-
1
-
-
0032503962
-
Regulation of CFTR ion channel gating by MgATP
-
Aleksandrov, A.A., and J.R. Riordan. 1998. Regulation of CFTR ion channel gating by MgATP. FEBS Lett. 431:97-101.
-
(1998)
FEBS Lett
, vol.431
, pp. 97-101
-
-
Aleksandrov, A.A.1
Riordan, J.R.2
-
2
-
-
0033759953
-
The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating
-
Aleksandrov, A.A., X. Chang, L. Aleksandrov, and J.R. Riordan. 2000. The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating. J. Physiol. 528:259-265.
-
(2000)
J. Physiol
, vol.528
, pp. 259-265
-
-
Aleksandrov, A.A.1
Chang, X.2
Aleksandrov, L.3
Riordan, J.R.4
-
4
-
-
67649659825
-
Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator
-
Aleksandrov, A.A., L. Cui, and J.R. Riordan. 2009. Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator. J. Physiol. 587:2875-2886.
-
(2009)
J. Physiol
, vol.587
, pp. 2875-2886
-
-
Aleksandrov, A.A.1
Cui, L.2
Riordan, J.R.3
-
5
-
-
13444274310
-
Gating of acetylcholine receptor channels: Brownian motion across a broad transition state
-
Auerbach, A. 2005. Gating of acetylcholine receptor channels: brownian motion across a broad transition state. Proc. Natl. Acad. Sci. USA. 102:1408-1412.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1408-1412
-
-
Auerbach, A.1
-
6
-
-
36549084005
-
How to turn the reaction coordinate into time
-
Auerbach, A. 2007. How to turn the reaction coordinate into time. J. Gen. Physiol. 130:543-546.
-
(2007)
J. Gen. Physiol
, vol.130
, pp. 543-546
-
-
Auerbach, A.1
-
7
-
-
11844258265
-
A speed limit for conformational change of an allosteric membrane protein
-
Chakrapani, S., and A. Auerbach. 2005. A speed limit for conformational change of an allosteric membrane protein. Proc. Natl. Acad. Sci. USA. 102:87-92.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 87-92
-
-
Chakrapani, S.1
Auerbach, A.2
-
8
-
-
1842686239
-
Gating dynamics of the acetylcholine receptor extracellular domain
-
Chakrapani, S., T.D. Bailey, and A. Auerbach. 2004. Gating dynamics of the acetylcholine receptor extracellular domain. J. Gen. Physiol. 123:341-356.
-
(2004)
J. Gen. Physiol
, vol.123
, pp. 341-356
-
-
Chakrapani, S.1
Bailey, T.D.2
Auerbach, A.3
-
9
-
-
42049096734
-
CLC-0 and CFTR: Chloride channels evolved from transporters
-
Chen, T.Y., and T.C. Hwang. 2008. CLC-0 and CFTR: chloride channels evolved from transporters. Physiol. Rev. 88:351-387.
-
(2008)
Physiol. Rev
, vol.88
, pp. 351-387
-
-
Chen, T.Y.1
Hwang, T.C.2
-
10
-
-
0029745419
-
Nonequilibrium gating and voltage dependence of the ClC-0 Cl- channel
-
Chen, T.Y., and C. Miller. 1996. Nonequilibrium gating and voltage dependence of the ClC-0 Cl- channel. J. Gen. Physiol. 108:237-250.
-
(1996)
J. Gen. Physiol
, vol.108
, pp. 237-250
-
-
Chen, T.Y.1
Miller, C.2
-
11
-
-
0242415285
-
Electrostatic control and chloride regulation of the fast gating of ClC-0 chloride channels
-
Chen, T.Y., M.F. Chen, and C.W. Lin. 2003. Electrostatic control and chloride regulation of the fast gating of ClC-0 chloride channels. J. Gen. Physiol. 122:641-651.
-
(2003)
J. Gen. Physiol
, vol.122
, pp. 641-651
-
-
Chen, T.Y.1
Chen, M.F.2
Lin, C.W.3
-
12
-
-
53249130652
-
The twain shall meet: Channels, transporters and things between. Meeting on Membrane Transport in Flux: the Ambiguous Interface Between Channels and Pumps
-
9:960-965
-
Csanády, L., and J.A. Mindell. 2008. The twain shall meet: channels, transporters and things between. Meeting on Membrane Transport in Flux: the Ambiguous Interface Between Channels and Pumps. EMBO Rep. 9:960-965.
-
(2008)
EMBO Rep
-
-
Csanády, L.1
Mindell, J.A.2
-
13
-
-
33750499982
-
Thermodynamics of CFTR channel gating: A spreading conformational change initiates an irreversible gating cycle
-
Csanády, L., A.C. Nairn, and D.C. Gadsby. 2006. Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle. J. Gen. Physiol. 128: 523-533.
-
(2006)
J. Gen. Physiol
, vol.128
, pp. 523-533
-
-
Csanády, L.1
Nairn, A.C.2
Gadsby, D.C.3
-
14
-
-
0037197654
-
Structure of the transition state of gating in the acetylcholine receptor channel pore: A phi-value analysis
-
Cymes, G.D., C. Grosman, and A. Auerbach. 2002. Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis. Biochemistry. 41:5548-5555.
-
(2002)
Biochemistry
, vol.41
, pp. 5548-5555
-
-
Cymes, G.D.1
Grosman, C.2
Auerbach, A.3
-
15
-
-
67349185408
-
Ion channels versus ion pumps: The principal difference, in principle
-
Gadsby, D.C. 2009. Ion channels versus ion pumps: the principal difference, in principle. Nat. Rev. Mol. Cell Biol. 10:344-352.
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 344-352
-
-
Gadsby, D.C.1
-
16
-
-
33645307384
-
The ABC protein turned chloride channel whose failure causes cystic fibrosis
-
Gadsby, D.C., P. Vergani, and L. Csanády. 2006. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature. 440:477-483.
-
(2006)
Nature
, vol.440
, pp. 477-483
-
-
Gadsby, D.C.1
Vergani, P.2
Csanády, L.3
-
17
-
-
0034677524
-
Mapping the conformational wave of acetylcholine receptor channel gating
-
Grosman, C., M. Zhou, and A. Auerbach. 2000. Mapping the conformational wave of acetylcholine receptor channel gating. Nature. 403:773-776.
-
(2000)
Nature
, vol.403
, pp. 773-776
-
-
Grosman, C.1
Zhou, M.2
Auerbach, A.3
-
18
-
-
0001060616
-
Structure-energy relations, reaction mechanism, and disparity of progress of concerted reaction events
-
Grunwald, E. 1985. Structure-energy relations, reaction mechanism, and disparity of progress of concerted reaction events. J. Am. Chem. Soc. 107:125-133.
-
(1985)
J. Am. Chem. Soc
, vol.107
, pp. 125-133
-
-
Grunwald, E.1
-
19
-
-
0028070453
-
Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating
-
Gunderson, K.L., and R.R. Kopito. 1994. Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating. J. Biol. Chem. 269:19349-19353.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 19349-19353
-
-
Gunderson, K.L.1
Kopito, R.R.2
-
20
-
-
0029117303
-
Conformational states of CFTR associated with channel gating: The role ATP binding and hydrolysis
-
Gunderson, K.L., and R.R. Kopito. 1995. Conformational states of CFTR associated with channel gating: the role ATP binding and hydrolysis. Cell. 82:231-239.
-
(1995)
Cell
, vol.82
, pp. 231-239
-
-
Gunderson, K.L.1
Kopito, R.R.2
-
21
-
-
0035019469
-
ABC transporters: Physiology, structure and mechanism-an overview
-
Higgins, C.F. 2001. ABC transporters: physiology, structure and mechanism-an overview. Res. Microbiol. 152:205-210.
-
(2001)
Res. Microbiol
, vol.152
, pp. 205-210
-
-
Higgins, C.F.1
-
22
-
-
65749102092
-
Gating of the CFTR Clchannel by ATP-driven nucleotide-binding domain dimerisation
-
Hwang, T.C., and D.N. Sheppard. 2009. Gating of the CFTR Clchannel by ATP-driven nucleotide-binding domain dimerisation. J. Physiol. 587:2151-2161.
-
(2009)
J. Physiol
, vol.587
, pp. 2151-2161
-
-
Hwang, T.C.1
Sheppard, D.N.2
-
23
-
-
0028340159
-
Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis
-
Hwang, T.C., G. Nagel, A.C. Nairn, and D.C. Gadsby. 1994. Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. Proc. Natl. Acad. Sci. USA. 91:4698-4702.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4698-4702
-
-
Hwang, T.C.1
Nagel, G.2
Nairn, A.C.3
Gadsby, D.C.4
-
24
-
-
0030668944
-
Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis
-
Ishihara, H., and M.J. Welsh. 1997. Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis. Am. J. Physiol. 273:C1278-C1289.
-
(1997)
Am. J. Physiol
, vol.273
-
-
Ishihara, H.1
Welsh, M.J.2
-
25
-
-
0038711772
-
-
Janas, E., M. Hofacker, M. Chen, S. Gompf, C. van der Does, and R. Tampé. 2003. The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p. J. Biol. Chem. 278:26862-26869.
-
Janas, E., M. Hofacker, M. Chen, S. Gompf, C. van der Does, and R. Tampé. 2003. The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p. J. Biol. Chem. 278:26862-26869.
-
-
-
-
26
-
-
49449090405
-
The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporter
-
Lísal, J., and M. Maduke. 2008. The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporter. Nat. Struct. Mol. Biol. 15:805-810.
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 805-810
-
-
Lísal, J.1
Maduke, M.2
-
27
-
-
33947306589
-
Theoretical relations among rate constants, barriers, and Brønsted slopes of chemical reactions
-
Marcus, R.A. 1968. Theoretical relations among rate constants, barriers, and Brønsted slopes of chemical reactions. J. Phys. Chem. 72:891-899.
-
(1968)
J. Phys. Chem
, vol.72
, pp. 891-899
-
-
Marcus, R.A.1
-
28
-
-
33645296826
-
ClC chloride channels viewed through a transporter lens
-
Miller, C. 2006. ClC chloride channels viewed through a transporter lens. Nature. 440:484-489.
-
(2006)
Nature
, vol.440
, pp. 484-489
-
-
Miller, C.1
-
29
-
-
27744443715
-
Plasticity of acetylcholine receptor gating motions via rate-energy relationships
-
Mitra, A., R. Tascione, A. Auerbach, and S. Licht. 2005. Plasticity of acetylcholine receptor gating motions via rate-energy relationships. Biophys. J. 89:3071-3078.
-
(2005)
Biophys. J
, vol.89
, pp. 3071-3078
-
-
Mitra, A.1
Tascione, R.2
Auerbach, A.3
Licht, S.4
-
30
-
-
0037077296
-
Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters
-
Moody, J.E., L. Millen, D. Binns, J.F. Hunt, and P.J. Thomas. 2002. Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. J. Biol. Chem. 277:21111-21114.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 21111-21114
-
-
Moody, J.E.1
Millen, L.2
Binns, D.3
Hunt, J.F.4
Thomas, P.J.5
-
32
-
-
0028924935
-
Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion
-
Pusch, M., U. Ludewig, A. Rehfeldt, and T.J. Jentsch. 1995. Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion. Nature. 373:527-531.
-
(1995)
Nature
, vol.373
, pp. 527-531
-
-
Pusch, M.1
Ludewig, U.2
Rehfeldt, A.3
Jentsch, T.J.4
-
33
-
-
0025270712
-
Steady-state coupling of ionchannel conformations to a transmembrane ion gradient
-
Richard, E.A., and C. Miller. 1990. Steady-state coupling of ionchannel conformations to a transmembrane ion gradient. Science. 247:1208-1210.
-
(1990)
Science
, vol.247
, pp. 1208-1210
-
-
Richard, E.A.1
Miller, C.2
-
34
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan, J.R., J.M. Rommens, B. Kerem, N. Alon, R. Rozmahel, Z. Grzelczak, J. Zielenski, S. Lok, N. Plavsic, J.L. Chou, et al. 1989. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 245:1066-1073.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
-
35
-
-
36048936399
-
Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR
-
Scott-Ward, T.S., Z. Cai, E.S. Dawson, A. Doherty, A.C. Da Paula, H. Davidson, D.J. Porteous, B.J. Wainwright, M.D. Amaral, D.N. Sheppard, and A.C. Boyd. 2007. Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR. Proc. Natl. Acad. Sci. USA. 104:16365-16370.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16365-16370
-
-
Scott-Ward, T.S.1
Cai, Z.2
Dawson, E.S.3
Doherty, A.4
Da Paula, A.C.5
Davidson, H.6
Porteous, D.J.7
Wainwright, B.J.8
Amaral, M.D.9
Sheppard, D.N.10
Boyd, A.C.11
-
36
-
-
0036342413
-
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer
-
Smith, P.C., N. Karpowich, L. Millen, J.E. Moody, J. Rosen, P.J. Thomas, and J.F. Hunt. 2002. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol. Cell. 10:139-149.
-
(2002)
Mol. Cell
, vol.10
, pp. 139-149
-
-
Smith, P.C.1
Karpowich, N.2
Millen, L.3
Moody, J.E.4
Rosen, J.5
Thomas, P.J.6
Hunt, J.F.7
-
37
-
-
0242321011
-
Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus
-
Verdon, G., S.V. Albers, N. van Oosterwijk, B.W. Dijkstra, A.J. Driessen, and A.M. Thunnissen. 2003. Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus. J. Mol. Biol. 334:255-267.
-
(2003)
J. Mol. Biol
, vol.334
, pp. 255-267
-
-
Verdon, G.1
Albers, S.V.2
van Oosterwijk, N.3
Dijkstra, B.W.4
Driessen, A.J.5
Thunnissen, A.M.6
-
38
-
-
14544300522
-
CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains
-
Vergani, P., S.W. Lockless, A.C. Nairn, and D.C. Gadsby. 2005. CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains. Nature. 433:876-880.
-
(2005)
Nature
, vol.433
, pp. 876-880
-
-
Vergani, P.1
Lockless, S.W.2
Nairn, A.C.3
Gadsby, D.C.4
-
39
-
-
0032954806
-
Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme
-
Zeltwanger, S., F. Wang, G.T. Wang, K.D. Gillis, and T.C. Hwang. 1999. Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme. J. Gen. Physiol. 113:541-554.
-
(1999)
J. Gen. Physiol
, vol.113
, pp. 541-554
-
-
Zeltwanger, S.1
Wang, F.2
Wang, G.T.3
Gillis, K.D.4
Hwang, T.C.5
-
40
-
-
27744499937
-
Phi-value analysis of a linear, sequential reaction mechanism: Theory and application to ion channel gating
-
Zhou, Y., J.E. Pearson, and A. Auerbach. 2005. Phi-value analysis of a linear, sequential reaction mechanism: theory and application to ion channel gating. Biophys. J. 89:3680-3685.
-
(2005)
Biophys. J
, vol.89
, pp. 3680-3685
-
-
Zhou, Y.1
Pearson, J.E.2
Auerbach, A.3
|