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Volumn 120, Issue 1, 1997, Pages 53-63

Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists

Author keywords

Ah receptor agonist; Antitumorigenicity; Mammary

Indexed keywords

1,3,8 TRICHLORO 6 METHYLDIBENZOFURAN; 6 CYCLOHEXYL 1,3,8 TRICHLORODIBENZOFURAN; 7,12 DIMETHYLBENZ[A]ANTHRACENE; 8 METHYL 1,3,6 TRICHLORODIBENZOFURAN; ANTIESTROGEN; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; BENZOFURAN DERIVATIVE; ETHOXYRESORUFIN DEETHYLASE; LIVER ENZYME; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 0030731436     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00299-1     Document Type: Article
Times cited : (62)

References (70)
  • 1
    • 0023766378 scopus 로고
    • Breast cancer epidemiology
    • Kelsey J.L., Berkowitz G.S. Breast cancer epidemiology. Cancer Res. 48:1988;5615-5623.
    • (1988) Cancer Res. , vol.48 , pp. 5615-5623
    • Kelsey, J.L.1    Berkowitz, G.S.2
  • 2
    • 0026700911 scopus 로고
    • Endocrine therapy for advanced breast cancer - A review
    • Muss H.B. Endocrine therapy for advanced breast cancer - a review. Breast Cancer Res. Treat. 21:1992;15-26.
    • (1992) Breast Cancer Res. Treat. , vol.21 , pp. 15-26
    • Muss, H.B.1
  • 4
    • 0025338591 scopus 로고
    • Development of antiestrogens and their use in breast cancer: Eighth Cain Memorial Award Lecture
    • Lerner L.J., Jordan V.C. Development of antiestrogens and their use in breast cancer: eighth Cain Memorial Award Lecture. Cancer Res. 50:1990;4177-4189.
    • (1990) Cancer Res. , vol.50 , pp. 4177-4189
    • Lerner, L.J.1    Jordan, V.C.2
  • 5
    • 0027172047 scopus 로고
    • A current view of tamoxifen for the treatment and prevention of breast cancer
    • Jordan V.C. A current view of tamoxifen for the treatment and prevention of breast cancer. Br. J. Pharmacol. 110:1993;507-517.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 507-517
    • Jordan, V.C.1
  • 6
    • 0000524684 scopus 로고
    • On the treatment of inoperable cases of carcinoma of the mamma; Suggestions for a new method of treatment with illustrative cases
    • Beatson G.T. On the treatment of inoperable cases of carcinoma of the mamma; suggestions for a new method of treatment with illustrative cases. Lancet. 2:1986;104-107.
    • (1986) Lancet , vol.2 , pp. 104-107
    • Beatson, G.T.1
  • 7
    • 0025242415 scopus 로고
    • Endocrine pharmacology of antiestrogens
    • Jordan V.C., Murphy C.S. Endocrine pharmacology of antiestrogens. Endocrine Rev. 11:1990;578-610.
    • (1990) Endocrine Rev. , vol.11 , pp. 578-610
    • Jordan, V.C.1    Murphy, C.S.2
  • 9
    • 0025084510 scopus 로고
    • Inhibition of estrogen receptor-DNA binding by the 'pure' antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization
    • Fawell S.E., White R., Hoare S., Sydenham M., Page M., Parker M.G. Inhibition of estrogen receptor-DNA binding by the 'pure' antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization. Proc. Natl. Acad. Sci. USA. 87:1990;6883-6887.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 6883-6887
    • Fawell, S.E.1    White, R.2    Hoare, S.3    Sydenham, M.4    Page, M.5    Parker, M.G.6
  • 10
    • 0026560435 scopus 로고
    • Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover
    • Dauvois S., Danielian P.S., White R., Parker M.G. Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover. Proc. Natl. Acad. Sci. USA. 89:1992;4037-4041.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4037-4041
    • Dauvois, S.1    Danielian, P.S.2    White, R.3    Parker, M.G.4
  • 11
    • 0027279120 scopus 로고
    • MCF7/LCC2: A 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780
    • Brunner N., Frandsen T.L., Holst-Hansen C., Bei M., Thompson E.W., Wakeling A.E., Lippman M.E., Clarke R. MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780. Cancer Res. 53:1993;3229-3232.
    • (1993) Cancer Res. , vol.53 , pp. 3229-3232
    • Brunner, N.1    Frandsen, T.L.2    Holst-Hansen, C.3    Bei, M.4    Thompson, E.W.5    Wakeling, A.E.6    Lippman, M.E.7    Clarke, R.8
  • 12
    • 0030055509 scopus 로고    scopus 로고
    • Randomised comparison of 5 years of adjuvant tamoxifen with continuous therapy for operable breast cancer. The Scottish Cancer Trials Breast Group
    • Stewart H.J., Forrest A.P., Everington D., McDonald C.C., Dewar J.A., Hawkins R.A., Prescott R.J., George W.D. Randomised comparison of 5 years of adjuvant tamoxifen with continuous therapy for operable breast cancer. The Scottish Cancer Trials Breast Group. Br. J. Cancer. 74:1996;297-299.
    • (1996) Br. J. Cancer , vol.74 , pp. 297-299
    • Stewart, H.J.1    Forrest, A.P.2    Everington, D.3    McDonald, C.C.4    Dewar, J.A.5    Hawkins, R.A.6    Prescott, R.J.7    George, W.D.8
  • 16
    • 0028000253 scopus 로고
    • Effects of tamoxifen on cardiovascular risk factors in postmenopausal women after 5 years of treatment
    • Love R.R., Wiebe D.A., Feyzi J.M., Newcomb P.A., Chappell R.J. Effects of tamoxifen on cardiovascular risk factors in postmenopausal women after 5 years of treatment. J. Natl. Cancer Inst. 86:1994;1534-1539.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1534-1539
    • Love, R.R.1    Wiebe, D.A.2    Feyzi, J.M.3    Newcomb, P.A.4    Chappell, R.J.5
  • 17
    • 0029904559 scopus 로고    scopus 로고
    • Tamoxifen - The long and short of it
    • Swain S.M. Tamoxifen - the long and short of it. J. Natl. Cancer Inst. 88:1996;1510-1512.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1510-1512
    • Swain, S.M.1
  • 18
    • 0028936687 scopus 로고
    • Tamoxifen and tumorigenicity: A predictable concern
    • Jordan V.C. Tamoxifen and tumorigenicity: a predictable concern. J. Natl. Cancer Inst. 87:1995;623-625.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 623-625
    • Jordan, V.C.1
  • 19
    • 0025068372 scopus 로고
    • Chemoprevention of mammary cancer by retinoids
    • Moon R.C., Mehta R.G. Chemoprevention of mammary cancer by retinoids. Basic Life Sci. 52:1990;213-224.
    • (1990) Basic Life Sci. , vol.52 , pp. 213-224
    • Moon, R.C.1    Mehta, R.G.2
  • 20
    • 0028206734 scopus 로고
    • Prospects of chemoprevention of human cancers with the synthetic retinoid fenretinide
    • Costa A., Formelli F., Chiesa F., Decensi A., De Palo G., Veronesi U. Prospects of chemoprevention of human cancers with the synthetic retinoid fenretinide. Cancer Res. 54:1994;2032s-2037s.
    • (1994) Cancer Res. , vol.54
    • Costa, A.1    Formelli, F.2    Chiesa, F.3    Decensi, A.4    De Palo, G.5    Veronesi, U.6
  • 21
    • 0026602830 scopus 로고
    • Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines
    • Kennedy M.J., Prestigiacomo L.J., Tyler G., May W.S., Davidson N.E. Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines. Cancer Res. 52:1992;1278-1283.
    • (1992) Cancer Res. , vol.52 , pp. 1278-1283
    • Kennedy, M.J.1    Prestigiacomo, L.J.2    Tyler, G.3    May, W.S.4    Davidson, N.E.5
  • 22
    • 0029118684 scopus 로고
    • Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds
    • Safe S. Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. Pharmacol. Ther. 67:1995;247-281.
    • (1995) Pharmacol. Ther. , vol.67 , pp. 247-281
    • Safe, S.1
  • 23
    • 0023475365 scopus 로고
    • Suppression of estrogen-regulated extracellular plasminogen activator activity of MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Lincoln D.W., Gillespie M.B., Seeger J.I., Martinez H.L., Dickerman H.W., Kumar S.A. Suppression of estrogen-regulated extracellular plasminogen activator activity of MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Res. 47:1987;6198-6203.
    • (1987) Cancer Res. , vol.47 , pp. 6198-6203
    • Gierthy, J.F.1    Lincoln, D.W.2    Gillespie, M.B.3    Seeger, J.I.4    Martinez, H.L.5    Dickerman, H.W.6    Kumar, S.A.7
  • 24
    • 0024232945 scopus 로고
    • Inhibition of postconfluent focus production in cultures of MCF-7 breast cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Lincoln D.W. Inhibition of postconfluent focus production in cultures of MCF-7 breast cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Breast Cancer Res. 12:1988;227-233.
    • (1988) Breast Cancer Res. , vol.12 , pp. 227-233
    • Gierthy, J.F.1    Lincoln, D.W.2
  • 25
    • 0025666708 scopus 로고
    • Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on cell growth and the secretion of the estrogen-induced 34-, 52- And 160-kDa proteins in human breast cancer cells
    • Biegel L., Safe S. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on cell growth and the secretion of the estrogen-induced 34-, 52- and 160-kDa proteins in human breast cancer cells. J. Steroid Biochem. Mol. Biol. 37:1990;725-732.
    • (1990) J. Steroid Biochem. Mol. Biol. , vol.37 , pp. 725-732
    • Biegel, L.1    Safe, S.2
  • 26
    • 0027093866 scopus 로고
    • Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells. Role of the Ah receptor
    • Chaloupka K., Krishnan V., Safe S. Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells. Role of the Ah receptor. Carcinogenesis. 13:1992;2223-2239.
    • (1992) Carcinogenesis , vol.13 , pp. 2223-2239
    • Chaloupka, K.1    Krishnan, V.2    Safe, S.3
  • 27
    • 0026747027 scopus 로고
    • Development of gel staining techniques for detecting the secretion of procathepsin D (52-kDa protein) in MCF-7 human breast cancer cells
    • Krishnan V., Narasimhan T.R., Safe S. Development of gel staining techniques for detecting the secretion of procathepsin D (52-kDa protein) in MCF-7 human breast cancer cells. Anal. Biochem. 204:1992;137-142.
    • (1992) Anal. Biochem. , vol.204 , pp. 137-142
    • Krishnan, V.1    Narasimhan, T.R.2    Safe, S.3
  • 28
    • 0027335891 scopus 로고
    • Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: Quantitative structure-activity relationships
    • Krishnan V., Safe S. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: quantitative structure-activity relationships. Toxicol. Appl. Pharmacol. 120:1993;55-61.
    • (1993) Toxicol. Appl. Pharmacol. , vol.120 , pp. 55-61
    • Krishnan, V.1    Safe, S.2
  • 29
    • 0028109671 scopus 로고
    • Indolo[3,2-b]carbazole: A dietary factor which exhibits both antiestrogenic and estrogenic activity
    • Liu H., Wormke M., Safe S., Bjeldanes L.F. Indolo[3,2-b]carbazole: a dietary factor which exhibits both antiestrogenic and estrogenic activity. J. Natl. Cancer Inst. 86:1994;1758-1765.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1758-1765
    • Liu, H.1    Wormke, M.2    Safe, S.3    Bjeldanes, L.F.4
  • 31
    • 0027494867 scopus 로고
    • Mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated decrease of the nuclear estrogen receptor in MCF-7 human breast cancer cells
    • Wang X., Porter W., Krishnan V., Narasimhan T.R., Safe S. Mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated decrease of the nuclear estrogen receptor in MCF-7 human breast cancer cells. Mol. Cell. Endocrinol. 96:1993;159-166.
    • (1993) Mol. Cell. Endocrinol. , vol.96 , pp. 159-166
    • Wang, X.1    Porter, W.2    Krishnan, V.3    Narasimhan, T.R.4    Safe, S.5
  • 32
    • 0025905989 scopus 로고
    • Evidence for a possible mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant Hepa 1c1c7 cells
    • Zacharewski T., Harris M., Safe S. Evidence for a possible mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant Hepa 1c1c7 cells. Biochem. Pharmacol. 41:1991;1931-1939.
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 1931-1939
    • Zacharewski, T.1    Harris, M.2    Safe, S.3
  • 33
    • 0028088840 scopus 로고
    • Selective responsiveness of breast cancer cells to indole-3-carbinol, a chemopreventative agent
    • Tiwari R.K., Guo L., Bradlow H.L., Telang N.T., Osborne M.P. Selective responsiveness of breast cancer cells to indole-3-carbinol, a chemopreventative agent. J. Natl. Cancer Inst. 86:1994;126-131.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 126-131
    • Tiwari, R.K.1    Guo, L.2    Bradlow, H.L.3    Telang, N.T.4    Osborne, M.P.5
  • 34
    • 0026691255 scopus 로고
    • 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: Evidence for the role of the Ah receptor
    • Zacharewski T., Harris M., Biegel L., Morrison V., Merchant M., Safe S. 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: evidence for the role of the Ah receptor. Toxicol. Appl. Pharmacol. 13:1992;311-318.
    • (1992) Toxicol. Appl. Pharmacol. , vol.13 , pp. 311-318
    • Zacharewski, T.1    Harris, M.2    Biegel, L.3    Morrison, V.4    Merchant, M.5    Safe, S.6
  • 35
    • 0030220312 scopus 로고    scopus 로고
    • Inhibition of prolactin receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 human breast cancer cells
    • Lu Y.-F., Sun G., Wang X., Safe S. Inhibition of prolactin receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 human breast cancer cells. Arch. Biochem. Biophys. 332:1996;35-40.
    • (1996) Arch. Biochem. Biophys. , vol.332 , pp. 35-40
    • Lu, Y.-F.1    Sun, G.2    Wang, X.3    Safe, S.4
  • 36
    • 0028122471 scopus 로고
    • Inhibition of estrogen-induced progesterone receptor in MCF-7 human breast cancer cells by aryl hydrocarbon (Ah) receptor agonists
    • Harper N., Wang X., Liu H., Safe S. Inhibition of estrogen-induced progesterone receptor in MCF-7 human breast cancer cells by aryl hydrocarbon (Ah) receptor agonists. Mol. Cell. Endocrinol. 104:1994;47-55.
    • (1994) Mol. Cell. Endocrinol. , vol.104 , pp. 47-55
    • Harper, N.1    Wang, X.2    Liu, H.3    Safe, S.4
  • 37
    • 0028285855 scopus 로고
    • Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17β-estradiol-induced pS2 expression
    • Zacharewski T., Bondy K., McDonell P., Wu Z.F. Antiestrogenic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on 17β-estradiol-induced pS2 expression. Cancer Res. 54:1994;2707-2713.
    • (1994) Cancer Res. , vol.54 , pp. 2707-2713
    • Zacharewski, T.1    Bondy, K.2    McDonell, P.3    Wu, Z.F.4
  • 39
    • 0028285283 scopus 로고
    • Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Holcomb M., Safe S. Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Lett. 82:1994;43-47.
    • (1994) Cancer Lett. , vol.82 , pp. 43-47
    • Holcomb, M.1    Safe, S.2
  • 40
    • 0027214018 scopus 로고
    • Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gierthy J.F., Bennett J.A., Bradley L.M., Cutler D.S. Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Res. 53:1993;3149-3153.
    • (1993) Cancer Res. , vol.53 , pp. 3149-3153
    • Gierthy, J.F.1    Bennett, J.A.2    Bradley, L.M.3    Cutler, D.S.4
  • 42
    • 0028884592 scopus 로고
    • Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells
    • Krishnan V., Porter W., Santostefano M., Wang X., Safe S. Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells. Mol. Cell. Biol. 15:1995;6710-6719.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6710-6719
    • Krishnan, V.1    Porter, W.2    Santostefano, M.3    Wang, X.4    Safe, S.5
  • 43
    • 0026756867 scopus 로고
    • MCDF, 6-methyl-1,3,8-trichlorodibenzofuran
    • Safe S. MCDF, 6-methyl-1,3,8-trichlorodibenzofuran. Drugs Future. 17:1992;564-565.
    • (1992) Drugs Future , vol.17 , pp. 564-565
    • Safe, S.1
  • 44
    • 0023839455 scopus 로고
    • 6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities
    • Astroff B., Zacharewski T., Safe S., Arlotto M.P., Parkinson A., Thomas P., Levin W. 6-Methyl-1,3,8-trichlorodibenzofuran as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: inhibition of the induction of rat cytochrome P-450 isozymes and related monooxygenase activities. Mol. Pharmacol. 33:1988;231-236.
    • (1988) Mol. Pharmacol. , vol.33 , pp. 231-236
    • Astroff, B.1    Zacharewski, T.2    Safe, S.3    Arlotto, M.P.4    Parkinson, A.5    Thomas, P.6    Levin, W.7
  • 45
    • 0024334491 scopus 로고
    • Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: Mechanistic studies
    • Harris M., Zacharewski T., Astroff B., Safe S. Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies. Mol. Pharmacol. 35:1989;729-735.
    • (1989) Mol. Pharmacol. , vol.35 , pp. 729-735
    • Harris, M.1    Zacharewski, T.2    Astroff, B.3    Safe, S.4
  • 46
    • 0024516732 scopus 로고
    • 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6 mice
    • Bannister R., Biegel L., Davis D., Astroff B., Safe S. 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6 mice. Toxicology. 54:1989;139-150.
    • (1989) Toxicology , vol.54 , pp. 139-150
    • Bannister, R.1    Biegel, L.2    Davis, D.3    Astroff, B.4    Safe, S.5
  • 47
    • 0024444243 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced porphyria in genetically inbred mice: Partial antagonism and mechanistic studies
    • Yao C., Safe S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced porphyria in genetically inbred mice: partial antagonism and mechanistic studies. Toxicol. Appl. Pharmacol. 100:1989;208-216.
    • (1989) Toxicol. Appl. Pharmacol. , vol.100 , pp. 208-216
    • Yao, C.1    Safe, S.2
  • 48
    • 0024307356 scopus 로고
    • 6-Substituted-1,3,8-trichlorodibenzofurans as 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists in the rat: Structure-activity relationships
    • Astroff B., Safe S. 6-Substituted-1,3,8-trichlorodibenzofurans as 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists in the rat: structure-activity relationships. Toxicology. 59:1989;285-296.
    • (1989) Toxicology , vol.59 , pp. 285-296
    • Astroff, B.1    Safe, S.2
  • 49
    • 0023816418 scopus 로고
    • Comparative antiestrogenic activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8-trichlorodibenzofuran in the female rat
    • Astroff B., Safe S. Comparative antiestrogenic activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8-trichlorodibenzofuran in the female rat. Toxicol. Appl. Pharmacol. 95:1988;435-443.
    • (1988) Toxicol. Appl. Pharmacol. , vol.95 , pp. 435-443
    • Astroff, B.1    Safe, S.2
  • 50
    • 0025946491 scopus 로고
    • 6-Alkyl-1,3,8-trichlorodibenzofurans as antiestrogens in female Sprague-Dawley rats
    • Astroff B., Safe S. 6-Alkyl-1,3,8-trichlorodibenzofurans as antiestrogens in female Sprague-Dawley rats. Toxicology. 69:1991;187-197.
    • (1991) Toxicology , vol.69 , pp. 187-197
    • Astroff, B.1    Safe, S.2
  • 51
    • 0030610471 scopus 로고    scopus 로고
    • Antiestrogenic activities of alternate substituted polychlorinated dibenzofurans in MCF-7 human breast cancer cells
    • in press
    • G. Sun, S. Safe, Antiestrogenic activities of alternate substituted polychlorinated dibenzofurans in MCF-7 human breast cancer cells. Cancer Chemother. Pharmacol. 1997, in press.
    • (1997) Cancer Chemother. Pharmacol.
    • Sun, G.1    Safe, S.2
  • 52
    • 0029598803 scopus 로고
    • Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: Structure-activity studies
    • Dickerson R., Howie-Keller L., Safe S. Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: structure-activity studies. Toxicol. Appl. Pharmacol. 135:1995;287-298.
    • (1995) Toxicol. Appl. Pharmacol. , vol.135 , pp. 287-298
    • Dickerson, R.1    Howie-Keller, L.2    Safe, S.3
  • 53
    • 0023617650 scopus 로고
    • Synthesis and aryl hydrocarbon receptor binding properties of radiolabeled polychlorinated dibenzofuran congeners
    • Farrell K., Safe L., Safe S. Synthesis and aryl hydrocarbon receptor binding properties of radiolabeled polychlorinated dibenzofuran congeners. Arch. Biochem. Biophys. 259:1987;185-195.
    • (1987) Arch. Biochem. Biophys. , vol.259 , pp. 185-195
    • Farrell, K.1    Safe, L.2    Safe, S.3
  • 54
    • 0000468691 scopus 로고
    • Mammary cancer induced by a single feeding of polynuclear hydrocarbons and its suppression
    • Huggins C., Grand L.C., Brillantes F.P. Mammary cancer induced by a single feeding of polynuclear hydrocarbons and its suppression. Nature. 189:1961;204-207.
    • (1961) Nature , vol.189 , pp. 204-207
    • Huggins, C.1    Grand, L.C.2    Brillantes, F.P.3
  • 55
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 56
    • 0029003424 scopus 로고
    • Production and characterization of monoclonal antibodies directed against the Ah receptor
    • Perdew G.H., Abbott B., Stanker L.H. Production and characterization of monoclonal antibodies directed against the Ah receptor. Hybridoma. 14:1995;279-283.
    • (1995) Hybridoma , vol.14 , pp. 279-283
    • Perdew, G.H.1    Abbott, B.2    Stanker, L.H.3
  • 57
    • 0019219257 scopus 로고
    • A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions
    • Pohl R.J., Fouts J.R. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Anal. Biochem. 107:1980;150-155.
    • (1980) Anal. Biochem. , vol.107 , pp. 150-155
    • Pohl, R.J.1    Fouts, J.R.2
  • 58
    • 0027859747 scopus 로고
    • Aromatase, its inhibitors and their use in breast cancer treatment
    • Brodie A.M. Aromatase, its inhibitors and their use in breast cancer treatment. Pharmacol. Ther. 60:1993;501-515.
    • (1993) Pharmacol. Ther. , vol.60 , pp. 501-515
    • Brodie, A.M.1
  • 59
    • 0018745418 scopus 로고
    • Aromatase inhibitors and their use in controlling oestrogen-dependent processes
    • Brodie A.M., Marsh D.A., Wu J.T., Brodie H.J. Aromatase inhibitors and their use in controlling oestrogen-dependent processes. J. Steroid Biochem. 11:1979;107-112.
    • (1979) J. Steroid Biochem. , vol.11 , pp. 107-112
    • Brodie, A.M.1    Marsh, D.A.2    Wu, J.T.3    Brodie, H.J.4
  • 60
    • 0018137952 scopus 로고
    • Inhibition of aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • Wattenburg L.W., Loub W.D. Inhibition of aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res. 38:1978;1410-1413.
    • (1978) Cancer Res. , vol.38 , pp. 1410-1413
    • Wattenburg, L.W.1    Loub, W.D.2
  • 62
    • 0028281779 scopus 로고
    • Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indol-3-carbinol
    • Kojima T., Tanaka T., Mori H. Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indol-3-carbinol. Cancer Res. 54:1994;1446-1449.
    • (1994) Cancer Res. , vol.54 , pp. 1446-1449
    • Kojima, T.1    Tanaka, T.2    Mori, H.3
  • 63
    • 0025140870 scopus 로고
    • Inhibitory effect of sinigrin and indole-3-carbinol in diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats
    • Tanaka T., Mori Y., Morishita Y., Hara A., Ohno T., Kojima T., Mori H. Inhibitory effect of sinigrin and indole-3-carbinol in diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats. Carcinogenesis. 11:1990;1403-1406.
    • (1990) Carcinogenesis , vol.11 , pp. 1403-1406
    • Tanaka, T.1    Mori, Y.2    Morishita, Y.3    Hara, A.4    Ohno, T.5    Kojima, T.6    Mori, H.7
  • 64
    • 0026785514 scopus 로고
    • Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis
    • Tanaka T., Kojima T., Morishita Y., Mori H. Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Jpn. J. Cancer Res. 83:1992;835-842.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 835-842
    • Tanaka, T.1    Kojima, T.2    Morishita, Y.3    Mori, H.4
  • 65
    • 0025174684 scopus 로고
    • The antiestrogenic effect of cigarette smoking in women
    • Baron J.A., La Vecchia C., Levi F. The antiestrogenic effect of cigarette smoking in women. Am. J. Obstet. Gynecol. 162:1990;502-514.
    • (1990) Am. J. Obstet. Gynecol. , vol.162 , pp. 502-514
    • Baron, J.A.1    La Vecchia, C.2    Levi, F.3
  • 67
    • 0029899032 scopus 로고    scopus 로고
    • Characterization of the molecular and structural properties of the transformed and nuclear aryl hydrocarbon (Ah) receptor complexes by proteolytic digestion
    • Santostefano M., Safe S. Characterization of the molecular and structural properties of the transformed and nuclear aryl hydrocarbon (Ah) receptor complexes by proteolytic digestion. Chem.-Biol. Interact. 100:1996;221-240.
    • (1996) Chem.-Biol. Interact. , vol.100 , pp. 221-240
    • Santostefano, M.1    Safe, S.2
  • 70
    • 0017078344 scopus 로고
    • Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata
    • Jordan V.C. Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata. Eur. J. Cancer. 12:1976;419-424.
    • (1976) Eur. J. Cancer , vol.12 , pp. 419-424
    • Jordan, V.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.