Induction of apoptosis by tea polyphenols mediated through mitochondrial cell death pathway in mouse skin tumors

Cancer Biology and Therapy

Volumn 8, Issue 13, 2009, Pages 1281-1287

  Roy, Preeti ^a   Nigam, Nidhi ^a   George, Jasmine ^a   Srivastava, Smita ^a   Shukla, Yogeshwer ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Apoptosis; BTP; Chemoprevention; DMBA; GTP; Mouse skin tumorigenesis

Indexed keywords

BLACK TEA EXTRACT; CASPASE; CYTOCHROME C; DIMETHYLBENZ[A]ANTHRACENE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYPHENOL DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SURVIVIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CELL DEATH; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVATION; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SKIN CANCER; SKIN CARCINOGENESIS; TEA; UPREGULATION;

EID: 68149164681     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.13.8728     Document Type: Article

References (44)

1. Chen C, King A. Dietary cancer-chemopreventive compounds: from signaling and gene expression to pharmacological. Trends Mol Med 2005; 26:318-28.
2. Yang CS, Maliakal P, Meng X. Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 2002; 42:25-54.
3. Graham HN. Green tea composition, consumption and polyphenol chemistry. Prev Med 1992; 21:334-50.
4. Cabrera C, Gimenez R, Lopez MC. Determination of tea components with antioxidant activity. J Agric Food Chem 2003; 51:4427-35.
5. Yang CS, Ju J, Lu G, Xiao H, Hao X, Sang S, Lambert JD. Cancer prevention by tea and tea polyphenols. Asia Pac J Clin Nutr 2008; 17:245-8.
6. Rodgers AE, Hafer LJ, Iskander YS, Yang S. Black tea and mammary gland carcinogenesis by 7,12-dimethylbenz (a) anthracene rats fed control of high fat diets. Carcinogenesis 1998; 19:1269-73.
7. Hu G, Han C, Chen J. Inhibition of oncogene expression by green tea and (-)epigallcatechin gallate in mice. Nut Cancer 1995; 24:203-9.
8. Sevin A, Oztas P, Senen D, Han U, Karaman C, Tarimci N, et al. Effects of polyphenols on skin damage due to ultraviolet A rays: an experimental study on rats. J Eur Acad Dermatol Venereol 2007; 21:650-6.
9. Weisburger JH. Tea and health: the underlying mechanisms. Proc Soc Exp Biol Med 1999; 220:271-5.
10. Camouse MM, Hanneman KK, Conrad EP, Baron ED. Protective effects of tea polyphenols and caffeine. Expert Rev Anticancer Ther 2005; 5:1061-8.
11. Conney AH, Wang ZY, Huang MT, Ho CT, Yang CS. Inhibitory effect of green tea on tumorigenesis by chemicals and ultraviolet. Prev Med 1992; 3:361-9.
12. Wang ZY, Huang MT, Ho CT, Chang R, Ma W, Ferraro T, et al. Inhibitory effect of green tea on the growth of established skin papilomas in mice. Cancer Res 1992; 52:6657-65.
13. Javed S, Mehrotra NK, Shukla Y. Chemopreventive effects of black tea polyphenols in mouse skin model of carcinogenesis. Biomed Environ Sci 1998; 4:307-13.
14. Martin KR. Targeting apoptosis with dietary bioactive agents. Exp Biol Med 2006; 231:117-29.
15. Siddiqui IA, Adhami VM, Afaq F, Ahmad N, Mukhtar H. Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase-pathways by tea polyphenols in human prostate cancer cells. J Cell Biochem 2004; 91:232-42.
16. Johnson D, Lardy H. Methods in Enzymology, Oxidation and Phosphorylation. In: Estabrook RW, Pullman ME, ed. Vol X, New York: Academic Press 1967; 94-6.
17. Arora A, Siddiqui A, Shukla Y. Modulation of p53 in 7,12-dimethylbenz[a] anthraceneinduced skin tumors by diallyl sulfide in Swiss albino mice. Mol Cancer Ther 2004; 3:1459-66.
18. Lowry OH, Rosenbrough NK, Farr AL. Protein measurement with folin phenol reagent. J Biol Chem 1951; 193:265-75.
19. Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain M, Lane D, Hall PA. The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res 1994; 54:614-7.
20. Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer drugs Cell 1993; 74:957-67.
21. Clarke AR, Gledhill S, Hooper ML, Bird CC, Wyllie AH. p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation. Oncogene 1994; 9:1767-73.
22. McCarthy SA, Symonds HS, Van-Dyke T. Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53. Proc Natl Acad Sci USA 1994; 91:3979-83.
23. Cory S, Adams J. Killing cancer cells by flipping the Bcl-2/Bax switch. Cancer Cell 2005; 8:5-6.
24. Hantz H, Young L, Martin K. Physiologically attainable concentrations of lycopene induce mitochondrial apoptosis in LNCaP human prostate cancer cells. Exp Biol Med 2005; 230:171-9.
25. Chai J, Du C, Wu JW, Kyin S, Wang X, Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 2000; 406:855-62.
26. Mc Michael AJ. Food, nutrition, physical activity and cancer prevention. Authoritative report from World Cancer Research Fund provides global update. Public Health Nutr 2008; 11:762-3.
27. Landis-Piwowar KR, Kuhn DJ, Wan SB, Chen D, Chan TH, Dou QP. Evaluation of proteasome-inhibitory and apoptosis-inducing potencies of novel (-)-EGCG analogs and their prodrugs. Int J Mol Med 2005; 15:735-42.
28. Sanaha H, Kelloff G, Steele V, Rao C, Reddy B. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res 1997; 57:1301-5.
29. Yang K, Lamprecht S, Liu Y, Shinozaki H, Fan K, Leung D. Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. Carcinogenesis 2000; 21:1655-60.
30. Reddy B, Wang C, Samaha H, Lubet R, Steele V, Kelloff G. Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. Cancer Res 1997; 57:420-5.
31. Khan N, Adhami VM, Mukhtar H. Apoptosis by dietary agents for prevention and treatment of cancer. Biochem Pharmacol 2008; 76:1333-9.
32. Lambert J, Hong J, Yang G, Liao J, Yang C. Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations. Am J Clin Nutr 2005; 81:284-91.
33. Amundson SA, Myers TG, Fornace AJ. Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress. Oncogene 1998; 17:3287-99.
34. Levine A. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323-31.
35. Fuster JJ, Sanz-González SM, Moll UM, Andrés V. Classic and novel roles of p53: prospects for anticancer therapy. Trends Mol Med 2007; 13:192-9.
36. Mowat MR. p53 in tumor progression: life, death and everything. Adv Cancer Res 1998; 74:25-48.
37. Korsmeyer SJ, Yin XM, Oltvai ZN, Veis-Novack DJ, Linette GP. Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family. Biochim Biophys Acta 1995; 1271:63-6.
38. Nomura M, Shimizu S, Ito T, Narita M, Matsuda H, Tsujimoto Y. Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2. Cancer Res 1999; 59:5542-8.
39. Murphy KM, Ranganathan V, Farnsworth ML, Kavallaris M, Lock RB. Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ 2000; 7:102-11.
40. Thornberry NA. Caspases: key mediators of apoptosis. Chem Biol 1998; 5:97-103.
41. Radovic N, Cucic S, Altarac S. Molecular aspects of apoptosis. Acta Med Croatica 2008; 62:249-56.
42. Altieri DC. Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 2003; 22:8581-9.
43. Deveraux QL, Reed JC. IAP family proteins - suppressors of apoptosis. Genes Dev 1999; 13:239-52.
44. Castedo M, Perfettini JL, Roumier T, Andreau K, Medema R, Kroemer G. Cell death by mitotic catastrophe: a molecular definition. Oncogene 2004; 23:2825-37.