Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion

Journal of Nutritional Biochemistry

Volumn 17, Issue 4, 2006, Pages 234-241

  Cao, Dehua ^a   Zhou, Chen ^a   Sun, Liping ^a   Xue, Renhao ^a   Xu, Jun ^a   Liu, Zhili ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Arachidonic acid; Eicosanoid productions; Ethyl docosahexaenoate; Gerbil; Transient forebrain ischemia

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; DRUG VEHICLE; ETHYL DOCOSAHEXAENOATE; ICOSANOID; LEUKOTRIENE B4; LEUKOTRIENE C4; PROSTAGLANDIN F2 ALPHA; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; ATTENUATION; BRAIN BLOOD FLOW; BRAIN EDEMA; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FATTY ACID SYNTHESIS; FOREBRAIN; GERBIL; ICOSANOID METABOLISM; LIPID BRAIN LEVEL; LIPID COMPOSITION; MALE; NONHUMAN; REPERFUSION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; ARACHIDONIC ACID; BRAIN; BRAIN CHEMISTRY; BRAIN EDEMA; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; DINOPROST; DOCOSAHEXAENOIC ACIDS; EICOSANOIDS; FATTY ACIDS; GERBILLINAE; LEUKOTRIENE B4; LEUKOTRIENE C4; LIPIDS; MALE; REPERFUSION; THROMBOXANE B2;

ANIMALIA; GERBILLINAE;

EID: 33645078417     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2005.04.006     Document Type: Article

References (43)

1. A.A. Farooqui, and L.A. Horrocks Excitatory amino acid receptors, neuronal membrane phospholipid metabolism and neurological disorders Brain Res Rev 16 1991 171 191
2. M. Kubota, M. Nakane, K. Narita, T. Nakagomi, A. Tamura, and H. Hisaki Mild hypothermia reduces the rate of metabolism of arachidonic acid following postischemic reperfusion Brain Res 779 1998 297 300
3. S. Yoshida, M. Ikeda, R. Busto, M. Santiso, E. Martinez, and M. Ginsberg Cerebral phosphoinositide, triacylglycerol and energy metabolism in reversible ischemia: origin and fate of free fatty acids J Neurochem 47 1986 744 757
4. B.K. Siesjö, K. Katsura, Q. Zhao, S. Felbergrova, K. Pahlmark, and P. Siesjö Mechanisms of secondary brain damage in global and focal ischemia: a speculative synthesis J Neurotrauma 12 1995 943 956
5. +-ATPase activity in global cerebral ischemia-exposed rats Prog Neuro-Psychopharmacol Biol Psychiatry 26 2002 1319 1326
6. R.J. Gaudet, I. Alam, and L. Levine Accumulation of cyclooxygenase products of arachidonic acid metabolism in gerbil brain during reperfusion after bilateral common carotid occlusion J Neurochem 35 1980 653 658
7. K.K. Bhakoo, H.A. Crockard, P.C. Lascelles, and S.F. Avery Prostaglandin synthesis and oedema formation during reperfusion following experimented brain ischemia in the gerbil Stroke 15 1984 891 895
8. B.C. White, J.M. Sullivan, D.J. Degracia, B.J. O'Neil, R.W. Neumar, and L.I. Grossman Brain ischemia and reperfusion: molecular mechanisms of neuronal injury J Neurol Sci 179 2000 S1 S33
9. R.J. Dempsey, M.W. Roy, K. Meyer, D.E. Cowen, and H.H. Tai Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia J Neurosurg 64 1986 118 124
10. S.T. Chen, C.Y. Hsu, E.L. Hogan, P.V. Halushka, O.I. Linet, and F.M. Yatsu Thromboxane, prostacyclin and leukotrienes in cerebral ischemia Neurology 36 1986 466 470
11. 2 and indomethacin prevent impairment of post-ischemic brain reperfusion in the dog Stroke 10 1979 629 637
12. D.H. Nugteren Arachidonate lipoxygenase in blood platelets Biochim Biophys Acta 380 1975 299 307
13. H. Mabe, H. Nagai, and T. Suzuka Role of brain tissue leukotriene in brain oedema following cerebral ischemia: effects of a 5-lipoxygenase inhibitor AA-861 Neurol Res 12 1990 165 169
14. N. Salem Jr., H.Y. Kim, and J.A. Yergey Docosahexaenoic acid: membrane function and metabolism A.P. Simopoulos R.R. Kifer R.E. Martin Health effects of polyunsaturated fatty acids in seafoods 1986 Academic Press Orlando (FL) 263 317
15. K. Umemura, Y. Toshima, F. Asai, and M. Nakashima Effect of dietary docosahexaenoic acid in the rat middle artery thrombosis model Thromb Res 78 1995 379 387
16. M. Okada, T. Amamoto, M. Tomonaga, A. Kawachi, K. Yazawa, and K. Mine The chronic administration of docosahexaenoic acid reduces the spatial cognitive deficit following transient forebrain ischemia in rats Neuroscience 71 1996 17 25
17. H.E. Krokan, K.S. Bjerve, and A. Mork The central bioavailability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro Biochim Biophys Acta 1168 1993 59 67
18. D.H. Cao, J.F. Xu, R.H. Xue, W.F. Zheng, and Z.L. Liu Protective effect of chronic ethyl docosahexaenoate administration on brain injury in ischemic gerbils Pharmacol Biochem Behav 79 2004 651 659
19. S. Gamoh, M. Hashimoto, K. Sugioka, M.S. Hossain, N. Hata, and Y. Misawa Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats Neuroscience 93 1999 237 241
20. E.G. Bligh, and W.J. Dyer A rapid method of total lipid extraction and purification Can J Biochem Physiol 37 1959 911 917
21. S. Glozman, P. Green, and E. Yavin Intraamniotic ethyl docosahexaenoate administration protects fetal rat brain from ischemic stress J Neurochem 70 1998 2484 2491
22. H. Minamisawa, P. Mellergård, M.L. Smith, F. Bengtsson, S. Theander, and F.B. Möller Preservation of brain temperature during ischemia in rats Stroke 21 1990 758 764
23. E. Pasztor, L. Symon, N.W.C. Dorsch, and N.M. Branston The hydrogen clearance method in assessment of blood flow in cortex, white matter and deep nuclei of baboons Stroke 4 1973 556 567
24. P.K. Andrus, B.M. Taylor, F.F. Sun, and E.D. Hall Effects of the lipid peroxidation inhibitor tirilazad mesylate (U-74006F) on gerbil brain eicosanoid levels following ischemia and reperfusion Brain Res 659 1994 126 132
25. G. Calapia, F. Squadrito, A. Rizzo, M.C. Marciano, G.M. Campo, and A.P. Caputi Multiple actions of the coumarin derivative cloricromene and its protective effects on ischemic brain injury Naunyn-Schmiedeberg's Arch Pharmacol 351 1995 209 215
26. S. Rehancrona, E. Westerberge, B. Åkesson, and B.K. Siesjö Brain cortical fatty acid and phospholipids during and following complete and severe incomplete ischemia J Neurochem 38 1982 84 93
27. T. Nakagomi, T. Sasoki, T. Kirino, A. Tamura, M. Noguchi, and I. Saito Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus Stroke 20 1989 925 929
28. Y. Takeuchi, H. Morii, M. Tamura, O. Hayaishi, and Y. Watanabe A possible mechanism of mitochondrial dysfunction during cerebral ischemia: inhibition of mitochondrial respiration activity by arachidonic acid Arch Biochem Biophys 289 1991 33 38
29. T. Koide, O. Gotoh, T. Asano, and K. Takakura Alteration of the eicosanoid synthetic capacity of the rat brain microvessels following ischemia: relevance to ischemic brain edema J Neurochem 44 1985 85 93
30. O. Kempski, E. Shohami, D. Von Lubitz, J.M. Hallenbeck, and G. Feuerstein Postischemic production of eicosanoids in gerbil brain Stroke 18 1987 111 119
31. P.M. Patel, J.C. Drummond, D.J. Cole, and T.L. Yaksh Differential temperature sensitivity of ischemia-induced glutamate release and eicosanoid production in rats Brain Res 650 1994 205 211
32. 2 and C on free fatty acid release during complete ischemia in rat neocortex J Neurosurg 76 1992 648 651
33. K. Abe, K. Kogure, H. Yamamoto, M. Imazawa, and K. Miyamoto Mechanism of arachidonic acid liberation during ischemia in gerbil cortex J Neurochem 48 1987 503 509
34. W.S. Fenton, J. Hibbeln, and M. Knable Essential fatty acids, lipid membrane abnormalities and the diagnosis and treatment of schizophrenia Biol Psychiatry 47 2000 8 21
35. M. Shikano, Y. Masuzawa, and K. Yazawa Effect of docosahexaenoic acid on the generation of platelet-activating factor by eosinophilic leukemia cells, Eol-1 J Immunol 15 1993 3525 3533
36. 2 activity in the neurites/nerve growth cones of PC12 cells J Neurosci Res 54 1998 805 813
37. J.A. Nettleton ω-3 Fatty acids: comparison of plant and seafood sources in human nutrition J Am Diet Assoc 91 1991 331 337
38. C. von Schacky, S. Fisher, and P.C. Weber Long-term effects of dietary marine omega-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans J Clin Invest 76 1985 1626 1631
39. R.C. Osburne, and J.H. Halsey Cerebral blood flow: a predictor of recovery from ischemia in the gerbil Arch Neurol 32 1975 457 461
40. V.L. Marcheselli, S. Hong, W.J. Lukiw, X.H. Tian, K. Gronert, and A. Musto Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression J Biol Chem 278 2003 43807 43817
41. C.N. Serhan Novel ω-3-derived local mediators in anti-inflammation and resolution Pharmacol Ther 105 2005 7 21
42. M.E. Hemler, and W.E.M. Lands Evidence for a peroxide initiated free radical mechanism of prostaglandin biosynthesis J Biol Chem 255 1980 6253 6261
43. W.E.M. Lands Interactions of lipid hydroperoxides with eicosanoid biosynthesis Free Radic Biol Med 1 1985 97 101