메뉴 건너뛰기




Volumn 4, Issue 7, 2009, Pages

Chemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary culture

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CENTRAL NERVOUS SYSTEM AGENTS; DOPAMINE TRANSPORTER; MITOGEN ACTIVATED PROTEIN KINASE 1; NEUROTROPHIN; QUINOLINE DERIVATIVE; DOPAMINE; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR;

EID: 67650559419     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006215     Document Type: Article
Times cited : (18)

References (50)
  • 1
    • 67650515275 scopus 로고    scopus 로고
    • Fahn S, Przedborski S (2000) Parkinsonism. In: Rowland LP, ed. Merrit's Neurology. Merritt's Neurology ed. New-York: Lippincott Williams & Wilkins. pp 679-693.
    • Fahn S, Przedborski S (2000) Parkinsonism. In: Rowland LP, ed. Merrit's Neurology. Merritt's Neurology ed. New-York: Lippincott Williams & Wilkins. pp 679-693.
  • 2
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39: 889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 3
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S, Cohen G (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann Neurol 32: 804-812.
    • (1992) Ann Neurol , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 5
    • 0031679149 scopus 로고    scopus 로고
    • Classification of fluctuations in patients with Parkinson's disease
    • Quinn NP (1998) Classification of fluctuations in patients with Parkinson's disease. Neurology 51: S25-29.
    • (1998) Neurology , vol.51
    • Quinn, N.P.1
  • 6
    • 0035369623 scopus 로고    scopus 로고
    • Transcription-dependent and - independent control of neuronal survival by the PI3K-Akt signaling pathway
    • Brunet A, Datta SR, Greenberg ME (2001) Transcription-dependent and - independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr Opin Neurobiol 11: 297-305.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 7
    • 0028115022 scopus 로고
    • Neurotrophin signal transduction by the Trk receptor
    • Kaplan DR, Stephens RM (1994) Neurotrophin signal transduction by the Trk receptor. J Neurobiol 25: 1404-1417.
    • (1994) J Neurobiol , vol.25 , pp. 1404-1417
    • Kaplan, D.R.1    Stephens, R.M.2
  • 8
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260: 1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 9
    • 33644976376 scopus 로고    scopus 로고
    • Continuing trials of GDNF in Parkinson's disease
    • Barker RA (2006) Continuing trials of GDNF in Parkinson's disease. Lancet Neurol 5: 285-286.
    • (2006) Lancet Neurol , vol.5 , pp. 285-286
    • Barker, R.A.1
  • 10
    • 0025850422 scopus 로고
    • Design and synthesis of a mimetic from an antibody complementarity-determining region
    • Saragovi HU, Fitzpatrick D, Raktabutr A, Nakanishi H, Kahn M, et al. (1991) Design and synthesis of a mimetic from an antibody complementarity-determining region. Science 253: 792-795.
    • (1991) Science , vol.253 , pp. 792-795
    • Saragovi, H.U.1    Fitzpatrick, D.2    Raktabutr, A.3    Nakanishi, H.4    Kahn, M.5
  • 12
    • 0036642632 scopus 로고    scopus 로고
    • Structure-activity relationship of neuritogenic spongean acetylene alcohols, lembehynes
    • Aoki S, Matsui K, Wei H, Murakami N, Kobayashi M (2002) Structure-activity relationship of neuritogenic spongean acetylene alcohols, lembehynes. Tetrahedron 58: 5417-5422.
    • (2002) Tetrahedron , vol.58 , pp. 5417-5422
    • Aoki, S.1    Matsui, K.2    Wei, H.3    Murakami, N.4    Kobayashi, M.5
  • 13
    • 0242266523 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of substituted quinolines: Potential treatment of protozoal and retroviral co-infections
    • Fakhfakh MA, Fournet A, Prina E, Mouscadet JF, Franck X, et al. (2003) Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections. Bioorg Med Chem 11: 5013-5023.
    • (2003) Bioorg Med Chem , vol.11 , pp. 5013-5023
    • Fakhfakh, M.A.1    Fournet, A.2    Prina, E.3    Mouscadet, J.F.4    Franck, X.5
  • 15
    • 50549100383 scopus 로고    scopus 로고
    • Therapeutic effect of a novel anilidoquinoline derivative, 2-(2-methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide, in Japanese encephalitis: Correlation with in vitro neuroprotection
    • Ghosh J, Swarup V, Saxena A, Das S, Hazra A, et al. (2008) Therapeutic effect of a novel anilidoquinoline derivative, 2-(2-methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide, in Japanese encephalitis: correlation with in vitro neuroprotection. Int J Antimicrob Agents 32: 349-354.
    • (2008) Int J Antimicrob Agents , vol.32 , pp. 349-354
    • Ghosh, J.1    Swarup, V.2    Saxena, A.3    Das, S.4    Hazra, A.5
  • 17
    • 38149019214 scopus 로고    scopus 로고
    • Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists
    • Seong CM, Park WK, Park CM, Kong JY, Park NS (2008) Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett 18: 738-743.
    • (2008) Bioorg Med Chem Lett , vol.18 , pp. 738-743
    • Seong, C.M.1    Park, W.K.2    Park, C.M.3    Kong, J.Y.4    Park, N.S.5
  • 18
    • 0029830647 scopus 로고    scopus 로고
    • Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons
    • Michel PP, Agid Y (1996) Chronic activation of the cyclic AMP signaling pathway promotes development and long-term survival of mesencephalic dopaminergic neurons. J Neurochem 67: 1633-1642.
    • (1996) J Neurochem , vol.67 , pp. 1633-1642
    • Michel, P.P.1    Agid, Y.2
  • 19
    • 0025278873 scopus 로고
    • Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: Selectivity and irreversibility
    • Michel PP, Dandapani BK, Knusel B, Sanchez-Ramos J, Hefti F (1990) Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility. J Neurochem 54: 1102-1109.
    • (1990) J Neurochem , vol.54 , pp. 1102-1109
    • Michel, P.P.1    Dandapani, B.K.2    Knusel, B.3    Sanchez-Ramos, J.4    Hefti, F.5
  • 20
    • 0037462337 scopus 로고    scopus 로고
    • First asymmetric synthesis of 6-hydroxy-4-sphingenine-containing ceramides. Use of chiral propargylic alcohols to prepare a lipid found in human skin
    • Chun J, Byun HS, Bittman R (2003) First asymmetric synthesis of 6-hydroxy-4-sphingenine-containing ceramides. Use of chiral propargylic alcohols to prepare a lipid found in human skin. J Org Chem 68: 348-354.
    • (2003) J Org Chem , vol.68 , pp. 348-354
    • Chun, J.1    Byun, H.S.2    Bittman, R.3
  • 21
    • 33847800586 scopus 로고
    • Saline hydrides and superbases in organic reactions. IX. Acetylene zipper. Exceptionally facile contrathermodynamic multipositional isomeriazation of alkynes with potassium 3-aminopropylamide
    • Brown CA, Yamashita A (1975) Saline hydrides and superbases in organic reactions. IX. Acetylene zipper. Exceptionally facile contrathermodynamic multipositional isomeriazation of alkynes with potassium 3-aminopropylamide. Journal of the American Chemical Society 97: 891-892.
    • (1975) Journal of the American Chemical Society , vol.97 , pp. 891-892
    • Brown, C.A.1    Yamashita, A.2
  • 22
    • 9644285669 scopus 로고
    • A convenient synthesis of acetylenes: Catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines
    • Sonogashira K, Tohda Y, Hagihara N (1975) A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines. Tetrahedron Letters 16: 4467-4470.
    • (1975) Tetrahedron Letters , vol.16 , pp. 4467-4470
    • Sonogashira, K.1    Tohda, Y.2    Hagihara, N.3
  • 23
    • 32744459401 scopus 로고
    • Oxidation of alcohols by "activated" dimethyl sulfoxide, a preparativ, steric and mechanistic study
    • Omura K, Swern D (1978) Oxidation of alcohols by "activated" dimethyl sulfoxide, a preparativ, steric and mechanistic study. Tetrahedron 34: 1651-1660.
    • (1978) Tetrahedron , vol.34 , pp. 1651-1660
    • Omura, K.1    Swern, D.2
  • 24
    • 0036460998 scopus 로고    scopus 로고
    • Toxicity of Annonaceae for dopaminergic neurons: Potential role in atypical parkinsonism in Guadeloupe
    • Lannuzel A, Michel PP, Caparros-Lefebvre D, Abaul J, Hocquemiller R, et al. (2002) Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in Guadeloupe. Mov Disord 17: 84-90.
    • (2002) Mov Disord , vol.17 , pp. 84-90
    • Lannuzel, A.1    Michel, P.P.2    Caparros-Lefebvre, D.3    Abaul, J.4    Hocquemiller, R.5
  • 25
    • 52949091483 scopus 로고    scopus 로고
    • Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels
    • Guerreiro S, Toulorge D, Hirsch E, Marien M, Sokoloff P, et al. (2008) Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol 74: 980-989.
    • (2008) Mol Pharmacol , vol.74 , pp. 980-989
    • Guerreiro, S.1    Toulorge, D.2    Hirsch, E.3    Marien, M.4    Sokoloff, P.5
  • 26
    • 9144275011 scopus 로고    scopus 로고
    • Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: Possible relevance for atypical parkinsonism in Guadeloupe
    • Champy P, Höglinger GU, Féger J, Gleye C, Hocquemiller R, et al. (2004) Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe. J Neurochem 88: 63-69.
    • (2004) J Neurochem , vol.88 , pp. 63-69
    • Champy, P.1    Höglinger, G.U.2    Féger, J.3    Gleye, C.4    Hocquemiller, R.5
  • 27
    • 34447619518 scopus 로고    scopus 로고
    • Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons
    • Escobar-Khondiker M, Hollerhage M, Muriel MP, Champy P, Bach A, et al. (2007) Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. J Neurosci 27: 7827-7837.
    • (2007) J Neurosci , vol.27 , pp. 7827-7837
    • Escobar-Khondiker, M.1    Hollerhage, M.2    Muriel, M.P.3    Champy, P.4    Bach, A.5
  • 29
    • 0001496694 scopus 로고
    • A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, et al. (1983) A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci U S A 80: 4546-4550.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5
  • 30
    • 0030885416 scopus 로고    scopus 로고
    • Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside
    • Michel PP, Ruberg M, Agid Y (1997) Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside. J Neurochem 69: 1499-1507.
    • (1997) J Neurochem , vol.69 , pp. 1499-1507
    • Michel, P.P.1    Ruberg, M.2    Agid, Y.3
  • 31
    • 7044253710 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures
    • Zhang L, Fletcher-Turner A, Marchionni MA, Apparsundaram S, Lundgren KH, et al. (2004) Neurotrophic and neuroprotective effects of the neuregulin glial growth factor-2 on dopaminergic neurons in rat primary midbrain cultures. J Neurochem 91: 1358-1368.
    • (2004) J Neurochem , vol.91 , pp. 1358-1368
    • Zhang, L.1    Fletcher-Turner, A.2    Marchionni, M.A.3    Apparsundaram, S.4    Lundgren, K.H.5
  • 32
    • 0041353623 scopus 로고    scopus 로고
    • Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes
    • Mourlevat S, Troadec JD, Ruberg M, Michel PP (2003) Prevention of dopaminergic neuronal death by cyclic AMP in mixed neuronal/glial mesencephalic cultures requires the repression of presumptive astrocytes. Mol Pharmacol 64: 578-586.
    • (2003) Mol Pharmacol , vol.64 , pp. 578-586
    • Mourlevat, S.1    Troadec, J.D.2    Ruberg, M.3    Michel, P.P.4
  • 33
    • 34548681666 scopus 로고    scopus 로고
    • Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons
    • Zhao L, Brinton RD (2007) Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons. Brain Res 1172: 48-59.
    • (2007) Brain Res , vol.1172 , pp. 48-59
    • Zhao, L.1    Brinton, R.D.2
  • 35
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan DR, Miller FD (2000) Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10: 381-391.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 36
    • 36049006160 scopus 로고    scopus 로고
    • Relating mode of action to clinical practice: Dopaminergic agents in Parkinson's disease
    • Riederer P, Gerlach M, Muller T, Reichmann H (2007) Relating mode of action to clinical practice: dopaminergic agents in Parkinson's disease. Parkinsonism Relat Disord 13: 466-479.
    • (2007) Parkinsonism Relat Disord , vol.13 , pp. 466-479
    • Riederer, P.1    Gerlach, M.2    Muller, T.3    Reichmann, H.4
  • 37
    • 38949111419 scopus 로고    scopus 로고
    • Why should we use multifunctional neuroprotective and neurorestorative drugs for Parkinson's disease?
    • Youdim MB, Geldenhuys WJ, Van der Schyf CJ (2007) Why should we use multifunctional neuroprotective and neurorestorative drugs for Parkinson's disease? Parkinsonism Relat Disord 13 Suppl 3: S281-291.
    • (2007) Parkinsonism Relat Disord , vol.13 , Issue.SUPPL. 3
    • Youdim, M.B.1    Geldenhuys, W.J.2    Van der Schyf, C.J.3
  • 38
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
    • Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, et al. (2000) Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290: 767-773.
    • (2000) Science , vol.290 , pp. 767-773
    • Kordower, J.H.1    Emborg, M.E.2    Bloch, J.3    Ma, S.Y.4    Chu, Y.5
  • 39
    • 13144282676 scopus 로고    scopus 로고
    • Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study
    • Patel NK, Bunnage M, Plaha P, Svendsen CN, Heywood P, et al. (2005) Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann Neurol 57: 298-302.
    • (2005) Ann Neurol , vol.57 , pp. 298-302
    • Patel, N.K.1    Bunnage, M.2    Plaha, P.3    Svendsen, C.N.4    Heywood, P.5
  • 40
    • 33644833272 scopus 로고    scopus 로고
    • Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
    • Lang AE, Gill S, Patel NK, Lozano A, Nutt JG, et al. (2006) Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 59: 459-466.
    • (2006) Ann Neurol , vol.59 , pp. 459-466
    • Lang, A.E.1    Gill, S.2    Patel, N.K.3    Lozano, A.4    Nutt, J.G.5
  • 41
    • 34447287862 scopus 로고    scopus 로고
    • Advances in small molecules promoting neurotrophic function
    • Price RD, Milne SA, Sharkey J, Matsuoka N (2007) Advances in small molecules promoting neurotrophic function. Pharmacol Ther 115: 292-306.
    • (2007) Pharmacol Ther , vol.115 , pp. 292-306
    • Price, R.D.1    Milne, S.A.2    Sharkey, J.3    Matsuoka, N.4
  • 42
    • 29744449650 scopus 로고    scopus 로고
    • Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: Interaction of Bcl-2 family members with PKC pathway
    • Weinreb O, Amit T, Bar-Am O, Chillag-Talmor O, Youdim MB (2005) Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway. Ann N Y Acad Sci 1053: 348-355.
    • (2005) Ann N Y Acad Sci , vol.1053 , pp. 348-355
    • Weinreb, O.1    Amit, T.2    Bar-Am, O.3    Chillag-Talmor, O.4    Youdim, M.B.5
  • 43
    • 0642303109 scopus 로고    scopus 로고
    • The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing
    • Yogev-Falach M, Amit T, Bar-Am O, Youdim MB (2003) The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing. Faseb J 17: 2325-2327.
    • (2003) Faseb J , vol.17 , pp. 2325-2327
    • Yogev-Falach, M.1    Amit, T.2    Bar-Am, O.3    Youdim, M.B.4
  • 44
    • 9744285722 scopus 로고    scopus 로고
    • Effects of indole fatty alcohols on the differentiation of neural stem cell derived neurospheres
    • Coowar D, Bouissac J, Hanbali M, Paschaki M, Mohier E, et al. (2004) Effects of indole fatty alcohols on the differentiation of neural stem cell derived neurospheres. J Med Chem 47: 6270-6282.
    • (2004) J Med Chem , vol.47 , pp. 6270-6282
    • Coowar, D.1    Bouissac, J.2    Hanbali, M.3    Paschaki, M.4    Mohier, E.5
  • 45
    • 42349100686 scopus 로고    scopus 로고
    • Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect
    • Jeanneteau F, Garabedian MJ, Chao MV (2008) Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect. Proc Natl Acad Sci U S A 105: 4862-4867.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 4862-4867
    • Jeanneteau, F.1    Garabedian, M.J.2    Chao, M.V.3
  • 46
    • 49049085537 scopus 로고    scopus 로고
    • Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function
    • Samuels IS, Karlo JC, Faruzzi AN, Pickering K, Herrup K, et al. (2008) Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci 28: 6983-6995.
    • (2008) J Neurosci , vol.28 , pp. 6983-6995
    • Samuels, I.S.1    Karlo, J.C.2    Faruzzi, A.N.3    Pickering, K.4    Herrup, K.5
  • 47
    • 0036840532 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase (ERK(1/2)) signaling pathway by cyclic AMP potentiates the neuroprotective effect of the neurotransmitter noradrenaline on dopaminergic neurons
    • Troadec JD, Marien M, Mourlevat S, Debeir T, Ruberg M, et al. (2002) Activation of the mitogen-activated protein kinase (ERK(1/2)) signaling pathway by cyclic AMP potentiates the neuroprotective effect of the neurotransmitter noradrenaline on dopaminergic neurons. Mol Pharmacol 62: 1043-1052.
    • (2002) Mol Pharmacol , vol.62 , pp. 1043-1052
    • Troadec, J.D.1    Marien, M.2    Mourlevat, S.3    Debeir, T.4    Ruberg, M.5
  • 48
    • 42049112734 scopus 로고    scopus 로고
    • MAPKs as mediators of cell fate determination: An approach to neurodegenerative diseases
    • Miloso M, Scuteri A, Foudah D, Tredici G (2008) MAPKs as mediators of cell fate determination: an approach to neurodegenerative diseases. Curr Med Chem 15: 538-548.
    • (2008) Curr Med Chem , vol.15 , pp. 538-548
    • Miloso, M.1    Scuteri, A.2    Foudah, D.3    Tredici, G.4
  • 49
    • 25844495011 scopus 로고    scopus 로고
    • Medicinal chemical properties of successful central nervous system drugs
    • Pajouhesh H, Lenz GR (2005) Medicinal chemical properties of successful central nervous system drugs. NeuroRx 2: 541-553.
    • (2005) NeuroRx , vol.2 , pp. 541-553
    • Pajouhesh, H.1    Lenz, G.R.2
  • 50
    • 34250788045 scopus 로고    scopus 로고
    • Development of a SPE/HPLC/DAD method for the determination of antileishmanial 2-substituted quinolines and metabolites in rat plasma
    • Desrivot J, Moussa F, Champy P, Fournet A, Figadere B, et al. (2007) Development of a SPE/HPLC/DAD method for the determination of antileishmanial 2-substituted quinolines and metabolites in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci 854: 230-238.
    • (2007) J Chromatogr B Analyt Technol Biomed Life Sci , vol.854 , pp. 230-238
    • Desrivot, J.1    Moussa, F.2    Champy, P.3    Fournet, A.4    Figadere, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.