Activation and inactivation of the iron hormone hepcidin: Biochemical characterization of prohepcidin cleavage and sequential degradation to N-terminally truncated hepcidin isoforms

Blood Cells, Molecules, and Diseases

Volumn 43, Issue 2, 2009, Pages 169-179

  Schranz, Melanie ^a   Bakry, Rania ^b   Creus, Marc ^c   Bonn, Günther ^b   Vogel, Wolfgang ^a   Zoller, Heinz ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Hemochromatosis; Hepcidin; Iron; Proprotein convertases

Indexed keywords

FURIN; HEPCIDIN; HORMONE PRECURSOR; PEPTIDASE; PROHEPCIDIN; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE 3; PROPROTEIN CONVERTASE 5; PROPROTEIN CONVERTASE 6; PROPROTEIN CONVERTASE 7; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HORMONE RELEASE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; HUMANS; MICE; PEPTIDE HYDROLASES; PEPTIDES; PROPROTEIN CONVERTASES; PROTEIN ISOFORMS; PROTEIN PRECURSORS; RECOMBINANT FUSION PROTEINS;

EID: 68049083806     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2009.03.008     Document Type: Article

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