Gene profiles of THP-1 macrophages after in vitro exposure to respiratory (non-)sensitizing chemicals: Identification of discriminating genetic markers and pathway analysis

Toxicology in Vitro

Volumn 23, Issue 6, 2009, Pages 1151-1162

  Verstraelen, Sandra ^a   Nelissen, Inge ^a   Hooyberghs, Jef ^a   Witters, Hilda ^a   Schoeters, Greet ^a,b   Van Cauwenberge, Paul ^c   Van Den Heuvel, Rosette ^a  

^a FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

Markers; Pathway analysis; PDGF signaling; Respiratory sensitization; THP 1 macrophages; Transcriptomics

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ACROLEIN; ALLERGEN; HEXAMETHYLENE DIISOCYANATE; INITIATION FACTOR 4E; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SEMAPHORIN; SEMAPHORIN 7A; TRIMELLITIC ANHYDRIDE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 36L2;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN GENOME; IMMUNE RESPONSE; MACROPHAGE; MARKER GENE; NUCLEOTIDE SEQUENCE; RESPIRATORY TRACT ALLERGY; SENSITIZATION; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS;

ALLERGENS; CELL LINE; DISCRIMINANT ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; IRRITANTS; MACROPHAGES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PILOT PROJECTS; PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 68049101193     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.06.007     Document Type: Article

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