Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter

Journal of Biological Chemistry

Volumn 281, Issue 21, 2006, Pages 14875-14881

  Sunesen, Morten ^a,b   De Carvalho, Lia Prado ^a   Dufresne, Virginie ^a   Grailhe, Regis ^a   Savatier Duclert, Nathalie ^a   Gibor, Gilad ^c   Peretz, Asher ^c   Attali, Bernard ^c   Changeux, Jean Pierre ^a   Paas, Yoav ^a,c  

^a INSTITUT PASTEUR   (France)

^b Sophion Bioscience A/S   (Denmark)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; DEHYDRATION; NEGATIVE IONS; ORGANIC ACIDS; POSITIVE IONS;

CAENORHABDITIS ELEGANS; CATIONIC PERMEABILITY RATIOS; GLUTAMATE-GATED CHLORIDE; TRANSMEMBRANE SEGMENTS;

MUTAGENESIS;

4 AMINOBUTYRIC ACID; ANION; CATION; CHLORIDE CHANNEL; CHOLINERGIC RECEPTOR; GLUTAMATE GATED CHLORIDE CHANNEL; GLYCINE; ION CHANNEL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; ION CURRENT; MEMBRANE PERMEABILITY; MICROCHIMERISM; PRIORITY JOURNAL; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CHLORIDE CHANNELS; CHLORIDES; ELECTROPHYSIOLOGY; GLUTAMATES; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

CAENORHABDITIS ELEGANS; INVERTEBRATA; VERTEBRATA;

EID: 33744959428     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511657200     Document Type: Article

References (41)

1. Changeux, J.-P. (1990) FIDIA Res. Found. Neurosci. Award Lec. 4, 21-168
2. Smith, G. B., and Olsen, R. W. (1995) Trends Pharmacol. Sci. 16, 162-168
3. Bargmann, C. I. (1998) Science 282, 2028-2033
4. Taylor, P., Osaka, H., Molles, B., Keller, S. H., and Malany, S. (2000) in Neuronal Nicotinic Receptors (Handbook of Experimental Pharmacoloy), Vol. 144, pp. 79-100, Springer Verlag, Berlin
5. Karlin, A. (2002) Nat. Rev. Neurosci. 3, 102-114
6. Laube, B., Maksay, G., Schemm, R., and Betz, H. (2002) Trends Pharmacol. Sci. 23, 519-527
7. Fuchs, S., Kasher, R., Balass, M., Scherf, T., Harel, M., Fridkin, M., Sussman, J. L., and Katchalski-Katzir, E. (2003) Ann. N. Y. Acad. Sci. 998, 93-100
8. Lester, H. A., Dibas, M. I., Dahan, D. S., Leite, J. F., and Dougherty, D. A. (2004) Trends Neurosci. 27, 329-336
9. Keramidas, A., Moorhouse, A. J., Schofield, P. R., and Barry, P. H. (2004) Prog. Biophys. Mol. Biol. 86, 161-204
10. Galzi, J. L., Devillers-Thiery, A., Hussy, N., Bertrand, S., Changeux, J. P., and Bertrand, D. (1992) Nature 359, 500-505
11. Keramidas, A., Moorhouse, A. J., French, C. R., Schofield, P. R., and Barry, P. H. (2000) Biophys. J. 79, 247-259
12. Gunthorpe, M. J., and Lummis, S. C. (2001) J. Biol. Chem. 276, 10977-10983
13. Menard, C., Horvitz, H. R., and Cannon, S. (2005) J. Biol. Chem. 280, 27502-27507
14. Corringer, P. J., Bertrand, S., Galzi, J. L., Devillers-Thiery, A., Changeux, J. P., and Bertrand, D. (1999) Neuron 22, 831-843
15. Keramidas, A., Moorhouse, A. J., Pierce, K. D., Schofield, P. R., and Barry, P. H. (2002) J. Gen. Physiol. 119, 393-410
16. Wotring, V. E., Miller, T. S., and Weiss, D. S. (2003) J. Physiol. (Lond.) 548, 527-540
17. Lee, D. J., Keramidas, A., Moorhouse, A. J., Schofield, P. R., and Barry, P. H. (2003) Neurosci. Lett. 351, 196-200
18. Cully, D. F., Vassilatis, D. K., Liu, K. K., Paress, P. S., Van der Ploeg, L. H., Schaeffer, J. M., and Arena, J. P. (1994) Nature 371, 707-711
19. Eisele, J. L., Bertrand, S., Galzi, J. L., Devillers-Thiery, A., Changeux, J. P., and Bertrand, D. (1993) Nature 366, 479-483
20. Paas, Y., Gibor, G., Grailhe, R., Savatier-Duclert, N., Dufresne, V., Sunesen, M., de Carvalho, L. P., Changeux, J. P., and Attali, B. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15877-15882
21. Barry, P. H. (1994) J. Neurosci. Methods 51, 107-116
22. MacInnes, D. A. (1961) The Principles of Electrochemistry, Dover Publications, Inc., New York
23. Miyazawa, A., Fujiyoshi, Y., and Unwin, N. (2003) Nature 423, 949-955
24. Thompson, A. J., and Lummis, S. C. (2003) Br. J. Pharmacol. 140, 359-365
25. Moorhouse, A. J., Keramidas, A., Zaykin, A., Schofield, P. R., and Barry, P. H. (2002) J. Gen. Physiol. 119, 411-425
26. Imoto, K., Busch, C., Sakmann, B., Mishina, M., Konno, T., Nakai, J., Bujo, H., Mori, Y., Fukuda, K., and Numa, S. (1988) Nature 335, 645-648
27. Imoto, K., Konno, T., Nakai, J., Wang, F., Mishina, M., and Numa, S. (1991) FEBS Lett. 289, 193-200
28. Villarroel, A., and Sakmann, B. (1992) Biophys. J. 62, 196-208
29. Bormann, J., Rundstrom, N., Betz, H., and Langosch, D. (1993) EMBO J. 12, 3729-3737
30. Wilson, G. G., and Karlin, A. (1998) Neuron 20, 1269-1281
31. Carland, J. E., Moorhouse, A. J., Barry, P. H., Johnston, G. A., and Chebib, M. (2004) J. Biol. Chem. 279, 54153-54160
32. Jensen, M. L., Pedersen, L. N., Timmermann, D. B., Schousboe, A., and Ahring, P. K. (2005) J. Neurochem. 92, 962-972
33. Jensen, M. L., Timmermann, D. B., Johansen, T. H., Schousboe, A., Varming, T., and Ahring, P. K. (2002) J. Biol. Chem. 277, 41438-41447
34. Wilson, G. G., Pascual, J. M., Brooijmans, N., Murray, D., and Karlin, A. (2000) J. Gen. Physiol. 115, 93-106
35. Bormann, J., Hamill, O. P., and Sakmann, B. (1987) J. Physiol. (Lond.) 385, 243-286
36. Fatima-Shad, K., and Barry, P. H. (1993) Proc. R. Soc. Lond. B Biol. Sci. 253, 69-75
37. Rundstrom, N., Schmieden, V., Betz, H., Bormann, J., and Langosch, D. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8950-8954
38. Wotring, V. E., Chang, Y., and Weiss, D. S. (1999) J. Physiol. (Lond.) 521, 327-336
39. Matthews, B. W., Nicholson, H., and Becktel, W. J. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6663-6667
40. Dutzler, R., Campbell, E. B., Cadene, M., Chait, B. T., and MacKinnon, R. (2002) Nature 415, 287-294
41. Pitzer, K. S. (1991) Activity Coefficients in Electrolyte Solutions, 2nd Ed., pp. 75-153, CRC Press, Boca Raton, FL