Aplysia cys-loop glutamate-gated chloride channels reveal convergent evolution of ligand specificity

Journal of Molecular Evolution

Volumn 69, Issue 2, 2009, Pages 125-141

  Kehoe, Jacsue ^a,b   Buldakova, Svetlana ^c   Acher, Francine ^d   Dent, Joseph ^e   Bregestovski, Piotr ^c   Bradley, Jonathan ^a  

^a CNRS   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Turing Center for Living Systems CENTURI Aix Marseille University   (France)

^d Université Paris Descartes   (France)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

Aplysia; Chloride channels; Glutamate; Glycine; Glycine binding pocket motif; LGICs; Phylogeny

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; AMINO ACID; ANTIPARASITIC AGENT; BETA ALANINE; CHLORIDE CHANNEL; COMPLEMENTARY DNA; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLYCINE; GLYCINE RECEPTOR; HISTAMINE; INSECTICIDE; ION CHANNEL; IVERMECTIN; LIGAND; LIGAND GATED ION CHANNEL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANNELID WORM; APLYSIA; ARTHROPOD; ARTICLE; CHO CELL; CLADISTICS; COELENTERATE; CONVERGENT EVOLUTION; CRUSTACEA; ECHINODERM; GENOME; LIGAND BINDING; MOLLUSC; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; SEQUENCE DATABASE; VERTEBRATE;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; APLYSIA; CHLORIDE CHANNELS; CYSTEINE; EVOLUTION, MOLECULAR; GLYCINE; ION CHANNEL GATING; IVERMECTIN; LIGANDS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN SUBUNITS; RECEPTORS, GABA-A; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

ANNELIDA; APLYSIA; APLYSIA CALIFORNICA; ARTHROPODA; BILATERIA; CHORDATA; CNIDARIA; CRUSTACEA; ECDYSOZOA; ECHINODERMATA; NEMATODA; VERTEBRATA;

EID: 68449095532     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-009-9256-z     Document Type: Article

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