Ergothioneine rescues PC12 cells from β-amyloid-induced apoptotic death

Free Radical Biology and Medicine

Volumn 36, Issue 3, 2004, Pages 288-299

  Jang, Jung Hee ^a   Aruoma, Okezie I ^b   Jen, Ling Sun ^b   Chung, Hae Young ^c   Surh, Young Joon ^a  

^a Seoul National University   (South Korea)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c Pusan National University   (South Korea)

Author keywords

Alzheimer's disease; Apoptosis; Ergothioneine; Free radicals; Oxidative and or nitrosative stress; Peroxynitrite; Amyloid

Indexed keywords

AMYLOID BETA PROTEIN; CASPASE 3; CHLORIDE; LINSIDOMINE; NITROPRUSSIDE SODIUM; PEPTIDE; PEROXYNITRITE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME DEGRADATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NEUROTOXICITY; NITRATION; NITROSATION; NONHUMAN; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT;

MAMMALIA;

EID: 1642440245     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2003.11.005     Document Type: Article

References (42)

1. Selkoe D.J. Amyloid beta-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271:1996;487-498.
2. Quinn J., Davis F., Woodward W.R., Eckenstein F. β-Amyloid plaques induce neuritic dystrophy of nitric oxide-producing neurons in a transgenic mouse model of Alzheimer's disease. Exp. Neurol. 168:2001;203-212.
3. Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemens J., Donaldson T., Gillespie F. Alzheimer-type neuropathy in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature. 373:1995;523-527.
4. Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Aβ elevation and amyloid plaques in transgenic mice. Science. 274:1996;99-103.
5. Jen L.S., Hart A.J., Jen A., Relvas J.B., Gentleman S.M., Garey L.J., Patel A. Alzheimer's peptide kills cells of retina in vivo. Nature. 392:1998;140-141.
6. Harkany T., Abraham I., Timmerman W., Laskey G., Toth B., Sasvar M., Kanya C., Sebens J.B., Korf J., Nyakas C., Zarandi M., Seos K., Penke B., Luiten P.G. β-Amyloid neurotoxicity is mediated by glutamate triggered excitotoxic cascade in rat nucleus basalis. Eur. J. Neurosci. 12:2000;2735-2745.
7. Yuan J., Yanker B.A. Apoptosis in the nervous system. Nature. 407:2000;802-809.
8. Butterfield D.A., Drake J., Pocermich C., Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β-peptide. Trends Mol. Med. 7:2001;548-554.
9. Mattson M.P. Impairment of membrane transport and signal transduction systems by amyloidogenic proteins. Methods Enzymol. 309:1999;733-746.
10. Law A., Gauthier S., Quirion R. Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity. Br. J. Pharmacol. 133:2001;1114-1124.
11. Troy C.M., Rabacchi S.A., Friedman W.J., Frappier T.F., Brown K., Shelanski M.L. Caspase-2 mediates neuronal cell death induced by beta-amyloid. J. Neurosci. 20:2000;1386-1392.
12. Chabrier P.E., Demerle-Pallardy C., Auguet M. Nitric oxide synthases: targets for therapeutic strategies in neurological diseases. Cell. Mol. Life Sci. 55:1999;1029-1035.
13. Law A., Gauthier S., Quirion R. Say NO to Alzheimer's disease: the putative links between nitric oxide and dementia of the Alzheimer's type. Brain Res. Brain Res. Rev. 35:2001;73-96.
14. Smith M.A., Richey Harris P.L., Sayre L.M., Beckman J.S., Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. 17:1997;2253-2657.
15. Melville D.B., Horner W.H., Otken C.C., Ludwig M.L. Studies of the origin of ergothioneine in animals. J. Biol. Chem. 213:1955;61-68.
16. Kaneko I., Takeuci Y., Yamoka Y., Tanaka Y., Fukuda T., Fukumori Y., Mayumi T., Hama T. Quantitative determination of ergothioneine in plasma and tissues by TLC-dosimetry. Chem. Pharm. Bull. 28:1980;3093-3097.
17. Mitsuyama H., May J.M. Uptake and antioxidant effects of ergothioneine in human erythrocytes. Clin. Sci. 97:1999;407-411.
18. Van den Broeke L.T., Beyersbergen van Henegouwen G.M. Thiols as potential UV radiation protectors: an in vitro study. J. Photochem. Photobiol. Biol. 17:1993;279-286.
19. Motohashi N., Mori I. Thiol-induced hydroxyl radical formation and scavenger effect of thiocarbamides on hydroxyl radicals. J. Inorg. Biochem. 26:1986;205-212.
20. Akanmu D., Cecchini R., Aruoma O.I., Halliwell B. The antioxidant action of ergothioneine. Arch. Biochem. Biophys. 288:1991;10-16.
21. Asmus K.-D., Bensasson R.V., Bernier J.-L., Houssin R., Land E.J. One electron oxidation of ergothioneine and analogues investigated by pulse radiolysis: redox reactions involving ergothioneine and vitamin C. Biochem. J. 315:1996;625-629.
22. Aruoma O.I., Whiteman M.E., Halliwell B. The antioxidant action of ergothioneine: assessment of its ability to scavenge peroxynitrite. Biochem. Biophys. Res. Commun. 231:1997;389-391.
23. Aruoma O.I., Spencer J.P.E., Mahmood N. Protection against oxidative damage and cell death by natural antioxidant ergothioneine. Food Chem. Toxicol. 37:1999;1043-1053.
24. Moncaster J.A., Walsh D.T., Gentleman S.M., Jen L.-S., Aruoma O.I. Ergothioneine treatment protects neurons against N-methyl-D-aspartate excitotoxicity: in an in vivo retinal model. Neurosci. Lett. 328:2002;55-59.
25. Guijarro M.V., Indart A., Aruoma O.I., Viana M., Bonet B. Effects of ergothioneine on diabetic embryopathy in pregnant rats. Food Chem. Toxicol. 40:2002;1751-1755.
26. Jang J.-H., Surh Y.-J. Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radic. Biol. Med. 34:2003;1100-1110.
27. Loeffler M., Kroemer G. The mitochondrion in cell death control: certainties and incognita. Exp. Cell Res. 256:2000;19-26.
28. Korsmeyer S.J., Shutter J.R., Veis D.J., Merry D.E., Oltvai Z.N. Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Semin. Cancer Biol. 4:1993;327-332.
29. Miranda S., Opazo C., Larrondo L.F., Munoz F.J., Ruiz F., Leighton F., Inestrosa N.C. The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease. Prog. Neurobiol. 62:2000;633-648.
30. Behl C. Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches. Prog. Neurobiol. 57:1999;301-323.
31. Radi R., Peluffo G., Alvarez M.N., Naviliat M., Cayota A. Unraveling peroxynitrite formation in biological systems. Free Radic. Biol. Med. 30:2001;463-488.
32. Good P.F., Wermer P., Hsu A., Olanow C.W., Perl D.P. Evidence for neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol. 149:1996;21-28.
33. Orth M., Schapira A.H.V. Mitochondrial involvement in Parkinson's disease. Neurochem. Int. 40:2002;533-541.
34. Olney J.W. Excitotoxicity, apoptosis and neuropsychiatric disorders. Curr. Opin. Pharmacol. 3:2002;1-9.
35. Sian J., Dexter D.T., Daniel S.E., Lees A.J., Agid Y., Javoy-Agid F., Jenner P., Marsden C.D. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting the basal ganglia. Ann. Neurol. 36:1994;348-355.
36. Dyrks T., Dyrks E., Hartmann T., Masters C., Beyreuther K. Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation. J. Biol. Chem. 267:1992;18210-18217.
37. Schubert D., Chevion M. The role of iron in beta amyloid toxicity. Biochem. Biophys. Res. Commun. 216:1995;702-707.
38. Pappolla M.A., Sos M., Omar R.A., Bick R.J., Hickson-Bick D.L., Reiter R.J., Efthimiopoulos S., Robakis N.K. Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. J. Neurosci. 17:1997;1683-1690.
39. Qin L., Liu Y., Cooper C., Liu B., Wilson B., Hong J.S. Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species. J. Neurochem. 83:2002;973-983.
40. Lee M., Hyun D.H., Marshall K.A., Ellerby L.M., Bredesen D.E., Jenner P., Halliwell B. Effect of overexpression of BCL-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome. Free Radic. Biol. Med. 31:2001;1550-1559.
41. Sandoval M., Zhang X.J., Liu X., Mannick E.E., Clark D.A., Miller M.J. Peroxynitrite-induced apoptosis in T84 and RAW 264.7 cells: attenuation by L-ascorbic acid. Free Radic. Biol. Med. 22:1997;489-495.
42. Spear N., Estevez A.G., Johnson G.V., Bredesen D.E., Thompson J.A., Beckman J.S. Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2. Arch. Biochem. Biophys. 356:1998;41-45.