Improvement of soluble recombinant interferon-α expression by methyl α-D-glucopyranoside in araBAD promoter system of Escherichia coli

Biotechnology and Bioprocess Engineering

Volumn 14, Issue 3, 2009, Pages 274-280

  Jung, Kyung Hwan ^a   Lee, You Jin ^a   Yeon, Ji Hyeon ^a   Yoo, Sun Kyun ^b   Chung, Byeong Churl ^c  

^a Chungju National University   (South Korea)

^b Joongbu University   (South Korea)

^c Keimyung University   (South Korea)

Author keywords

araBAD promoter; Escherichia coli; Methyl D glucopyranoside; Modulation of transcription; Soluble expression of interferon

Indexed keywords

ARABAD PROMOTER; FED-BATCH CULTURES; GLUCOPYRANOSIDE; INCLUSION BODIES; L-ARABINOSE; OPTIMAL TEMPERATURE; PROTEIN EXPRESSIONS; RECOMBINANT HUMAN INTERFERON; RECOMBINANT PROTEIN; SOLUBLE EXPRESSION; SOLUBLE FRACTION;

ANTIBIOTICS; BATCH CELL CULTURE; CELL CULTURE; CELL MEMBRANES; DISSOLUTION; DISSOLVED OXYGEN; DISSOLVED OXYGEN SENSORS; ESCHERICHIA COLI; GLYCOPROTEINS; GROWTH KINETICS; MODULATION; TRANSCRIPTION;

INTERFERONS;

ALPHA METHYLGLUCOSIDE; ARABINOSE; DISSOLVED OXYGEN; ESCHERICHIA COLI PROTEIN; PROTEIN ARABAD; RECOMBINANT ALPHA INTERFERON; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL INCLUSION; CONTROLLED STUDY; ESCHERICHIA COLI; FED BATCH CULTURE; GENETIC TRANSCRIPTION; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; TEMPERATURE;

ESCHERICHIA COLI;

EID: 67651089535     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12257-008-0270-6     Document Type: Article

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