Pro-hepcidin is unable to degrade the iron exporter ferroportin unless maturated by a furin-dependent process

Journal of Hepatology

Volumn 50, Issue 2, 2009, Pages 394-401

  Gagliardo, Bruno ^a   Kubat, Nicole ^b,c   Faye, Audrey ^b,c   Jaouen, Maryse ^a   Durel, Béatrice ^b,c   Deschemin, Jean Christophe ^b,c   Canonne Hergaux, François ^d   Sari, Marie Agnès ^a   Vaulont, Sophie ^b,c  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSTITUT COCHIN   (France)

^c INSERM   (France)

^d INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

Author keywords

Furin; Hepcidin; Hormone; Iron; Macrophages

Indexed keywords

FERROPORTIN; FURIN; HEPCIDIN; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; WILD TYPE;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CATION TRANSPORT PROTEINS; CELL LINE; FURIN; MACROPHAGES; MICE; PROTEIN PRECURSORS;

EID: 58149308295     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2008.09.018     Document Type: Article

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