Insulin and insulin-like growth factor-I receptors differentially mediate insulin-stimulated adhesion molecule production by endothelial cells

Endocrinology

Volumn 150, Issue 8, 2009, Pages 3475-3482

  Li, Guolian ^a   Barrett, Eugene J ^a   Ko, Seung Hyun ^a   Cao, Wenhong ^b   Liu, Zhenqi ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; LEUKOCYTE ADHERENCE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOTTING, WESTERN; CATTLE; CELL ADHESION; CELL LINE; ENDOTHELIAL CELLS; HUMANS; HYPOGLYCEMIC AGENTS; IMMUNOPRECIPITATION; INSULIN; INTERCELLULAR ADHESION MOLECULE-1; MAP KINASE KINASE 1; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; RNA, SMALL INTERFERING; VASCULAR CELL ADHESION MOLECULE-1;

EID: 67651177695     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0172     Document Type: Article

References (39)

1. Nigro J, Osman N, Dart AM, Little PJ 2006 Insulin resistance and atherosclerosis. Endocr Rev 27:242-259
2. Semenkovich CF 2006 Insulin resistance and atherosclerosis. J Clin Invest 116:1813-1822
3. Kim JA, Montagnani M, Koh KK, Quon MJ 2006 Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 113:1888-1904
4. Kim JA, Koh KK, Quon MJ 2005 The union of vascular and metabolic actions of insulin in sickness and in health. ArteriosclerThrombVasc Biol 25:889-891
5. Rao RM, Yang L, Garcia-Cardena G, Luscinskas FW 2007 Endothelial-dependent mechanisms of leukocyte recruitment to the vascular wall. Circ Res 101:234-247
6. Galkina E, Ley K 2007 Vascular adhesion molecules in atherosclerosis. Arterioscler Thromb Vasc Biol 27:2292-2301
7. Cybulsky MI, Gimbrone Jr MA 1991 Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251:788-791
8. Muniyappa R, Montagnani M, Koh KK, Quon MJ 2007 Cardiovascular actions of insulin. Endocr Rev 28:463-491
9. Chen NG, Holmes M, Reaven GM 1999 Relationship between insulin resistance, soluble adhesion molecules, and mononuclear cell binding in healthy volunteers. J Clin Endocrinol Metab 84:3485-3489
10. Song Y, Manson JE, Tinker L, Rifai N, Cook NR, Hu FB, Hotamisligil GS, Ridker PM, Rodriguez BL, Margolis KL, Oberman A, Liu S 2007 Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women. Diabetes 56:1898-1904
11. Meigs JB, Hu FB, Rifai N, Manson JE 2004 Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. JAMA 291:1978-1986
12. Bannan S, Mansfield MW, Grant PJ 1998 Soluble vascular cell adhesion molecule-1 and E-selectin levels in relation to vascular risk factors and to E-selectin genotype in the first degree relatives of NIDDM patients and in NIDDM patients. Diabetologia 41:460-466
13. Desideri G, De Simone M, Iughetti L, Rosato T, Iezzi ML, Marinucci MC, Cofini V, Croce G, Passacquale G, Necozione S, Ferri C 2005 Early activation of vascular endothelial cells and platelets in obese children. J Clin Endocrinol Metab 90:3145-3152
14. Hak AE, Pols HA, Stehouwer CD, Meijer J, Kiliaan AJ, Hofman A, Breteler MM, Witteman JC 2001 Markers of inflammation and cellular adhesion molecules in relation to insulin resistance in nondiabetic elderly: the Rotterdam study. J Clin Endocrinol Metab 86:4398-4405
15. Taniguchi CM, Emanuelli B, Kahn CR 2006 Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 7:85-96
16. Zeng G, Quon MJ 1996 Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. J Clin Invest 98:894-898
17. Montagnani M, Ravichandran LV, Chen H, Esposito DL, Quon MJ 2002 Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells. Mol Endocrinol 16:1931-1942
18. Montagnani M, Chen H, Barr VA, Quon MJ 2001 Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser1179. J Biol Chem 276:30392-30398
19. Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ 2000 Roles for insulin receptor, PI3-kinase, and Akt in insulinsignaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101:1539-1545
20. Li G, Barrett EJ, Wang H, Chai W, Liu Z 2005 Insulin at physiological concentrations selectively activates insulin but not insulin-like growth factor I (IGF-I) or insulin/IGF-I hybrid receptors in endothelial cells. Endocrinology 146:4690-4696
21. Cusi K, Maezono K, Osman A, Pendergrass M, Patti ME, Pratipanawatr T, DeFronzo RA, Kahn CR, Mandarino LJ 2000 Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. J Clin Invest 105:311-320
22. Li G, Barrett EJ, Barrett MO, Cao W, Liu Z 2007 Tumor necrosis factor-α induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway. Endocrinology 148:3356-3363
23. Madonna R, Pandolfi A, Massaro M, Consoli A, De Caterina R 2004 Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogenactivated protein-kinase. Diabetologia 47:532-536
24. Montagnani M, Golovchenko I, Kim I, Koh GY, Goalstone ML, Mundhekar AN, Johansen M, Kucik DF, Quon MJ, Draznin B 2002 Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells. J Biol Chem 277:1794-1799
25. Chisalita SI, Arnqvist HJ 2004 Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells. Am J Physiol Endocrinol Metab 286:E896-E901
26. Kevil CG, Patel RP, Bullard DC 2001 Essential role of ICAM-1 in mediating monocyte adhesion to aortic endothelial cells. Am J Physiol Cell Physiol 281: C1442-C1447
27. Zarubin T, Han J 2005 Activation and signaling of the p38 MAP kinase pathway. Cell Res 15:11-18
28. Liu Z, Cao W 2009 p38 mitogen-activated protein kinase: a critical node linking insulin resistance and cardiovascular diseases in type 2 diabetes mellitus. Endocr Metab Immune Disord Drug Targets 9:38-46
29. Li J, Hu X, Selvakumar P, Russell 3rd RR, Cushman SW, Holman GD, Young LH 2004 Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle. Am J Physiol Endocrinol Metab 287:E834-E841
30. Ju H, Behm DJ, Nerurkar S, Eybye ME, Haimbach RE, Olzinski AR, Douglas SA, Willette RN 2003 p38 MAPK inhibitors ameliorate target organ damage in hypertension: Part 1. p38 MAPK-dependent endothelial dysfunction and hypertension. J Pharmacol Exp Ther 307:932-938
31. Chai W, Liu Z 2007 p38 mitogen-activated protein kinase mediates palmitateinduced apoptosis but not inhibitor of nuclear factor-KB degradation in human coronary artery endothelial cells. Endocrinology 148:1622-1628
32. Blankenberg S, Barbaux S, Tiret L 2003 Adhesion molecules and atherosclerosis. Atherosclerosis 170:191-203
33. Aljada A, Saadeh R, Assian E, Ghanim H, Dandona P 2000 Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide. J Clin Endocrinol Metab 85:2572-2575
34. Balaram SK, Agrawal DK, Allen RT, Kuszynski CA, Edwards JD 1997 Cell adhesion molecules and insulin-like growth factor-1 in vascular disease. J Vasc Surg 25:866-876
35. Balaram SK, Agrawal DK, Edwards JD 1999 Insulin like growth factor-1 activates nuclear factor-KB and increases transcription of the intercellular adhesion molecule-1 gene in endothelial cells. Cardiovasc Surg 7:91-97
36. Johansson GS, Arnqvist HJ 2006 Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 291:E1124-E1130
37. Entingh-Pearsall A, Kahn CR2004 Differential roles of the insulin and insulinlike growth factor-I (IGF-I) receptors in response to insulin and IGF-I. J Biol Chem 279:38016-38024
38. Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts Jr CT 2007 Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors. Mol Cell Biol 27:3569-3577
39. Cybulsky MI, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, Davis V, Gutierrez-Ramos JC, Connelly PW, Milstone DS 2001 A major role for VCAM-1,but not ICAM-1, in early atherosclerosis. J Clin Invest 107:1255-1262