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Volumn 114, Issue 2, 2009, Pages 360-370

IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; NUCLEOPHOSMIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; P80(NPM ALK) PROTEIN; P80(NPM-ALK) PROTEIN; PROTEIN TYROSINE KINASE;

EID: 67651115787     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-11-125658     Document Type: Article
Times cited : (51)

References (64)
  • 1
    • 0022800838 scopus 로고
    • Insulin-like growth factor I receptor primary structure: Comparison with insulin receptor suggests structural determinants that define functional specificity
    • Ullrich A, Gray A, Tam AW, et al. Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J. 1986;5:2503-2512.
    • (1986) EMBO J , vol.5 , pp. 2503-2512
    • Ullrich, A.1    Gray, A.2    Tam, A.W.3
  • 2
    • 0036782071 scopus 로고    scopus 로고
    • Structural biology of insulin and IGF1 receptors: Implications for drug design
    • DOI 10.1038/nrd917
    • De Meyts P, Whittaker J. Structural biology of insulin and IGF1 receptors: implications for drug design. Nat Rev Drug Discov. 2002;1:769-783. (Pubitemid 37361561)
    • (2002) Nature Reviews Drug Discovery , vol.1 , Issue.10 , pp. 769-783
    • De Meyts, P.1    Whittaker, J.2
  • 4
    • 0031769049 scopus 로고    scopus 로고
    • Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor
    • DOI 10.1210/en.139.3.884
    • Gual P, Baron V, Lequoy V, Van Obberghen E. Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor. Endocrinology. 1998; 139:884-893. (Pubitemid 28510102)
    • (1998) Endocrinology , vol.139 , Issue.3 , pp. 884-893
    • Gual, P.1    Baron, V.2    Lequoy, V.3    Van Obberghen, E.4
  • 5
    • 0034161544 scopus 로고    scopus 로고
    • Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
    • Nakae J, Barr V, Accili D. Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR. EMBO J. 2000;19:989-996. (Pubitemid 30119824)
    • (2000) EMBO Journal , vol.19 , Issue.5 , pp. 989-996
    • Nakae, J.1    Barr, V.2    Accili, D.3
  • 6
    • 0033018109 scopus 로고    scopus 로고
    • Mechanism of protein Kinase B activation by insulin/Insulin-like growth Factor-1 revealed by specific inhibitors of phosphoinositide 3-kinase-significance for diabetes and cancer
    • DOI 10.1016/S0163-7258(98)00071-0, PII S0163725898000710
    • Galetic I, Andjelkovic M, Meier R, Brodbeck D, Park J, Hemmings BA. Mechanism of protein kinase B activation by insulin/insulin-like growth factor-1 revealed by specific inhibitors of phosphoinositide 3-kinase-significance for diabetes and cancer. Pharmacol Ther. 1999;82:409-425. (Pubitemid 29255934)
    • (1999) Pharmacology and Therapeutics , vol.82 , Issue.2-3 , pp. 409-425
    • Galetic, I.1    Andjelkovic, M.2    Meier, R.3    Brodbeck, D.4    Park, J.5    Hemmings, B.A.6
  • 7
    • 7644223079 scopus 로고    scopus 로고
    • The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway
    • DOI 10.1038/sj.onc.1208065
    • Vasilcanu D, Girnita A, Girnita L, Vasilcanu R, Axelson M, Larsson O. The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to phosphatidyl inositol-3 kinase/Akt apoptotic pathway. Oncogene. 2004; 23:7854-7862. (Pubitemid 39457035)
    • (2004) Oncogene , vol.23 , Issue.47 , pp. 7854-7862
    • Vasilcanu, D.1    Girnita, A.2    Girnita, L.3    Vasilcanu, R.4    Axelson, M.5    Larsson, O.6
  • 8
    • 17144414465 scopus 로고    scopus 로고
    • Delayed activation of insulin-like growth factor-1 receptor/Src/ MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor
    • DOI 10.1074/jbc.M412569200
    • Criswell T, Beman M, Araki S, et al. Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Erg-1 signaling regulates clusterin expression, a pro-survival factor. J Biol Chem. 2005; 280:14212-14221. (Pubitemid 40517323)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.14 , pp. 14212-14221
    • Criswell, T.1    Beman, M.2    Araki, S.3    Leskov, K.4    Cataldo, E.5    Mayo, L.D.6    Boothman, D.A.7
  • 9
    • 0028157211 scopus 로고
    • The role of the IGF-I receptor in the growth and transformation of mammalian cells
    • Baserga R, Sell C, Porcu P, Rubini M. The role of the IGF-I receptor in the growth and transformation of mammalian cells. Cell Prolif. 1994;27:63-71. (Pubitemid 24053398)
    • (1994) Cell Proliferation , vol.27 , Issue.2 , pp. 63-71
    • Baserga, R.1    Sell, C.2    Porcu, P.3    Rubini, M.4
  • 11
    • 33846874575 scopus 로고    scopus 로고
    • The role of the IGF system in cancer growth and metastasis: Overview and recent insights
    • DOI 10.1210/er.2006-0001
    • Samani AA, Yakar S, LeRoith D, Brodt P. The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev. 2007;28:20-47. (Pubitemid 46220849)
    • (2007) Endocrine Reviews , vol.28 , Issue.1 , pp. 20-47
    • Samani, A.A.1    Yakar, S.2    Leroith, D.3    Brodt, P.4
  • 13
    • 0037444268 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor
    • Tang Y, Zhang D, Fallavollita L, Brodt P. Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor. Cancer Res. 2003;63:1166-1171. (Pubitemid 36348689)
    • (2003) Cancer Research , vol.63 , Issue.6 , pp. 1166-1171
    • Tang, Y.1    Zhang, D.2    Fallavollita, L.3    Brodt, P.4
  • 14
    • 1842833905 scopus 로고    scopus 로고
    • Functional role of α-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells
    • Guvakova MA, Adams JC, Boettiger D. Functional role of α-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J Cell Sci. 2002;115:4149-4165.
    • (2002) J Cell Sci , vol.115 , pp. 4149-4165
    • Guvakova, M.A.1    Adams, J.C.2    Boettiger, D.3
  • 15
    • 0035955627 scopus 로고    scopus 로고
    • IGF-I Receptor-induced Cell-Cell Adhesion of MCF-7 Breast Cancer Cells Requires the Expression of Junction Protein ZO-1
    • DOI 10.1074/jbc.M106673200
    • Mauro L, Bartucci M, Morelli C, Ando S, Surmacz E. IGF-I receptor-induced cell-cell adhesion of MCF-7 breast cancer cells requires the expression of junction protein ZO-1. J Biol Chem. 2001; 276:39892-39897. (Pubitemid 37391401)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.43 , pp. 39892-39897
    • Mauro, L.1    Bartucci, M.2    Morelli, C.3    Ando, S.4    Surmacz, E.5
  • 16
    • 0034115368 scopus 로고    scopus 로고
    • Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo
    • Chernicky CL, Yi L, Tan H, Gan SU, Ilan J. Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo. Cancer Gene Ther. 2000;7:384-395. (Pubitemid 30210405)
    • (2000) Cancer Gene Therapy , vol.7 , Issue.3 , pp. 384-395
    • Chernicky, C.L.1    Yi, L.2    Tan, H.3    Gan, S.U.4    Ilan, J.5
  • 17
    • 0036559535 scopus 로고    scopus 로고
    • Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
    • DOI 10.1016/S1535-6108(02)00055-7
    • Lopez T, Hanahan D. Elevated levels of the IGF-I receptor convey invasion and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell. 2002;1:339-353. (Pubitemid 41039136)
    • (2002) Cancer Cell , vol.1 , Issue.4 , pp. 339-353
    • Lopez, T.1    Hanahan, D.2
  • 18
    • 0036787432 scopus 로고    scopus 로고
    • Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines
    • Adachi Y, Lee CT, Coffee K, et al. Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines. Gastroenterology. 2002;123:1191-1204.
    • (2002) Gastroenterology , vol.123 , pp. 1191-1204
    • Adachi, Y.1    Lee, C.T.2    Coffee, K.3
  • 19
    • 0032146711 scopus 로고    scopus 로고
    • A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer
    • Dunn SE, Ehrlich M, Sharp NJ, et al. A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res. 1998;58: 3353-3361. (Pubitemid 28371076)
    • (1998) Cancer Research , vol.58 , Issue.15 , pp. 3353-3361
    • Dunn, S.E.1    Ehrlich, M.2    Sharp, N.J.H.3    Reiss, K.4    Solomon, G.5    Hawkins, R.6    Baserga, R.7    Barrett, J.C.8
  • 20
    • 0037092971 scopus 로고    scopus 로고
    • Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
    • Hellawell GO, Turner GD, Davies DR, Poulsom R, Brewster SF, Macaulay VM. Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. Cancer Res. 2002;62:2942-2950. (Pubitemid 34525783)
    • (2002) Cancer Research , vol.62 , Issue.10 , pp. 2942-2950
    • Hellawell, G.O.1    Turner, G.D.H.2    Davies, D.R.3    Poulsom, R.4    Brewster, S.F.5    Macaulay, V.M.6
  • 21
    • 0042515293 scopus 로고    scopus 로고
    • An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
    • Maloney EK, McLaughlin JL, Dagdigian NE, et al. An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res. 2003;63:5073-5083.
    • (2003) Cancer Res , vol.63 , pp. 5073-5083
    • Maloney, E.K.1    McLaughlin, J.L.2    Dagdigian, N.E.3
  • 24
    • 0029738916 scopus 로고    scopus 로고
    • Insulin-like growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis
    • Singleton JR, Randolph AE, Feldman EL. Insulinlike growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis. Cancer Res. 1996;56:4522-4529. (Pubitemid 26330465)
    • (1996) Cancer Research , vol.56 , Issue.19 , pp. 4522-4529
    • Singleton, J.R.1    Randolph, A.E.2    Feldman, E.L.3
  • 25
    • 23044493251 scopus 로고    scopus 로고
    • Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
    • DOI 10.1016/S1359-6446(05)03512-9, PII S1359644605035129
    • Hofmann F, Garcia-Echeverria C. Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer. Drug Discov Today. 2005;10: 1041-1047. (Pubitemid 41074142)
    • (2005) Drug Discovery Today , vol.10 , Issue.15 , pp. 1041-1047
    • Hofmann, F.1    Garcia-Echeverria, C.2
  • 26
    • 0242624594 scopus 로고    scopus 로고
    • Growth factor receptors as therapeutic targets: Strategies to inhibit the insulin-like growth factor I receptor
    • Surmacz E. Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor. Oncogene. 2003;22:6589-6597. (Pubitemid 37372339)
    • (2003) Oncogene , vol.22 , Issue.43 , pp. 6589-6597
    • Surmacz, E.1
  • 27
    • 0029995770 scopus 로고    scopus 로고
    • Controlling IGF-receptor function: A possible strategy for tumor therapy
    • DOI 10.1016/0167-7799(96)10023-8
    • Baserga R. Controlling IGF-receptor function: a possible strategy for tumor therapy. Trends Biotechnol. 1996;14:150-152. (Pubitemid 26162077)
    • (1996) Trends in Biotechnology , vol.14 , Issue.5 , pp. 150-152
    • Baserga, R.1
  • 29
    • 0026070118 scopus 로고
    • Growth-promoting effects of insulin-like growth factor-1 (IGF-1) on hematopoietic cells: Overexpression of introduced IGF-1 receptor abrogates interleukin-3 dependency of murine factor-dependent cells by a ligand-dependent mechanism
    • McCubrey JA, Steelman LS, MayoMW, Algate PA, Dellow RA, Kaleko M. Growth-promoting effects of insulin-like growth factor-1 (IGF-1) on hematopoietic cells: overexpression of introduced IGF-1 receptor abrogates interleukin-3 dependency of murine factor-dependent cells by a ligand-dependent mechanism. Blood. 1991;78:921-929.
    • (1991) Blood , vol.78 , pp. 921-929
    • McCubrey, J.A.1    Steelman, L.S.2    Mayo, M.W.3    Algate, P.A.4    Dellow, R.A.5    Kaleko, M.6
  • 30
    • 0026447761 scopus 로고
    • The insulin-like growth factor 1 receptor is required for the proliferation of hemopoietic cells
    • Reiss K, Porcu P, Sell C, Pietrzkowski Z, Baserga R. The insulin-like growth factor 1 receptor is required for the proliferation of hemopoietic cells. Oncogene. 1992;7:2243-2248.
    • (1992) Oncogene , vol.7 , pp. 2243-2248
    • Reiss, K.1    Porcu, P.2    Sell, C.3    Pietrzkowski, Z.4    Baserga, R.5
  • 31
    • 33745220580 scopus 로고    scopus 로고
    • Synergy between an IGF-1R antibody and Raf/MEK/ ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells
    • Bertrand FE, Steelman LS, Chappell WH, et al. Synergy between an IGF-1R antibody and Raf/MEK/ ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells. Leukemia. 2006;20:1254-1260.
    • (2006) Leukemia , vol.20 , pp. 1254-1260
    • Bertrand, F.E.1    Steelman, L.S.2    Chappell, W.H.3
  • 32
    • 0036884489 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes
    • DOI 10.1046/j.1365-2567.2002.01525.x
    • Walsh PT, Smith LM, O'Connor R. Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytes. Immunology. 2002;107:461-471. (Pubitemid 36693651)
    • (2002) Immunology , vol.107 , Issue.4 , pp. 461-471
    • Walsh, P.T.1    Smith, L.M.2    O'Connor, R.3
  • 35
    • 12144290914 scopus 로고    scopus 로고
    • Inhibition of insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
    • Mitsiades CS, Mitsiades NS, McMullan CJ, et al. Inhibition of insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell. 2004;5:221-230.
    • (2004) Cancer Cell , vol.5 , pp. 221-230
    • Mitsiades, C.S.1    Mitsiades, N.S.2    McMullan, C.J.3
  • 37
    • 0031008896 scopus 로고    scopus 로고
    • ALK the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
    • Morris SW, Naeve C, Mathew P, et al. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene. 1997;14:2175-2188. (Pubitemid 27248229)
    • (1997) Oncogene , vol.14 , Issue.18 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3    James, P.L.4    Kirstein, M.N.5    Cui, X.6    Witte, D.P.7
  • 38
    • 0002510863 scopus 로고    scopus 로고
    • Anaplastic large cell lymphoma (ALCL), ALKpositive
    • Swerdlow SH, Campo E, Harris NL, et al, eds. 4th ed. Lyon, France: International Agency for Research on Cancer (IARC)
    • Delsol G, Falini B, Muller-Hermelink HK, et al. Anaplastic large cell lymphoma (ALCL), ALKpositive. In: Swerdlow SH, Campo E, Harris NL, et al, eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed. Lyon, France: International Agency for Research on Cancer (IARC); 2008:312-316.
    • (2008) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues , pp. 312-316
    • Delsol, G.1    Falini, B.2    Muller-Hermelink, H.K.3
  • 39
    • 0028198206 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • Morris SW, Kirstein MN, Valentine MB, et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science. 1994;263:1281-1284.
    • (1994) Science , vol.263 , pp. 1281-1284
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 40
    • 0028275645 scopus 로고
    • Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3
    • Shiota M, Fujimoto J, Semba T, Satoh H, Yamamoto T, Mori S. Hyperphosphorylation of a novel 80 kDa protein-tyrosine kinase similar to Ltk in a human Ki-1 lymphoma cell line, AMS3. Oncogene. 1994;9:1567-1574. (Pubitemid 24163381)
    • (1994) Oncogene , vol.9 , Issue.6 , pp. 1567-1574
    • Shiota, M.1    Fujimoto, J.2    Semba, T.3    Satoh, H.4    Yamamoto, T.5    Mori, S.6
  • 41
    • 0030878811 scopus 로고    scopus 로고
    • Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: A distinct clinicopathologic entity
    • Shiota M, Nakamura S, Ichinohasama R, et al. Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: a distinct clinicopathologic entity. Blood. 1995;86:1954-1960. (Pubitemid 27313594)
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 3 , pp. 538-540
    • Shiota, M.1    Mori, S.2
  • 42
    • 0033561433 scopus 로고    scopus 로고
    • + lymphoma: Clinico-pathological findings and outcome
    • + lymphoma: clinico-pathological findings and outcome. Blood. 1999;93:2697-2706.
    • (1999) Blood , vol.93 , pp. 2697-2706
    • Falini, B.1    Pileri, S.2    Zinzani, P.L.3
  • 43
    • 0032533908 scopus 로고    scopus 로고
    • + anaplastic large-cell lymphoma in children: Analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology
    • + anaplastic large-cell lymphoma in children: analysis of 82 patients enrolled in two consecutive studies of the French Society of Pediatric Oncology. Blood. 1998;92:3591-3598.
    • (1998) Blood , vol.92 , pp. 3591-3598
    • Brugieres, L.1    Le Deley, M.C.2    Pacquement, H.3
  • 45
    • 20044387017 scopus 로고    scopus 로고
    • Advanced-stage large-cell lymphoma in children and adolescents: Results of a randomized trial incorporating intermediate-dose methotrexate and high-dose cytarabine in the maintenance phase of theAPO regimen: a Pediatric Oncology Group phase III trial
    • Laver JH, Kraveka JM, Hutchinson RE, et al. Advanced-stage large-cell lymphoma in children and adolescents: results of a randomized trial incorporating intermediate-dose methotrexate and high-dose cytarabine in the maintenance phase of theAPO regimen: a Pediatric Oncology Group phase III trial. J Clin Oncol. 2005;23:541-547.
    • (2005) J Clin Oncol , vol.23 , pp. 541-547
    • Laver, J.H.1    Kraveka, J.M.2    Hutchinson, R.E.3
  • 47
    • 34948834758 scopus 로고    scopus 로고
    • + anaplastic large-cell lymphoma
    • + anaplastic large-cell lymphoma. Blood. 2007;110:2259-2267.
    • (2007) Blood , vol.110 , pp. 2259-2267
    • Amin, H.M.1    Lai, R.2
  • 48
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • DOI 10.1016/0092-8674(93)90679-K
    • Liu J-P, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. Mice carrying null mutations of the genes encoding insulinlike growth factor (Igf-1) and type 1 IGF receptor (Igf1r). Cell. 1993;75:59-72. (Pubitemid 23306021)
    • (1993) Cell , vol.75 , Issue.1 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 49
    • 0026842293 scopus 로고
    • Constitutive expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor abrogates all requirements for exogenous growth factors
    • Pietrzkowski Z, Lammers R, Carpenter G, et al. Constitutive expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor abrogates all requirements for exogenous growth factors. Cell Growth Differ. 1992;3:199-205.
    • (1992) Cell Growth Differ , vol.3 , pp. 199-205
    • Pietrzkowski, Z.1    Lammers, R.2    Carpenter, G.3
  • 51
    • 33749335370 scopus 로고    scopus 로고
    • + anaplastic large-cell lymphoma cells
    • + anaplastic large-cell lymphoma cells. Blood. 2006;108:2407-2415.
    • (2006) Blood , vol.108 , pp. 2407-2415
    • Qiu, L.1    Lai, R.2    Lin, Q.3
  • 52
    • 1642494838 scopus 로고    scopus 로고
    • Cyclolignans as Inhibitors of the Insulin-Like Growth Factor-1 Receptor and Malignant Cell Growth
    • DOI 10.1158/0008-5472.CAN-03-2522
    • Girnita A, Girnita L, del Prete F, Bartolazzi A, Larsson O, Axelson M. Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth. Cancer Res. 2004;64:236-242. (Pubitemid 38114104)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 236-242
    • Girnita, A.1    Girnita, L.2    Del Prete, F.3    Bartolazzi, A.4    Larsson, O.5    Axelson, M.6
  • 53
    • 0031755958 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-γ to mediate its mitogenicity
    • Bai R-Y, Dieter P, Peschel C, Morris SW, Duyster J. Nucelophosmin- anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-γ to mediate its mitogenicity. Mol Cell Biol. 1998;12:6951-6961. (Pubitemid 28533016)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.12 , pp. 6951-6961
    • Bai, R.-Y.1    Dieter, P.2    Peschel, C.3    Morris, S.W.4    Duyster, J.5
  • 54
    • 34247849313 scopus 로고    scopus 로고
    • Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation
    • DOI 10.1038/sj.onc.1210095, PII 1210095
    • Chikamori M, Fujimoto J, Tokai-Nishizumi N, Yamamoto T. Identification of multiple SNT-binding sites on NPM-ALK oncoprotein and their involvement in cell transformation. Oncogene. 2007;26:2950-2954. (Pubitemid 46701442)
    • (2007) Oncogene , vol.26 , Issue.20 , pp. 2950-2954
    • Chikamori, M.1    Fujimoto, J.2    Tokai-Nishizumi, N.3    Yamamoto, T.4
  • 55
    • 42949162264 scopus 로고    scopus 로고
    • Characterization of some molecular mechanisms governing autoactivation of the catalytic domain of the anaplastic lymphoma kinase
    • Tartari CJ, Gunby RH, Coluccia AML, et al. Characterization of some molecular mechanisms governing autoactivation of the catalytic domain of the anaplastic lymphoma kinase. J Biol Chem. 2008;283:3743-3750.
    • (2008) J Biol Chem , vol.283 , pp. 3743-3750
    • Tartari, C.J.1    Gunby, R.H.2    Coluccia, A.M.L.3
  • 58
    • 33750083890 scopus 로고    scopus 로고
    • Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity
    • Meyn MA, Wilson MB, Abdi FA, et al. Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity. J Biol Chem. 2006;281:30907-30916.
    • (2006) J Biol Chem , vol.281 , pp. 30907-30916
    • Meyn, M.A.1    Wilson, M.B.2    Abdi, F.A.3
  • 60
    • 11244307473 scopus 로고    scopus 로고
    • Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma
    • Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma. Blood. 2005;105:827-829.
    • (2005) Blood , vol.105 , pp. 827-829
    • Rassidakis, G.Z.1    Feretzaki, M.2    Atwell, C.3
  • 61
    • 2942618200 scopus 로고    scopus 로고
    • NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a
    • DOI 10.1182/blood-2003-03-0820
    • Gu T-L, Tothova Z, Scheijen B, Griffin JD, Gilliland DG, Sternberg DW. NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a. Blood. 2004;103:4622-4629. (Pubitemid 38745994)
    • (2004) Blood , vol.103 , Issue.12 , pp. 4622-4629
    • Gu, T.-L.1    Tothova, Z.2    Scheijen, B.3    Griffin, J.D.4    Gilliland, D.G.5    Sternberg, D.W.6
  • 63
    • 77955138504 scopus 로고    scopus 로고
    • Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant chronic myeloid leukemia cells
    • Prepublished online June 5, as DOI 10.1111/j.1582-4934.2009.00795.X
    • Shi P, Chandra J, Sun X, et al. Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant chronic myeloid leukemia cells J Cell Mol Med. Prepublished online June 5, 2009, as DOI 10.1111/j.1582-4934.2009.00795.X.
    • (2009) J Cell Mol Med
    • Shi, P.1    Chandra, J.2    Sun, X.3
  • 64
    • 0034693756 scopus 로고    scopus 로고
    • The contradictions of the insulin-like growth factor 1 receptor
    • Baserga R. The contradictions of the insulin-like growth factor 1 receptor. Oncogene. 2000;19: 5574-5581.
    • (2000) Oncogene , vol.19 , pp. 5574-5581
    • Baserga, R.1


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