-
1
-
-
1942421701
-
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: The past, present and future
-
Ingelman-Sundberg M. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future. Trends Pharmacol Sci 2004; 25: 193-200.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 193-200
-
-
Ingelman-Sundberg, M.1
-
2
-
-
0742286803
-
-
Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2 D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol 2004; 369: 23-37.
-
Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2 D6: overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmacol 2004; 369: 23-37.
-
-
-
-
3
-
-
33847031732
-
CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure
-
Sistonen J, Sajantila A, Lao O, Corander J, Barbujani G, Fuselli S. CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet Genomics 2007; 17: 93-101.
-
(2007)
Pharmacogenet Genomics
, vol.17
, pp. 93-101
-
-
Sistonen, J.1
Sajantila, A.2
Lao, O.3
Corander, J.4
Barbujani, G.5
Fuselli, S.6
-
4
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 2002; 3: 229-243.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 229-243
-
-
Bradford, L.D.1
-
5
-
-
1642523162
-
Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
-
Marzolini C, Paus E, Buclin T, Kim RB. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther 2004; 75: 13-33.
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 13-33
-
-
Marzolini, C.1
Paus, E.2
Buclin, T.3
Kim, R.B.4
-
6
-
-
33749267293
-
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs
-
Cascorbi I. Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol Ther 2006; 112: 457-473.
-
(2006)
Pharmacol Ther
, vol.112
, pp. 457-473
-
-
Cascorbi, I.1
-
7
-
-
16544363963
-
Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
-
Ozawa S, Soyama A, Saeki M, Fukushima-Uesaka H, Itoda M, Koyano S, Sai K, Ohno Y, Saito Y, Sawada J. Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1. Drug Metab Pharmacokinet 2004; 19: 83-95.
-
(2004)
Drug Metab Pharmacokinet
, vol.19
, pp. 83-95
-
-
Ozawa, S.1
Soyama, A.2
Saeki, M.3
Fukushima-Uesaka, H.4
Itoda, M.5
Koyano, S.6
Sai, K.7
Ohno, Y.8
Saito, Y.9
Sawada, J.10
-
8
-
-
32044455207
-
MDR1 genotype-related pharmacokinetics: Fact or fiction?
-
Sakaeda T. MDR1 genotype-related pharmacokinetics: fact or fiction? Drug Metab Pharmacokinet 2005; 20: 391-414.
-
(2005)
Drug Metab Pharmacokinet
, vol.20
, pp. 391-414
-
-
Sakaeda, T.1
-
9
-
-
34548089635
-
Pharmacogenetically relevant polymorphisms in Portugal
-
Oliveira E, Marsh S, van Booven DJ, Amorim A, Prata MJ, McLeod HL. Pharmacogenetically relevant polymorphisms in Portugal. Pharmacogenomics 2007; 8: 703-712.
-
(2007)
Pharmacogenomics
, vol.8
, pp. 703-712
-
-
Oliveira, E.1
Marsh, S.2
van Booven, D.J.3
Amorim, A.4
Prata, M.J.5
McLeod, H.L.6
-
10
-
-
0033871198
-
Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR
-
Hersberger M, Marti-Jaun J, Rentsch K, Hanseler E. Rapid detection of the CYP2D6*3, CYP2D6*4, and CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR. Clin Chem 2000; 46: 1072-1077.
-
(2000)
Clin Chem
, vol.46
, pp. 1072-1077
-
-
Hersberger, M.1
Marti-Jaun, J.2
Rentsch, K.3
Hanseler, E.4
-
11
-
-
0033590590
-
Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes
-
Lundqvist E, Johansson I, Ingelman-Sundberg M. Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes. Gene 1999; 226: 327-338.
-
(1999)
Gene
, vol.226
, pp. 327-338
-
-
Lundqvist, E.1
Johansson, I.2
Ingelman-Sundberg, M.3
-
12
-
-
0034017850
-
GOLD - graphical overview of linkage disequilibrium
-
Abecassis GR, Cookson WO. GOLD - graphical overview of linkage disequilibrium. Bioinformatics 2000; 16: 182-183.
-
(2000)
Bioinformatics
, vol.16
, pp. 182-183
-
-
Abecassis, G.R.1
Cookson, W.O.2
-
13
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001; 68: 978-989.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
-
14
-
-
0036204756
-
Molecular genetics of CYP2 D6: Clinical relevance with focus on psychotropic drugs
-
Bertilsson L, Dahl ML, Dalen P, Al-Shurbaji A. Molecular genetics of CYP2 D6: clinical relevance with focus on psychotropic drugs. Br J Clin Pharmacol 2002; 53: 111-122.
-
(2002)
Br J Clin Pharmacol
, vol.53
, pp. 111-122
-
-
Bertilsson, L.1
Dahl, M.L.2
Dalen, P.3
Al-Shurbaji, A.4
-
15
-
-
13544249943
-
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
-
Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J 2005; 5: 6-13.
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 6-13
-
-
Ingelman-Sundberg, M.1
-
16
-
-
0030432585
-
Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles
-
Aklillu E, Persson I, Bertilsson L, Johansson I, Rodrigues F, Ingelman-Sundberg M. Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. J Pharmacol Exp Ther 1996; 278: 441-446.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 441-446
-
-
Aklillu, E.1
Persson, I.2
Bertilsson, L.3
Johansson, I.4
Rodrigues, F.5
Ingelman-Sundberg, M.6
-
17
-
-
0030811291
-
Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians
-
McLellan RA, Oscarson M, Seidegard J, Evans DA, Ingelman-Sundberg M. Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians. Pharmacogenetics 1997; 7: 187-191.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 187-191
-
-
McLellan, R.A.1
Oscarson, M.2
Seidegard, J.3
Evans, D.A.4
Ingelman-Sundberg, M.5
-
18
-
-
0035051412
-
MDR1 pharmacogenetics: Frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity
-
Ameyaw MM, Regateiro F, Li T, Liu X, Tariq M, Mobarek A, Thornton N, Folayan GO, Githang'a J, Indalo A, Ofori-Adjei D, Price-Evans DA, McLeod HL. MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity. Pharmacogenetics 2001; 11: 217-221.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 217-221
-
-
Ameyaw, M.M.1
Regateiro, F.2
Li, T.3
Liu, X.4
Tariq, M.5
Mobarek, A.6
Thornton, N.7
Folayan, G.O.8
Githang'a, J.9
Indalo, A.10
Ofori-Adjei, D.11
Price-Evans, D.A.12
McLeod, H.L.13
-
20
-
-
0037307357
-
Frequency distribution of C3435T mutation in exon 26 of the MDR1 gene in a Spanish population
-
Bernal ML, Sinues B, Fanlo A, Mayayo E. Frequency distribution of C3435T mutation in exon 26 of the MDR1 gene in a Spanish population. Ther Drug Monit 2003; 25: 107-111.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 107-111
-
-
Bernal, M.L.1
Sinues, B.2
Fanlo, A.3
Mayayo, E.4
-
21
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, Taylor A, Xie HG, McKinsey J, Zhou S, Lan LB, Schuetz JD, Schuetz EG,Wilkinson GR. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70: 189-199.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
Taylor, A.7
Xie, H.G.8
McKinsey, J.9
Zhou, S.10
Lan, L.B.11
Schuetz, J.D.12
Schuetz, E.G.13
Wilkinson, G.R.14
-
22
-
-
10744222684
-
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
-
Kroetz DL, Pauli-Magnus C, Hodges LM, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Carlson EJ, Herskowitz I, Giacomini KM, Clark AG. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics 2003; 13: 481-494.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 481-494
-
-
Kroetz, D.L.1
Pauli-Magnus, C.2
Hodges, L.M.3
Huang, C.C.4
Kawamoto, M.5
Johns, S.J.6
Stryke, D.7
Ferrin, T.E.8
DeYoung, J.9
Taylor, T.10
Carlson, E.J.11
Herskowitz, I.12
Giacomini, K.M.13
Clark, A.G.14
-
23
-
-
42149157159
-
Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs
-
Hung CC, Chen CC, Lin CJ, Liou HH. Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugs. Pharmacogenet Genomics 2008; 18: 390-402.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 390-402
-
-
Hung, C.C.1
Chen, C.C.2
Lin, C.J.3
Liou, H.H.4
-
24
-
-
33749989048
-
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells
-
Salama NN, Yang Z, Bui T, Ho RJ. MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells. J Pharm Sci 2006; 95: 2293-2308.
-
(2006)
J Pharm Sci
, vol.95
, pp. 2293-2308
-
-
Salama, N.N.1
Yang, Z.2
Bui, T.3
Ho, R.J.4
-
25
-
-
33748624897
-
Characterization of variant alleles of cytochrome CYP2D6 in a Spanish population
-
Menoyo A, del Rio E, Baiget M. Characterization of variant alleles of cytochrome CYP2D6 in a Spanish population. Cell Biochem Funct 2006; 24: 381-385.
-
(2006)
Cell Biochem Funct
, vol.24
, pp. 381-385
-
-
Menoyo, A.1
del Rio, E.2
Baiget, M.3
-
26
-
-
2942568145
-
Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population
-
Scordo MG, Caputi AP, D'Arrigo C, Fava G, Spina E. Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population. Pharmacol Res 2004; 50: 195-200.
-
(2004)
Pharmacol Res
, vol.50
, pp. 195-200
-
-
Scordo, M.G.1
Caputi, A.P.2
D'Arrigo, C.3
Fava, G.4
Spina, E.5
-
27
-
-
34447269513
-
Genetic polymorphisms of drug-metabolizing enzymes CYP2D6, CYP2C9, CYP2C19 and CYP3A5 in the Greek population
-
Arvanitidis K, Ragia G, Iordanidou M, Kyriaki S, Xanthi A, Tavridou A, Manolopoulos VG. Genetic polymorphisms of drug-metabolizing enzymes CYP2D6, CYP2C9, CYP2C19 and CYP3A5 in the Greek population. Fundam Clin Pharmacol 2007; 21: 419-426.
-
(2007)
Fundam Clin Pharmacol
, vol.21
, pp. 419-426
-
-
Arvanitidis, K.1
Ragia, G.2
Iordanidou, M.3
Kyriaki, S.4
Xanthi, A.5
Tavridou, A.6
Manolopoulos, V.G.7
-
28
-
-
0032772078
-
Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population
-
Aynacioglu AS, Sachse C, Bozkurt A, Kortunay S, Nacak M, Schroder T, Kayaalp SO, Roots I, Brockmoller J. Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population. Clin Pharmacol Ther 1999; 66: 185-192.
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 185-192
-
-
Aynacioglu, A.S.1
Sachse, C.2
Bozkurt, A.3
Kortunay, S.4
Nacak, M.5
Schroder, T.6
Kayaalp, S.O.7
Roots, I.8
Brockmoller, J.9
-
29
-
-
0042888963
-
Genetic polymorphisms of cytochromes P450: CYP2C9, CYP2C19, and CYP2D6 in Croatian population
-
Bozina N, Granic P, Lalic Z, Tramisak I, Lovric M, Stavljenic-Rukavina A. Genetic polymorphisms of cytochromes P450: CYP2C9, CYP2C19, and CYP2D6 in Croatian population. Croat Med J 2003; 44: 425-428.
-
(2003)
Croat Med J
, vol.44
, pp. 425-428
-
-
Bozina, N.1
Granic, P.2
Lalic, Z.3
Tramisak, I.4
Lovric, M.5
Stavljenic-Rukavina, A.6
-
30
-
-
0031038038
-
Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
-
Sachse C, Brockmoller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet 1997; 60: 284-295.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 284-295
-
-
Sachse, C.1
Brockmoller, J.2
Bauer, S.3
Roots, I.4
-
31
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A, Cascorbi I, Gerloff T, Roots I, Eichelbaum M, Brinkmann U. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97: 3473-3478.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
Brinkmann, U.11
-
32
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Schaeffeler E, Eichelbaum M, Brinkmann U, Roots I. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001; 69: 169-174.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
Meisel, C.4
Hoffmeyer, S.5
Schwab, M.6
Schaeffeler, E.7
Eichelbaum, M.8
Brinkmann, U.9
Roots, I.10
-
33
-
-
34447515970
-
Determination of ABCB1 polymorphisms and haplotypes frequencies in a French population
-
Jeannesson E, Albertini L, Siest G, Gomes AM, Ribeiro V, Aslanidis C, Schmitz G, Visvikis-Siest S. Determination of ABCB1 polymorphisms and haplotypes frequencies in a French population. Fundam Clin Pharmacol 2007; 21: 411-418.
-
(2007)
Fundam Clin Pharmacol
, vol.21
, pp. 411-418
-
-
Jeannesson, E.1
Albertini, L.2
Siest, G.3
Gomes, A.M.4
Ribeiro, V.5
Aslanidis, C.6
Schmitz, G.7
Visvikis-Siest, S.8
-
35
-
-
56749150856
-
Genotype and allele frequencies of MDR1 gene C1236T polymorphism in a Turkish population
-
Gumus-Akay G, Rustemoglu A, Karadag A, Sunguroglu A. Genotype and allele frequencies of MDR1 gene C1236T polymorphism in a Turkish population. Genet Mol Res 2008; 7: 1193-1199.
-
(2008)
Genet Mol Res
, vol.7
, pp. 1193-1199
-
-
Gumus-Akay, G.1
Rustemoglu, A.2
Karadag, A.3
Sunguroglu, A.4
-
36
-
-
1942421704
-
Genomic evidence for recent positive selection at the human MDR1 gene locus
-
Tang K, Wong LP, Lee EJ, Chong SS, Lee CG. Genomic evidence for recent positive selection at the human MDR1 gene locus. Hum Mol Genet 2004; 13: 783-797.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 783-797
-
-
Tang, K.1
Wong, L.P.2
Lee, E.J.3
Chong, S.S.4
Lee, C.G.5
-
37
-
-
7944236606
-
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition
-
Yi SY, Hong KS, Lim HS, Chung JY, Oh DS, Kim JR, Jung HR, Cho JY, Yu KS, Jang IJ, Shin SG. A variant 2677A allele of the MDR1 gene affects fexofenadine disposition. Clin Pharmacol Ther 2004; 76: 418-427.
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 418-427
-
-
Yi, S.Y.1
Hong, K.S.2
Lim, H.S.3
Chung, J.Y.4
Oh, D.S.5
Kim, J.R.6
Jung, H.R.7
Cho, J.Y.8
Yu, K.S.9
Jang, I.J.10
Shin, S.G.11
-
38
-
-
34447560176
-
Genetic polymorphism of cytochrome P450s and P-glycoprotein in the Finnish population
-
Hilli J, Rane A, Lundgren S, Bertilsson L, Laine K. Genetic polymorphism of cytochrome P450s and P-glycoprotein in the Finnish population. Fundam Clin Pharmacol 2007; 21: 379-386.
-
(2007)
Fundam Clin Pharmacol
, vol.21
, pp. 379-386
-
-
Hilli, J.1
Rane, A.2
Lundgren, S.3
Bertilsson, L.4
Laine, K.5
-
39
-
-
0036400925
-
Distribution of allelic variants of functional C3435T polymorphism of drug transporter MDR1 gene in a sample of Polish population
-
Jamroziak K, Balcerczak E, Mlynarski W, Mirowski M, Robak T. Distribution of allelic variants of functional C3435T polymorphism of drug transporter MDR1 gene in a sample of Polish population. Pol J Pharmacol 2002; 54: 495-500.
-
(2002)
Pol J Pharmacol
, vol.54
, pp. 495-500
-
-
Jamroziak, K.1
Balcerczak, E.2
Mlynarski, W.3
Mirowski, M.4
Robak, T.5
-
40
-
-
0041410075
-
Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population
-
Gaikovitch EA, Cascorbi I, Mrozikiewicz PM, Brockmoller J, Frotschl R, Kopke K, Gerloff T, Chernov JN, Roots I. Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population. Eur J Clin Pharmacol 2003; 59: 303-312.
-
(2003)
Eur J Clin Pharmacol
, vol.59
, pp. 303-312
-
-
Gaikovitch, E.A.1
Cascorbi, I.2
Mrozikiewicz, P.M.3
Brockmoller, J.4
Frotschl, R.5
Kopke, K.6
Gerloff, T.7
Chernov, J.N.8
Roots, I.9
|