-
1
-
-
0347854376
-
Regulation of C. elegans longevity by specific gustatory and olfactory neurons
-
Alcedo J, Kenyon C (2004) Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 41, 45-55.
-
(2004)
Neuron
, vol.41
, pp. 45-55
-
-
Alcedo, J.1
Kenyon, C.2
-
2
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, De Cabo R, Sinclair DA (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
3
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol. 2, 326-332.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
4
-
-
35348972430
-
Genetic links between diet and lifespan: Shared mechanisms from yeast to humans
-
Bishop NA, Guarente L (2007) Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat. Rev. 8, 835-844.
-
(2007)
Nat. Rev.
, vol.8
, pp. 835-844
-
-
Bishop, N.A.1
Guarente, L.2
-
5
-
-
4444231429
-
Drosophila lifespan enhancement by exogenous bacteria
-
Brummel T, Ching A, Seroude L, Simon AF, Benzer S (2004) Drosophila lifespan enhancement by exogenous bacteria. Proc. Natl Acad. Sci. USA 101, 12974-12979.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 12974-12979
-
-
Brummel, T.1
Ching, A.2
Seroude, L.3
Simon, A.F.4
Benzer, S.5
-
6
-
-
22144455725
-
Correlated responses to selection for stress resistance and longevity in a laboratory population of Drosophila melanogaster
-
Bubliy OA, Loeschcke V (2005) Correlated responses to selection for stress resistance and longevity in a laboratory population of Drosophila melanogaster. J. Evol. Biol. 18, 789-803.
-
(2005)
J. Evol. Biol.
, vol.18
, pp. 789-803
-
-
Bubliy, O.A.1
Loeschcke, V.2
-
7
-
-
0029921379
-
Age-related changes of glycosidases in human retinal pigment epithelium
-
Cingle KA, Kalski RS, Bruner WE, O'Brien CM, Erhard P, Wyszynski RE (1996) Age-related changes of glycosidases in human retinal pigment epithelium. Curr. Eye Res. 15, 433-438.
-
(1996)
Curr. Eye Res.
, vol.15
, pp. 433-438
-
-
Cingle, K.A.1
Kalski, R.S.2
Bruner, W.E.3
O'Brien, C.M.4
Erhard, P.5
Wyszynski, R.E.6
-
8
-
-
0036198149
-
Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
-
Cypser JR, Johnson TE (2002) Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity. J. Gerontol. 57, B109-B114.
-
(2002)
J. Gerontol.
, vol.57
-
-
Cypser, J.R.1
Johnson, T.E.2
-
9
-
-
0030882921
-
Dietary energy tissue-specifically regulates endoplasmic reticulum chaperone gene expression in the liver of mice
-
Dhahbi JM, Mote PL, Tillman JB, Walford RL, Spindler SR (1997) Dietary energy tissue-specifically regulates endoplasmic reticulum chaperone gene expression in the liver of mice. J. Nutr. 127, 1758-1764.
-
(1997)
J. Nutr.
, vol.127
, pp. 1758-1764
-
-
Dhahbi, J.M.1
Mote, P.L.2
Tillman, J.B.3
Walford, R.L.4
Spindler, S.R.5
-
10
-
-
0023932769
-
Effects of inhibitors of N-linked oligosaccharide processing on the biosynthesis and function of insulin and insulin-like growth factor-I receptors
-
Duronio V, Jacobs S, Romero PA, Herscovics A (1988) Effects of inhibitors of N-linked oligosaccharide processing on the biosynthesis and function of insulin and insulin-like growth factor-I receptors. J. Biol. Chem. 263, 5436-5445.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5436-5445
-
-
Duronio, V.1
Jacobs, S.2
Romero, P.A.3
Herscovics, A.4
-
11
-
-
0026317511
-
Glycosidase inhibitors: Inhibitors of N-linked oligosaccharide processing
-
Elbein AD (1991) Glycosidase inhibitors: Inhibitors of N-linked oligosaccharide processing. FASEB J. 5, 3055-3063.
-
(1991)
FASEB J.
, vol.5
, pp. 3055-3063
-
-
Elbein, A.D.1
-
13
-
-
20144366852
-
Rapid iterative negative geotaxis (RING): A new method for assessing age-related locomotor decline in Drosophila
-
Gargano JW, Martin I, Bhandari P, Grotewiel MS (2005) Rapid iterative negative geotaxis (RING): A new method for assessing age-related locomotor decline in Drosophila. Exp. Gerontol. 40, 386-395.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 386-395
-
-
Gargano, J.W.1
Martin, I.2
Bhandari, P.3
Grotewiel, M.S.4
-
14
-
-
39649110574
-
Stress-response hormesis and aging: "That which does not kill us makes us stronger"
-
Gems D, Partridge L (2008) Stress-response hormesis and aging: "that which does not kill us makes us stronger". Cell Metab. 7, 200-203.
-
(2008)
Cell Metab.
, vol.7
, pp. 200-203
-
-
Gems, D.1
Partridge, L.2
-
15
-
-
15544380902
-
Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis
-
Greene JC, Whitworth AJ, Andrews LA, Parker TJ, Pallanck LJ (2005) Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Hum. Mol. Genet. 14, 799-811.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 799-811
-
-
Greene, J.C.1
Whitworth, A.J.2
Andrews, L.A.3
Parker, T.J.4
Pallanck, L.J.5
-
16
-
-
0034838656
-
Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality control
-
Herscovics A (2001) Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality control. Biochimie 83, 757-762.
-
(2001)
Biochimie
, vol.83
, pp. 757-762
-
-
Herscovics, A.1
-
17
-
-
0028842285
-
Expression of heat shock genes in hepatocytes is affected by age and food restriction in rats
-
Heydari AR, Conrad CC, Richardson A (1995) Expression of heat shock genes in hepatocytes is affected by age and food restriction in rats. J. Nutr. 125, 410-418.
-
(1995)
J. Nutr.
, vol.125
, pp. 410-418
-
-
Heydari, A.R.1
Conrad, C.C.2
Richardson, A.3
-
18
-
-
0034981027
-
A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation
-
Hosokawa N, Wada I, Hasegawa K, Yorihuzi T, Tremblay LO, Herscovics A, Nagata K (2001) A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation. EMBO Rep. 2, 415-422.
-
(2001)
EMBO Rep.
, vol.2
, pp. 415-422
-
-
Hosokawa, N.1
Wada, I.2
Hasegawa, K.3
Yorihuzi, T.4
Tremblay, L.O.5
Herscovics, A.6
Nagata, K.7
-
19
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425, 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
20
-
-
0034919060
-
High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span
-
Landis G, Bhole D, Lu L, Tower J (2001) High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span. Genetics 158, 1167-1176.
-
(2001)
Genetics
, vol.158
, pp. 1167-1176
-
-
Landis, G.1
Bhole, D.2
Lu, L.3
Tower, J.4
-
21
-
-
0031891726
-
Geldanamycin, an hsp90/GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway
-
Lawson B, Brewer JW, Hendershot LM (1998) Geldanamycin, an hsp90/ GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway. J. Cell. Physiol. 174, 170-178.
-
(1998)
J. Cell. Physiol.
, vol.174
, pp. 170-178
-
-
Lawson, B.1
Brewer, J.W.2
Hendershot, L.M.3
-
22
-
-
34248571826
-
GRP78 induction in cancer: Therapeutic and prognostic implications
-
Lee AS (2007) GRP78 induction in cancer: Therapeutic and prognostic implications. Cancer Res. 67, 3496-3499.
-
(2007)
Cancer Res.
, vol.67
, pp. 3496-3499
-
-
Lee, A.S.1
-
23
-
-
37348999218
-
Modulation of longevity by environmental sensing
-
Libert S, Pletcher SD (2007) Modulation of longevity by environmental sensing. Cell 131, 1231-1234.
-
(2007)
Cell
, vol.131
, pp. 1231-1234
-
-
Libert, S.1
Pletcher, S.D.2
-
24
-
-
33847259770
-
Regulation of Drosophila life span by olfaction and food-derived odors
-
Libert S, Zwiener J, Chu X, Vanvoorhies W, Roman G, Pletcher SD (2007) Regulation of Drosophila life span by olfaction and food-derived odors. Science 315, 1133-1137.
-
(2007)
Science
, vol.315
, pp. 1133-1137
-
-
Libert, S.1
Zwiener, J.2
Chu, X.3
Vanvoorhies, W.4
Roman, G.5
Pletcher, S.D.6
-
26
-
-
13944249618
-
DNA repair, genome stability, and aging
-
Lombard DB, Chua KF, Mostoslavsky R, Franco S, Gostissa M, Alt FW (2005) DNA repair, genome stability, and aging. Cell 120, 497-512.
-
(2005)
Cell
, vol.120
, pp. 497-512
-
-
Lombard, D.B.1
Chua, K.F.2
Mostoslavsky, R.3
Franco, S.4
Gostissa, M.5
Alt, F.W.6
-
27
-
-
0029920370
-
Genetic analysis of ageing: Role of oxidative damage and environmental stresses
-
Martin GM, Austad SN, Johnson TE (1996) Genetic analysis of ageing: Role of oxidative damage and environmental stresses. Nat. Genet. 13, 25-34.
-
(1996)
Nat. Genet.
, vol.13
, pp. 25-34
-
-
Martin, G.M.1
Austad, S.N.2
Johnson, T.E.3
-
28
-
-
22744445281
-
Overview of caloric restriction and ageing
-
Masoro EJ (2005) Overview of caloric restriction and ageing. Mech. Ageing Dev. 126, 913-922.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 913-922
-
-
Masoro, E.J.1
-
29
-
-
37749037128
-
Dietary factors, hormesis and health
-
Mattson MP (2008) Dietary factors, hormesis and health. Ageing Res. Rev. 7, 43-48.
-
(2008)
Ageing Res. Rev.
, vol.7
, pp. 43-48
-
-
Mattson, M.P.1
-
30
-
-
0034694896
-
Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast
-
Okamura K, Kimata Y, Higashio H, Tsuru A, Kohno K (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem. Biophys. Res. Commun. 279, 445-450.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.279
, pp. 445-450
-
-
Okamura, K.1
Kimata, Y.2
Higashio, H.3
Tsuru, A.4
Kohno, K.5
-
31
-
-
34447512641
-
Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins
-
Olivari S, Molinari M (2007) Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins. FEBS Lett. 581, 3658-3664.
-
(2007)
FEBS Lett
, vol.581
, pp. 3658-3664
-
-
Olivari, S.1
Molinari, M.2
-
33
-
-
35448967382
-
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
-
Pyrko P, Schonthal AH, Hofman FM, Chen TC, Lee AS (2007) The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res. 67, 9809-9816.
-
(2007)
Cancer Res.
, vol.67
, pp. 9809-9816
-
-
Pyrko, P.1
Schonthal, A.H.2
Hofman, F.M.3
Chen, T.C.4
Lee, A.S.5
-
34
-
-
37749029855
-
Hormesis in aging
-
Rattan SI (2008) Hormesis in aging. Ageing Res. Rev. 7, 63-78.
-
(2008)
Ageing Res. Rev.
, vol.7
, pp. 63-78
-
-
Rattan, S.I.1
-
35
-
-
0032522793
-
Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster
-
Roberts DB, Mulvany WJ, Dwek RA, Rudd PM (1998) Mutant analysis reveals an alternative pathway for N-linked glycosylation in Drosophila melanogaster. Eur. J. Biochem. 253, 494-498.
-
(1998)
Eur. J. Biochem.
, vol.253
, pp. 494-498
-
-
Roberts, D.B.1
Mulvany, W.J.2
Dwek, R.A.3
Rudd, P.M.4
-
36
-
-
0029861146
-
A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
-
Rorth P (1996) A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc. Natl Acad. Sci. USA 93, 12418-12422.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 12418-12422
-
-
Rorth, P.1
-
37
-
-
22744450382
-
Toward a unified theory of caloric restriction and longevity regulation
-
Sinclair DA (2005) Toward a unified theory of caloric restriction and longevity regulation. Mech. Ageing Dev. 126, 987-1002.
-
(2005)
Mech. Ageing Dev.
, vol.126
, pp. 987-1002
-
-
Sinclair, D.A.1
-
38
-
-
33846375040
-
Diet restriction in Drosophila melanogaster. Design and analysis
-
Tatar M (2007) Diet restriction in Drosophila melanogaster. Design and analysis. Interdiscip. Top. Gerontol. 35, 115-136.
-
(2007)
Interdiscip. Top. Gerontol.
, vol.35
, pp. 115-136
-
-
Tatar, M.1
-
39
-
-
0030027642
-
Dietary energy restriction in mice negatively regulates hepatic glucose-regulated protein 78 (GRP78) expression at the posttranscriptional level
-
Tillman JB, Mote PL, Dhahbi JM, Walford RL, Spindler SR (1996) Dietary energy restriction in mice negatively regulates hepatic glucose-regulated protein 78 (GRP78) expression at the posttranscriptional level. J. Nutr. 126, 416-423.
-
(1996)
J. Nutr.
, vol.126
, pp. 416-423
-
-
Tillman, J.B.1
Mote, P.L.2
Dhahbi, J.M.3
Walford, R.L.4
Spindler, S.R.5
-
40
-
-
0037135986
-
A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response
-
Urano F, Calfon M, Yoneda T, Yun C, Kiraly M, Clark SG, Ron D (2002) A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. J. Cell Biol. 158, 639-646.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 639-646
-
-
Urano, F.1
Calfon, M.2
Yoneda, T.3
Yun, C.4
Kiraly, M.5
Clark, S.G.6
Ron, D.7
-
41
-
-
33846189368
-
Longevity and the stress response in Drosophila
-
Vermeulen CJ, Loeschcke V (2007) Longevity and the stress response in Drosophila. Exp. Gerontol. 42, 153-159.
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 153-159
-
-
Vermeulen, C.J.1
Loeschcke, V.2
-
42
-
-
27644585190
-
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
-
Viswanathan M, Kim SK, Berdichevsky A, Guarente L (2005) A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Dev. Cell 9, 605-615.
-
(2005)
Dev. Cell
, vol.9
, pp. 605-615
-
-
Viswanathan, M.1
Kim, S.K.2
Berdichevsky, A.3
Guarente, L.4
-
43
-
-
3142668925
-
Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl
-
Walker DW, Benzer S (2004) Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl. Proc. Natl Acad. Sci. USA 101, 10290-10295.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10290-10295
-
-
Walker, D.W.1
Benzer, S.2
-
44
-
-
4344591769
-
Multiple-stress analysis for isolation of Drosophila longevity genes
-
Wang HD, Kazemi-Esfarjani P, Benzer S (2004) Multiple-stress analysis for isolation of Drosophila longevity genes. Proc. Natl Acad. Sci. USA 101, 12610-12615.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 12610-12615
-
-
Wang, H.D.1
Kazemi-Esfarjani, P.2
Benzer, S.3
-
45
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D (2004) Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430, 686-689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
47
-
-
31544468900
-
Beta-mannosidosis mice: A model for the human lysosomal storage disease
-
Zhu M, Lovell KL, Patterson JS, Saunders TL, Hughes ED, Friderici KH (2006) Beta-mannosidosis mice: A model for the human lysosomal storage disease. Hum. Mol. Genet. 15, 493-500.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 493-500
-
-
Zhu, M.1
Lovell, K.L.2
Patterson, J.S.3
Saunders, T.L.4
Hughes, E.D.5
Friderici, K.H.6
-
48
-
-
0034610286
-
Genome-wide study of aging and oxidative stress response in Drosophila melanogaster
-
Zou S, Meadows S, Sharp L, Jan LY, Jan YN (2000) Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proc. Natl Acad. Sci. USA 97, 13726-13731.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 13726-13731
-
-
Zou, S.1
Meadows, S.2
Sharp, L.3
Jan, L.Y.4
Jan, Y.N.5
|