
30
-
-
61549103137
-
Expression of sorafenib targets in melanoma patients treated with Carboplatin, Paclitaxel and sorafenib
-
Jilaveanu, L.; Zito, C.; Lee, S.J.; Nathanson, K.L.; Camp, R.L.; Rimm, D.L.; Flaherty, K.T.; Kluger, H.M. Expression of sorafenib targets in melanoma patients treated with Carboplatin, Paclitaxel and sorafenib. Clin. Cancer Res., 2009, 15, 1076-1085.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 1076-1085
-
-
Jilaveanu, L.1
Zito, C.2
Lee, S.J.3
Nathanson, K.L.4
Camp, R.L.5
Rimm, D.L.6
Flaherty, K.T.7
Kluger, H.M.8
-
31
-
-
57049109807
-
Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib
-
Quintas-Cardama, A.; Lazar, A.J.; Woodman, S.E.; Kim, K.; Ross, M.; Hwu, P. Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib. Nat. Clin. Pract. Oncol., 2008, 5, 737-740.
-
(2008)
Nat. Clin. Pract. Oncol
, vol.5
, pp. 737-740
-
-
Quintas-Cardama, A.1
Lazar, A.J.2
Woodman, S.E.3
Kim, K.4
Ross, M.5
Hwu, P.6
-
32
-
-
34548692277
-
EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis
-
Rakosy, Z.; Vizkeleti, L.; Ecsedi, S.; Voko, Z.; Begany, A.; Barok, M.; Krekk, Z.; Gallai, M.; Szentirmay, Z.; Adany, R.; Balazs, M. EGFR gene copy number alterations in primary cutaneous malignant melanomas are associated with poor prognosis. Int. J. Cancer, 2007, 121, 1729-1737.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 1729-1737
-
-
Rakosy, Z.1
Vizkeleti, L.2
Ecsedi, S.3
Voko, Z.4
Begany, A.5
Barok, M.6
Krekk, Z.7
Gallai, M.8
Szentirmay, Z.9
Adany, R.10
Balazs, M.11
-
33
-
-
0141958794
-
Analysis of protein tyrosine kinase expression in melanocytic lesions by tissue array
-
Shen, S.S.; Zhang, P.S.; Eton, O.; Prieto, V.G. Analysis of protein tyrosine kinase expression in melanocytic lesions by tissue array. J. Cutan. Pathol., 2003, 30, 539-547.
-
(2003)
J. Cutan. Pathol
, vol.30
, pp. 539-547
-
-
Shen, S.S.1
Zhang, P.S.2
Eton, O.3
Prieto, V.G.4
-
34
-
-
0142151099
-
Classifying melanocytic tumors based on DNA copy number changes
-
Bastian, B.C.; Olshen, A.B.; LeBoit, P.E.; Pinkel, D. Classifying melanocytic tumors based on DNA copy number changes. Am. J. Pathol., 2003, 163, 1765-1770.
-
(2003)
Am. J. Pathol
, vol.163
, pp. 1765-1770
-
-
Bastian, B.C.1
Olshen, A.B.2
LeBoit, P.E.3
Pinkel, D.4
-
35
-
-
29244460131
-
Genomic analysis of melanocytic neoplasia
-
Bauer, J.; Bastian, B. Genomic analysis of melanocytic neoplasia. Adv. Dermatol., 2005, 21, 81-99.
-
(2005)
Adv. Dermatol
, vol.21
, pp. 81-99
-
-
Bauer, J.1
Bastian, B.2
-
36
-
-
68749104627
-
-
Riker, A.I.; Enkemann, S.A.; Fodstad, O.; Liu, S.; Ren, S.; Morris, C.; Xi, Y.; Howell, P.; Metge, B.; Samant, R.S.; Shevde, L.A.; Li, W.; Eschrich, S.; Daud, A.; Ju, J.; Matta, J. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. BMC Med. Genomics, 2008, 1, 13.
-
Riker, A.I.; Enkemann, S.A.; Fodstad, O.; Liu, S.; Ren, S.; Morris, C.; Xi, Y.; Howell, P.; Metge, B.; Samant, R.S.; Shevde, L.A.; Li, W.; Eschrich, S.; Daud, A.; Ju, J.; Matta, J. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. BMC Med. Genomics, 2008, 1, 13.
-
-
-
-
37
-
-
58749107496
-
Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma
-
Gartside, M.G.; Chen, H.; Ibrahimi, O.A.; Byron, S.A.; Curtis, A.V.; Wellens, C.L.; Bengston, A.; Yudt, L.M.; Eliseenkova, A.V.; Ma, J.; Curtin, J.A.; Hyder, P.; Harper, U.L.; Riedesel, E.; Mann, G.J.; Trent, J.M.; Bastian, B.C.; Meltzer, P.S.; Mohammadi, M.; Pollock, P.M. Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma. Mol. Cancer Res., 2009, 7, 41-54.
-
(2009)
Mol. Cancer Res
, vol.7
, pp. 41-54
-
-
Gartside, M.G.1
Chen, H.2
Ibrahimi, O.A.3
Byron, S.A.4
Curtis, A.V.5
Wellens, C.L.6
Bengston, A.7
Yudt, L.M.8
Eliseenkova, A.V.9
Ma, J.10
Curtin, J.A.11
Hyder, P.12
Harper, U.L.13
Riedesel, E.14
Mann, G.J.15
Trent, J.M.16
Bastian, B.C.17
Meltzer, P.S.18
Mohammadi, M.19
Pollock, P.M.20
more..
-
38
-
-
4043055279
-
BRAF alterations are associated with complex mutational profiles in malignant melanoma
-
Daniotti, M.; Oggionni, M.; Ranzani, T.; Vallacchi, V.; Campi, V.; Di Stasi, D.; Torre, G.D.; Perrone, F.; Luoni, C.; Suardi, S.; Frattini, M.; Pilotti, S.; Anichini, A.; Tragni, G.; Parmiani, G.; Pierotti, M.A.; Rodolfo, M. BRAF alterations are associated with complex mutational profiles in malignant melanoma. Oncogene, 2004.
-
(2004)
Oncogene
-
-
Daniotti, M.1
Oggionni, M.2
Ranzani, T.3
Vallacchi, V.4
Campi, V.5
Di Stasi, D.6
Torre, G.D.7
Perrone, F.8
Luoni, C.9
Suardi, S.10
Frattini, M.11
Pilotti, S.12
Anichini, A.13
Tragni, G.14
Parmiani, G.15
Pierotti, M.A.16
Rodolfo, M.17
-
39
-
-
33644822256
-
High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma
-
Abdel-Rahman, M.H.; Yang, Y.; Zhou, X.P.; Craig, E.L.; Davidorf, F.H.; Eng, C. High frequency of submicroscopic hemizygous deletion is a major mechanism of loss of expression of PTEN in uveal melanoma. J. Clin. Oncol., 2006, 24, 288-295.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 288-295
-
-
Abdel-Rahman, M.H.1
Yang, Y.2
Zhou, X.P.3
Craig, E.L.4
Davidorf, F.H.5
Eng, C.6
-
40
-
-
25844522712
-
Expression of activated Akt and PTEN in malignant melanomas: Relationship with clinical outcome
-
Slipicevic, A.; Holm, R.; Nguyen, M.T.; Bohler, P.J.; Davidson, B.; Florenes, V.A. Expression of activated Akt and PTEN in malignant melanomas: relationship with clinical outcome. Am. J. Clin. Pathol., 2005, 124, 528-536.
-
(2005)
Am. J. Clin. Pathol
, vol.124
, pp. 528-536
-
-
Slipicevic, A.1
Holm, R.2
Nguyen, M.T.3
Bohler, P.J.4
Davidson, B.5
Florenes, V.A.6
-
41
-
-
33746114249
-
Epigenetic silencing of the PTEN gene in melanoma
-
Mirmohammadsadegh, A.; Marini, A.; Nambiar, S.; Hassan, M.; Tannapfel, A.; Ruzicka, T.; Hengge, U.R. Epigenetic silencing of the PTEN gene in melanoma. Cancer Res., 2006, 66, 6546-6552.
-
(2006)
Cancer Res
, vol.66
, pp. 6546-6552
-
-
Mirmohammadsadegh, A.1
Marini, A.2
Nambiar, S.3
Hassan, M.4
Tannapfel, A.5
Ruzicka, T.6
Hengge, U.R.7
-
42
-
-
33644774541
-
Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma
-
Goel, V.K.; Lazar, A.J.; Warneke, C.L.; Redston, M.S.; Haluska, F.G. Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma. J. Invest. Dermatol., 2006, 126, 154-160.
-
(2006)
J. Invest. Dermatol
, vol.126
, pp. 154-160
-
-
Goel, V.K.1
Lazar, A.J.2
Warneke, C.L.3
Redston, M.S.4
Haluska, F.G.5
-
43
-
-
0038456399
-
PTEN signaling pathways in melanoma
-
Wu, H.; Goel, V.; Haluska, F.G. PTEN signaling pathways in melanoma. Oncogene, 2003, 22, 3113-3122.
-
(2003)
Oncogene
, vol.22
, pp. 3113-3122
-
-
Wu, H.1
Goel, V.2
Haluska, F.G.3
-
44
-
-
53849132331
-
A novel AKT3 mutation in melanoma tumours and cell lines
-
Davies, M.A.; Stemke-Hale, K.; Tellez, C.; Calderone, T.L.; Deng, W.; Prieto, V.G.; Lazar, A.J.; Gershenwald, J.E.; Mills, G.B. A novel AKT3 mutation in melanoma tumours and cell lines. Br. J. Cancer, 2008, 99, 1265-1268.
-
(2008)
Br. J. Cancer
, vol.99
, pp. 1265-1268
-
-
Davies, M.A.1
Stemke-Hale, K.2
Tellez, C.3
Calderone, T.L.4
Deng, W.5
Prieto, V.G.6
Lazar, A.J.7
Gershenwald, J.E.8
Mills, G.B.9
-
45
-
-
4944249733
-
Deregulated Akt3 activity promotes development of malignant melanoma
-
Stahl, J.M.; Sharma, A.; Cheung, M.; Zimmerman, M.; Cheng, J.Q.; Bosenberg, M.W.; Kester, M.; Sandirasegarane, L.; Robertson, G.P. Deregulated Akt3 activity promotes development of malignant melanoma. Cancer Res., 2004, 64, 7002-7010.
-
(2004)
Cancer Res
, vol.64
, pp. 7002-7010
-
-
Stahl, J.M.1
Sharma, A.2
Cheung, M.3
Zimmerman, M.4
Cheng, J.Q.5
Bosenberg, M.W.6
Kester, M.7
Sandirasegarane, L.8
Robertson, G.P.9
-
46
-
-
33847417986
-
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma
-
Govindarajan, B.; Sligh, J.E.; Vincent, B.J.; Li, M.; Canter, J.A.; Nickoloff, B.J.; Rodenburg, R.J.; Smeitink, J.A.; Oberley, L.; Zhang, Y.; Slingerland, J.; Arnold, R.S.; Lambeth, J.D.; Cohen, C.; Hilenski, L.; Griendling, K.; Martinez-Diez, M.; Cuezva, J.M.; Arbiser, J.L. Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. J. Clin. Invest., 2007, 117, 719-729.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 719-729
-
-
Govindarajan, B.1
Sligh, J.E.2
Vincent, B.J.3
Li, M.4
Canter, J.A.5
Nickoloff, B.J.6
Rodenburg, R.J.7
Smeitink, J.A.8
Oberley, L.9
Zhang, Y.10
Slingerland, J.11
Arnold, R.S.12
Lambeth, J.D.13
Cohen, C.14
Hilenski, L.15
Griendling, K.16
Martinez-Diez, M.17
Cuezva, J.M.18
Arbiser, J.L.19
-
47
-
-
42449147592
-
Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma
-
Akslen, L.A.; Puntervoll, H.; Bachmann, I.M.; Straume, O.; Vuhahula, E.; Kumar, R.; Molven, A. Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma. Melanoma Res., 2008, 18, 29-35.
-
(2008)
Melanoma Res
, vol.18
, pp. 29-35
-
-
Akslen, L.A.1
Puntervoll, H.2
Bachmann, I.M.3
Straume, O.4
Vuhahula, E.5
Kumar, R.6
Molven, A.7
-
48
-
-
51749086380
-
Germline MC1R variants and BRAF mutant melanoma
-
Hacker, E.; Hayward, N.K. Germline MC1R variants and BRAF mutant melanoma. J. Invest. Dermatol., 2008, 128, 2354-2356.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 2354-2356
-
-
Hacker, E.1
Hayward, N.K.2
-
49
-
-
0037134702
-
Geographical variation in the penetrance of CDKN2A mutations for melanoma
-
Bishop, D.T.; Demenais, F.; Goldstein, A.M.; Bergman, W.; Bishop, J.N.; Bressac-de Paillerets, B.; Chompret, A.; Ghiorzo, P.; Gruis, N.; Hansson, J.; Harland, M.; Hayward, N.; Holland, E.A.; Mann, G.J.; Mantelli, M.; Nancarrow, D.; Platz, A.; Tucker, M.A. Geographical variation in the penetrance of CDKN2A mutations for melanoma. J. Natl. Cancer Inst., 2002, 94, 894-903.
-
(2002)
J. Natl. Cancer Inst
, vol.94
, pp. 894-903
-
-
Bishop, D.T.1
Demenais, F.2
Goldstein, A.M.3
Bergman, W.4
Bishop, J.N.5
Bressac-de Paillerets, B.6
Chompret, A.7
Ghiorzo, P.8
Gruis, N.9
Hansson, J.10
Harland, M.11
Hayward, N.12
Holland, E.A.13
Mann, G.J.14
Mantelli, M.15
Nancarrow, D.16
Platz, A.17
Tucker, M.A.18
-
50
-
-
45549095449
-
-
Brown, K.M.; Macgregor, S.; Montgomery, G.W.; Craig, D.W.; Zhao, Z.Z.; Iyadurai, K.; Henders, A.K.; Homer, N.; Campbell, M.J.; Stark, M.; Thomas, S.; Schmid, H.; Holland, E.A.; Gillanders, E.M.; Duffy, D.L.; Maskiell, J.A.; Jetann, J.; Ferguson, M.; Stephan, D.A.; Cust, A.E.; Whiteman, D.; Green, A.; Olsson, H.; Puig, S.; Ghiorzo, P.; Hansson, J.; Demenais, F.; Goldstein, A.M.; Gruis, N.A.; Elder, D.E.; Bishop, J.N.; Kefford, R.F.; Giles, G.G.; Armstrong, B.K.; Aitken, J.F.; Hopper, J.L.; Martin, N.G.; Trent, J.M.; Mann, G.J.; Hayward, N.K. Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat. Genet., 2008, 40, 838-840.
-
Brown, K.M.; Macgregor, S.; Montgomery, G.W.; Craig, D.W.; Zhao, Z.Z.; Iyadurai, K.; Henders, A.K.; Homer, N.; Campbell, M.J.; Stark, M.; Thomas, S.; Schmid, H.; Holland, E.A.; Gillanders, E.M.; Duffy, D.L.; Maskiell, J.A.; Jetann, J.; Ferguson, M.; Stephan, D.A.; Cust, A.E.; Whiteman, D.; Green, A.; Olsson, H.; Puig, S.; Ghiorzo, P.; Hansson, J.; Demenais, F.; Goldstein, A.M.; Gruis, N.A.; Elder, D.E.; Bishop, J.N.; Kefford, R.F.; Giles, G.G.; Armstrong, B.K.; Aitken, J.F.; Hopper, J.L.; Martin, N.G.; Trent, J.M.; Mann, G.J.; Hayward, N.K. Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat. Genet., 2008, 40, 838-840.
-
-
-
-
51
-
-
51049095131
-
A phase I trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel
-
Flaherty, K.T.; Schiller, J.; Schuchter, L.M.; Liu, G.; Tuveson, D.A.; Redlinger, M.; Lathia, C.; Xia, C.; Petrenciuc, O.; Hingorani, S.R.; Jacobetz, M.A.; Van Belle, P.A.; Elder, D.; Brose, M.S.; Weber, B.L.; Albertini, M.R.; O'Dwyer, P.J. A phase I trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel. Clin. Cancer Res., 2008, 14, 4836-4842.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 4836-4842
-
-
Flaherty, K.T.1
Schiller, J.2
Schuchter, L.M.3
Liu, G.4
Tuveson, D.A.5
Redlinger, M.6
Lathia, C.7
Xia, C.8
Petrenciuc, O.9
Hingorani, S.R.10
Jacobetz, M.A.11
Van Belle, P.A.12
Elder, D.13
Brose, M.S.14
Weber, B.L.15
Albertini, M.R.16
O'Dwyer, P.J.17
-
52
-
-
50249141632
-
Phase II trial of imatinib mesylate in patients with metastatic melanoma
-
Kim, K.B.; Eton, O.; Davis, D.W.; Frazier, M.L.; McConkey, D.J.; Diwan, A.H.; Papadopoulos, N.E.; Bedikian, A.Y.; Camacho, L.H.; Ross, M.I.; Cormier, J.N.; Gershenwald, J.E.; Lee, J.E.; Mansfield, P.F.; Billings, L.A.; Ng, C.S.; Charnsangavej, C.; Bar-Eli, M.; Johnson, M.M.; Murgo, A.J.; Prieto, V.G. Phase II trial of imatinib mesylate in patients with metastatic melanoma. Br. J. Cancer, 2008, 99, 734-740.
-
(2008)
Br. J. Cancer
, vol.99
, pp. 734-740
-
-
Kim, K.B.1
Eton, O.2
Davis, D.W.3
Frazier, M.L.4
McConkey, D.J.5
Diwan, A.H.6
Papadopoulos, N.E.7
Bedikian, A.Y.8
Camacho, L.H.9
Ross, M.I.10
Cormier, J.N.11
Gershenwald, J.E.12
Lee, J.E.13
Mansfield, P.F.14
Billings, L.A.15
Ng, C.S.16
Charnsangavej, C.17
Bar-Eli, M.18
Johnson, M.M.19
Murgo, A.J.20
Prieto, V.G.21
more..
-
53
-
-
0035392955
-
Promoter hypermethylation: A common cause of reduced p16(INK4a) expression in uveal melanoma
-
van der Velden, P.A.; Metzelaar-Blok, J.A.; Bergman, W.; Monique, H.; Hurks, H.; Frants, R.R.; Gruis, N.A.; Jager, M.J. Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma. Cancer Res., 2001, 61, 5303-5306.
-
(2001)
Cancer Res
, vol.61
, pp. 5303-5306
-
-
van der Velden, P.A.1
Metzelaar-Blok, J.A.2
Bergman, W.3
Monique, H.4
Hurks, H.5
Frants, R.R.6
Gruis, N.A.7
Jager, M.J.8
-
54
-
-
3142710392
-
Genetic and epigenetic alterations of the APC gene in malignant melanoma
-
Worm, J.; Christensen, C.; Gronbaek, K.; Tulchinsky, E.; Guldberg, P. Genetic and epigenetic alterations of the APC gene in malignant melanoma. Oncogene, 2004, 23, 5215-5226.
-
(2004)
Oncogene
, vol.23
, pp. 5215-5226
-
-
Worm, J.1
Christensen, C.2
Gronbaek, K.3
Tulchinsky, E.4
Guldberg, P.5
-
55
-
-
0037380925
-
Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma
-
Spugnardi, M.; Tommasi, S.; Dammann, R.; Pfeifer, G.P.; Hoon, D.S. Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma. Cancer Res., 2003, 63, 1639-1643.
-
(2003)
Cancer Res
, vol.63
, pp. 1639-1643
-
-
Spugnardi, M.1
Tommasi, S.2
Dammann, R.3
Pfeifer, G.P.4
Hoon, D.S.5
-
56
-
-
34447130813
-
Frequent intra-tumoural heterogeneity of promoter hypermethylation in malignant melanoma
-
Rastetter, M.; Schagdarsurengin, U.; Lahtz, C.; Fiedler, E.; Marsch, W.; Dammann, R.; Helmbold, P. Frequent intra-tumoural heterogeneity of promoter hypermethylation in malignant melanoma. Histol. Histopathol., 2007, 22, 1005-1015.
-
(2007)
Histol. Histopathol
, vol.22
, pp. 1005-1015
-
-
Rastetter, M.1
Schagdarsurengin, U.2
Lahtz, C.3
Fiedler, E.4
Marsch, W.5
Dammann, R.6
Helmbold, P.7
-
57
-
-
31544464704
-
Targeted modulation of MGMT: Clinical implications
-
Liu, L.; Gerson, S.L. Targeted modulation of MGMT: clinical implications. Clin. Cancer Res., 2006, 12, 328-331.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 328-331
-
-
Liu, L.1
Gerson, S.L.2
-
58
-
-
1542574206
-
Progression in cutaneous malignant melanoma is associated with distinct expression profiles: A tissue microarray-based study
-
Alonso, S.R.; Ortiz, P.; Pollan, M.; Perez-Gomez, B.; Sanchez, L.; Acuna, M.J.; Pajares, R.; Martinez-Tello, F.J.; Hortelano, C.M.; Piris, M.A.; Rodriguez-Peralto, J.L. Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study. Am. J. Pathol., 2004, 164, 193-203.
-
(2004)
Am. J. Pathol
, vol.164
, pp. 193-203
-
-
Alonso, S.R.1
Ortiz, P.2
Pollan, M.3
Perez-Gomez, B.4
Sanchez, L.5
Acuna, M.J.6
Pajares, R.7
Martinez-Tello, F.J.8
Hortelano, C.M.9
Piris, M.A.10
Rodriguez-Peralto, J.L.11
-
59
-
-
20944437231
-
The gene expression signatures of melanoma progression
-
Haqq, C.; Nosrati, M.; Sudilovsky, D.; Crothers, J.; Khodabakhsh, D.; Pulliam, B.L.; Federman, S.; Miller, J.R., 3rd.; Allen, R.E.; Singer, M.I.; Leong, S.P.; Ljung, B.M.; Sagebiel, R.W.; Kashani-Sabet, M. The gene expression signatures of melanoma progression. Proc. Natl. Acad. Sci. USA, 2005, 102, 6092-6097.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 6092-6097
-
-
Haqq, C.1
Nosrati, M.2
Sudilovsky, D.3
Crothers, J.4
Khodabakhsh, D.5
Pulliam, B.L.6
Federman, S.7
Miller 3rd, J.R.8
Allen, R.E.9
Singer, M.I.10
Leong, S.P.11
Ljung, B.M.12
Sagebiel, R.W.13
Kashani-Sabet, M.14
-
60
-
-
35248899866
-
DNA microarray analyses of melanoma gene expression: A decade in the mines
-
Hoek, K.S. DNA microarray analyses of melanoma gene expression: a decade in the mines. Pigment Cell Res., 2007, 20, 466-484.
-
(2007)
Pigment Cell Res
, vol.20
, pp. 466-484
-
-
Hoek, K.S.1
-
61
-
-
33847397814
-
Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues
-
Jaeger, J.; Koczan, D.; Thiesen, H.J.; Ibrahim, S.M.; Gross, G.; Spang, R.; Kunz, M. Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues. Clin. Cancer Res., 2007, 13, 806-815.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 806-815
-
-
Jaeger, J.1
Koczan, D.2
Thiesen, H.J.3
Ibrahim, S.M.4
Gross, G.5
Spang, R.6
Kunz, M.7
-
62
-
-
33845783311
-
A gene expression signature associated with survival in metastatic melanoma
-
Mandruzzato, S.; Callegaro, A.; Turcatel, G.; Francescato, S.; Montesco, M.C.; Chiarion-Sileni, V.; Mocellin, S.; Rossi, C.R.; Bicciato, S.; Wang, E.; Marincola, F.M.; Zanovello, P. A gene expression signature associated with survival in metastatic melanoma. J. Transl. Med., 2006, 4, 50.
-
(2006)
J. Transl. Med
, vol.4
, pp. 50
-
-
Mandruzzato, S.1
Callegaro, A.2
Turcatel, G.3
Francescato, S.4
Montesco, M.C.5
Chiarion-Sileni, V.6
Mocellin, S.7
Rossi, C.R.8
Bicciato, S.9
Wang, E.10
Marincola, F.M.11
Zanovello, P.12
-
63
-
-
36949016275
-
Identification and functional characterization of ASK/Dbf4, a novel cell survival gene in cutaneous melanoma with prognostic relevance
-
Nambiar, S.; Mirmohammadsadegh, A.; Hassan, M.; Mota, R.; Marini, A.; Alaoui, A.; Tannapfel, A.; Hegemann, J.H.; Hengge, U.R. Identification and functional characterization of ASK/Dbf4, a novel cell survival gene in cutaneous melanoma with prognostic relevance. Carcinogenesis, 2007, 28, 2501-2510.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2501-2510
-
-
Nambiar, S.1
Mirmohammadsadegh, A.2
Hassan, M.3
Mota, R.4
Marini, A.5
Alaoui, A.6
Tannapfel, A.7
Hegemann, J.H.8
Hengge, U.R.9
-
64
-
-
35248864084
-
Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression
-
Ryu, B.; Kim, D.S.; Deluca, A.M.; Alani, R.M. Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression. PLoS ONE, 2007, 2, e594.
-
(2007)
PLoS ONE
, vol.2
-
-
Ryu, B.1
Kim, D.S.2
Deluca, A.M.3
Alani, R.M.4
-
65
-
-
0037307224
-
Gene expression profiling of melanocytic lesions
-
Seykora, J.T.; Jih, D.; Elenitsas, R.; Horng, W.H.; Elder, D.E. Gene expression profiling of melanocytic lesions. Am. J. Dermatopathol., 2003, 25, 6-11.
-
(2003)
Am. J. Dermatopathol
, vol.25
, pp. 6-11
-
-
Seykora, J.T.1
Jih, D.2
Elenitsas, R.3
Horng, W.H.4
Elder, D.E.5
-
66
-
-
3042665552
-
Expression of cell cycle inhibitor p27Kip1 and its inactivator Jab1 in melanocytic lesions
-
Ivan, D.; Diwan, A.H.; Esteva, F.J.; Prieto, V.G. Expression of cell cycle inhibitor p27Kip1 and its inactivator Jab1 in melanocytic lesions. Mod. Pathol., 2004, 17, 811-818.
-
(2004)
Mod. Pathol
, vol.17
, pp. 811-818
-
-
Ivan, D.1
Diwan, A.H.2
Esteva, F.J.3
Prieto, V.G.4
-
67
-
-
9944243708
-
Loss of heterozygosity at 12p13 and loss of p27KIP1 protein expression contribute to melanoma progression
-
Woenckhaus, C.; Fenic, I.; Giebel, J.; Hauser, S.; Failing, K.; Woenckhaus, J.; Dittberner, T.; Poetsch, M. Loss of heterozygosity at 12p13 and loss of p27KIP1 protein expression contribute to melanoma progression. Virchows Arch., 2004, 445, 491-497.
-
(2004)
Virchows Arch
, vol.445
, pp. 491-497
-
-
Woenckhaus, C.1
Fenic, I.2
Giebel, J.3
Hauser, S.4
Failing, K.5
Woenckhaus, J.6
Dittberner, T.7
Poetsch, M.8
-
68
-
-
38449110694
-
Mutation of the p16/CDKN2 gene and loss of heterozygosity in malignant mucosal melanoma and adenoid cystic carcinoma of the head and neck
-
Suzuki, N.; Onda, T.; Yamamoto, N.; Katakura, A.; Mizoe, J.E.; Shibahara, T. Mutation of the p16/CDKN2 gene and loss of heterozygosity in malignant mucosal melanoma and adenoid cystic carcinoma of the head and neck. Int. J. Oncol., 2007, 31, 1061-1067.
-
(2007)
Int. J. Oncol
, vol.31
, pp. 1061-1067
-
-
Suzuki, N.1
Onda, T.2
Yamamoto, N.3
Katakura, A.4
Mizoe, J.E.5
Shibahara, T.6
-
69
-
-
12244286059
-
Loss of p16 expression is associated with histological features of melanoma invasion
-
Pavey, S.J.; Cummings, M.C.; Whiteman, D.C.; Castellano, M.; Walsh, M.D.; Gabrielli, B.G.; Green, A.; Hayward, N.K. Loss of p16 expression is associated with histological features of melanoma invasion. Melanoma Res., 2002, 12, 539-547.
-
(2002)
Melanoma Res
, vol.12
, pp. 539-547
-
-
Pavey, S.J.1
Cummings, M.C.2
Whiteman, D.C.3
Castellano, M.4
Walsh, M.D.5
Gabrielli, B.G.6
Green, A.7
Hayward, N.K.8
-
70
-
-
35348988666
-
The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions
-
Demirkan, N.C.; Kesen, Z.; Akdag, B.; Larue, L.; Delmas, V. The effect of the sun on expression of beta-catenin, p16 and cyclin d1 proteins in melanocytic lesions. Clin. Exp. Dermatol., 2007, 32, 733-739.
-
(2007)
Clin. Exp. Dermatol
, vol.32
, pp. 733-739
-
-
Demirkan, N.C.1
Kesen, Z.2
Akdag, B.3
Larue, L.4
Delmas, V.5
-
71
-
-
63049118231
-
Centrosome-associated regulators of the G2/M checkpoint as targets for cancer therapy
-
Wang, Y.; Ji, P.; Liu, J.; Broaddus, R.R.; Xue, F.; Zhang, W. Centrosome-associated regulators of the G2/M checkpoint as targets for cancer therapy. Mol. Cancer, 2009, 8, 8.
-
(2009)
Mol. Cancer
, vol.8
, pp. 8
-
-
Wang, Y.1
Ji, P.2
Liu, J.3
Broaddus, R.R.4
Xue, F.5
Zhang, W.6
-
72
-
-
13544263599
-
The centrosomal protein RAS association domain family protein 1A (RASSF1A)-binding protein 1 regulates mitotic progression by recruiting RASSF1A to spindle poles
-
Song, M.S.; Chang, J.S.; Song, S.J.; Yang, T.H.; Lee, H.; Lim, D.S. The centrosomal protein RAS association domain family protein 1A (RASSF1A)-binding protein 1 regulates mitotic progression by recruiting RASSF1A to spindle poles. J. Biol. Chem., 2005, 280, 3920-3927.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 3920-3927
-
-
Song, M.S.1
Chang, J.S.2
Song, S.J.3
Yang, T.H.4
Lee, H.5
Lim, D.S.6
-
73
-
-
43249083502
-
The RASSF1A tumor suppressor restrains anaphase-promoting complex/ cyclosome activity during the G1/S phase transition to promote cell cycle progression in human epithelial cells
-
Whitehurst, A.W.; Ram, R.; Shivakumar, L.; Gao, B.; Minna, J.D.; White, M.A. The RASSF1A tumor suppressor restrains anaphase-promoting complex/ cyclosome activity during the G1/S phase transition to promote cell cycle progression in human epithelial cells. Mol. Cell Biol., 2008, 28, 3190-3197.
-
(2008)
Mol. Cell Biol
, vol.28
, pp. 3190-3197
-
-
Whitehurst, A.W.1
Ram, R.2
Shivakumar, L.3
Gao, B.4
Minna, J.D.5
White, M.A.6
-
74
-
-
33645050117
-
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis
-
Oh, H.J.; Lee, K.K.; Song, S.J.; Jin, M.S.; Song, M.S.; Lee, J.H.; Im, C.R.; Lee, J.O.; Yonehara, S.; Lim, D.S. Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. Cancer Res., 2006, 66, 2562-2569.
-
(2006)
Cancer Res
, vol.66
, pp. 2562-2569
-
-
Oh, H.J.1
Lee, K.K.2
Song, S.J.3
Jin, M.S.4
Song, M.S.5
Lee, J.H.6
Im, C.R.7
Lee, J.O.8
Yonehara, S.9
Lim, D.S.10
-
75
-
-
68749094107
-
Molecular dissection of the RAS/RAF/MAPK pathway in primary and metastatic melanoma
-
Rother, J.; Bailey, J.; Alvarado, G.; Prieto, V.; Lazar, A.; Jones, D.; W-J, H. Molecular dissection of the RAS/RAF/MAPK pathway in primary and metastatic melanoma. J. Clin. Oncol., 2006, 24, 8050.
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 8050
-
-
Rother, J.1
Bailey, J.2
Alvarado, G.3
Prieto, V.4
Lazar, A.5
Jones, D.6
W-J, H.7
-
76
-
-
36849052501
-
Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation
-
Rong, R.; Jiang, L.Y.; Sheikh, M.S.; Huang, Y. Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation. Oncogene, 2007, 26, 7700-7708.
-
(2007)
Oncogene
, vol.26
, pp. 7700-7708
-
-
Rong, R.1
Jiang, L.Y.2
Sheikh, M.S.3
Huang, Y.4
-
77
-
-
50249095737
-
Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes
-
Haruta, M.; Matsumoto, Y.; Izumi, H.; Watanabe, N.; Fukuzawa, M.; Matsuura, S.; Kaneko, Y. Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes. Mol. Carcinog., 2008, 47: 660-666.
-
(2008)
Mol. Carcinog
, vol.47
, pp. 660-666
-
-
Haruta, M.1
Matsumoto, Y.2
Izumi, H.3
Watanabe, N.4
Fukuzawa, M.5
Matsuura, S.6
Kaneko, Y.7
-
78
-
-
1642602695
-
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex
-
Song, M.S.; Song, S.J.; Ayad, N.G.; Chang, J.S.; Lee, J.H.; Hong, H.K.; Lee, H.; Choi, N.; Kim, J.; Kim, H.; Kim, J.W.; Choi, E.J.; Kirschner, M.W.; Lim, D.S. The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat. Cell Biol., 2004, 6, 129-137.
-
(2004)
Nat. Cell Biol
, vol.6
, pp. 129-137
-
-
Song, M.S.1
Song, S.J.2
Ayad, N.G.3
Chang, J.S.4
Lee, J.H.5
Hong, H.K.6
Lee, H.7
Choi, N.8
Kim, J.9
Kim, H.10
Kim, J.W.11
Choi, E.J.12
Kirschner, M.W.13
Lim, D.S.14
-
79
-
-
59149085059
-
Multidrug resistance decreases with mutations of melanosomal regulatory genes
-
Xie, T.; Nguyen, T.; Hupe, M.; Wei, M.L. Multidrug resistance decreases with mutations of melanosomal regulatory genes. Cancer Res., 2009, 69, 992-999.
-
(2009)
Cancer Res
, vol.69
, pp. 992-999
-
-
Xie, T.1
Nguyen, T.2
Hupe, M.3
Wei, M.L.4
-
80
-
-
33745615832
-
Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas
-
Chen, K.G.; Valencia, J.C.; Lai, B.; Zhang, G.; Paterson, J.K.; Rouzaud, F.; Berens, W.; Wincovitch, S.M.; Garfield, S.H.; Leapman, R.D.; Hearing, V.J.; Gottesman, M.M. Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc. Natl. Acad. Sci. USA, 2006, 103, 9903-9907.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 9903-9907
-
-
Chen, K.G.1
Valencia, J.C.2
Lai, B.3
Zhang, G.4
Paterson, J.K.5
Rouzaud, F.6
Berens, W.7
Wincovitch, S.M.8
Garfield, S.H.9
Leapman, R.D.10
Hearing, V.J.11
Gottesman, M.M.12
-
81
-
-
59449085721
-
Genomic and molecular profiling predicts response to temozolomide in melanoma
-
Augustine, C.K.; Yoo, J.S.; Potti, A.; Yoshimoto, Y.; Zipfel, P.A.; Friedman, H.S.; Nevins, J.R.; Ali-Osman, F.; Tyler, D.S. Genomic and molecular profiling predicts response to temozolomide in melanoma. Clin. Cancer Res., 2009, 15, 502-510.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 502-510
-
-
Augustine, C.K.1
Yoo, J.S.2
Potti, A.3
Yoshimoto, Y.4
Zipfel, P.A.5
Friedman, H.S.6
Nevins, J.R.7
Ali-Osman, F.8
Tyler, D.S.9
-
82
-
-
48149100988
-
Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells
-
Gao, K.; Lockwood, W.W.; Li, J.; Lam, W.; Li, G. Genomic analyses identify gene candidates for acquired irinotecan resistance in melanoma cells. Int. J. Oncol., 2008, 32, 1343-1349.
-
(2008)
Int. J. Oncol
, vol.32
, pp. 1343-1349
-
-
Gao, K.1
Lockwood, W.W.2
Li, J.3
Lam, W.4
Li, G.5
-
83
-
-
53249090604
-
WNT5A expression increases during melanoma progression and correlates with outcome
-
Da Forno, P.D.; Pringle, J.H.; Hutchinson, P.; Osborn, J.; Huang, Q.; Potter, L.; Hancox, R.A.; Fletcher, A.; Saldanha, G.S. WNT5A expression increases during melanoma progression and correlates with outcome. Clin. Cancer Res., 2008, 14, 5825-5832.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 5825-5832
-
-
Da Forno, P.D.1
Pringle, J.H.2
Hutchinson, P.3
Osborn, J.4
Huang, Q.5
Potter, L.6
Hancox, R.A.7
Fletcher, A.8
Saldanha, G.S.9
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