A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-β

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 17, 2009, Pages 4952-4957

  Reinke, Ashley A ^a   Seh, Han Yiau ^a   Gestwicki, Jason E ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Alzheimer's disease; Fluorescence; Neurodegeneration; Protein misfolding; Thioflavin T

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; CONGO RED; INDOLE; OLIGOMER; THIOFLAVINE;

ARTICLE; DENATURATION; FLUORESCENCE; GEL ELECTROPHORESIS; REPRODUCIBILITY; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

AMYLOID BETA-PEPTIDES; COLORING AGENTS; CONGO RED; FLUORESCENT DYES; INDOLES; SPECTROMETRY, FLUORESCENCE; THIAZOLES;

EID: 68349160554     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.07.082     Document Type: Article

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