메뉴 건너뛰기




Volumn 48, Issue 29, 2009, Pages 6794-6804

Charge conduction properties of a parallel-stranded DNA G-quadruplex: Implications for chromosomal oxidative damage

Author keywords

[No Author keywords available]

Indexed keywords

CHARGE CONDUCTION; CHARGE FLOW; CONDUCTION PROPERTIES; DAMAGE PATTERNS; DNA DUPLEXES; DNA-BASED BIOSENSORS; DUPLEX DNA; ELECTRON HOLE; ELECTRONIC FACTORS; EUKARYOTIC CHROMOSOMES; FLOW PROPERTIES; G-QUADRUPLEX; G-QUADRUPLEX STRUCTURE; G-QUADRUPLEXES; IN-VIVO; OXIDATIVE DAMAGE; QUADRUPLEXES; STERIC CROWDING; TELOMERES;

EID: 67651238587     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9007484     Document Type: Article
Times cited : (34)

References (53)
  • 1
    • 0030978765 scopus 로고    scopus 로고
    • The DNA structures at the ends of eukaryotic chromosomes
    • Wellinger, R., and Sen, D. (1997) The DNA structures at the ends of eukaryotic chromosomes. Eur. J. Cancer 33, 735-749.
    • (1997) Eur. J. Cancer , vol.33 , pp. 735-749
    • Wellinger, R.1    Sen, D.2
  • 2
    • 38449106276 scopus 로고    scopus 로고
    • Discovery of alternative DNA structures: A heroic decade (1979-1989)
    • Mirkin, S. M. (2008) Discovery of alternative DNA structures: a heroic decade (1979-1989). Front. Biosci. 13, 1064-1071.
    • (2008) Front. Biosci , vol.13 , pp. 1064-1071
    • Mirkin, S.M.1
  • 3
    • 0015515155 scopus 로고
    • Origin of concatemeric T7 DNA
    • Watson, J. D. (1972) Origin of concatemeric T7 DNA. Nat. New. Biol. 239, 197-201.
    • (1972) Nat. New. Biol , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 4
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider, C. W., and Blackburn, E. H. (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43, 405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 5
    • 0030990291 scopus 로고    scopus 로고
    • Molecular model for telomeric heterochromatin in yeast
    • Grunstein, M. (1997) Molecular model for telomeric heterochromatin in yeast. Curr. Opin. Cell Biol. 9, 383-387.
    • (1997) Curr. Opin. Cell Biol , vol.9 , pp. 383-387
    • Grunstein, M.1
  • 6
    • 35648985643 scopus 로고    scopus 로고
    • Aging and cancer: Killing two birds with one worm
    • Brunet, A. (2007) Aging and cancer: killing two birds with one worm. Nat. Genet. 39, 1306-1307.
    • (2007) Nat. Genet , vol.39 , pp. 1306-1307
    • Brunet, A.1
  • 7
    • 0023788886 scopus 로고
    • Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis
    • Sen, D., and Gilbert, W. (1988) Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis. Nature 334, 364-366.
    • (1988) Nature , vol.334 , pp. 364-366
    • Sen, D.1    Gilbert, W.2
  • 8
    • 0024787884 scopus 로고
    • Monovalent cation-induced structure of telomeric DNA: The G-quartet model
    • Williamson, J. R., Raghuraman, M. K., and Cech, T. R. (1989) Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell 59, 871-880.
    • (1989) Cell , vol.59 , pp. 871-880
    • Williamson, J.R.1    Raghuraman, M.K.2    Cech, T.R.3
  • 9
    • 0024843757 scopus 로고
    • Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops
    • Sundquist, W. I., and Klug, A. (1989) Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops. Nature 342, 825-829.
    • (1989) Nature , vol.342 , pp. 825-829
    • Sundquist, W.I.1    Klug, A.2
  • 10
    • 0025269255 scopus 로고
    • A sodium-potassium switch in the formation of four-stranded G4-DNA
    • Sen, D., and Gilbert, W. (1990) A sodium-potassium switch in the formation of four-stranded G4-DNA. Nature 344, 410-414.
    • (1990) Nature , vol.344 , pp. 410-414
    • Sen, D.1    Gilbert, W.2
  • 11
    • 0026500052 scopus 로고
    • Novel DNA superstructures formed by telomere-like oligomers
    • Sen, D., and Gilbert, W. (1992) Novel DNA superstructures formed by telomere-like oligomers. Biochemistry 31, 65-70.
    • (1992) Biochemistry , vol.31 , pp. 65-70
    • Sen, D.1    Gilbert, W.2
  • 12
    • 0033079847 scopus 로고    scopus 로고
    • Long-range oxidative damage to DNA: Effects of distance and sequence
    • Nunez, M., Hall, D. B., and Barton, J. K. (1999) Long-range oxidative damage to DNA: effects of distance and sequence. Chem. Biol. 6, 85-97.
    • (1999) Chem. Biol , vol.6 , pp. 85-97
    • Nunez, M.1    Hall, D.B.2    Barton, J.K.3
  • 13
    • 0035969706 scopus 로고    scopus 로고
    • On the non-uniform distribution of guanine in introns of human genes: Possible protection of exons against oxidation by proximal intron poly-G sequences
    • Friedman, K. A., and Heller, A. (2001) On the non-uniform distribution of guanine in introns of human genes: possible protection of exons against oxidation by proximal intron poly-G sequences. J. Phys. Chem. B 105, 11858-11865.
    • (2001) J. Phys. Chem. B , vol.105 , pp. 11858-11865
    • Friedman, K.A.1    Heller, A.2
  • 14
    • 0034566154 scopus 로고    scopus 로고
    • On the hypothesis of cathodic protection of genes
    • Heller, A. (2000) On the hypothesis of cathodic protection of genes. Faraday Discuss. 116, 1-13.
    • (2000) Faraday Discuss , vol.116 , pp. 1-13
    • Heller, A.1
  • 15
    • 1542366714 scopus 로고    scopus 로고
    • Guanosine distribution and oxidation resistance in eight eukaryotic genomes
    • Friedman, K. A., and Heller, A. (2004) Guanosine distribution and oxidation resistance in eight eukaryotic genomes. J. Am. Chem. Soc. 126, 2368-2371.
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 2368-2371
    • Friedman, K.A.1    Heller, A.2
  • 16
    • 37049065201 scopus 로고
    • The semiconductivity of organic substances, Part 9 - nucleic acid in the dry state
    • Eley, D. D., and Spivey, D. I. (1962) The semiconductivity of organic substances, Part 9 - nucleic acid in the dry state. Trans. Faraday Soc. 58, 411-415.
    • (1962) Trans. Faraday Soc , vol.58 , pp. 411-415
    • Eley, D.D.1    Spivey, D.I.2
  • 17
    • 0031946478 scopus 로고    scopus 로고
    • Paradigms, supermolecules, electron transfer and chemistry at a distance. What's the problem? The science or the paradigm?
    • Turro, N., and Barton, J. K. (1998) Paradigms, supermolecules, electron transfer and chemistry at a distance. What's the problem? The science or the paradigm?. J. Biol. Inorg. Chem. 3, 201-209.
    • (1998) J. Biol. Inorg. Chem , vol.3 , pp. 201-209
    • Turro, N.1    Barton, J.K.2
  • 18
    • 0035997345 scopus 로고    scopus 로고
    • Electron transfer in DNA
    • Giese, B. (2002) Electron transfer in DNA. Annu. Rev. Biochem. 71, 51-70.
    • (2002) Annu. Rev. Biochem , vol.71 , pp. 51-70
    • Giese, B.1
  • 19
    • 0034058321 scopus 로고    scopus 로고
    • Long-range charge transfer in DNA: Transient structural distortions control the distance dependence
    • Schuster, G. B. (2000) Long-range charge transfer in DNA: transient structural distortions control the distance dependence. Acc. Chem. Res. 33, 253-260.
    • (2000) Acc. Chem. Res , vol.33 , pp. 253-260
    • Schuster, G.B.1
  • 20
    • 0033587765 scopus 로고    scopus 로고
    • Long-distance charge transport in duplex DNA: The phonon-assisted polaron-like hopping mechanism
    • Henderson, P. T., Jones, D., Hampikian, G., Kan, Y., and Schuster, G. B. (1999) Long-distance charge transport in duplex DNA: the phonon-assisted polaron-like hopping mechanism. Proc. Natl. Acad. Sci. U.S.A. 96, 8353-8358.
    • (1999) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 8353-8358
    • Henderson, P.T.1    Jones, D.2    Hampikian, G.3    Kan, Y.4    Schuster, G.B.5
  • 21
    • 21344445906 scopus 로고    scopus 로고
    • Long-range radical cation migration in DNA: Investigation of the mechanism
    • Joy, A., and Schuster, G. B. (2005) Long-range radical cation migration in DNA: investigation of the mechanism. Chem. Commun. 22, 2778-2784.
    • (2005) Chem. Commun , vol.22 , pp. 2778-2784
    • Joy, A.1    Schuster, G.B.2
  • 23
    • 0033545293 scopus 로고    scopus 로고
    • Electronic motion in DNA
    • Ratner, M. (1999) Electronic motion in DNA. Nature 397, 480-481.
    • (1999) Nature , vol.397 , pp. 480-481
    • Ratner, M.1
  • 25
    • 4243545125 scopus 로고    scopus 로고
    • Oxidative nucleobase modifications leading to strand scission
    • Burrows, C. J., and Muller, J. G. (1998) Oxidative nucleobase modifications leading to strand scission. Chem. Rev. 98, 1109-1151.
    • (1998) Chem. Rev , vol.98 , pp. 1109-1151
    • Burrows, C.J.1    Muller, J.G.2
  • 26
    • 0035979333 scopus 로고    scopus 로고
    • Long-range oxidative damage in DNA/RNA duplexes
    • Odom, D. T., and Barton, J. K. (2001) Long-range oxidative damage in DNA/RNA duplexes. Biochemistry 40, 8727-8737.
    • (2001) Biochemistry , vol.40 , pp. 8727-8737
    • Odom, D.T.1    Barton, J.K.2
  • 27
    • 0036569610 scopus 로고    scopus 로고
    • DNA conformational switches as sensitive electronic sensors of analytes
    • Fahlman, R. P., and Sen, D. (2002) DNA conformational switches as sensitive electronic sensors of analytes. J. Am. Chem. Soc. 124, 4610-4616.
    • (2002) J. Am. Chem. Soc , vol.124 , pp. 4610-4616
    • Fahlman, R.P.1    Sen, D.2
  • 28
    • 2942716983 scopus 로고    scopus 로고
    • DNA helix-stack switching as the basis for the design of versatile deoxyribosensors
    • Sankar, C. G., and Sen, D. (2004) DNA helix-stack switching as the basis for the design of versatile deoxyribosensors. J. Mol. Biol. 340, 459-467.
    • (2004) J. Mol. Biol , vol.340 , pp. 459-467
    • Sankar, C.G.1    Sen, D.2
  • 29
    • 45749135483 scopus 로고    scopus 로고
    • Immobilized DNA switches as electronic sensors for picomolar detection of plasma proteins
    • Huang, Y. C., Ge, B., Sen, D., and Yu, H. Z. (2008) Immobilized DNA switches as electronic sensors for picomolar detection of plasma proteins. J. Am. Chem. Soc. 130, 8023-8029.
    • (2008) J. Am. Chem. Soc , vol.130 , pp. 8023-8029
    • Huang, Y.C.1    Ge, B.2    Sen, D.3    Yu, H.Z.4
  • 30
    • 0034630963 scopus 로고    scopus 로고
    • Electron transfer in tetrads: Adjacent guanines are not hole traps in G quartets
    • Szalai, V. A., and Thorp, H. H. (2000) Electron transfer in tetrads: adjacent guanines are not hole traps in G quartets. J. Am. Chem. Soc. 122, 4524-4525.
    • (2000) J. Am. Chem. Soc , vol.122 , pp. 4524-4525
    • Szalai, V.A.1    Thorp, H.H.2
  • 31
    • 0344198178 scopus 로고    scopus 로고
    • Charge transport in DNA duplex/quadruplex conjugates
    • Delaney, S., and Barton, J. K. (2003) Charge transport in DNA duplex/quadruplex conjugates. Biochemistry 42, 14159-14165.
    • (2003) Biochemistry , vol.42 , pp. 14159-14165
    • Delaney, S.1    Barton, J.K.2
  • 32
    • 33750154642 scopus 로고    scopus 로고
    • Long-distance radical cation transport in DNA: Horizontal charge hopping in a dimeric quadruplex
    • Ndlebe, T., and Schuster, G. B. (2006) Long-distance radical cation transport in DNA: Horizontal charge hopping in a dimeric quadruplex. Org. Biomol. Chem. 4, 4015-4021.
    • (2006) Org. Biomol. Chem , vol.4 , pp. 4015-4021
    • Ndlebe, T.1    Schuster, G.B.2
  • 33
    • 16444370555 scopus 로고    scopus 로고
    • Selective guanine oxidation by UVB-irradiation in telomeric DNA
    • Kawai, K., Fujitsuka, M., and Majima, T. (2005) Selective guanine oxidation by UVB-irradiation in telomeric DNA. Chem. Commun., 1476-1477.
    • (2005) Chem. Commun , pp. 1476-1477
    • Kawai, K.1    Fujitsuka, M.2    Majima, T.3
  • 35
    • 0037142071 scopus 로고    scopus 로고
    • Crystal structure of parallel quadruplexes from human telomeric DNA
    • Parkinson, G. N., Lee, M. P., and Neidle, S. (2002) Crystal structure of parallel quadruplexes from human telomeric DNA. Nature 417, 876-880.
    • (2002) Nature , vol.417 , pp. 876-880
    • Parkinson, G.N.1    Lee, M.P.2    Neidle, S.3
  • 36
    • 47249089630 scopus 로고    scopus 로고
    • Polymorphism of human telomeric quadruplex structures
    • Dai, J., Carver, M., and Yang, D. (2008) Polymorphism of human telomeric quadruplex structures. Biochimie 90, 1172-1183.
    • (2008) Biochimie , vol.90 , pp. 1172-1183
    • Dai, J.1    Carver, M.2    Yang, D.3
  • 38
    • 23844438712 scopus 로고    scopus 로고
    • Not so crystal clear: The structure of the human telomere G-quadruplex in solution differs from that present in a crystal
    • Li, J., Correia, J. J., Wang, L., Trent, J. O., and Chaires, J. B. (2005) Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal. Nucleic Acids Res. 33, 4649-4659.
    • (2005) Nucleic Acids Res , vol.33 , pp. 4649-4659
    • Li, J.1    Correia, J.J.2    Wang, L.3    Trent, J.O.4    Chaires, J.B.5
  • 39
    • 33646943863 scopus 로고    scopus 로고
    • Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
    • Ambrus, A., Chen, D., Dai, J., Bialis, T., Jones, R. A., and Yang, D. (2006) Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution. Nucleic Acids Res. 34l, 2723-2735.
    • (2006) Nucleic Acids Res , vol.34 l , pp. 2723-2735
    • Ambrus, A.1    Chen, D.2    Dai, J.3    Bialis, T.4    Jones, R.A.5    Yang, D.6
  • 42
    • 0027123418 scopus 로고
    • NMR study of parallel-stranded tetraplex formation by the hexadeoxynucleotide d(TG4T)
    • Aboul-ela, F., Murchie, A. I. H., and Lilley, D. M. J. (1992) NMR study of parallel-stranded tetraplex formation by the hexadeoxynucleotide d(TG4T). Nature 360, 280-282.
    • (1992) Nature , vol.360 , pp. 280-282
    • Aboul-ela, F.1    Murchie, A.I.H.2    Lilley, D.M.J.3
  • 45
    • 45849101279 scopus 로고    scopus 로고
    • A guanine-linked end-effect is a sensitive reporter of charge flow through DNA and RNA double helices
    • Bergeron, L. J., Sen, K., and Sen, D. (2008) A guanine-linked end-effect is a sensitive reporter of charge flow through DNA and RNA double helices. Biochimie 90, 1064-1073.
    • (2008) Biochimie , vol.90 , pp. 1064-1073
    • Bergeron, L.J.1    Sen, K.2    Sen, D.3
  • 46
    • 0018846636 scopus 로고
    • Sequencing end-labeled DNA with base-specific chemical cleavages
    • Maxam, A. M., and Gilbert, W. (1980) Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65, 499-560.
    • (1980) Methods Enzymol , vol.65 , pp. 499-560
    • Maxam, A.M.1    Gilbert, W.2
  • 47
    • 3042734817 scopus 로고    scopus 로고
    • Effects of the photooxidant on DNA-mediated charge transport
    • Williams, T., Dohno, C., Stemp, E. D. A., and Barton, J. K. (2004) Effects of the photooxidant on DNA-mediated charge transport. J. Am. Chem. Soc. 126, 8148-8158.
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 8148-8158
    • Williams, T.1    Dohno, C.2    Stemp, E.D.A.3    Barton, J.K.4
  • 48
    • 0033485712 scopus 로고    scopus 로고
    • Long-range guanine damage in single-stranded DNA: Charge transport through a duplex bridge and in a single-stranded overhang
    • Kan, Y., and Schuster, G. B. (1999) Long-range guanine damage in single-stranded DNA: charge transport through a duplex bridge and in a single-stranded overhang. J. Am. Chem. Soc. 121, 10857-10864.
    • (1999) J. Am. Chem. Soc , vol.121 , pp. 10857-10864
    • Kan, Y.1    Schuster, G.B.2
  • 49
    • 39049183349 scopus 로고    scopus 로고
    • Structure and stability of DNA quadruplexes under molecular crowding conditions
    • Karimata, H., Miyoshi, D., and Sugimoto, N. (2005) Structure and stability of DNA quadruplexes under molecular crowding conditions. Nucleic Acids Symp. Ser. (Oxford) 49, 239-240.
    • (2005) Nucleic Acids Symp. Ser. (Oxford) , vol.49 , pp. 239-240
    • Karimata, H.1    Miyoshi, D.2    Sugimoto, N.3
  • 51
    • 38049030699 scopus 로고    scopus 로고
    • Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics
    • Patel, D. J., Phan, A. T., and Kuryavyi, V. (2007) Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res. 35, 7429-7455.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7429-7455
    • Patel, D.J.1    Phan, A.T.2    Kuryavyi, V.3
  • 52
    • 45749103733 scopus 로고    scopus 로고
    • Four-stranded nucleic acids: Structure, function and targeting of G-quadruplexes
    • Huppert, J. L. (2008) Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes. Chem. Soc. Rev. 37, 1375-1384.
    • (2008) Chem. Soc. Rev , vol.37 , pp. 1375-1384
    • Huppert, J.L.1
  • 53
    • 33846308160 scopus 로고    scopus 로고
    • Electron hole flow patterns through the RNA-cleaving 8-17 deoxyribozyme yield unusual information about its structure and folding
    • Leung, E. K. Y., and Sen, D. (2007) Electron hole flow patterns through the RNA-cleaving 8-17 deoxyribozyme yield unusual information about its structure and folding. Chem. Biol. 14, 41.
    • (2007) Chem. Biol , vol.14 , pp. 41
    • Leung, E.K.Y.1    Sen, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.