메뉴 건너뛰기




Volumn 116, Issue 7, 2009, Pages 831-839

In the rat maximal dentate activation model of partial complex epilepsy, the anticonvulsant activity of levetiracetam is modulated by nitric oxide-active drugs

Author keywords

7 Nitroindazole; Levetiracetam; Maximal dentate activation; Modulation; Nitric oxide

Indexed keywords

7 NITROINDAZOLE; ARGININE; ETIRACETAM;

EID: 67651160315     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-009-0233-x     Document Type: Article
Times cited : (16)

References (54)
  • 1
    • 0036775976 scopus 로고    scopus 로고
    • CGMP and S-nitrosylation: Two routes for modulation of neuronal excitability by NO
    • GP Ahern VA Klyachko MB Jackson 2002 cGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO Trends Neurosci 25 510 517
    • (2002) Trends Neurosci , vol.25 , pp. 510-517
    • Ahern, G.P.1    Klyachko, V.A.2    Jackson, M.B.3
  • 2
    • 0028363242 scopus 로고
    • Nitric oxide mediates the sustained opening of NMDA receptor-gated ionic channels which follows transient excitotoxic exposure in hippocampal slices
    • T Akira D Henry CG Wasterlain 1994 Nitric oxide mediates the sustained opening of NMDA receptor-gated ionic channels which follows transient excitotoxic exposure in hippocampal slices Brain Res 652 190 194
    • (1994) Brain Res , vol.652 , pp. 190-194
    • Akira, T.1    Henry, D.2    Wasterlain, C.G.3
  • 3
    • 0033845366 scopus 로고    scopus 로고
    • Nitric oxide content measured by ESR-spectroscopy in the rat brain is increased during pentylenetetrazole-induced seizures
    • V Bashkatova G Vitskova V Narkevich A Vanin V Mikoyan K Rayevsky 2000 Nitric oxide content measured by ESR-spectroscopy in the rat brain is increased during pentylenetetrazole-induced seizures J Mol Neurosci 14 183 190
    • (2000) J Mol Neurosci , vol.14 , pp. 183-190
    • Bashkatova, V.1    Vitskova, G.2    Narkevich, V.3    Vanin, A.4    Mikoyan, V.5    Rayevsky, K.6
  • 4
    • 0034748784 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of 7-nitroindazole, a selective nitric oxide synthase inhibitor, in the rat hippocampus
    • MA Bush GM Pollack 2001 Pharmacokinetics and pharmacodynamics of 7-nitroindazole, a selective nitric oxide synthase inhibitor, in the rat hippocampus Pharm Res 18 1607 1612
    • (2001) Pharm Res , vol.18 , pp. 1607-1612
    • Bush, M.A.1    Pollack, G.M.2
  • 5
    • 34247145481 scopus 로고    scopus 로고
    • Modulation of AMPA receptors in cultured cortical neurons induced by the antiepileptic drug levetiracetam
    • I Carunchio M Pieri MT Ciotti F Albo C Zona 2007 Modulation of AMPA receptors in cultured cortical neurons induced by the antiepileptic drug levetiracetam Epilepsia 48 654 662
    • (2007) Epilepsia , vol.48 , pp. 654-662
    • Carunchio, I.1    Pieri, M.2    Ciotti, M.T.3    Albo, F.4    Zona, C.5
  • 7
    • 0034646837 scopus 로고    scopus 로고
    • 7-Nitroindazole potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice
    • DOI 10.1016/S0014-2999(00)00086-8, PII S0014299900000868
    • G De Sarro P Gareri U Falconi A De Sarro 2000 7-Nitroindazole potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice Eur J Pharmacol 394 275 288 (Pubitemid 30195711)
    • (2000) European Journal of Pharmacology , vol.394 , Issue.2-3 , pp. 275-288
    • De Sarro, G.1    Gareri, P.2    Falconi, U.3    De Sarro, A.4
  • 8
    • 0036221049 scopus 로고    scopus 로고
    • A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy
    • HC Doheny MA Whittington JG Jefferys PN Patsalos 2002 A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy Br J Pharmacol 135 1425 1434
    • (2002) Br J Pharmacol , vol.135 , pp. 1425-1434
    • Doheny, H.C.1    Whittington, M.A.2    Jefferys, J.G.3    Patsalos, P.N.4
  • 9
    • 4043124791 scopus 로고    scopus 로고
    • Nitric oxide and brain hyperexcitability
    • G Ferraro P Sardo 2004 Nitric oxide and brain hyperexcitability In Vivo 18 357 366
    • (2004) In Vivo , vol.18 , pp. 357-366
    • Ferraro, G.1    Sardo, P.2
  • 10
    • 0001506685 scopus 로고    scopus 로고
    • Nitric oxide and glutamate interaction in the control of cortical and hippocampal excitability
    • G Ferraro ME Montalbano V La Grutta 1999 Nitric oxide and glutamate interaction in the control of cortical and hippocampal excitability Epilepsia 40 830 836
    • (1999) Epilepsia , vol.40 , pp. 830-836
    • Ferraro, G.1    Montalbano, M.E.2    La Grutta, V.3
  • 11
    • 84992236269 scopus 로고    scopus 로고
    • Nitric oxide and cortical, striatal and pallidal activity: Quantitative EEG analysis of surface and depth recordings
    • G Ferraro P Sardo G Di Giovanni S Galati V La Grutta 2002 Nitric oxide and cortical, striatal and pallidal activity: quantitative EEG analysis of surface and depth recordings Neurosci Res Comm 30 121 133
    • (2002) Neurosci Res Comm , vol.30 , pp. 121-133
    • Ferraro, G.1    Sardo, P.2    Di Giovanni, G.3    Galati, S.4    La Grutta, V.5
  • 13
    • 0026471112 scopus 로고
    • Ucb L059, a novel anti-convulsant drug: Pharmacological profile in animals
    • AJ Gower M Noyer R Verloes J Gobert E Wülfert 1992 Ucb L059, a novel anti-convulsant drug: pharmacological profile in animals Eur J Pharmacol 222 193 203
    • (1992) Eur J Pharmacol , vol.222 , pp. 193-203
    • Gower, A.J.1    Noyer, M.2    Verloes, R.3    Gobert, J.4    Wülfert, E.5
  • 14
    • 0028823233 scopus 로고
    • Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy
    • AJ Gower E Hirsch A Boehrer M Noyer C Marescaux 1995 Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy Epilepsy Res 22 207 213
    • (1995) Epilepsy Res , vol.22 , pp. 207-213
    • Gower, A.J.1    Hirsch, E.2    Boehrer, A.3    Noyer, M.4    Marescaux, C.5
  • 15
    • 0142102448 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of l-arginine in rats: A model of stimulated neuronal nitric oxide synthesis
    • EL Heinzen GM Pollack 2003 Pharmacokinetics and pharmacodynamics of l-arginine in rats: a model of stimulated neuronal nitric oxide synthesis Brain Res 989 67 75
    • (2003) Brain Res , vol.989 , pp. 67-75
    • Heinzen, E.L.1    Pollack, G.M.2
  • 16
    • 17744406684 scopus 로고    scopus 로고
    • Antiepileptogenesis, neuroprotection, and disease modification in the treatment of epilepsy: Focus on levetiracetam
    • H Klitgaard A Pitkänen 2003 Antiepileptogenesis, neuroprotection, and disease modification in the treatment of epilepsy: focus on levetiracetam Epileptic Disord Suppl 1 S9 S16
    • (2003) Epileptic Disord Suppl , vol.1
    • Klitgaard, H.1    Pitkänen, A.2
  • 17
    • 0032563178 scopus 로고    scopus 로고
    • Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy
    • H Klitgaard A Matagne J Gobert E Wülfert 1998 Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy Eur J Pharmacol 353 191 206
    • (1998) Eur J Pharmacol , vol.353 , pp. 191-206
    • Klitgaard, H.1    Matagne, A.2    Gobert, J.3    Wülfert, E.4
  • 18
    • 0034935392 scopus 로고    scopus 로고
    • The mechanisms of action of commonly used antiepileptic drugs
    • P Kwan GJ Sills MJ Brodie 2001 The mechanisms of action of commonly used antiepileptic drugs Pharmacol Ther 90 21 34
    • (2001) Pharmacol Ther , vol.90 , pp. 21-34
    • Kwan, P.1    Sills, G.J.2    Brodie, M.J.3
  • 19
    • 33846030193 scopus 로고    scopus 로고
    • Targets for antiepileptic drugs in the synapse
    • CJ Landmark 2007 Targets for antiepileptic drugs in the synapse Med Sci Monit 13 1 7
    • (2007) Med Sci Monit , vol.13 , pp. 1-7
    • Landmark, C.J.1
  • 21
    • 0027410987 scopus 로고
    • Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats
    • W Löscher D Hönack 1993 Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats Eur J Pharmacol 232 147 158
    • (1993) Eur J Pharmacol , vol.232 , pp. 147-158
    • Löscher, W.1    Hönack, D.2
  • 22
    • 0031908063 scopus 로고    scopus 로고
    • Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb LO59) in the kindling model of temporal lobe epilepsy
    • W Löscher D Honack C Rundfeldt 1998 Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb LO59) in the kindling model of temporal lobe epilepsy J Pharmacol Exp Ther 284 474 479
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 474-479
    • Löscher, W.1    Honack, D.2    Rundfeldt, C.3
  • 23
    • 0036193683 scopus 로고    scopus 로고
    • Selective blockade of N-type calcium channels by levetiracetam
    • EA Lukyanetz VM Shkryl PG Kostyuk 2002 Selective blockade of N-type calcium channels by levetiracetam Epilepsia 43 9 18
    • (2002) Epilepsia , vol.43 , pp. 9-18
    • Lukyanetz, E.A.1    Shkryl, V.M.2    Kostyuk, P.G.3
  • 24
    • 0034698415 scopus 로고    scopus 로고
    • Nitric oxide synthase immunoreactivity in the rat hippocampus after status epilepticus induced by perforant pathway stimulation
    • A Lumme S Soinila M Sadienemi T Halonen S Vanhatalo 2000 Nitric oxide synthase immunoreactivity in the rat hippocampus after status epilepticus induced by perforant pathway stimulation Brain Res 871 303 310
    • (2000) Brain Res , vol.871 , pp. 303-310
    • Lumme, A.1    Soinila, S.2    Sadienemi, M.3    Halonen, T.4    Vanhatalo, S.5
  • 28
    • 0033800837 scopus 로고    scopus 로고
    • Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs
    • DG Margineanu H Klitgaard 2000 Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs Pharmacol Res 42 281 285
    • (2000) Pharmacol Res , vol.42 , pp. 281-285
    • Margineanu, D.G.1    Klitgaard, H.2
  • 29
    • 0028784616 scopus 로고
    • Ucb L059, a novel anticonvulsant, reduces bicuculline-induced hyperexcitability in rat hippocampal CA3 in vivo
    • DG Margineanu E Wülfert 1995 Ucb L059, a novel anticonvulsant, reduces bicuculline-induced hyperexcitability in rat hippocampal CA3 in vivo Eur J Pharmacol 286 321 325
    • (1995) Eur J Pharmacol , vol.286 , pp. 321-325
    • Margineanu, D.G.1    Wülfert, E.2
  • 30
    • 33745039466 scopus 로고    scopus 로고
    • Nitric oxide, cell bioenergetics and neurodegeneration
    • S Moncada JP Bolaños 2006 Nitric oxide, cell bioenergetics and neurodegeneration J Neurochem 97 1676 1689
    • (2006) J Neurochem , vol.97 , pp. 1676-1689
    • Moncada, S.1    Bolaños, J.P.2
  • 31
    • 23444434659 scopus 로고
    • Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex
    • PR Montague CD Gancayco MJ Winn RB Marchase MJ Friedlander 1994 Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex Science 263 973 977
    • (1994) Science , vol.263 , pp. 973-977
    • Montague, P.R.1    Gancayco, C.D.2    Winn, M.J.3    Marchase, R.B.4    Friedlander, M.J.5
  • 32
    • 0035933671 scopus 로고    scopus 로고
    • Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices
    • I Niespodziany H Klitgaard DG Margineanu 2001 Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices Neurosci Lett 306 5 8
    • (2001) Neurosci Lett , vol.306 , pp. 5-8
    • Niespodziany, I.1    Klitgaard, H.2    Margineanu, D.G.3
  • 34
    • 0033621925 scopus 로고    scopus 로고
    • Pharmacokinetic profile of levetiracetam: Toward ideal characteristics
    • PN Patsalos 2000 Pharmacokinetic profile of levetiracetam: toward ideal characteristics Pharmacol Therapeut 85 77 85
    • (2000) Pharmacol Therapeut , vol.85 , pp. 77-85
    • Patsalos, P.N.1
  • 35
    • 0033971310 scopus 로고    scopus 로고
    • A role of nitric oxide as an inhibitor of gamma-aminobutyric acid transaminase in rat brain
    • V Paul AR Jayakumar 2000 A role of nitric oxide as an inhibitor of gamma-aminobutyric acid transaminase in rat brain Brain Res Bull 51 43 46
    • (2000) Brain Res Bull , vol.51 , pp. 43-46
    • Paul, V.1    Jayakumar, A.R.2
  • 37
    • 0030592534 scopus 로고    scopus 로고
    • The role of nitric oxide in chemically- and electrically-induced seizures in mice
    • E Przegalinski L Baran J Siwanowicz 1996 The role of nitric oxide in chemically- and electrically-induced seizures in mice Neurosci Lett 217 145 148
    • (1996) Neurosci Lett , vol.217 , pp. 145-148
    • Przegalinski, E.1    Baran, L.2    Siwanowicz, J.3
  • 39
    • 34548119524 scopus 로고    scopus 로고
    • Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat
    • P Sardo G Ferraro 2007 Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat BMC Neurosci 8 47
    • (2007) BMC Neurosci , vol.8 , pp. 47
    • Sardo, P.1    Ferraro, G.2
  • 40
    • 0036832635 scopus 로고    scopus 로고
    • Influence of nitric oxide on the spontaneous activity of globus pallidus neurones in the rat
    • P Sardo G Ferraro G Di Giovanni S Galati V La Grutta 2002 Influence of nitric oxide on the spontaneous activity of globus pallidus neurones in the rat J Neural Transm 109 1373 1389
    • (2002) J Neural Transm , vol.109 , pp. 1373-1389
    • Sardo, P.1    Ferraro, G.2    Di Giovanni, G.3    Galati, S.4    La Grutta, V.5
  • 41
    • 0037648782 scopus 로고    scopus 로고
    • Nitric oxide induced inhibition on striatal cells and excitation on globus pallidus neurons: A microiontophoretic study in the rat
    • P Sardo G Ferraro G Di Giovanni V La Grutta 2003 Nitric oxide induced inhibition on striatal cells and excitation on globus pallidus neurons: a microiontophoretic study in the rat Neurosci Lett 343 101 104
    • (2003) Neurosci Lett , vol.343 , pp. 101-104
    • Sardo, P.1    Ferraro, G.2    Di Giovanni, G.3    La Grutta, V.4
  • 42
    • 33751011634 scopus 로고    scopus 로고
    • Involvement of nitric oxide-soluble guanylyl cyclase pathway in the control of maximal dentate gyrus activation in the rat
    • P Sardo F Carletti S D'Agostino V Rizzo G Ferraro 2006 Involvement of nitric oxide-soluble guanylyl cyclase pathway in the control of maximal dentate gyrus activation in the rat J Neural Transm 113 1855 1861
    • (2006) J Neural Transm , vol.113 , pp. 1855-1861
    • Sardo, P.1    Carletti, F.2    D'Agostino, S.3    Rizzo, V.4    Ferraro, G.5
  • 43
    • 33750044044 scopus 로고    scopus 로고
    • Effects of nitric oxide-active drugs on the discharge of subthalamic neurons: Microiontophoretic evidence in the rat
    • P Sardo F Carletti S D'Agostino V Rizzo G Ferraro 2006 Effects of nitric oxide-active drugs on the discharge of subthalamic neurons: microiontophoretic evidence in the rat Eur J NeuroSci 24 1995 2002
    • (2006) Eur J NeuroSci , vol.24 , pp. 1995-2002
    • Sardo, P.1    Carletti, F.2    D'Agostino, S.3    Rizzo, V.4    Ferraro, G.5
  • 44
    • 33644688759 scopus 로고    scopus 로고
    • The discharge of subthalamic neurons is modulated by inhibiting the nitric oxide synthase in the rat
    • DOI 10.1016/j.neulet.2005.11.054, PII S0304394005013625
    • P Sardo G Ferraro F Carletti S D'Agostino V La Grutta 2006 The discharge of subthalamic neurons is modulated by inhibiting the nitric oxide synthase in the rat Neurosci Lett 396 252 256 (Pubitemid 43331041)
    • (2006) Neuroscience Letters , vol.396 , Issue.3 , pp. 252-256
    • Sardo, P.1    Ferraro, G.2    Carletti, F.3    D'Agostino, S.4    La Grutta, V.5
  • 45
    • 37749009177 scopus 로고    scopus 로고
    • Lamotrigine differently modulates 7-nitroindazole and l-arginine influence on rat maximal dentate gyrus activation
    • P Sardo S D'Agostino F Carletti V Rizzo V La Grutta G Ferraro 2008 Lamotrigine differently modulates 7-nitroindazole and l-arginine influence on rat maximal dentate gyrus activation J Neural Transm 115 27 34
    • (2008) J Neural Transm , vol.115 , pp. 27-34
    • Sardo, P.1    D'Agostino, S.2    Carletti, F.3    Rizzo, V.4    La Grutta, V.5    Ferraro, G.6
  • 47
    • 0024340386 scopus 로고
    • Maximal dentate gyrus activation: Characteristics and alterations after repeated seizures
    • JL Stringer EW Lothman 1989 Maximal dentate gyrus activation: characteristics and alterations after repeated seizures J Neurophysiol 62 136 143
    • (1989) J Neurophysiol , vol.62 , pp. 136-143
    • Stringer, J.L.1    Lothman, E.W.2
  • 48
    • 0026728535 scopus 로고
    • Reverberatory seizure discharges in hippocampal-parahippocampal circuits
    • JL Stringer EW Lothman 1992 Reverberatory seizure discharges in hippocampal-parahippocampal circuits Exp Neurol 116 198 203
    • (1992) Exp Neurol , vol.116 , pp. 198-203
    • Stringer, J.L.1    Lothman, E.W.2
  • 50
    • 0029658684 scopus 로고    scopus 로고
    • NG-nitro-l-arginine differentially affects glutamate- or kainate-induced seizures
    • P Tutka P Klonowski J Dzieciuch Z Kleinrok SJ Czuczwar 1996 NG-nitro-l-arginine differentially affects glutamate- or kainate-induced seizures Neuroreport 7 1605 1608
    • (1996) Neuroreport , vol.7 , pp. 1605-1608
    • Tutka, P.1    Klonowski, P.2    Dzieciuch, J.3    Kleinrok, Z.4    Czuczwar, S.J.5
  • 51
    • 0030951771 scopus 로고    scopus 로고
    • Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs
    • HS White 1997 Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs Epilepsia 38 9 17
    • (1997) Epilepsia , vol.38 , pp. 9-17
    • White, H.S.1
  • 52
    • 0141613677 scopus 로고    scopus 로고
    • Is nitric oxide involved in the anticonvulsant action of antiepileptic drugs?
    • K Wojtal A Gniatkowska-Nowakowska SJ Czuczwar 2003 Is nitric oxide involved in the anticonvulsant action of antiepileptic drugs? Pol J Pharmacol 55 535 542
    • (2003) Pol J Pharmacol , vol.55 , pp. 535-542
    • Wojtal, K.1    Gniatkowska-Nowakowska, A.2    Czuczwar, S.J.3
  • 53
    • 35148820640 scopus 로고    scopus 로고
    • Prolonged exposure to levetiracetam reveals a presynaptic effect on neurotransmission
    • XF Yang A Weisenfeld SM Rothman 2007 Prolonged exposure to levetiracetam reveals a presynaptic effect on neurotransmission Epilepsia 48 1861 1869
    • (2007) Epilepsia , vol.48 , pp. 1861-1869
    • Yang, X.F.1    Weisenfeld, A.2    Rothman, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.