-
1
-
-
0033010373
-
The IL-4 receptor: Signaling mechanisms and biologic functions
-
Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE: The IL-4 receptor: signaling mechanisms and biologic functions. Annu Rev Immunol 1999, 17:701-738
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 701-738
-
-
Nelms, K.1
Keegan, A.D.2
Zamorano, J.3
Ryan, J.J.4
Paul, W.E.5
-
2
-
-
0033949735
-
The role of interleukin-13 in infectious diseases and allergy
-
Brombacher F: The role of interleukin-13 in infectious diseases and allergy. Bioessays 2000, 22:646-656
-
(2000)
Bioessays
, vol.22
, pp. 646-656
-
-
Brombacher, F.1
-
3
-
-
36448983633
-
Protective immune mechanisms in helminth infection
-
Anthony RM, Rutitzky LI, Urban JF, Jr., Stadecker MJ, Gause WC: Protective immune mechanisms in helminth infection. Nat Rev Immunol 2007, 7:975-987
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 975-987
-
-
Anthony, R.M.1
Rutitzky, L.I.2
Urban Jr., J.F.3
Stadecker, M.J.4
Gause, W.C.5
-
4
-
-
0034163317
-
Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent
-
Fallon PG, Richardson EJ, McKenzie GJ, McKenzie AN: Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: iL-13 is a profibrotic agent. J Immunol 2000, 164:2585-2591
-
(2000)
J Immunol
, vol.164
, pp. 2585-2591
-
-
Fallon, P.G.1
Richardson, E.J.2
McKenzie, G.J.3
McKenzie, A.N.4
-
5
-
-
2442717844
-
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology
-
Herbert DR, Holscher C, Mohrs M, Arendse B, Schwegmann A, Radwanska M, Leeto M, Kirsch R, Hall P, Mossmann H, Claussen B, Forster I, Brombacher F: Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity 2004, 20:623-635
-
(2004)
Immunity
, vol.20
, pp. 623-635
-
-
Herbert, D.R.1
Holscher, C.2
Mohrs, M.3
Arendse, B.4
Schwegmann, A.5
Radwanska, M.6
Leeto, M.7
Kirsch, R.8
Hall, P.9
Mossmann, H.10
Claussen, B.11
Forster, I.12
Brombacher, F.13
-
6
-
-
0034660272
-
IL-10 and the dangers of immune polarization: Excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis
-
Hoffmann KF, Cheever AW, Wynn TA: IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis. J Immunol 2000, 164:6406-6416
-
(2000)
J Immunol
, vol.164
, pp. 6406-6416
-
-
Hoffmann, K.F.1
Cheever, A.W.2
Wynn, T.A.3
-
7
-
-
0029787798
-
IL-4-deficient Balb/c mice resist infection with Leishmania major
-
Kopf M, Brombacher F, Kohler G, Kienzle G, Widmann KH, Lefrang K, Humborg C, Ledermann B, Solbach W: IL-4-deficient Balb/c mice resist infection with Leishmania major. J Exp Med 1996, 184:1127-1136
-
(1996)
J Exp Med
, vol.184
, pp. 1127-1136
-
-
Kopf, M.1
Brombacher, F.2
Kohler, G.3
Kienzle, G.4
Widmann, K.H.5
Lefrang, K.6
Humborg, C.7
Ledermann, B.8
Solbach, W.9
-
8
-
-
0030023112
-
Susceptibility to Leishmania major infection in interleukin-4-deficient mice
-
Noben-Trauth N, Kropf P, Muller I: Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science 1996, 271:987-990
-
(1996)
Science
, vol.271
, pp. 987-990
-
-
Noben-Trauth, N.1
Kropf, P.2
Muller, I.3
-
9
-
-
0033564686
-
Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signaling
-
Mohrs M, Ledermann B, Kohler G, Dorfmuller A, Gessner A, Brombacher F: Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic Leishmaniasis reveal a protective role for IL-13 receptor signaling. J Immunol 1999, 162:7302-7308
-
(1999)
J Immunol
, vol.162
, pp. 7302-7308
-
-
Mohrs, M.1
Ledermann, B.2
Kohler, G.3
Dorfmuller, A.4
Gessner, A.5
Brombacher, F.6
-
10
-
-
38649137731
-
Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system
-
LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC: Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell 2008, 132:259-272
-
(2008)
Cell
, vol.132
, pp. 259-272
-
-
LaPorte, S.L.1
Juo, Z.S.2
Vaclavikova, J.3
Colf, L.A.4
Qi, X.5
Heller, N.M.6
Keegan, A.D.7
Garcia, K.C.8
-
11
-
-
0036831673
-
The immunology of susceptibility and resistance to Leishmania major in mice
-
Sacks D, Noben-Trauth N: The immunology of susceptibility and resistance to Leishmania major in mice. Nat Rev Immunol 2002, 2:845-858
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 845-858
-
-
Sacks, D.1
Noben-Trauth, N.2
-
12
-
-
0025818157
-
Helper T-cell subsets in mouse Leishmaniasis: Induction, expansion and effector function
-
Locksley RM, Scott P: Helper T-cell subsets in mouse Leishmaniasis: induction, expansion and effector function. Immunol Today 1991, 12:A58-61
-
(1991)
Immunol Today
, vol.12
-
-
Locksley, R.M.1
Scott, P.2
-
13
-
-
0028933795
-
The regulation of immunity to Leishmania major
-
Reiner SL, Locksley RM: The regulation of immunity to Leishmania major. Annu Rev Immunol 1995, 13:151-177
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 151-177
-
-
Reiner, S.L.1
Locksley, R.M.2
-
14
-
-
0034106507
-
Interleukin-4 receptor alpha-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection
-
Mohrs M, Holscher C, Brombacher F: Interleukin-4 receptor alpha-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection. Infect Immun 2000, 68:1773-1780
-
(2000)
Infect Immun
, vol.68
, pp. 1773-1780
-
-
Mohrs, M.1
Holscher, C.2
Brombacher, F.3
-
15
-
-
30744477705
-
Impairment of alternative macrophage activation delays cutaneous Leishmaniasis in nonhealing BALB/c mice
-
Holscher C, Arendse B, Schwegmann A, Myburgh E, Brombacher F: Impairment of alternative macrophage activation delays cutaneous Leishmaniasis in nonhealing BALB/c mice. J Immunol 2006, 176:1115-1121
-
(2006)
J Immunol
, vol.176
, pp. 1115-1121
-
-
Holscher, C.1
Arendse, B.2
Schwegmann, A.3
Myburgh, E.4
Brombacher, F.5
-
16
-
-
34249658382
-
Deletion of IL-4R alpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection
-
Radwanska M, Cutler AJ, Hoving JC, Magez S, Holscher C, Bohms A, Arendse B, Kirsch R, Hunig T, Alexander J, Kaye P, Brombacher F: Deletion of IL-4R alpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection. PLoS Pathog 2007, 3:e68
-
(2007)
PLoS Pathog
, vol.3
-
-
Radwanska, M.1
Cutler, A.J.2
Hoving, J.C.3
Magez, S.4
Holscher, C.5
Bohms, A.6
Arendse, B.7
Kirsch, R.8
Hunig, T.9
Alexander, J.10
Kaye, P.11
Brombacher, F.12
-
18
-
-
3543107212
-
Fibrotic disease and the T(H)1/T(H)2 paradigm
-
Wynn TA: Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol 2004, 4:583-594
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 583-594
-
-
Wynn, T.A.1
-
19
-
-
0033168893
-
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile
-
Jankovic D, Kullberg MC, Noben-Trauth N, Caspar P, Ward JM, Cheever AW, Paul WE, Sher A: Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. J Immunol 1999, 163:337-342
-
(1999)
J Immunol
, vol.163
, pp. 337-342
-
-
Jankovic, D.1
Kullberg, M.C.2
Noben-Trauth, N.3
Caspar, P.4
Ward, J.M.5
Cheever, A.W.6
Paul, W.E.7
Sher, A.8
-
20
-
-
0032519993
-
Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response
-
Kaplan MH, Whitfield JR, Boros DL, Grusby MJ: Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response. J Immunol 1998, 160:1850-1856
-
(1998)
J Immunol
, vol.160
, pp. 1850-1856
-
-
Kaplan, M.H.1
Whitfield, J.R.2
Boros, D.L.3
Grusby, M.J.4
-
21
-
-
38749112502
-
TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis
-
Leeto M, Herbert DR, Marillier R, Schwegmann A, Fick L, Brombacher F: TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis. Am J Pathol 2006, 169:1701-1712
-
(2006)
Am J Pathol
, vol.169
, pp. 1701-1712
-
-
Leeto, M.1
Herbert, D.R.2
Marillier, R.3
Schwegmann, A.4
Fick, L.5
Brombacher, F.6
-
22
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, Perez-Melgosa M, Sweetser MT, Schlissel MS, Nguyen S, Cherry SR, Tsai JH, Tucker SM, Weaver WM, Kelso A, Jaenisch R, Wilson CB: A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 2001, 15:763-774
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Perez-Melgosa, M.7
Sweetser, M.T.8
Schlissel, M.S.9
Nguyen, S.10
Cherry, S.R.11
Tsai, J.H.12
Tucker, S.M.13
Weaver, W.M.14
Kelso, A.15
Jaenisch, R.16
Wilson, C.B.17
-
23
-
-
0025055740
-
Disruption of thymocyte development and lymphomagenesis induced by SV40 T-antigen
-
Garvin AM, Abraham KM, Forbush KA, Farr AG, Davison BL, Perlmutter RM: Disruption of thymocyte development and lymphomagenesis induced by SV40 T-antigen. Int Immunol 1990, 2:173-180
-
(1990)
Int Immunol
, vol.2
, pp. 173-180
-
-
Garvin, A.M.1
Abraham, K.M.2
Forbush, K.A.3
Farr, A.G.4
Davison, B.L.5
Perlmutter, R.M.6
-
24
-
-
0030002111
-
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
-
Mattner F, Magram J, Ferrante J, Launois P, Di Padova K, Behin R, Gately MK, Louis JA, Alber G: Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol 1996, 26:1553-1559
-
(1996)
Eur J Immunol
, vol.26
, pp. 1553-1559
-
-
Mattner, F.1
Magram, J.2
Ferrante, J.3
Launois, P.4
Di Padova, K.5
Behin, R.6
Gately, M.K.7
Louis, J.A.8
Alber, G.9
-
25
-
-
0014838907
-
Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs
-
Boros DL, Warren KS: Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs. J Exp Med 1970, 132:488-507
-
(1970)
J Exp Med
, vol.132
, pp. 488-507
-
-
Boros, D.L.1
Warren, K.S.2
-
26
-
-
0027934360
-
Determination of arginase activity in macrophages: A micromethod
-
Corraliza IM, Campo ML, Soler G, Modolell M: Determination of arginase activity in macrophages: a micromethod. J Immunol Methods 1994, 174:231-235
-
(1994)
J Immunol Methods
, vol.174
, pp. 231-235
-
-
Corraliza, I.M.1
Campo, M.L.2
Soler, G.3
Modolell, M.4
-
27
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu H, Marth JD, Orban PC, Mossmann H, Rajewsky K: Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science 1994, 265:103-106
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
28
-
-
0028201726
-
Acquisition of lymphokine-producing phenotype by CD4+ T cells
-
Seder RA, Paul WE: Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994, 12:635-673
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 635-673
-
-
Seder, R.A.1
Paul, W.E.2
-
29
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN: Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 1996, 380:630-633
-
(1996)
Nature
, vol.380
, pp. 630-633
-
-
Shimoda, K.1
van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chu, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.10
Doherty, P.C.11
Grosveld, G.12
Paul, W.E.13
Ihle, J.N.14
-
30
-
-
0029807339
-
Conditional gene targeting
-
Rajewsky K, Gu H, Kuhn R, Betz UA, Muller W, Roes J, Schwenk F: Conditional gene targeting. J Clin Invest 1996, 98:600-603
-
(1996)
J Clin Invest
, vol.98
, pp. 600-603
-
-
Rajewsky, K.1
Gu, H.2
Kuhn, R.3
Betz, U.A.4
Muller, W.5
Roes, J.6
Schwenk, F.7
-
32
-
-
33749425534
-
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
-
Gallina G, Dolcetti L, Serafini P, De Santo C, Marigo I, Colombo MP, Basso G, Brombacher F, Borrello I, Zanovello P, Bicciato S, Bronte V: Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 2006, 116:2777-2790
-
(2006)
J Clin Invest
, vol.116
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
De Santo, C.4
Marigo, I.5
Colombo, M.P.6
Basso, G.7
Brombacher, F.8
Borrello, I.9
Zanovello, P.10
Bicciato, S.11
Bronte, V.12
-
33
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Eagle AR, Vats D, Brombacher F, Ferrante AW, Chawla A: Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 2007, 447:1116-1120
-
(2007)
Nature
, vol.447
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
34
-
-
58149200168
-
IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis
-
Herbert DR, Orekov T, Perkins C, Finkelman FD: IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis. J Immunol 2008, 181:7214-7220
-
(2008)
J Immunol
, vol.181
, pp. 7214-7220
-
-
Herbert, D.R.1
Orekov, T.2
Perkins, C.3
Finkelman, F.D.4
-
35
-
-
0027184993
-
Evolving T cell responses in murine schistosomiasis. Th2 cells mediate secondary granulomatous hypersensitivity and are regulated by CD8+ T cells in vivo
-
Chensue SW, Warmington KS, Hershey SD, Terebuh PD, Othman M, Kunkel SL: Evolving T cell responses in murine schistosomiasis. Th2 cells mediate secondary granulomatous hypersensitivity and are regulated by CD8+ T cells in vivo. J Immunol 1993, 151:1391-1400
-
(1993)
J Immunol
, vol.151
, pp. 1391-1400
-
-
Chensue, S.W.1
Warmington, K.S.2
Hershey, S.D.3
Terebuh, P.D.4
Othman, M.5
Kunkel, S.L.6
-
36
-
-
0024506648
-
Characterization of granuloma T lymphocyte function from Schistosoma mansoni-infected mice
-
Ragheb S, Boros DL: Characterization of granuloma T lymphocyte function from Schistosoma mansoni-infected mice. J Immunol 1989, 142:3239-3246
-
(1989)
J Immunol
, vol.142
, pp. 3239-3246
-
-
Ragheb, S.1
Boros, D.L.2
-
37
-
-
0030968979
-
Unimpaired down-modulation of the hepatic granulomatous response in CD8 T-cell- and gamma interferon-deficient mice chronically infected with Schistosoma mansoni
-
Yap G, Cheever A, Caspar P, Jankovic D, Sher A: Unimpaired down-modulation of the hepatic granulomatous response in CD8 T-cell- and gamma interferon-deficient mice chronically infected with Schistosoma mansoni. Infect Immun 1997, 65:2583-2586
-
(1997)
Infect Immun
, vol.65
, pp. 2583-2586
-
-
Yap, G.1
Cheever, A.2
Caspar, P.3
Jankovic, D.4
Sher, A.5
|