Novel γ-aminobutyric acid ρ1 receptor antagonists; synthesis, pharmacological activity and structure-activity relationships

Journal of Medicinal Chemistry

Volumn 51, Issue 13, 2008, Pages 3825-3840

  Kumar, Rohan J ^a   Chebib, Mary ^a   Hibbs, David E ^a   Kim, Hye Lim ^a   Johnston, Graham A R ^b   Salam, Noeris K ^a   Hanrahan, Jane R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b University of Sydney   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 1 CYCLOPENT 1 ENYL(BUTYL)PHOSPHINIC ACID; 4 AMINO 1 CYCLOPENT 1 ENYL(METHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID C RECEPTOR; 4 AMINOBUTYRIC ACID C RECEPTOR BLOCKING AGENT; GABA C RECEPTOR RHO1; LIGAND; PHOSPHINIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PHARMACOPHORE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; FEMALE; GABA ANTAGONISTS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OOCYTES; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 46849096458     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm7015842     Document Type: Article

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