Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma

Oncogene

Volumn 22, Issue 35, 2003, Pages 5399-5407

  Amin, Hesham M ^a   Medeiros, L Jeffrey ^a   Ma, Yupo ^a   Feretzaki, Marianna ^a   Das, Pamela ^a   Leventaki, Vasiliki ^a   Rassidakis, George Z ^a   O'Connor, Sean L ^a   McDonnell, Timothy J ^a   Lai, Raymond ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

AG490; Anaplastic large cell lymphoma; JAK; NPM ALK; STAT

Indexed keywords

4 (3 BROMO 4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; CASPASE 3; CYCLIN D3; ENZYME INHIBITOR; HYBRID PROTEIN; JANUS KINASE; JANUS KINASE 3 INHIBITOR; JANUS KINASE INHIBITOR; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN NPM ALK; PROTEIN P21; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANAPLASTIC CARCINOMA; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; LARGE CELL LYMPHOMA; LYMPHOMA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; STEADY STATE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASES; DNA-BINDING PROTEINS; G1 PHASE; HUMANS; JANUS KINASE 3; LYMPHOMA, LARGE-CELL; PROTEIN-TYROSINE KINASES; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TYRPHOSTINS;

JANUS;

EID: 0042335770     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206849     Document Type: Article

References (51)

1. Alas S and Bonavida B. (2001). Cancer Res., 61, 5137-5144.
2. Altieri DC. (2001). Trends Mol. Med., 7, 542-547.
3. Aoki Y, Feldman GM and Tosato G. (2003). Blood, 101, 1535-1542.
4. Bai RY, Dieter P, Peschel C, Morris SW and Duyster J. (1998). Mol. Cell. Biol., 18, 6951-6961.
5. Bai RY, Ouyang T, Miething C, Morris SW, Peschel C and Duyster J. (2000). Blood, 96, 4319-4327.
6. Bischof D, Pulford K, Mason DY and Morris SW. (1997). Mol. Cell. Biol., 17, 2312-2325.
7. Borer RA, Lehner CF, Eppenberger HM and Nigg EA. (1989). Cell, 56, 379-390.
8. Bowman T, Broome MA, Sinibaldi D, Wharton W, Pledger WJ, Sedivy JM, Irby R, Yeatman T, Courtneidge SA and Jove R. (2001). Proc. Natl. Acad. Sci. USA, 98, 7319-7324.
9. Bromberg J. (2002). J. Clin. Invest., 109, 1139-1142.
10. Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C and Darnell Jr JE. (1999). Cell, 98, 295-303.
11. Burke WM, Jin X, Lin HJ, Huang M, Liu R, Reynolds RK and Lin J. (2001). Oncogene, 20, 7925-7934.
12. Coqueret O and Gascan H. (2000). J. Biol. Chem., 275, 18794-18800.
13. Delsol G, Ralfkiaer E, Stein H, Wright D and Jaffe E. (2001). Pathology and Genetics of Tumors of Haematopoietic and Lymphoid Tissues: World Health Organization Classification of Tumours Jaffe E, Harris N, Stein H and Vardiman J (eds) IARC Press: Lyon, France, pp. 230-235.
14. Epling-Burnette PK, Liu JH, Catlett-Falcone R, Turkson J, Oshiro M, Kothapalli R, Li Y, Wang JM, Yang-Yen HF, Karras J, Jove R and Loughran Jr TP. (2001a). J. Clin. Invest., 107, 351-362.
15. Epling-Burnette PK, Zhong B, Bai F, Jiang K, Bailey RD, Garcia R, Jove R, Djeu JY, Loughran Jr TP and Wei S. (2001b). J. Immunol., 166, 7486-7495.
16. Epstein AL and Kaplan HS. (1974). Cancer, 34, 1851-1872.
17. Eriksen KW, Kaltoft K, Mikkelsen G, Nielsen M, Zhang Q, Geisler C, Nissen MH, Ropke C, Wasik MA and Odum N. (2001). Leukemia, 15, 787-793.
18. Falini B, Pileri S, Zinzani PL, Carbone A, Zagonel V, Wolf-Peeters C, Verhoef G, Menestrina F, Todeschini G, Paulli M, Lazzarino M, Giardini R, Aiello A, Foss HD, Araujo I, Fizzotti M, Pelicci PG, Flenghi L, Martelli MF and Santucci A. (1999). Blood, 93, 2697-2706.
19. Fujimoto J, Shiota M, Iwahara T, Seki N, Satoh H, Mori S and Yamamoto T. (1996). Proc. Natl. Acad Sci. USA, 93, 4181-4186.
20. Fukada T, Ohtani T, Yoshida Y, Shirogane T, Nishida K, Nakajima K, Hibi M and Hirano T. (1998). EMBO J., 17, 6670-6677.
21. Gascoyne RD, Aoun P, Wu D, Chhanabhai M, Skinnider BF, Greiner TC, Morris SW, Connors JM, Vose JM, Viswanatha DS, Coldman A and Weisenburger DD. (1999). Blood, 93, 3913-3921.
22. Grad JM, Zeng XR and Boise LH. (2000). Curr. Opin. Oncol., 12, 543-549.
23. Huang M, Page C, Reynolds RK and Lin J. (2000). Gynecol. Oncol., 79, 67-73.
24. Imada K and Leonard WJ. (2000). Mol. Immunol., 37, 1-11.
25. Kijima T, Niwa H, Steinman RA, Drenning SD, Gooding WE, Wentzel AL, Xi S and Grandis JR. (2002). Cell Growth Differ., 13, 355-362.
26. Kirken RA, Erwin-Cohen R, Behbod F, Wang M, Stepkowski SM and Kahan BD. (2001). Transplant Proc., 33, 95.
27. Kube D, Holtick U, Vockerodt M, Ahmadi T, Haier B, Behrmann I, Heinrich PC, Diehl V and Tesch H. (2001). Blood, 98, 762-770.
28. Levy DE and Darnell Jr JE. (2002). Nat. Rev. Mol. Cell. Biol., 3, 651-662.
29. Liu J and Kern JA. (2002). Am. J. Respir. Cell Mol. Biol., 27, 306-313.
30. Ma Z, Cools J, Marynen P, Cui X, Siebert R, Gesk S, Schlegelberger B, Peeters B, De Wolf-Peeters C, Wlodarska I and Morris SW. (2000). Blood, 95, 2144-2149.
31. Mahboubi K, Li F, Plescia J, Kirkiles-Smith NC, Mesri M, Du Y, Carroll JM, Elias JA, Altieri DC and Pober JS. (2001). Lab. Invest., 81, 327-334.
32. Minami M, Inoue M, Wei S, Takeda K, Matsumoto M, Kishimoto T and Akira S. (1996). Proc. Natl. Acad. Sci. USA, 93, 3963-3966.
33. Morgan R, Smith SD, Hecht BK, Christy V, Mellentin JD, Warnke R and Cleary ML. (1989). Blood, 73, 2155-2164.
34. Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, Saltman DL and Look AT. (1994). Science, 263, 1281-1284.
35. Naka T, Matsumoto T, Narazaki M, Fujimoto M, Morita Y, Ohsawa Y, Saito H, Nagasawa T, Uchiyama Y and Kishimoto T. (1998). Proc. Natl. Acad. Sci. USA, 95, 15577-15582.
36. Narla RK, Liu XP, Klis D and Uckun FM. (1998). Clin. Cancer Res., 4, 2463-2471.
37. Nielsen M, Kaltoft K, Nordahl M, Ropke C, Geisler C, Mustelin T, Dobson P, Svejgaard A and Odum N. (1997). Proc. Natl. Acad. Sci. USA, 94, 6764-6769.
38. Ning ZQ, Li J, McGuinness M and Arceci RJ. (2001). Oncogene, 20, 4528-4536.
39. Pulford K, Morris SW and Mason DY. (2001). Curr. Opin. Hematol., 8, 231-236.
40. Rane SG and Reddy EP. (2002). Oncogene, 21, 3334-3358.
41. Shiota M, Nakamura S, Ichinohasama R, Abe M, Akagi T, Takeshita M, Mori N, Fujimoto J, Miyauchi J, Mikata A, Nanba K, Takami T, Yamabe H, Takano Y, Izumo T, Nagatani T, Mohri N, Nasu K, Satoh H, Katano H, Fujimoto J, Yamamoto T and Mori S. (1995). Blood, 86, 1954-1960.
42. Slupianek A, Nieborowska-Skorska M, Hoser G, Morrione A, Majewski M, Xue L, Morris SW, Wasik MA and Skorski T. (2001). Cancer Res., 61, 2194-2199.
43. Stein H, Mason DY, Gerdes J, O'Connor N, Wainscoat J, Pallesen G, Gatter K, Falini B, Delsol G, Lemke H, Schwarting R and Lennert K. (1985). Blood, 66, 848-858.
44. Sudbeck EA, Liu XP, Narla RK, Mahajan S, Ghosh S, Mao C and Uckun FM. (1999). Clin. Cancer Res., 5, 1569-1582.
45. Sun X, Layton JE, Elefanty A and Lieschke GJ. (2001). Blood, 97, 2008-2015.
46. Turturro F, Frist AY, Arnold MD, Seth P and Pulford K. (2001). Oncogene, 20, 4466-4475.
47. Uckun FM, Ek O, Liu XP and Chen CL. (1999). Clin. Cancer Res., 5, 2954-2962.
48. Wang LH, Kirken RA, Erwin RA, Yu C-R and Farrar WL. (1999). J. Immunol., 162, 3897-3904.
49. Wei LH, Kuo ML, Chen CA, Chou CH, Cheng WF, Chang MC, Su JL and Hsieh CY. (2001). Oncogene, 20, 5799-5809.
50. Zamo A, Chiarle R, Piva R, Howes J, Fan Y, Chilosi M, Levy DE and Inghirami G. (2002). Oncogene, 21, 1038-1047.
51. Zhang Q, Raghunath PN, Xue L, Majewski M, Carpentieri DF, Odum N, Morris S, Skorski T and Wasik MA. (2002). J. Immunol., 168, 466-474.