Ibuprofen modulates allosterically NO dissociation from ferrous nitrosylated human serum heme-albumin by binding to three sites

Biochemical and Biophysical Research Communications

Volumn 387, Issue 1, 2009, Pages 83-86

  Ascenzi, Paolo ^a,b   di Masi, Alessandra ^a   De Sanctis, Giampiero ^c   Coletta, Massimo ^d   Fasano, Mauro ^e  

^a ROMA TRE UNIVERSITY   (Italy)

^b NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^c UNIVERSITY OF CAMERINO   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

^e UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

Allostery; Ferrous nitrosylated human serum heme albumin; Ibuprofen dependent absorbance spectroscopic properties; Ibuprofen dependent denitrosylation; Kinetics; Thermodynamics

Indexed keywords

FERROUS ION; HEMIN; HUMAN SERUM ALBUMIN; IBUPROFEN; NITRIC OXIDE;

ABSORPTION SPECTROSCOPY; ALLOSTERISM; ARTICLE; BINDING KINETICS; DRUG PROTEIN BINDING; EQUILIBRIUM CONSTANT; NITROSYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; THERMODYNAMICS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; HEME; HUMANS; IBUPROFEN; IRON; NITRIC OXIDE; PROTEIN CONFORMATION; SERUM ALBUMIN;

EID: 67651039712     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.117     Document Type: Article

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