Phosphoinositide 3-kinase γ inhibitor ameliorates concanavalin A-induced hepatic injury in mice

Biochemical and Biophysical Research Communications

Volumn 386, Issue 4, 2009, Pages 569-574

  Wang, Zhen ling ^a   Wu, Xiao hua ^a   Song, Li fang ^a   Wang, Yong sheng ^a   Hu, Xiao hong ^a   Luo, You fu ^a   Chen, Zhi zhi ^a   Ke, Jin ^a   Peng, Xiao dong ^a   He, Chun mei ^a   Zhang, Wei ^a   Chen, Li juan ^a   Wei, Yu qua ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Concanavalin A; Hepatitis; Inflammation; Leukocyte; Phosphoinositide 3 kinase

Indexed keywords

5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; ALANINE AMINOTRANSFERASE; ALPHA ACTIN; CONCANAVALIN A; GAMMA INTERFERON; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SMOOTH MUSCLE ACTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE HEPATITIS; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOACCUMULATION; BLOOD LEVEL; CELL INFILTRATION; CHRONIC DISEASE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; LIVER FIBROSIS; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SMOOTH MUSCLE; SPLEEN CELL; SURVIVAL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE DISEASE; ANIMALS; CONCANAVALIN A; CYTOKINES; ENZYME INHIBITORS; HEPATITIS, TOXIC; ISOENZYMES; LIVER; LIVER CIRRHOSIS; MICE; MITOGENS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; QUINOXALINES; THIAZOLIDINEDIONES;

MURINAE; MUS;

EID: 67650568967     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.060     Document Type: Article

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